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Protein

Nicotinic acetylcholine receptor-binding protein Mnn-1A

Gene
N/A
Organism
Micrurus nigrocinctus (Central American coral snake) (Gargantilla)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds and may inhibit nicotinic acetylcholine receptors (nAChR).1 Publication

GO - Molecular functioni

Keywordsi

Molecular functionAcetylcholine receptor inhibiting toxin, Ion channel impairing toxin, Neurotoxin, Postsynaptic neurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinic acetylcholine receptor-binding protein Mnn-1A1 Publication
OrganismiMicrurus nigrocinctus (Central American coral snake) (Gargantilla)
Taxonomic identifieri8635 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaSerpentesColubroideaElapidaeElapinaeMicrurus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004080231 – ›26Nicotinic acetylcholine receptor-binding protein Mnn-1AAdd BLAST›26

Expressioni

Tissue specificityi

Expressed by the venom gland.Curated

Family & Domainsi

Sequence similaritiesi

Sequencei

Sequence statusi: Fragment.

Q9PRQ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20 
SKCRIGKDGF YSVTCTEKEN LCFTQF
Length:26
Mass (Da):3,005
Last modified:May 3, 2011 - v2
Checksum:i7031D307D8440883
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence uncertaintyi3Assigned by comparison with orthologs1
Sequence uncertaintyi15Assigned by comparison with orthologs1
Sequence uncertaintyi22Assigned by comparison with orthologs1
Non-terminal residuei261

Sequence databases

PIRiS68644

Cross-referencesi

Sequence databases

PIRiS68644

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry namei3SX1_MICNI
AccessioniPrimary (citable) accession number: Q9PRQ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: May 3, 2011
Last modified: November 22, 2017
This is version 33 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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