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UniProtKB - Q9P6I3 (YHG7_SCHPO)
Protein
Putative mannan endo-1,6-alpha-mannosidase C1198.07c
Gene
SPBC1198.07c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Catalytic activityi
- Random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans. EC:3.2.1.101
GO - Molecular functioni
- mannan endo-1,6-alpha-mannosidase activity Source: PomBase
GO - Biological processi
- cellular oligosaccharide catabolic process Source: PomBase
- fungal-type cell wall biogenesis Source: PomBase
Keywordsi
Molecular function | Glycosidase, Hydrolase |
Protein family/group databases
CAZyi | GH76, Glycoside Hydrolase Family 76 |
Names & Taxonomyi
Protein namesi | Recommended name: Putative mannan endo-1,6-alpha-mannosidase C1198.07c (EC:3.2.1.101)Alternative name(s): Endo-alpha-1->6-D-mannanase C1198.07c |
Gene namesi | ORF Names:SPBC1198.07c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC1198.07c |
VEuPathDBi | FungiDB:SPBC1198.07c |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Single-pass type I membrane protein 1 Publication
Endoplasmic reticulum
- endoplasmic reticulum Source: PomBase
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Plasma Membrane
- anchored component of external side of plasma membrane Source: PomBase
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 20 – 421 | LumenalSequence analysisAdd BLAST | 402 | |
Transmembranei | 422 – 442 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_0000012130 | 20 – 442 | Putative mannan endo-1,6-alpha-mannosidase C1198.07cAdd BLAST | 423 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 75 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 124 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 193 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 229 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 254 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 257 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 356 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
MaxQBi | Q9P6I3 |
PaxDbi | Q9P6I3 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glycosyl hydrolase 76 family.Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QSWP, Eukaryota |
HOGENOMi | CLU_025694_1_2_1 |
InParanoidi | Q9P6I3 |
OMAi | TARWDTT |
Family and domain databases
InterProi | View protein in InterPro IPR008928, 6-hairpin_glycosidase_sf IPR005198, Glyco_hydro_76 IPR014480, Mannan-1_6-alpha_mannosidase |
PANTHERi | PTHR12145, PTHR12145, 1 hit |
Pfami | View protein in Pfam PF03663, Glyco_hydro_76, 1 hit |
PIRSFi | PIRSF016302, Man_a_manosd, 1 hit |
SUPFAMi | SSF48208, SSF48208, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9P6I3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRYLSFFFEF FFLFSFAFAF DFDVTSDDSI NSALTTVTDG MLNYYQSTSH
60 70 80 90 100
TFTAYWWMTG AGLNSMTDTY AATGNTTHLD MLISALVANK GDNNDYAPNS
110 120 130 140 150
EKFDLGNDDQ GIWGLSAMSA AEVNMTTGDS SASFTELAQA VFNEIMSRWD
160 170 180 190 200
TSSCGGGVRW QIYSFNNGYS YKNSISNGIL FQLAARLARY TNNDTYVDLA
210 220 230 240 250
QKVWDWSTTV GFVDLDDYTV YDGASVTSNC SSITNEQWSY NVGVYLAGTA
260 270 280 290 300
FLYNYTNGSS VWQTHMEGLM NKALDYYFTS DKIIYEPSCE PTESCNSDQT
310 320 330 340 350
AFKGMLARFL GYTMQLAPYT VETILPYIQS SAEAAALACS GGSDGVTCGY
360 370 380 390 400
MWYWNNGTWD DHYGLGEQIS AVETFQALLA QQSATILTLD TGASSESNPD
410 420 430 440
AGTDDGDTVT ITPATKSDKG WAGFLTFAFS FVFLLFSIWL YF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAB91182.2 |
RefSeqi | NP_595076.2, NM_001020982.2 |
Genome annotation databases
EnsemblFungii | SPBC1198.07c.1; SPBC1198.07c.1:pep; SPBC1198.07c |
GeneIDi | 2539836 |
KEGGi | spo:SPBC1198.07c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAB91182.2 |
RefSeqi | NP_595076.2, NM_001020982.2 |
3D structure databases
SMRi | Q9P6I3 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4896.SPBC1198.07c.1 |
Protein family/group databases
CAZyi | GH76, Glycoside Hydrolase Family 76 |
Proteomic databases
MaxQBi | Q9P6I3 |
PaxDbi | Q9P6I3 |
Genome annotation databases
EnsemblFungii | SPBC1198.07c.1; SPBC1198.07c.1:pep; SPBC1198.07c |
GeneIDi | 2539836 |
KEGGi | spo:SPBC1198.07c |
Organism-specific databases
PomBasei | SPBC1198.07c |
VEuPathDBi | FungiDB:SPBC1198.07c |
Phylogenomic databases
eggNOGi | ENOG502QSWP, Eukaryota |
HOGENOMi | CLU_025694_1_2_1 |
InParanoidi | Q9P6I3 |
OMAi | TARWDTT |
Miscellaneous databases
PROi | PR:Q9P6I3 |
Family and domain databases
InterProi | View protein in InterPro IPR008928, 6-hairpin_glycosidase_sf IPR005198, Glyco_hydro_76 IPR014480, Mannan-1_6-alpha_mannosidase |
PANTHERi | PTHR12145, PTHR12145, 1 hit |
Pfami | View protein in Pfam PF03663, Glyco_hydro_76, 1 hit |
PIRSFi | PIRSF016302, Man_a_manosd, 1 hit |
SUPFAMi | SSF48208, SSF48208, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YHG7_SCHPO | |
Accessioni | Q9P6I3Primary (citable) accession number: Q9P6I3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 31, 2004 |
Last sequence update: | July 11, 2012 | |
Last modified: | September 29, 2021 | |
This is version 113 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries - SIMILARITY comments
Index of protein domains and families