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UniProtKB - Q9PJU1 (CDSA_CHLMU)
Protein
Phosphatidate cytidylyltransferase
Gene
cdsA
Organism
Chlamydia muridarum (strain MoPn / Nigg)
Status
Functioni
Catalytic activityi
- EC:2.7.7.41
: CDP-diacylglycerol biosynthesis Pathwayi
This protein is involved in step 3 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate. This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.
GO - Molecular functioni
- phosphatidate cytidylyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Nucleotidyltransferase, Transferase |
Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Enzyme and pathway databases
UniPathwayi | UPA00557;UER00614 |
Names & Taxonomyi
Protein namesi | Recommended name: Phosphatidate cytidylyltransferase (EC:2.7.7.41)Alternative name(s): CDP-DAG synthase CDP-DG synthase CDP-diacylglycerol synthase Short name: CDS CDP-diglyceride pyrophosphorylase CDP-diglyceride synthase CTP:phosphatidate cytidylyltransferase |
Gene namesi | Name:cdsA Ordered Locus Names:TC_0736 |
Organismi | Chlamydia muridarum (strain MoPn / Nigg) |
Taxonomic identifieri | 243161 [NCBI] |
Taxonomic lineagei | Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane By similarity; Multi-pass membrane protein By similarity
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 24 – 44 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 97 – 117 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 124 – 144 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 151 – 171 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 202 – 222 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 232 – 252 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 277 – 297 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000090731 | 1 – 305 | Phosphatidate cytidylyltransferaseAdd BLAST | 305 |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the CDS family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0575, Bacteria |
HOGENOMi | CLU_037294_3_3_0 |
OMAi | GCIFLTM |
OrthoDBi | 1533756at2 |
i Sequence
Sequence statusi: Complete.
Q9PJU1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFDSDKNSIL QSDFCQRLVV HSLLLVFLVI LLCTSLYPSS AFIVGLLSST
60 70 80 90 100
CAAIGTYEMS SMVRMKFPFS FTRYSSIGSA IFVALTCLTA RCKMLLPEHV
110 120 130 140 150
DLIPWFFLFF WTVHLVFKSR HYKLGPIGST GLALFCMLYV SVPIRLFLHI
160 170 180 190 200
LYGFVHTDTP FIGIWWAIFL IATTKSSDIF GYFFGKAFGK KRIAPVISPN
210 220 230 240 250
KTVVGFVAGC IASILVSLIF YSHLPKSFAN QIAMPWILVA LGIILGISGF
260 270 280 290 300
FGDIIESTFK RDAQIKNSSD LESIGGMLDV LDSLLLSTPI VYAILLITQN
GTFLG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE002160 Genomic DNA Translation: AAF39546.1 |
PIRi | D81670 |
RefSeqi | WP_010231379.1, NZ_CP027217.1 |
Genome annotation databases
EnsemblBacteriai | AAF39546; AAF39546; TC_0736 |
GeneIDi | 1246099 |
KEGGi | cmu:TC_0736 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE002160 Genomic DNA Translation: AAF39546.1 |
PIRi | D81670 |
RefSeqi | WP_010231379.1, NZ_CP027217.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 243161.TC_0736 |
Genome annotation databases
EnsemblBacteriai | AAF39546; AAF39546; TC_0736 |
GeneIDi | 1246099 |
KEGGi | cmu:TC_0736 |
Phylogenomic databases
eggNOGi | COG0575, Bacteria |
HOGENOMi | CLU_037294_3_3_0 |
OMAi | GCIFLTM |
OrthoDBi | 1533756at2 |
Enzyme and pathway databases
UniPathwayi | UPA00557;UER00614 |
Family and domain databases
MobiDBi | Search... |
Entry informationi
Entry namei | CDSA_CHLMU | |
Accessioni | Q9PJU1Primary (citable) accession number: Q9PJU1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 27, 2001 |
Last sequence update: | October 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families