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Protein

BAH and coiled-coil domain-containing protein 1

Gene

BAHCC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
BAH and coiled-coil domain-containing protein 1Curated
Alternative name(s):
Bromo adjacent homology domain-containing protein 2
Short name:
BAH domain-containing protein 2
Gene namesi
Name:BAHCC1Imported
Synonyms:BAHD2, KIAA14471 Publication
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000266074.8
HGNCiHGNC:29279 BAHCC1
MIMi617646 gene
neXtProtiNX_Q9P281

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000266074
PharmGKBiPA128394719

Polymorphism and mutation databases

BioMutaiBAHCC1
DMDMi205371795

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003121181 – 2639BAH and coiled-coil domain-containing protein 1Add BLAST2639

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei222N6-acetyllysineCombined sources1
Modified residuei2274PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9P281
PaxDbiQ9P281
PeptideAtlasiQ9P281
PRIDEiQ9P281
ProteomicsDBi83747

PTM databases

iPTMnetiQ9P281
PhosphoSitePlusiQ9P281

Expressioni

Gene expression databases

BgeeiENSG00000266074 Expressed in 133 organ(s), highest expression level in right hemisphere of cerebellum
CleanExiHS_BAHCC1

Organism-specific databases

HPAiHPA023386
HPA076910

Interactioni

Protein-protein interaction databases

BioGridi121648, 12 interactors
IntActiQ9P281, 5 interactors
STRINGi9606.ENSP00000303486

Structurei

3D structure databases

ProteinModelPortaliQ9P281
SMRiQ9P281
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2513 – 2633BAHPROSITE-ProRule annotationAdd BLAST121

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1439 – 1473Sequence analysisAdd BLAST35

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi24 – 41Ala-richPROSITE-ProRule annotationAdd BLAST18
Compositional biasi1858 – 1886Glu-richPROSITE-ProRule annotationAdd BLAST29
Compositional biasi2346 – 2380Ser-richPROSITE-ProRule annotationAdd BLAST35

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IUIU Eukaryota
ENOG410ZM6U LUCA
GeneTreeiENSGT00530000063602
HOGENOMiHOG000095172
HOVERGENiHBG107492
InParanoidiQ9P281
OMAiLPMSHLD
OrthoDBiEOG091G0071
PhylomeDBiQ9P281

Family and domain databases

InterProiView protein in InterPro
IPR001025 BAH_dom
PfamiView protein in Pfam
PF01426 BAH, 1 hit
SMARTiView protein in SMART
SM00439 BAH, 1 hit
PROSITEiView protein in PROSITE
PS51038 BAH, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

Q9P281-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGRDFAPPP HLLSERGSLG HRSAAAAARL APAGPAAQPP AHFQPGKYFP
60 70 80 90 100
SPLPMASHTA SSRLMGSSPA SSFMGSFLTS SLGSAASTHP SGPSSSPPEQ
110 120 130 140 150
AYRGSHPTTS QIWFSHSHEA PGYPRFSGSL ASTFLPVSHL DHHGNSNVLY
160 170 180 190 200
GQHRFYGTQK DNFYLRNLPP QPTLLPANHN FPSVARAAPA HPMGSCSRDR
210 220 230 240 250
DRGEAGSLQK GPKDFDRFLV GKELGREKAG KAAEGKERPA AEEDGGKERH
260 270 280 290 300
KLVLPVPADG HCREGGPAPR GACEGRPKHL TSCLLNTKVL NGEMGRAALA
310 320 330 340 350
SCAGGMLGRP GTGVVTSGRC AKEAAGPPEP GPAFSECLER RQMLHHTASY
360 370 380 390 400
AGPPPPLSTA AGSFPCLQLH GGPDGLCPLQ DKAPRDLKAS GPTFVPSVGH
410 420 430 440 450
LADKGRPFQA AEACAVAGEG KDRHLEGTMA PDHAAPYGVS YAHLKAEGKG
460 470 480 490 500
ERRPGGFEAA LNPRLKGLDY LSSAGPEASF PGLPKSGLDK SGYFELPTSS
510 520 530 540 550
QDCARPGHQD PLGGKAPQAC CTLDKTVGKE APAGPPGAQK VARIRHQQHL
560 570 580 590 600
MAAEVEQGGI GAEAKRKSLE LASLGYSGPH LPPWGVQAGQ GTAMAISEER
610 620 630 640 650
KAGAYLDPFG SGLQQAALLP QELPAPPDEV SAMKNLLKYS SQALVVGQKA
660 670 680 690 700
PLVGLGGLKA SCIQQEAKFL SSKGPGQSER PDCARSREHD TTHGDGEVRQ
710 720 730 740 750
PPVGIAVALA RQKDTVSRSE AAYGTNTARQ GRAAPAFKGG GGPRSTHALD
760 770 780 790 800
LEAEEERTRL CDDRLGLASR ELLLQDSKDR VEFARIHPPS SCPGDLAPHL
810 820 830 840 850
MMQSGQLGGD PAPHTHPHPP WLPRTRSPSL WMGGHSYGLG HPALHQNLPP
860 870 880 890 900
GFPASVAGPV PSVFPLPQDA PTQLVILPSE PTPHSAPHAL ADVMDQASLW
910 920 930 940 950
PPMYGGRGPA SHMQHPGQLP VYSRPQLLRQ QELYALQQQR AAQFQRKPED
960 970 980 990 1000
QHLDLEEPAQ EKAPKSTHKP VALTPTAPGA PSPAAGPTKL PPCCHPPDPK
1010 1020 1030 1040 1050
PPASSPTPPP RPSAPCTLNV CPASSPGPGS RVRSAEEKNG EGQQSTADII
1060 1070 1080 1090 1100
TSEPVARAHS VAHAGLEFLA SNDPSTSASQ SFGITDLPPG YLRPMAGLGF
1110 1120 1130 1140 1150
SLPSDVHSSN LEDPETMQTT APGAQPEPTR TFLPGEPPPC SPRSLEEPGL
1160 1170 1180 1190 1200
LSGAREATQD LAATPYPTER GPQGKAADPS PLEGLQELQC AALLEAGGPE
1210 1220 1230 1240 1250
ATGQAHSTQG GAREERSREE GEQGPSSGAS SQVLEQRAGS PGALEDEGEQ
1260 1270 1280 1290 1300
PAPEEDELEE DELGQQSMED SEEDCGGAPD NSHPPRALPG LDALVAATIN
1310 1320 1330 1340 1350
LGDLPSDSPP DPQPPAASGP PSTVPLPHSS GIHGIALLSE LADLAIQRQR
1360 1370 1380 1390 1400
SERTVPEEEE DVLAFNLQHL ATLATAWSLV EAAGLDSSTA PAQPPTANPC
1410 1420 1430 1440 1450
SGPRLTPRMQ ILQRKDTWTP KTKPVCPLKA AIDRLDTQEV GMRVRLAELQ
1460 1470 1480 1490 1500
RRYKEKQREL ARLQRKHDHE RDESSRSPAR RGPGRPRKRK HSSSLPAPRP
1510 1520 1530 1540 1550
TGPLPRSDGK KVKAVRTSLG LLCAELRGGS GGEPAKKRSK LERSVYAGLQ
1560 1570 1580 1590 1600
TASVEKAQCK KSSCQGGLAP SVAHRVAQLK PKVKSKGLPT GLSSFQQKEA
1610 1620 1630 1640 1650
TPGGRIREKL SRAKSAKVSG ATRHPQPKGH GSRETPRCPA QPSVAASQEA
1660 1670 1680 1690 1700
GSGYDSEDCE GLLGTEAPPR EAGLLLHTGA SVAVLGPSPS SVVKMEANQK
1710 1720 1730 1740 1750
AKKKKERQGL LGACRLSSPE SEVKIKRRSV KAKVGTTLER APGQRPPGAL
1760 1770 1780 1790 1800
GKKKAKGKAK GSLRAEPGAT PSRDALFNPS RAFACREEGS QLASERLKRA
1810 1820 1830 1840 1850
TRKGTVLQPV LRRKNGALSI TLATRNAKAI LGKGRKLSKV KHKAGKQGKG
1860 1870 1880 1890 1900
RAVSRLLESF AVEEDFEFDD NSSFSEEEED EEEEEEDSGP LSAEQSAALA
1910 1920 1930 1940 1950
RSCAIHKEDL RDGLPVLIPK EDSLLYAGSV RTLQPPDIYS IVIEGERGNR
1960 1970 1980 1990 2000
QRIYSLEQLL QEAVLDVRPQ SSRYLPPGTR VCAYWSQKSR CLYPGNVVRG
2010 2020 2030 2040 2050
ASGDEDEDLD SVVVEFDDGD TGHIAVSNVR LLPPDFKIQC TEPSPALLVS
2060 2070 2080 2090 2100
SSCRRTKKVS SEAPPPSEAA TPSLSPKAQD GPEALKTPGK KSISKDKAGK
2110 2120 2130 2140 2150
AELLTSGAKS PTGASDHFLG RRGSPLLSWS AVAQTKRKAV AAASKGPGVL
2160 2170 2180 2190 2200
QNLFQLNGSS KKLRAREALF PVHSVATPIF GNGFRADSFS SLASSYAPFV
2210 2220 2230 2240 2250
GGTGPGLPRG AHKLLRAKKA ERVEAEKGGR RRAGGEFLVK LDHEGVTSPK
2260 2270 2280 2290 2300
NKTCKALLMG DKDFSPKLGR PLPSPSYVHP ALVGKDKKGR APIPPLPMGL
2310 2320 2330 2340 2350
ALRKYAGQAE FPLPYDSDCH SSFSDEDEDG PGLAAGVPSR FLARLSVSSS
2360 2370 2380 2390 2400
SSGSSTSSSS GSVSTSSLCS SDNEDSSYSS DDEDPALLLQ TCLTHPVPTL
2410 2420 2430 2440 2450
LAQPEALRSK GSGPHAHAQR CFLSRATVAG TGAGSGPSSS SKSKLKRKEA
2460 2470 2480 2490 2500
LSFSKAKELS RRQRPPSVEN RPKISAFLPA RQLWKWSGNP TQRRGMKGKA
2510 2520 2530 2540 2550
RKLFYKAIVR GEETLRVGDC AVFLSAGRPN LPYIGRIESM WESWGSNMVV
2560 2570 2580 2590 2600
KVKWFYHPEE TKLGKRQCDG KNALYQSCHE DENDVQTISH KCQVVAREQY
2610 2620 2630
EQMARSRKCQ DRQDLYYLAG TYDPTTGRLV TADGVPILC
Length:2,639
Mass (Da):280,016
Last modified:March 28, 2018 - v4
Checksum:i3A21114C7ACF1D9D
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WBW8F8WBW8_HUMAN
BAH and coiled-coil domain-containi...
BAHCC1
2,608Annotation score:

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_061559272A → T. Corresponds to variant dbSNP:rs12952981Ensembl.1
Natural variantiVAR_0595891168T → A1 PublicationCorresponds to variant dbSNP:rs7213444Ensembl.1
Natural variantiVAR_0615601434R → Q. Corresponds to variant dbSNP:rs35572189Ensembl.1
Natural variantiVAR_0615611678T → A1 PublicationCorresponds to variant dbSNP:rs12601317Ensembl.1
Natural variantiVAR_0615622029V → I. Corresponds to variant dbSNP:rs34680524Ensembl.1
Natural variantiVAR_0506852510R → C. Corresponds to variant dbSNP:rs8746Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110285 Genomic DNA No translation available.
AC139149 Genomic DNA No translation available.
AC213194 Genomic DNA No translation available.
AADB02019016 Genomic DNA No translation available.
AB040880 mRNA Translation: BAA95971.1
BC033222 mRNA Translation: AAH33222.1
CCDSiCCDS74173.1
RefSeqiNP_001278253.1, NM_001291324.1
UniGeneiHs.514580

Genome annotation databases

EnsembliENST00000584436; ENSP00000462154; ENSG00000266074
GeneIDi57597
KEGGihsa:57597

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110285 Genomic DNA No translation available.
AC139149 Genomic DNA No translation available.
AC213194 Genomic DNA No translation available.
AADB02019016 Genomic DNA No translation available.
AB040880 mRNA Translation: BAA95971.1
BC033222 mRNA Translation: AAH33222.1
CCDSiCCDS74173.1
RefSeqiNP_001278253.1, NM_001291324.1
UniGeneiHs.514580

3D structure databases

ProteinModelPortaliQ9P281
SMRiQ9P281
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121648, 12 interactors
IntActiQ9P281, 5 interactors
STRINGi9606.ENSP00000303486

PTM databases

iPTMnetiQ9P281
PhosphoSitePlusiQ9P281

Polymorphism and mutation databases

BioMutaiBAHCC1
DMDMi205371795

Proteomic databases

EPDiQ9P281
PaxDbiQ9P281
PeptideAtlasiQ9P281
PRIDEiQ9P281
ProteomicsDBi83747

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000584436; ENSP00000462154; ENSG00000266074
GeneIDi57597
KEGGihsa:57597

Organism-specific databases

CTDi57597
EuPathDBiHostDB:ENSG00000266074.8
GeneCardsiBAHCC1
H-InvDBiHIX0014249
HGNCiHGNC:29279 BAHCC1
HPAiHPA023386
HPA076910
MIMi617646 gene
neXtProtiNX_Q9P281
OpenTargetsiENSG00000266074
PharmGKBiPA128394719
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IUIU Eukaryota
ENOG410ZM6U LUCA
GeneTreeiENSGT00530000063602
HOGENOMiHOG000095172
HOVERGENiHBG107492
InParanoidiQ9P281
OMAiLPMSHLD
OrthoDBiEOG091G0071
PhylomeDBiQ9P281

Miscellaneous databases

ChiTaRSiBAHCC1 human
GenomeRNAii57597
PROiPR:Q9P281
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000266074 Expressed in 133 organ(s), highest expression level in right hemisphere of cerebellum
CleanExiHS_BAHCC1

Family and domain databases

InterProiView protein in InterPro
IPR001025 BAH_dom
PfamiView protein in Pfam
PF01426 BAH, 1 hit
SMARTiView protein in SMART
SM00439 BAH, 1 hit
PROSITEiView protein in PROSITE
PS51038 BAH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiBAHC1_HUMAN
AccessioniPrimary (citable) accession number: Q9P281
Secondary accession number(s): A0A075B747, Q5U629
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: March 28, 2018
Last modified: September 12, 2018
This is version 104 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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