UniProtKB - Q9P6Q3 (BCS1_SCHPO)
Protein
Probable mitochondrial chaperone bcs1
Gene
SPAC644.07
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Chaperone necessary for the assembly of mitochondrial respiratory chain complex III.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 249 – 256 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATPase activity Source: PomBase
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- mitochondrial respiratory chain complex III assembly Source: PomBase
- protein insertion into mitochondrial inner membrane from matrix Source: GO_Central
Keywordsi
Molecular function | Chaperone |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Probable mitochondrial chaperone bcs1Alternative name(s): BCS1-like protein |
Gene namesi | ORF Names:SPAC644.07 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:SPAC644.07 |
PomBasei | SPAC644.07 |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane By similarity; Single-pass membrane protein By similarity
Mitochondrion
- mitochondrial inner membrane Source: PomBase
- mitochondrion Source: PomBase
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 20 | Mitochondrial intermembraneSequence analysisAdd BLAST | 20 | |
Transmembranei | 21 – 41 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 42 – 449 | Mitochondrial matrixSequence analysisAdd BLAST | 408 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000084776 | 1 – 449 | Probable mitochondrial chaperone bcs1Add BLAST | 449 |
Proteomic databases
MaxQBi | Q9P6Q3 |
PaxDbi | Q9P6Q3 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 280077, 9 interactors |
STRINGi | 4896.SPAC644.07.1 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0743, Eukaryota |
HOGENOMi | CLU_010189_6_2_1 |
InParanoidi | Q9P6Q3 |
OMAi | VQGHFML |
PhylomeDBi | Q9P6Q3 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR014851, BCS1_N IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF08740, BCS1_N, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit SM01024, BCS1_N, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00674, AAA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9P6Q3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDNIGAADAA TSSGISGLLS GNSFLGAGIG LMGFGAGLAI LRRGLISGAS
60 70 80 90 100
LVKRRMLVSV EIPSKEKSYN AFLHWMSTVP KRYSNQLAVE SNRQLKMPQN
110 120 130 140 150
AREKPDKQVA NRIFSLVPGP GKHYIKYKKC WIQVERERSN RLQDLTTGTP
160 170 180 190 200
WETITLTTLS RDRGIFSELL LEAQKFMQSA QKNKTTIYTA WATEWKPFGH
210 220 230 240 250
PRSKRMLSSV VLESNVKKMI TDDVHDFLRN SQWYDTRGIP YRRGYLLYGP
260 270 280 290 300
PGSGKTSFLY ALAGELDYDI CVLNLAEKGL TDDRLNHLLS NVPPKAVVLL
310 320 330 340 350
EDVDSAFQGR ERSGEVGFHA NVTFSGLLNA LDGVTSSDER IIFMTTNHPE
360 370 380 390 400
KLDPALVRPG RVDVKAYLGN ATPEQVREMF TRFYGHSPEM ADDLSDIVCP
410 420 430 440
KNTSMASLQG LFVMNKSSPA DAVDMAKELP DNPPSTPFSF NVHRKSLSV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 113 | I → F in BAA13798 (PubMed:9501991).Curated | 1 | |
Sequence conflicti | 412 | F → L in BAA13798 (PubMed:9501991).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB90134.1 D89136 mRNA Translation: BAA13798.1 |
PIRi | T42406 |
RefSeqi | NP_593875.1, NM_001019305.2 |
Genome annotation databases
EnsemblFungii | SPAC644.07.1; SPAC644.07.1:pep; SPAC644.07 |
GeneIDi | 2543663 |
KEGGi | spo:SPAC644.07 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB90134.1 D89136 mRNA Translation: BAA13798.1 |
PIRi | T42406 |
RefSeqi | NP_593875.1, NM_001019305.2 |
3D structure databases
SMRi | Q9P6Q3 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 280077, 9 interactors |
STRINGi | 4896.SPAC644.07.1 |
Proteomic databases
MaxQBi | Q9P6Q3 |
PaxDbi | Q9P6Q3 |
Genome annotation databases
EnsemblFungii | SPAC644.07.1; SPAC644.07.1:pep; SPAC644.07 |
GeneIDi | 2543663 |
KEGGi | spo:SPAC644.07 |
Organism-specific databases
EuPathDBi | FungiDB:SPAC644.07 |
PomBasei | SPAC644.07 |
Phylogenomic databases
eggNOGi | KOG0743, Eukaryota |
HOGENOMi | CLU_010189_6_2_1 |
InParanoidi | Q9P6Q3 |
OMAi | VQGHFML |
PhylomeDBi | Q9P6Q3 |
Miscellaneous databases
PROi | PR:Q9P6Q3 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR014851, BCS1_N IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF08740, BCS1_N, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit SM01024, BCS1_N, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00674, AAA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BCS1_SCHPO | |
Accessioni | Q9P6Q3Primary (citable) accession number: Q9P6Q3 Secondary accession number(s): P78787 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 29, 2004 |
Last sequence update: | October 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families