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Protein

Cytochrome P450

Gene

CYP1A9

Organism
Anguilla japonica (Japanese eel)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cytochromes P450 are a group of heme-thiolate monooxygenases.UniRule annotation

Catalytic activityi

RH + [reduced NADPH--hemoprotein reductase] + O2 = ROH + [oxidized NADPH--hemoprotein reductase] + H2O.UniRule annotation

Cofactori

hemeUniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome P450UniRule annotation (EC:1.14.14.1UniRule annotation)
Gene namesi
Name:CYP1A9Imported
OrganismiAnguilla japonica (Japanese eel)Imported
Taxonomic identifieri7937 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiAnguilliformesAnguillidaeAnguilla

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 31HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, MicrosomeUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ9PTY4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG106944
KOiK07408

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR008066 Cyt_P450_E_grp-I_CYP1
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR01683 EP450ICYP1A
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

Q9PTY4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALMNLPVVG PISVCESLVA VVTVCVVYLL LRLLSTQIPE GLKRLPGPKP
60 70 80 90 100
LPIIGNVLEL SANPHLSLTA MSERYGPVFQ IQIGMRPVVV LSGGETVRQA
110 120 130 140 150
LIKQGEEFSG RPDLHSFQYI SDGKSLAFST DQAGVWRGRR KLALSALRFF
160 170 180 190 200
STIEGSSSEY SCVLEEHISK EGMYLVEQLS TVMKANGTFD PFRHIVVSVA
210 220 230 240 250
NVICGMCFGR RYSHDDQELL SIVNLSHEFS QVASTGNPAD FIPFLRFLPS
260 270 280 290 300
RTMKAFMDMN DRFTQFVQKI VREHYISYDK NNIRDITDSL IDHCEDRKLD
310 320 330 340 350
ENSNTQISDE KVVGIVNDLF GAGFDTVSTF LSWAVMYLVT YPEIQEKLHQ
360 370 380 390 400
ELREKVGMDR LPRLTDKSNL PFLEAFITEV FRHSSFVPFT IPHCTTKNTS
410 420 430 440 450
LNGFFIPKDT CVFVNQWQVN HDPTVWKEPT DFSIERFLNA DGMSINKLEA
460 470 480 490 500
EKVMMFGLGK RRCIGEAIAR SEVFLFLAIL LQRLRFYQKP GQAPDMTPEY
510
GLTMKHKRCQ LSASLRT
Length:517
Mass (Da):58,509
Last modified:May 1, 2000 - v1
Checksum:i8750609F5BA6430E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020414 mRNA Translation: BAA88242.1

Genome annotation databases

KEGGiag:BAA88242

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020414 mRNA Translation: BAA88242.1

3D structure databases

ProteinModelPortaliQ9PTY4
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGiag:BAA88242

Phylogenomic databases

HOVERGENiHBG106944
KOiK07408

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR008066 Cyt_P450_E_grp-I_CYP1
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR01683 EP450ICYP1A
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ9PTY4_ANGJA
AccessioniPrimary (citable) accession number: Q9PTY4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: February 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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