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UniProtKB - Q9P3U6 (GHT1_SCHPO)
Protein
High-affinity glucose transporter ght1
Gene
ght1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
High-affinity glucose transporter.
GO - Molecular functioni
- carbohydrate:proton symporter activity Source: GO_Central
- high-affinity glucose:proton symporter activity Source: PomBase
GO - Biological processi
- carbohydrate transport Source: GO_Central
- glucose import across plasma membrane Source: PomBase
Keywordsi
Biological process | Sugar transport, Transport |
Protein family/group databases
TCDBi | 2.A.1.1.112, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: High-affinity glucose transporter ght1Alternative name(s): Hexose transporter 1 |
Gene namesi | Name:ght1 ORF Names:SPCC548.07c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPCC548.07c, ght1 |
VEuPathDBi | FungiDB:SPCC548.07c |
Subcellular locationi
Other locations
Plasma Membrane
- integral component of plasma membrane Source: PomBase
- plasma membrane Source: PomBase
- plasma membrane of cell tip Source: PomBase
Other locations
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 9 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 10 – 30 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 31 – 58 | ExtracellularSequence analysisAdd BLAST | 28 | |
Transmembranei | 59 – 79 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 80 – 87 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 88 – 108 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 109 – 112 | ExtracellularSequence analysis | 4 | |
Transmembranei | 113 – 133 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 134 – 144 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 145 – 165 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 166 – 179 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 180 – 200 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 201 – 266 | CytoplasmicSequence analysisAdd BLAST | 66 | |
Transmembranei | 267 – 285 | Helical; Name=7Sequence analysisAdd BLAST | 19 | |
Topological domaini | 286 – 301 | ExtracellularSequence analysisAdd BLAST | 16 | |
Transmembranei | 302 – 322 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Topological domaini | 323 – 328 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 329 – 349 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Topological domaini | 350 – 363 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 364 – 384 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Topological domaini | 385 – 404 | CytoplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 405 – 425 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 426 – 432 | ExtracellularSequence analysis | 7 | |
Transmembranei | 433 – 453 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 454 – 557 | CytoplasmicSequence analysisAdd BLAST | 104 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050409 | 1 – 557 | High-affinity glucose transporter ght1Add BLAST | 557 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 357 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Post-translational modificationi
Not glycosylated.
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q9P3U6 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 275316, 6 interactors |
STRINGi | 4896.SPCC548.07c.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 482 – 557 | DisorderedSequence analysisAdd BLAST | 76 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 482 – 513 | Basic and acidic residuesSequence analysisAdd BLAST | 32 | |
Compositional biasi | 530 – 546 | Basic and acidic residuesSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | Q9P3U6 |
OMAi | IVGCINW |
PhylomeDBi | Q9P3U6 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9P3U6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKTLTITML LFVSMAGWMF GADTGSIGGI TNMRDFQSRF ADRYNPVTDT
60 70 80 90 100
YSYSSARQGL ITGMVNVGSF FGCLISSPTT DRIGKRNSII GFCVIYLIGV
110 120 130 140 150
IIQVTAVPSW VQIMVAKIWT GLGIGALSVL APGYQSEVAP PHIRGTIVVT
160 170 180 190 200
YQLCVTAGIF IAACINMGTH KLYKTAQWRV SIGINLLWGI ITLVGVSFLS
210 220 230 240 250
ESPRYLVSIG KDDEAIQVMC KNAELPPDSD IIQTEYKQIK SDCEAAVEGG
260 270 280 290 300
PCTWPEIFGK EIRYRTFLGM AIMSFNQLTG CNYYFYYGTQ VFKGTGMESP
310 320 330 340 350
YLASLILDAV NFGCTFGGLF VLEYCGRRVP LIIGGVWQSI CFFIYAAVGN
360 370 380 390 400
RALTRKNGTS NHRAGAVMIV FSCLFIFSFA QTWGPAAYVI VGESYPIRYR
410 420 430 440 450
SKCAAVATTS NWLWNFLISF FTPFITNSIG FKYGYIFASC NLCASIVTFL
460 470 480 490 500
FAHESKGLTL EEINELYLSD AKPWMSRPKN LSEMAEAKEV EREETRPKGE
510 520 530 540 550
SARYLEHADS NSDSEDLSSS ANNDVHEPVA RQDPFNENEV EKSRTRPSQE
SYTTSSN
Sequence cautioni
The sequence X91218 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X91218 Genomic DNA No translation available. CU329672 Genomic DNA Translation: CAB94949.1 |
RefSeqi | NP_587747.1, NM_001022741.2 |
Genome annotation databases
EnsemblFungii | SPCC548.07c.1; SPCC548.07c.1:pep; SPCC548.07c |
GeneIDi | 2538732 |
KEGGi | spo:SPCC548.07c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X91218 Genomic DNA No translation available. CU329672 Genomic DNA Translation: CAB94949.1 |
RefSeqi | NP_587747.1, NM_001022741.2 |
3D structure databases
SMRi | Q9P3U6 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 275316, 6 interactors |
STRINGi | 4896.SPCC548.07c.1 |
Protein family/group databases
TCDBi | 2.A.1.1.112, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | Q9P3U6 |
Genome annotation databases
EnsemblFungii | SPCC548.07c.1; SPCC548.07c.1:pep; SPCC548.07c |
GeneIDi | 2538732 |
KEGGi | spo:SPCC548.07c |
Organism-specific databases
PomBasei | SPCC548.07c, ght1 |
VEuPathDBi | FungiDB:SPCC548.07c |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | Q9P3U6 |
OMAi | IVGCINW |
PhylomeDBi | Q9P3U6 |
Miscellaneous databases
PROi | PR:Q9P3U6 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GHT1_SCHPO | |
Accessioni | Q9P3U6Primary (citable) accession number: Q9P3U6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 11, 2001 |
Last sequence update: | October 1, 2000 | |
Last modified: | February 23, 2022 | |
This is version 140 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families