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Protein

Arginine-glutamic acid dipeptide repeats protein

Gene

RERE

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri507 – 532GATA-typeAdd BLAST26

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, Repressor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine-glutamic acid dipeptide repeats protein
Alternative name(s):
Atrophin-1-like protein
Atrophin-1-related protein
Gene namesi
Name:RERE
Synonyms:ARG, ARP, ATN1L, KIAA0458
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000142599.17
HGNCiHGNC:9965 RERE
MIMi605226 gene
neXtProtiNX_Q9P2R6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Involvement in diseasei

A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24).
Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart (NEDBEH)1 Publication
The disease may be caused by mutations affecting the gene represented in this entry.
Disease descriptionAn autosomal dominant syndrome characterized by developmental delay, intellectual disability, brain anomalies, and neurological abnormalities including seizures, hypotonia, and behavioral problems such as autism spectrum disorders. Brain anomalies include abnormalities and/or thinning of the corpus callosum, diminished white matter volume, abnormal cerebellar vermis, and ventriculomegaly. Congenital defects of the eye, heart and genitourinary system are present in half of the patients.
See also OMIM:616975
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_077007471V → I in NEDBEH; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs765016528Ensembl.1
Natural variantiVAR_0770081156G → R in NEDBEH; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs766951273EnsemblClinVar.1
Natural variantiVAR_0770091262P → R in NEDBEH; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs878853270EnsemblClinVar.1
Natural variantiVAR_0770101431H → Q in NEDBEH; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs869312871EnsemblClinVar.1

Keywords - Diseasei

Disease mutation

Organism-specific databases

DisGeNETi473
MalaCardsiRERE
MIMi616975 phenotype
OpenTargetsiENSG00000142599
Orphaneti1606 1p36 deletion syndrome
494344 RERE-related neurodevelopmental syndrome
PharmGKBiPA34332

Polymorphism and mutation databases

BioMutaiRERE
DMDMi85540730

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000835041 – 1566Arginine-glutamic acid dipeptide repeats proteinAdd BLAST1566

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei53PhosphoserineCombined sources1
Modified residuei56PhosphoserineCombined sources1
Modified residuei120PhosphothreonineCombined sources1
Modified residuei142PhosphoserineBy similarity1
Modified residuei304PhosphoserineCombined sources1
Cross-linki560Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei594PhosphoserineCombined sources1
Modified residuei600PhosphoserineCombined sources1
Modified residuei613PhosphoserineCombined sources1
Cross-linki637Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei642PhosphoserineCombined sources1
Modified residuei656PhosphoserineCombined sources1
Modified residuei675PhosphoserineCombined sources1
Modified residuei679PhosphoserineCombined sources1
Modified residuei1106PhosphoserineCombined sources1
Modified residuei1113PhosphoserineCombined sources1
Modified residuei1115PhosphoserineBy similarity1
Modified residuei1119PhosphothreonineCombined sources1
Modified residuei1158N6-acetyllysineBy similarity1
Modified residuei1259PhosphotyrosineCombined sources1
Modified residuei1266PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9P2R6
MaxQBiQ9P2R6
PaxDbiQ9P2R6
PeptideAtlasiQ9P2R6
PRIDEiQ9P2R6
ProteomicsDBi83883
83884 [Q9P2R6-2]

PTM databases

CarbonylDBiQ9P2R6
iPTMnetiQ9P2R6
PhosphoSitePlusiQ9P2R6

Expressioni

Tissue specificityi

Widely expressed. Expressed in tumor cell lines.3 Publications

Gene expression databases

BgeeiENSG00000142599 Expressed in 239 organ(s), highest expression level in corpus callosum
CleanExiHS_RERE
ExpressionAtlasiQ9P2R6 baseline and differential
GenevisibleiQ9P2R6 HS

Organism-specific databases

HPAiHPA024093

Interactioni

Subunit structurei

Interacts with HDAC1 (By similarity). Interacts with ATN1. Interaction with ATN1 is improved when the poly-Gln region of ATN1 is extended. Interacts with FAT1.By similarity2 Publications

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

BioGridi106963, 32 interactors
DIPiDIP-47606N
IntActiQ9P2R6, 30 interactors
MINTiQ9P2R6
STRINGi9606.ENSP00000338629

Structurei

Secondary structure

11566
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ9P2R6
SMRiQ9P2R6
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9P2R6

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 283BAHPROSITE-ProRule annotationAdd BLAST181
Domaini284 – 387ELM2PROSITE-ProRule annotationAdd BLAST104
Domaini391 – 443SANTPROSITE-ProRule annotationAdd BLAST53

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1156 – 1211Sequence analysisAdd BLAST56

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi738 – 1118Pro-richAdd BLAST381
Compositional biasi1179 – 1204Arg/Glu-rich (mixed charge)Add BLAST26
Compositional biasi1300 – 1322Arg/Glu-rich (mixed charge)Add BLAST23
Compositional biasi1425 – 1445His-richAdd BLAST21
Compositional biasi1451 – 1510Pro-richAdd BLAST60

Domaini

The interaction with ATN1 is mediated by the coiled coil domain.

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri507 – 532GATA-typeAdd BLAST26

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGiKOG2133 Eukaryota
ENOG410ZIND LUCA
GeneTreeiENSGT00580000081398
HOGENOMiHOG000231091
HOVERGENiHBG079774
InParanoidiQ9P2R6
KOiK05628
OMAiQSHKHPP
OrthoDBiEOG091G0O1H
PhylomeDBiQ9P2R6
TreeFamiTF328554

Family and domain databases

CDDicd00202 ZnF_GATA, 1 hit
InterProiView protein in InterPro
IPR002951 Atrophin-like
IPR001025 BAH_dom
IPR000949 ELM2_dom
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb
IPR017884 SANT_dom
IPR000679 Znf_GATA
PfamiView protein in Pfam
PF03154 Atrophin-1, 1 hit
PF01426 BAH, 1 hit
PF01448 ELM2, 1 hit
PF00320 GATA, 1 hit
SMARTiView protein in SMART
SM00439 BAH, 1 hit
SM01189 ELM2, 1 hit
SM00717 SANT, 1 hit
SM00401 ZnF_GATA, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51038 BAH, 1 hit
PS51156 ELM2, 1 hit
PS51293 SANT, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Note: Additional isoforms seem to exist.

This entry has 2 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9P2R6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTADKDKDKD KEKDRDRDRD REREKRDKAR ESENSRPRRS CTLEGGAKNY
60 70 80 90 100
AESDHSEDED NDNNSATAEE STKKNKKKPP KKKSRYERTD TGEITSYITE
110 120 130 140 150
DDVVYRPGDC VYIESRRPNT PYFICSIQDF KLVHNSQACC RSPTPALCDP
160 170 180 190 200
PACSLPVASQ PPQHLSEAGR GPVGSKRDHL LMNVKWYYRQ SEVPDSVYQH
210 220 230 240 250
LVQDRHNEND SGRELVITDP VIKNRELFIS DYVDTYHAAA LRGKCNISHF
260 270 280 290 300
SDIFAAREFK ARVDSFFYIL GYNPETRRLN STQGEIRVGP SHQAKLPDLQ
310 320 330 340 350
PFPSPDGDTV TQHEELVWMP GVNDCDLLMY LRAARSMAAF AGMCDGGSTE
360 370 380 390 400
DGCVAASRDD TTLNALNTLH ESGYDAGKAL QRLVKKPVPK LIEKCWTEDE
410 420 430 440 450
VKRFVKGLRQ YGKNFFRIRK ELLPNKETGE LITFYYYWKK TPEAASSRAH
460 470 480 490 500
RRHRRQAVFR RIKTRTASTP VNTPSRPPSS EFLDLSSASE DDFDSEDSEQ
510 520 530 540 550
ELKGYACRHC FTTTSKDWHH GGRENILLCT DCRIHFKKYG ELPPIEKPVD
560 570 580 590 600
PPPFMFKPVK EEDDGLSGKH SMRTRRSRGS MSTLRSGRKK QPASPDGRTS
610 620 630 640 650
PINEDIRSSG RNSPSAASTS SNDSKAETVK KSAKKVKEEA SSPLKSNKRQ
660 670 680 690 700
REKVASDTEE ADRTSSKKTK TQEISRPNSP SEGEGESSDS RSVNDEGSSD
710 720 730 740 750
PKDIDQDNRS TSPSIPSPQD NESDSDSSAQ QQMLQAQPPA LQAPTGVTPA
760 770 780 790 800
PSSAPPGTPQ LPTPGPTPSA TAVPPQGSPT ASQAPNQPQA PTAPVPHTHI
810 820 830 840 850
QQAPALHPQR PPSPHPPPHP SPHPPLQPLT GSAGQPSAPS HAQPPLHGQG
860 870 880 890 900
PPGPHSLQAG PLLQHPGPPQ PFGLPPQASQ GQAPLGTSPA AAYPHTSLQL
910 920 930 940 950
PASQSALQSQ QPPREQPLPP APLAMPHIKP PPTTPIPQLP APQAHKHPPH
960 970 980 990 1000
LSGPSPFSMN ANLPPPPALK PLSSLSTHHP PSAHPPPLQL MPQSQPLPSS
1010 1020 1030 1040 1050
PAQPPGLTQS QNLPPPPASH PPTGLHQVAP QPPFAQHPFV PGGPPPITPP
1060 1070 1080 1090 1100
TCPSTSTPPA GPGTSAQPPC SGAAASGGSI AGGSSCPLPT VQIKEEALDD
1110 1120 1130 1140 1150
AEEPESPPPP PRSPSPEPTV VDTPSHASQS ARFYKHLDRG YNSCARTDLY
1160 1170 1180 1190 1200
FMPLAGSKLA KKREEAIEKA KREAEQKARE EREREKEKEK ERERERERER
1210 1220 1230 1240 1250
EAERAAKASS SAHEGRLSDP QLSGPGHMRP SFEPPPTTIA AVPPYIGPDT
1260 1270 1280 1290 1300
PALRTLSEYA RPHVMSPTNR NHPFYMPLNP TDPLLAYHMP GLYNVDPTIR
1310 1320 1330 1340 1350
ERELREREIR EREIRERELR ERMKPGFEVK PPELDPLHPA ANPMEHFARH
1360 1370 1380 1390 1400
SALTIPPTAG PHPFASFHPG LNPLERERLA LAGPQLRPEM SYPDRLAAER
1410 1420 1430 1440 1450
IHAERMASLT SDPLARLQMF NVTPHHHQHS HIHSHLHLHQ QDPLHQGSAG
1460 1470 1480 1490 1500
PVHPLVDPLT AGPHLARFPY PPGTLPNPLL GQPPHEHEML RHPVFGTPYP
1510 1520 1530 1540 1550
RDLPGAIPPP MSAAHQLQAM HAQSAELQRL AMEQQWLHGH PHMHGGHLPS
1560
QEDYYSRLKK EGDKQL
Length:1,566
Mass (Da):172,424
Last modified:January 10, 2006 - v2
Checksum:iECA4A22026E3E96F
GO
Isoform 2 (identifier: Q9P2R6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-554: Missing.

Show »
Length:1,012
Mass (Da):109,048
Checksum:i54B60DCBF0FB85FE
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AKN3B1AKN3_HUMAN
Arginine-glutamic acid dipeptide (R...
RERE hCG_2008872
1,298Annotation score:
H7BYW9H7BYW9_HUMAN
Arginine-glutamic acid dipeptide re...
RERE
584Annotation score:
A0A075B770A0A075B770_HUMAN
Arginine-glutamic acid dipeptide re...
RERE
213Annotation score:
H0Y975H0Y975_HUMAN
Arginine-glutamic acid dipeptide re...
RERE
91Annotation score:
D6RA28D6RA28_HUMAN
Arginine-glutamic acid dipeptide re...
RERE
177Annotation score:
K7EIE3K7EIE3_HUMAN
Arginine-glutamic acid dipeptide re...
RERE
89Annotation score:
K7EIQ4K7EIQ4_HUMAN
Arginine-glutamic acid dipeptide re...
RERE
26Annotation score:
K7EJQ1K7EJQ1_HUMAN
Arginine-glutamic acid dipeptide re...
RERE
35Annotation score:

Sequence cautioni

The sequence AAC31120 differs from that shown. Reason: Frameshift at positions 588 and 596.Curated
The sequence AAD27584 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti65S → G in BAA95898 (PubMed:10814707).Curated1
Sequence conflicti68A → T in BAA95898 (PubMed:10814707).Curated1
Sequence conflicti114 – 115ES → VC in BAA95898 (PubMed:10814707).Curated2
Sequence conflicti643P → L in AAC31120 (Ref. 3) Curated1
Sequence conflicti921A → G in BAA95898 (PubMed:10814707).Curated1
Sequence conflicti940P → A in BAA95898 (PubMed:10814707).Curated1
Sequence conflicti957F → L in AAD27584 (PubMed:10729226).Curated1
Sequence conflicti977T → K no nucleotide entry (PubMed:11331249).Curated1
Sequence conflicti984H → N no nucleotide entry (PubMed:11331249).Curated1
Sequence conflicti1009 – 1011QSQ → RTR in AAD27584 (PubMed:10729226).Curated3
Sequence conflicti1117E → D in AAD27584 (PubMed:10729226).Curated1
Sequence conflicti1272H → Q in AAD27584 (PubMed:10729226).Curated1
Sequence conflicti1489 – 1490ML → IV in BAA95898 (PubMed:10814707).Curated2
Sequence conflicti1529R → K in AAD27584 (PubMed:10729226).Curated1
Sequence conflicti1536W → C in AAD27584 (PubMed:10729226).Curated1
Sequence conflicti1543M → R in AAD27584 (PubMed:10729226).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_077007471V → I in NEDBEH; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs765016528Ensembl.1
Natural variantiVAR_0770081156G → R in NEDBEH; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs766951273EnsemblClinVar.1
Natural variantiVAR_0770091262P → R in NEDBEH; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs878853270EnsemblClinVar.1
Natural variantiVAR_0770101431H → Q in NEDBEH; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs869312871EnsemblClinVar.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0168781 – 554Missing in isoform 2. 1 PublicationAdd BLAST554

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB036737 mRNA Translation: BAA95898.1
AF016005 mRNA Translation: AAC31120.1 Frameshift.
AF041104
, AF041096, AF041097, AF041098, AF041099, AF041100, AF041101, AF041102, AF041103 Genomic DNA Translation: AAC28264.1
AL356072 Genomic DNA No translation available.
AL357713 Genomic DNA No translation available.
AL096855 Genomic DNA No translation available.
AB007927 mRNA Translation: BAA32303.3
AF118275 mRNA Translation: AAD27584.1 Different initiation.
CCDSiCCDS41243.1 [Q9P2R6-2]
CCDS95.1 [Q9P2R6-1]
RefSeqiNP_001036146.1, NM_001042681.1 [Q9P2R6-1]
NP_001036147.1, NM_001042682.1 [Q9P2R6-2]
NP_036234.3, NM_012102.3 [Q9P2R6-1]
XP_005263521.1, XM_005263464.2 [Q9P2R6-1]
XP_016856847.1, XM_017001358.1 [Q9P2R6-1]
XP_016856848.1, XM_017001359.1 [Q9P2R6-1]
UniGeneiHs.463041

Genome annotation databases

EnsembliENST00000337907; ENSP00000338629; ENSG00000142599 [Q9P2R6-1]
ENST00000400908; ENSP00000383700; ENSG00000142599 [Q9P2R6-1]
ENST00000476556; ENSP00000422246; ENSG00000142599 [Q9P2R6-2]
GeneIDi473
KEGGihsa:473
UCSCiuc001apd.4 human [Q9P2R6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement, Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB036737 mRNA Translation: BAA95898.1
AF016005 mRNA Translation: AAC31120.1 Frameshift.
AF041104
, AF041096, AF041097, AF041098, AF041099, AF041100, AF041101, AF041102, AF041103 Genomic DNA Translation: AAC28264.1
AL356072 Genomic DNA No translation available.
AL357713 Genomic DNA No translation available.
AL096855 Genomic DNA No translation available.
AB007927 mRNA Translation: BAA32303.3
AF118275 mRNA Translation: AAD27584.1 Different initiation.
CCDSiCCDS41243.1 [Q9P2R6-2]
CCDS95.1 [Q9P2R6-1]
RefSeqiNP_001036146.1, NM_001042681.1 [Q9P2R6-1]
NP_001036147.1, NM_001042682.1 [Q9P2R6-2]
NP_036234.3, NM_012102.3 [Q9P2R6-1]
XP_005263521.1, XM_005263464.2 [Q9P2R6-1]
XP_016856847.1, XM_017001358.1 [Q9P2R6-1]
XP_016856848.1, XM_017001359.1 [Q9P2R6-1]
UniGeneiHs.463041

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2YQKNMR-A392-441[»]
ProteinModelPortaliQ9P2R6
SMRiQ9P2R6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi106963, 32 interactors
DIPiDIP-47606N
IntActiQ9P2R6, 30 interactors
MINTiQ9P2R6
STRINGi9606.ENSP00000338629

PTM databases

CarbonylDBiQ9P2R6
iPTMnetiQ9P2R6
PhosphoSitePlusiQ9P2R6

Polymorphism and mutation databases

BioMutaiRERE
DMDMi85540730

Proteomic databases

EPDiQ9P2R6
MaxQBiQ9P2R6
PaxDbiQ9P2R6
PeptideAtlasiQ9P2R6
PRIDEiQ9P2R6
ProteomicsDBi83883
83884 [Q9P2R6-2]

Protocols and materials databases

DNASUi473
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000337907; ENSP00000338629; ENSG00000142599 [Q9P2R6-1]
ENST00000400908; ENSP00000383700; ENSG00000142599 [Q9P2R6-1]
ENST00000476556; ENSP00000422246; ENSG00000142599 [Q9P2R6-2]
GeneIDi473
KEGGihsa:473
UCSCiuc001apd.4 human [Q9P2R6-1]

Organism-specific databases

CTDi473
DisGeNETi473
EuPathDBiHostDB:ENSG00000142599.17
GeneCardsiRERE
HGNCiHGNC:9965 RERE
HPAiHPA024093
MalaCardsiRERE
MIMi605226 gene
616975 phenotype
neXtProtiNX_Q9P2R6
OpenTargetsiENSG00000142599
Orphaneti1606 1p36 deletion syndrome
494344 RERE-related neurodevelopmental syndrome
PharmGKBiPA34332
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2133 Eukaryota
ENOG410ZIND LUCA
GeneTreeiENSGT00580000081398
HOGENOMiHOG000231091
HOVERGENiHBG079774
InParanoidiQ9P2R6
KOiK05628
OMAiQSHKHPP
OrthoDBiEOG091G0O1H
PhylomeDBiQ9P2R6
TreeFamiTF328554

Miscellaneous databases

ChiTaRSiRERE human
EvolutionaryTraceiQ9P2R6
GeneWikiiRERE
GenomeRNAii473
PROiPR:Q9P2R6
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000142599 Expressed in 239 organ(s), highest expression level in corpus callosum
CleanExiHS_RERE
ExpressionAtlasiQ9P2R6 baseline and differential
GenevisibleiQ9P2R6 HS

Family and domain databases

CDDicd00202 ZnF_GATA, 1 hit
InterProiView protein in InterPro
IPR002951 Atrophin-like
IPR001025 BAH_dom
IPR000949 ELM2_dom
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb
IPR017884 SANT_dom
IPR000679 Znf_GATA
PfamiView protein in Pfam
PF03154 Atrophin-1, 1 hit
PF01426 BAH, 1 hit
PF01448 ELM2, 1 hit
PF00320 GATA, 1 hit
SMARTiView protein in SMART
SM00439 BAH, 1 hit
SM01189 ELM2, 1 hit
SM00717 SANT, 1 hit
SM00401 ZnF_GATA, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51038 BAH, 1 hit
PS51156 ELM2, 1 hit
PS51293 SANT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRERE_HUMAN
AccessioniPrimary (citable) accession number: Q9P2R6
Secondary accession number(s): O43393
, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: November 7, 2018
This is version 169 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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