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Entry version 128 (07 Apr 2021)
Sequence version 3 (24 Nov 2009)
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Protein

Probable tRNA methyltransferase 9B

Gene

TRMT9B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May modifie wobble uridines in specific arginine and glutamic acid tRNAs. Acts as a tumor suppressor by promoting the expression of LIN9.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processtRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9P272

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6782315, tRNA modification in the nucleus and cytosol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable tRNA methyltransferase 9BCurated
Alternative name(s):
Probable tRNA methyltransferase 9-like protein1 Publication (EC:2.1.1.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TRMT9BImported
Synonyms:C8orf79, KIAA1456, TRM9L1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26725, TRMT9B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615666, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9P272

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000250305.8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
57604

Open Targets

More...
OpenTargetsi
ENSG00000250305

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485343

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9P272, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KIAA1456

Domain mapping of disease mutations (DMDM)

More...
DMDMi
269849677

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003287921 – 454Probable tRNA methyltransferase 9BAdd BLAST454

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei214PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9P272

PeptideAtlas

More...
PeptideAtlasi
Q9P272

PRoteomics IDEntifications database

More...
PRIDEi
Q9P272

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72551
83741 [Q9P272-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9P272

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9P272

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Down-regulated in breast, bladder, colorectal, cervix and testicular carcinomas.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000250305, Expressed in cerebellar vermis and 192 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9P272, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9P272, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000250305, Group enriched (brain, thyroid gland)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
121652, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q9P272, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000432695

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9P272, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the methyltransferase superfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1331, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160373

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_029501_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9P272

Identification of Orthologs from Complete Genome Data

More...
OMAi
FREGELY

Database of Orthologous Groups

More...
OrthoDBi
996085at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9P272

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013216, Methyltransf_11
IPR029063, SAM-dependent_MTases
IPR032873, Trm9

The PANTHER Classification System

More...
PANTHERi
PTHR13069:SF21, PTHR13069:SF21, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08241, Methyltransf_11, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53335, SSF53335, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9P272-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDHEAAQLEK QHVHNVYEST APYFSDLQSK AWPRVRQFLQ EQKPGSLIAD
60 70 80 90 100
IGCGTGKYLK VNSQVHTVGC DYCGPLVEIA RNRGCEAMVC DNLNLPFRDE
110 120 130 140 150
GFDAIISIGV IHHFSTKQRR IRAIKEMARV LVPGGQLMIY VWAMEQKNRH
160 170 180 190 200
FEKQDVLVPW NRALCSQLFS ESSQSGRKRQ CGYPERGHPY HPPCSECSCS
210 220 230 240 250
VCFKEQCGSK RSHSVGYEPA MARTCFANIS KEGEEEYGFY STLGKSFRSW
260 270 280 290 300
FFSRSLDEST LRKQIERVRP LKNTEVWASS TVTVQPSRHS SLDFDHQEPF
310 320 330 340 350
STKGQSLDEE VFVESSSGKH LEWLRAPGTL KHLNGDHQGE MRRNGGGNFL
360 370 380 390 400
DSTNTGVNCV DAGNIEDDNP SASKILRRIS AVDSTDFNPD DTMSVEDPQT
410 420 430 440 450
DVLDSTAFMR YYHVFREGEL CSLLKENVSE LRILSSGNDH GNWCIIAEKK

RGCD
Length:454
Mass (Da):51,299
Last modified:November 24, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i72074CFF852A0331
GO
Isoform 2 (identifier: Q9P272-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     53-60: CGTGKYLK → NQAASSLT
     61-454: Missing.

Show »
Length:60
Mass (Da):6,768
Checksum:i4E1F72443EB7A233
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6XBY7F6XBY7_HUMAN
Probable tRNA methyltransferase 9B
TRMT9B
196Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PK20E9PK20_HUMAN
Probable tRNA methyltransferase 9B
TRMT9B
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC04326 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_07783293L → F Found in a child with sporadic epilepsy; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs757023992Ensembl.1
Natural variantiVAR_061378150H → R2 PublicationsCorresponds to variant dbSNP:rs528255Ensembl.1
Natural variantiVAR_061379207C → G2 PublicationsCorresponds to variant dbSNP:rs3739310Ensembl.1
Natural variantiVAR_056243219P → T. Corresponds to variant dbSNP:rs505480Ensembl.1
Natural variantiVAR_056244265I → T. Corresponds to variant dbSNP:rs3739308Ensembl.1
Natural variantiVAR_061380304G → E2 PublicationsCorresponds to variant dbSNP:rs502882Ensembl.1
Natural variantiVAR_056245337H → L. Corresponds to variant dbSNP:rs34995506Ensembl.1
Natural variantiVAR_061381451R → G2 PublicationsCorresponds to variant dbSNP:rs608052Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05937853 – 60CGTGKYLK → NQAASSLT in isoform 2. 8
Alternative sequenceiVSP_05937961 – 454Missing in isoform 2. Add BLAST394

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC135352 Genomic DNA No translation available.
AB040889 mRNA Translation: BAA95980.1
BC035082 mRNA No translation available.
AK094299 mRNA Translation: BAC04326.1 Sequence problems.
BC016633 mRNA Translation: AAH16633.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47808.1 [Q9P272-1]

NCBI Reference Sequences

More...
RefSeqi
NP_065895.2, NM_020844.2 [Q9P272-1]
XP_005273643.1, XM_005273586.4 [Q9P272-1]
XP_016869194.1, XM_017013705.1 [Q9P272-1]
XP_016869195.1, XM_017013706.1 [Q9P272-1]
XP_016869196.1, XM_017013707.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000400069; ENSP00000468715; ENSG00000250305 [Q9P272-3]
ENST00000524591; ENSP00000432695; ENSG00000250305 [Q9P272-1]
ENST00000528753; ENSP00000466330; ENSG00000250305 [Q9P272-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57604

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57604

UCSC genome browser

More...
UCSCi
uc010lsq.4, human [Q9P272-1]
uc064kkg.1, human

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135352 Genomic DNA No translation available.
AB040889 mRNA Translation: BAA95980.1
BC035082 mRNA No translation available.
AK094299 mRNA Translation: BAC04326.1 Sequence problems.
BC016633 mRNA Translation: AAH16633.2
CCDSiCCDS47808.1 [Q9P272-1]
RefSeqiNP_065895.2, NM_020844.2 [Q9P272-1]
XP_005273643.1, XM_005273586.4 [Q9P272-1]
XP_016869194.1, XM_017013705.1 [Q9P272-1]
XP_016869195.1, XM_017013706.1 [Q9P272-1]
XP_016869196.1, XM_017013707.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi121652, 5 interactors
IntActiQ9P272, 2 interactors
STRINGi9606.ENSP00000432695

PTM databases

iPTMnetiQ9P272
PhosphoSitePlusiQ9P272

Genetic variation databases

BioMutaiKIAA1456
DMDMi269849677

Proteomic databases

PaxDbiQ9P272
PeptideAtlasiQ9P272
PRIDEiQ9P272
ProteomicsDBi72551
83741 [Q9P272-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
58596, 59 antibodies

The DNASU plasmid repository

More...
DNASUi
57604

Genome annotation databases

EnsembliENST00000400069; ENSP00000468715; ENSG00000250305 [Q9P272-3]
ENST00000524591; ENSP00000432695; ENSG00000250305 [Q9P272-1]
ENST00000528753; ENSP00000466330; ENSG00000250305 [Q9P272-3]
GeneIDi57604
KEGGihsa:57604
UCSCiuc010lsq.4, human [Q9P272-1]
uc064kkg.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57604
DisGeNETi57604

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TRMT9B
HGNCiHGNC:26725, TRMT9B
HPAiENSG00000250305, Group enriched (brain, thyroid gland)
MIMi615666, gene
neXtProtiNX_Q9P272
OpenTargetsiENSG00000250305
PharmGKBiPA143485343
VEuPathDBiHostDB:ENSG00000250305.8

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1331, Eukaryota
GeneTreeiENSGT00940000160373
HOGENOMiCLU_029501_0_1_1
InParanoidiQ9P272
OMAiFREGELY
OrthoDBi996085at2759
PhylomeDBiQ9P272

Enzyme and pathway databases

PathwayCommonsiQ9P272
ReactomeiR-HSA-6782315, tRNA modification in the nucleus and cytosol

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
57604, 7 hits in 982 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57604
PharosiQ9P272, Tdark

Protein Ontology

More...
PROi
PR:Q9P272
RNActiQ9P272, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000250305, Expressed in cerebellar vermis and 192 other tissues
ExpressionAtlasiQ9P272, baseline and differential
GenevisibleiQ9P272, HS

Family and domain databases

InterProiView protein in InterPro
IPR013216, Methyltransf_11
IPR029063, SAM-dependent_MTases
IPR032873, Trm9
PANTHERiPTHR13069:SF21, PTHR13069:SF21, 1 hit
PfamiView protein in Pfam
PF08241, Methyltransf_11, 1 hit
SUPFAMiSSF53335, SSF53335, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTRM9B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9P272
Secondary accession number(s): K7EM26, Q8N9K7, Q96AW6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: November 24, 2009
Last modified: April 7, 2021
This is version 128 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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