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Entry version 134 (08 May 2019)
Sequence version 2 (07 Mar 2006)
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Protein

CTTNBP2 N-terminal-like protein

Gene

CTTNBP2NL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CTTNBP2 N-terminal-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CTTNBP2NL
Synonyms:KIAA1433
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25330 CTTNBP2NL

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615100 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9P2B4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55917

Open Targets

More...
OpenTargetsi
ENSG00000143079

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672062

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CTTNBP2NL

Domain mapping of disease mutations (DMDM)

More...
DMDMi
92087169

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002269971 – 639CTTNBP2 N-terminal-like proteinAdd BLAST639

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei284PhosphoserineCombined sources1
Modified residuei285PhosphoserineCombined sources1
Modified residuei481PhosphoserineCombined sources1
Modified residuei488PhosphoserineCombined sources1
Modified residuei523PhosphoserineCombined sources1
Modified residuei527PhosphoserineCombined sources1
Modified residuei560PhosphoserineCombined sources1
Modified residuei563PhosphoserineCombined sources1
Modified residuei568PhosphoserineCombined sources1
Modified residuei570PhosphothreonineCombined sources1
Modified residuei590PhosphothreonineCombined sources1
Modified residuei592PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9P2B4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9P2B4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9P2B4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9P2B4

PeptideAtlas

More...
PeptideAtlasi
Q9P2B4

PRoteomics IDEntifications database

More...
PRIDEi
Q9P2B4

ProteomicsDB human proteome resource

More...
ProteomicsDBi
83766

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9P2B4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9P2B4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000143079 Expressed in 206 organ(s), highest expression level in neocortex

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9P2B4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9P2B4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA007301

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CTTN/cortactin; this interaction may redistribute CTTN to stress fibers (By similarity). May form homomers. May interact with MOB4, PPP2R1A, PPP2CB, STK24, STK25, STK26, STRN4, STRIP1 and STRIP2.By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121000, 47 interactors

Protein interaction database and analysis system

More...
IntActi
Q9P2B4, 37 interactors

Molecular INTeraction database

More...
MINTi
Q9P2B4

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000271277

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9P2B4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili87 – 285Sequence analysisAdd BLAST199

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1103 Eukaryota
ENOG410YR8R LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182852

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112036

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9P2B4

Identification of Orthologs from Complete Genome Data

More...
OMAi
YQAGINQ

Database of Orthologous Groups

More...
OrthoDBi
660559at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9P2B4

TreeFam database of animal gene trees

More...
TreeFami
TF325130

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019131 Cortactin-binding_p2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09727 CortBP2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9P2B4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLEKLSKPE LLTLFSILEG ELEARDLVIE ALKAQHRDTF IEERYGKYNI
60 70 80 90 100
SDPLMALQRD FETLKEKNDG EKQPVCTNPL SILKVVMKQC KNMQERMLSQ
110 120 130 140 150
LAAAESRHRK VILDLEEERQ RHAQDTAEGD DVTYMLEKER ERLTQQLEFE
160 170 180 190 200
KSQVKKFEKE QKKLSSQLEE ERSRHKQLSS MLVLECKKAT NKAAEEGQKA
210 220 230 240 250
GELSLKLEKE KSRVSKLEEE LAAERKRGLQ TEAQVEKQLS EFDIEREQLR
260 270 280 290 300
AKLNREENRT KTLKEEMESL KKIVKDLEAS HQHSSPNEQL KKPVTVSKGT
310 320 330 340 350
ATEPLMLMSV FCQTESFPAE RTHGSNIAKM TNTGLPGPAT PAYSYAKTNG
360 370 380 390 400
HCDPEIQTTR ELTAGNNVEN QVPPREKSVA LAQEKPVENG GCPVGIETPV
410 420 430 440 450
PMPSPLSSSG SSLSPSSTAS SSLTSSPCSS PVLTKRLLGS SASSPGYQSS
460 470 480 490 500
YQVGINQRFH AARHKFQSQA DQDQQASGLQ SPPSRDLSPT LIDNSAAKQL
510 520 530 540 550
ARNTVTQVLS RFTSQQGPIK PVSPNSSPFG TDYRNLANTA NPRGDTSHSP
560 570 580 590 600
TPGKVSSPLS PLSPGIKSPT IPRAERGNPP PIPPKKPGLT PSPSATTPLT
610 620 630
KTHSQAASLT TAEDLASSCS SNTVVANGKD VELLLPTSS
Length:639
Mass (Da):70,158
Last modified:March 7, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i63F1D27C50623564
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AMN7B1AMN7_HUMAN
CTTNBP2 N-terminal-like protein
CTTNBP2NL
271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA92671 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti38D → V in BAG51087 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050925296V → M. Corresponds to variant dbSNP:rs1175640Ensembl.1
Natural variantiVAR_050926409S → G. Corresponds to variant dbSNP:rs12137578Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB037854 mRNA Translation: BAA92671.1 Different initiation.
AK022544 mRNA Translation: BAG51087.1
AL354760 Genomic DNA No translation available.
BC016029 mRNA Translation: AAH16029.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS845.1

NCBI Reference Sequences

More...
RefSeqi
NP_061174.1, NM_018704.2
XP_011540083.1, XM_011541781.2
XP_016857295.1, XM_017001806.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000271277; ENSP00000271277; ENSG00000143079

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55917

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55917

UCSC genome browser

More...
UCSCi
uc001ebx.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB037854 mRNA Translation: BAA92671.1 Different initiation.
AK022544 mRNA Translation: BAG51087.1
AL354760 Genomic DNA No translation available.
BC016029 mRNA Translation: AAH16029.1
CCDSiCCDS845.1
RefSeqiNP_061174.1, NM_018704.2
XP_011540083.1, XM_011541781.2
XP_016857295.1, XM_017001806.1

3D structure databases

SMRiQ9P2B4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121000, 47 interactors
IntActiQ9P2B4, 37 interactors
MINTiQ9P2B4
STRINGi9606.ENSP00000271277

PTM databases

iPTMnetiQ9P2B4
PhosphoSitePlusiQ9P2B4

Polymorphism and mutation databases

BioMutaiCTTNBP2NL
DMDMi92087169

Proteomic databases

EPDiQ9P2B4
jPOSTiQ9P2B4
MaxQBiQ9P2B4
PaxDbiQ9P2B4
PeptideAtlasiQ9P2B4
PRIDEiQ9P2B4
ProteomicsDBi83766

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55917
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000271277; ENSP00000271277; ENSG00000143079
GeneIDi55917
KEGGihsa:55917
UCSCiuc001ebx.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55917
DisGeNETi55917

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CTTNBP2NL
HGNCiHGNC:25330 CTTNBP2NL
HPAiHPA007301
MIMi615100 gene
neXtProtiNX_Q9P2B4
OpenTargetsiENSG00000143079
PharmGKBiPA142672062

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1103 Eukaryota
ENOG410YR8R LUCA
GeneTreeiENSGT00950000182852
HOGENOMiHOG000112036
InParanoidiQ9P2B4
OMAiYQAGINQ
OrthoDBi660559at2759
PhylomeDBiQ9P2B4
TreeFamiTF325130

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CTTNBP2NL human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
CTTNBP2NL

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55917

Protein Ontology

More...
PROi
PR:Q9P2B4

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000143079 Expressed in 206 organ(s), highest expression level in neocortex
ExpressionAtlasiQ9P2B4 baseline and differential
GenevisibleiQ9P2B4 HS

Family and domain databases

InterProiView protein in InterPro
IPR019131 Cortactin-binding_p2_N
PfamiView protein in Pfam
PF09727 CortBP2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCT2NL_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9P2B4
Secondary accession number(s): B3KMS5, Q96B40
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: March 7, 2006
Last modified: May 8, 2019
This is version 134 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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