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UniProtKB - Q9P3U7 (GHT8_SCHPO)
Protein
Probable high-affinity hexose transporter ght8, mitochondrial
Gene
ght8
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
GO - Molecular functioni
- carbohydrate:proton symporter activity Source: GO_Central
GO - Biological processi
- carbohydrate transmembrane transport Source: PomBase
- carbohydrate transport Source: GO_Central
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Probable high-affinity hexose transporter ght8, mitochondrialShort name: Hexose transporter 8 |
Gene namesi | Name:ght8 ORF Names:SPCC548.06c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPCC548.06c, ght8 |
VEuPathDBi | FungiDB:SPCC548.06c |
Subcellular locationi
Mitochondrion
- Mitochondrion membrane 1 Publication; Multi-pass membrane protein 1 Publication
Mitochondrion
- mitochondrial membrane Source: UniProtKB-SubCell
Plasma Membrane
- integral component of plasma membrane Source: PomBase
- plasma membrane Source: PomBase
Other locations
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 22 – 86 | Mitochondrial intermembraneSequence analysisAdd BLAST | 65 | |
Transmembranei | 87 – 107 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 108 – 112 | CytoplasmicSequence analysis | 5 | |
Transmembranei | 113 – 133 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 134 – 144 | Mitochondrial intermembraneSequence analysisAdd BLAST | 11 | |
Transmembranei | 145 – 165 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 166 – 179 | CytoplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 180 – 200 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 201 – 304 | Mitochondrial intermembraneSequence analysisAdd BLAST | 104 | |
Transmembranei | 305 – 325 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 326 – 328 | CytoplasmicSequence analysis | 3 | |
Transmembranei | 329 – 349 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 350 – 363 | Mitochondrial intermembraneSequence analysisAdd BLAST | 14 | |
Transmembranei | 364 – 384 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 385 – 404 | CytoplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 405 – 425 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 426 – 432 | Mitochondrial intermembraneSequence analysis | 7 | |
Transmembranei | 433 – 453 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 454 – 547 | CytoplasmicSequence analysisAdd BLAST | 94 |
Keywords - Cellular componenti
Membrane, MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 21 | MitochondrionSequence analysisAdd BLAST | 21 | |
ChainiPRO_0000310744 | 22 – 547 | Probable high-affinity hexose transporter ght8, mitochondrialAdd BLAST | 526 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 519 | Phosphoserine1 Publication | 1 | |
Modified residuei | 523 | Phosphothreonine1 Publication | 1 | |
Modified residuei | 526 | Phosphothreonine1 Publication | 1 | |
Modified residuei | 527 | Phosphoserine1 Publication | 1 | |
Modified residuei | 528 | Phosphoserine1 Publication | 1 | |
Modified residuei | 529 | Phosphoserine1 Publication | 1 | |
Modified residuei | 537 | Phosphoserine1 Publication | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
MaxQBi | Q9P3U7 |
PaxDbi | Q9P3U7 |
PTM databases
iPTMneti | Q9P3U7 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 482 – 547 | DisorderedSequence analysisAdd BLAST | 66 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 513 – 534 | Polar residuesSequence analysisAdd BLAST | 22 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transit peptide, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | Q9P3U7 |
OMAi | LAMREDW |
PhylomeDBi | Q9P3U7 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9P3U7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKTLTIVML VFVSMAGWMF GADTGSIGGI TNMRDFQSRF ADRYNPVTDT
60 70 80 90 100
YSYSSARQGL ITGMVNVGSM TGCILSSPLM DRIGKRVSIM FWTIVYLIGI
110 120 130 140 150
ILQVTAVPSW VQIMVAKIWT GLAIGALSVL APGFQSEVAP ATLRGTIVTT
160 170 180 190 200
YQLAVTGGIF IAACINMGTH KLHKTAQWRV SMGINLLWGI IMFIGISFLP
210 220 230 240 250
ESPRYLIAIG KDEEALDIMC KNNVLPREHE IIQTEYHVIK TDCEAEMAGG
260 270 280 290 300
PATWGDILGA DIRYRTFLGL GVMSLQQLTG DNYYFYYGFE VFEGTGMNSP
310 320 330 340 350
YLSALILDAV NFGCTFGGLF VLEFFGRRMP LIIGGVWQSI TFFIYAAVGN
360 370 380 390 400
RALTRKNGTS NHRAGAVMIV FSCLFIFSFA QTWGPAAYVI VGESYPIRYR
410 420 430 440 450
SKCAAVATTG NWLWGFLITF FTPFISDSIG FKYGYIFAAC NLCAACIIFL
460 470 480 490 500
FAHETKGLTL EEINELYLSG AKPWMPRPEN LGQAAKQQQE VLEKSRGVQG
510 520 530 540
ESAAHLENVD NEGMEDTSSN DITSSTSSSE GRAKPESNYV DEQDRYA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329672 Genomic DNA Translation: CAB94948.1 |
RefSeqi | NP_587746.1, NM_001022740.2 |
Genome annotation databases
EnsemblFungii | SPCC548.06c.1; SPCC548.06c.1:pep; SPCC548.06c |
GeneIDi | 2539300 |
KEGGi | spo:SPCC548.06c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329672 Genomic DNA Translation: CAB94948.1 |
RefSeqi | NP_587746.1, NM_001022740.2 |
3D structure databases
SMRi | Q9P3U7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4896.SPCC548.06c.1 |
PTM databases
iPTMneti | Q9P3U7 |
Proteomic databases
MaxQBi | Q9P3U7 |
PaxDbi | Q9P3U7 |
Genome annotation databases
EnsemblFungii | SPCC548.06c.1; SPCC548.06c.1:pep; SPCC548.06c |
GeneIDi | 2539300 |
KEGGi | spo:SPCC548.06c |
Organism-specific databases
PomBasei | SPCC548.06c, ght8 |
VEuPathDBi | FungiDB:SPCC548.06c |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | Q9P3U7 |
OMAi | LAMREDW |
PhylomeDBi | Q9P3U7 |
Miscellaneous databases
PROi | PR:Q9P3U7 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GHT8_SCHPO | |
Accessioni | Q9P3U7Primary (citable) accession number: Q9P3U7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 13, 2007 |
Last sequence update: | October 1, 2000 | |
Last modified: | February 23, 2022 | |
This is version 131 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families