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Protein

SLAIN motif-containing protein 2

Gene

SLAIN2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei581Important for interaction with CLIP11

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • cytoplasmic microtubule organization Source: UniProtKB
  • microtubule nucleation Source: UniProtKB
  • positive regulation of microtubule polymerization Source: UniProtKB

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SLAIN motif-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLAIN2
Synonyms:KIAA1458
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000109171.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29282 SLAIN2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610492 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9P270

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi581Missing : Abolishes interaction with CLIP1. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
57606

Open Targets

More...
OpenTargetsi
ENSG00000109171

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162403457

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLAIN2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
166977679

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003169651 – 581SLAIN motif-containing protein 2Add BLAST581

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei43PhosphoserineCombined sources1
Modified residuei48PhosphoserineCombined sources1
Modified residuei63PhosphoserineCombined sources1
Modified residuei88PhosphoserineBy similarity1
Modified residuei134PhosphoserineCombined sources1
Modified residuei147PhosphoserineCombined sources1
Modified residuei160PhosphoserineCombined sources1
Modified residuei179PhosphoserineCombined sources1
Modified residuei247PhosphoserineCombined sources1
Modified residuei250PhosphoserineCombined sources1
Modified residuei251PhosphoserineCombined sources1
Modified residuei254PhosphoserineCombined sources1
Modified residuei315PhosphoserineCombined sources1
Modified residuei323PhosphoserineCombined sources1
Modified residuei377PhosphoserineCombined sources1
Modified residuei391PhosphoserineCombined sources1
Modified residuei413PhosphoserineCombined sources1
Modified residuei433PhosphoserineCombined sources1
Modified residuei456PhosphoserineCombined sources1
Modified residuei462PhosphoserineCombined sources1
Modified residuei467PhosphoserineCombined sources1
Modified residuei538Omega-N-methylarginineBy similarity1
Modified residuei551Omega-N-methylarginineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Is highly phosphorylated during mitosis, but not during interphase. The highly phosphorylated form does not localize at microtubule plus ends and does not interact with MAPRE1 or CKAP5.1 Publication

Keywords - PTMi

Acetylation, Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9P270

MaxQB - The MaxQuant DataBase

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MaxQBi
Q9P270

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9P270

PeptideAtlas

More...
PeptideAtlasi
Q9P270

PRoteomics IDEntifications database

More...
PRIDEi
Q9P270

ProteomicsDB human proteome resource

More...
ProteomicsDBi
83740

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9P270

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q9P270

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000109171 Expressed in 206 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

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CleanExi
HS_SLAIN2

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9P270 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q9P270 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035824
HPA063599

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CLIP1, CLIP2, CKAP5, CLASP1, MAPRE1 and MAPRE3.1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
CKAP5Q140084EBI-3959887,EBI-310585

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121654, 52 interactors

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
Q9P270

Protein interaction database and analysis system

More...
IntActi
Q9P270, 48 interactors

Molecular INTeraction database

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MINTi
Q9P270

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000264313

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1581
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q9P270

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9P270

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili4 – 391 PublicationAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi124 – 128Poly-Glu5

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminus forms a two-stranded coiled coil.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SLAIN motif-containing family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IF0R Eukaryota
ENOG410XPVV LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017860

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000057277

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG072961

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9P270

KEGG Orthology (KO)

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KOi
K16580

Identification of Orthologs from Complete Genome Data

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OMAi
PARSIEY

Database of Orthologous Groups

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OrthoDBi
EOG091G057F

Database for complete collections of gene phylogenies

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PhylomeDBi
Q9P270

TreeFam database of animal gene trees

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TreeFami
TF331616

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR026179 Slain

The PANTHER Classification System

More...
PANTHERi
PTHR22406 PTHR22406, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15301 SLAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9P270-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEDVNSNVNA DQEVRKLQEL VKKLEKQNEQ LRSRSGAVQG AGSLGPGSPV
60 70 80 90 100
RAGASIPSSG AASPRGFPLG LSAKSGGGPG SGPRRTSSEE LRDATSLLAA
110 120 130 140 150
GEGGLLDEVE PLRPDELERL SGWEEEEESW LYSSPKKKLT PMQKSVSPLV
160 170 180 190 200
WCRQVLDYPS PDVECAKKSL IHKLDQTMSA LKRQNLYNNP FNSMSYTSPY
210 220 230 240 250
SPNASSPYSS GFNSPSSTPV RPPIVKQLIL PGNSGNLKSS DRNPPLSPQS
260 270 280 290 300
SIDSELSASE LDEDSIGSNY KLNDVTDVQI LARMQEESLR QEYAATTSRR
310 320 330 340 350
SSGSSCNSTR RGTFSDQELD AQSLDDEDDN MHHAVYPAVN RFSPSPRNSP
360 370 380 390 400
RPSPKQSPRN SPRSRSPARG IEYSRVSPQP MISRLQQPRL SLQGHPTDLQ
410 420 430 440 450
TSNVKNEEKL RRSLPNLSRT SNTQVDSVKS SRSDSNFQVP NGGIPRMQPQ
460 470 480 490 500
ASAIPSPGKF RSPAAPSPLA LRQPVKAFSN HGSGSPGSQE ITQLTQTTSS
510 520 530 540 550
PGPPMVQSTV SANPPSNINS ATLTRPAGTT AMRSGLPRPS APSAGGIPVP
560 570 580
RSKLAQPVRR SLPAPKTYGS MKDDSWKDGC Y
Length:581
Mass (Da):62,543
Last modified:February 5, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44B10B1BBD555B26
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RIF6D6RIF6_HUMAN
SLAIN motif-containing protein 2
SLAIN2
414Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y9L2H0Y9L2_HUMAN
SLAIN motif-containing protein 2
SLAIN2
169Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6REM5D6REM5_HUMAN
SLAIN motif-containing protein 2
SLAIN2
58Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH31691 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAA95982 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti233N → D in BAF83695 (PubMed:14702039).Curated1
Sequence conflicti558V → A in BAF83695 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB040891 mRNA Translation: BAA95982.1 Different initiation.
AK291006 mRNA Translation: BAF83695.1
BC031691 mRNA Translation: AAH31691.2 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47051.1

NCBI Reference Sequences

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RefSeqi
NP_065897.1, NM_020846.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.479677

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000264313; ENSP00000264313; ENSG00000109171

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57606

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57606

UCSC genome browser

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UCSCi
uc003gya.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB040891 mRNA Translation: BAA95982.1 Different initiation.
AK291006 mRNA Translation: BAF83695.1
BC031691 mRNA Translation: AAH31691.2 Different initiation.
CCDSiCCDS47051.1
RefSeqiNP_065897.1, NM_020846.1
UniGeneiHs.479677

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RDVX-ray1.75E/F/G/H574-581[»]
ProteinModelPortaliQ9P270
SMRiQ9P270
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121654, 52 interactors
ELMiQ9P270
IntActiQ9P270, 48 interactors
MINTiQ9P270
STRINGi9606.ENSP00000264313

PTM databases

iPTMnetiQ9P270
PhosphoSitePlusiQ9P270

Polymorphism and mutation databases

BioMutaiSLAIN2
DMDMi166977679

Proteomic databases

EPDiQ9P270
MaxQBiQ9P270
PaxDbiQ9P270
PeptideAtlasiQ9P270
PRIDEiQ9P270
ProteomicsDBi83740

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000264313; ENSP00000264313; ENSG00000109171
GeneIDi57606
KEGGihsa:57606
UCSCiuc003gya.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57606
DisGeNETi57606
EuPathDBiHostDB:ENSG00000109171.14

GeneCards: human genes, protein and diseases

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GeneCardsi
SLAIN2

H-Invitational Database, human transcriptome db

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H-InvDBi
HIX0012487
HGNCiHGNC:29282 SLAIN2
HPAiHPA035824
HPA063599
MIMi610492 gene
neXtProtiNX_Q9P270
OpenTargetsiENSG00000109171
PharmGKBiPA162403457

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IF0R Eukaryota
ENOG410XPVV LUCA
GeneTreeiENSGT00390000017860
HOGENOMiHOG000057277
HOVERGENiHBG072961
InParanoidiQ9P270
KOiK16580
OMAiPARSIEY
OrthoDBiEOG091G057F
PhylomeDBiQ9P270
TreeFamiTF331616

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SLAIN2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
57606

Protein Ontology

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PROi
PR:Q9P270

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000109171 Expressed in 206 organ(s), highest expression level in testis
CleanExiHS_SLAIN2
ExpressionAtlasiQ9P270 baseline and differential
GenevisibleiQ9P270 HS

Family and domain databases

InterProiView protein in InterPro
IPR026179 Slain
PANTHERiPTHR22406 PTHR22406, 1 hit
PfamiView protein in Pfam
PF15301 SLAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSLAI2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9P270
Secondary accession number(s): A8K4P1, Q8N5R3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 7, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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