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Entry version 124 (07 Apr 2021)
Sequence version 3 (15 Jan 2008)
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Protein

Junctional protein associated with coronary artery disease

Gene

JCAD

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9P266

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Junctional protein associated with coronary artery disease
Short name:
JCAD
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:JCADImported
Synonyms:KIAA14621 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29283, JCAD

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614398, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9P266

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000165757.8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell junction

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
57608

Open Targets

More...
OpenTargetsi
ENSG00000165757

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134955526

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9P266, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
JCAD

Domain mapping of disease mutations (DMDM)

More...
DMDMi
166218835

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003141851 – 1359Junctional protein associated with coronary artery diseaseAdd BLAST1359

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1044PhosphoserineCombined sources1
Modified residuei1050PhosphoserineBy similarity1
Modified residuei1194PhosphoserineCombined sources1
Modified residuei1281PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9P266

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9P266

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9P266

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9P266

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9P266

PeptideAtlas

More...
PeptideAtlasi
Q9P266

PRoteomics IDEntifications database

More...
PRIDEi
Q9P266

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83737

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9P266

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9P266

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000165757, Expressed in amniotic fluid and 230 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9P266, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000165757, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
121655, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q9P266, 4 interactors

Molecular INTeraction database

More...
MINTi
Q9P266

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000364526

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9P266, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi247 – 413Pro-richAdd BLAST167
Compositional biasi844 – 847Poly-Glu4
Compositional biasi848 – 862Ser-richAdd BLAST15

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QURJ, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015348

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005347_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9P266

Identification of Orthologs from Complete Genome Data

More...
OMAi
GGAPFCS

Database of Orthologous Groups

More...
OrthoDBi
208373at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9P266

TreeFam database of animal gene trees

More...
TreeFami
TF335913

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028221, JCAD

The PANTHER Classification System

More...
PANTHERi
PTHR34757, PTHR34757, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15351, JCAD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9P266-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYSVEDLLIS HGYKLSRDPP ASREDNPKGR QAARTGTRAG QGLQNGHEDG
60 70 80 90 100
PAALAHRKTS AGKGHVSDSE SRRSTPRGHG EPQSTSASRT SEAGFCNQPP
110 120 130 140 150
SAWSSHPPTG NDQAYRRRGR QEARSQKPRE HENLEARGMA QAHSLPVHVR
160 170 180 190 200
EGPWEVGGRS EHVMKKPVWE EELRMSGPAK WQNVSLESWN QPRKLGRQMS
210 220 230 240 250
DGDGERLFQD LYPFIQGEHV LNSQNKGKSR SLPRVLSPES LSCTEIPIPL
260 270 280 290 300
NERHSPKMPP YPPTCAPNLD STRNSEKSGC SAPFPRPKFG RPLKPPSYSS
310 320 330 340 350
HQQSRGGADS SDSQDSQQMD AYVPRHELCL SDPGLEPPVY VPPPSYRSPP
360 370 380 390 400
QNIPNPYLED TVPINVCGGH SQQQSPTEKA GASGQPPSGP PGTGNEYGVS
410 420 430 440 450
PRLPQGLPAH PRPVTAYDGF VQYIPFDDPR LRHFKLAQPQ GFCEDIKLDD
460 470 480 490 500
KSYNSSPVTA QEPAHGGMQP DGAIWNPQSL IPPSGDERGL VLADSSPRWL
510 520 530 540 550
WGQPPGDGEN SGLPNQRDRC VARGQWPDVR GSQHGHTGRQ VSSPYSQGES
560 570 580 590 600
TCETQTKLKK FQTGTRTKKS SKKKMNETIF CLVSIPVKSE SHLPDRDMDN
610 620 630 640 650
NDLKPSADQK NGSDKSPALQ EQSLLSMSST DLELQALTGS MGGRTEFQKQ
660 670 680 690 700
DLGEPEEDRQ TNDLSFIHLT KHRELKHSGS WPGHRYRDQQ TQTSFSEEPQ
710 720 730 740 750
SSQLLPGAKL GGPSRAALSP KCSDPAASEA QTHTAFPTGD HKQRPSARNL
760 770 780 790 800
KGHRSLSPSS NSAFSRTSLS VDQAPTPKAG RSQPCVDVHG LGAHPGPKRE
810 820 830 840 850
VVKGEPTGPC NSKQLFGQFL LKPVSRRPWD LISQLESFNK ELQEEEESSS
860 870 880 890 900
SSSSSSSSSE ESEAEPQQEN RAHCRQEDVG FRGNSPEMRV EPQPRMWVPE
910 920 930 940 950
SPVCRSGRGE SKSESWSEEL QPGHPRAWPP SPGRFRVEEG GGAPFCSADG
960 970 980 990 1000
STSAEKRHLE VSNGMDELAG SPFPVTRMSS RSSDAKPLPA SYPAEPREPQ
1010 1020 1030 1040 1050
ESPKITSAFS SVKPSEAVPR KFDSGGERGA GLPLSLSNKN RGLSAPDLRS
1060 1070 1080 1090 1100
VGLTPGQEQG ASELEGSLGE ASTIEIPPGE SLQARAARIL GIEVAVESLL
1110 1120 1130 1140 1150
PGIRRAGQNQ PAEPDASACT PESPQEELLS RPAPADVPRV STDAFYGRRK
1160 1170 1180 1190 1200
CGWTKSPLFV GDRDSARRAP QAFEHSDVDG VVTSTDPVPE PEPSPLESKF
1210 1220 1230 1240 1250
FEQKDVETKP PFRSTLFHFV ERTPSVAGSE KRLRSPSKVI ESLQEKLASP
1260 1270 1280 1290 1300
PRRADPDRLM RMKEVSSVSR MRVLSFRNAD SQEDAEELKA TTRGQAGLPG
1310 1320 1330 1340 1350
GLVSPGSGDR AQRLGHSLSV SKDSISREEK EHPAAQKEKS MDQDFWCPDS

YDPSRVERV
Length:1,359
Mass (Da):148,351
Last modified:January 15, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0104E6B4A7946D1F
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA95986 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAI46027 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti813K → R in CAI46027 (PubMed:17974005).Curated1
Sequence conflicti852S → G in AAH47548 (PubMed:15489334).Curated1
Sequence conflicti1083Q → R in AAH47548 (PubMed:15489334).Curated1
Sequence conflicti1348P → R in AAH47548 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_037867487E → D. Corresponds to variant dbSNP:rs7917573Ensembl.1
Natural variantiVAR_037868494D → N. Corresponds to variant dbSNP:rs7917566Ensembl.1
Natural variantiVAR_037869729E → A. Corresponds to variant dbSNP:rs7901855Ensembl.1
Natural variantiVAR_037870957R → G3 PublicationsCorresponds to variant dbSNP:rs2185724Ensembl.1
Natural variantiVAR_0378711002S → T1 PublicationCorresponds to variant dbSNP:rs3739998Ensembl.1
Natural variantiVAR_0378721095A → G. Corresponds to variant dbSNP:rs12240677Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB040895 mRNA Translation: BAA95986.2 Different initiation.
AL158036 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86016.1
AL583916 mRNA Translation: CAC29500.1
BX648773 mRNA Translation: CAI46027.1 Different initiation.
BC047548 mRNA Translation: AAH47548.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS41500.1

NCBI Reference Sequences

More...
RefSeqi
NP_065899.1, NM_020848.2
XP_011517910.1, XM_011519608.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000375377; ENSP00000364526; ENSG00000165757

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57608

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57608

UCSC genome browser

More...
UCSCi
uc001iux.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB040895 mRNA Translation: BAA95986.2 Different initiation.
AL158036 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86016.1
AL583916 mRNA Translation: CAC29500.1
BX648773 mRNA Translation: CAI46027.1 Different initiation.
BC047548 mRNA Translation: AAH47548.1
CCDSiCCDS41500.1
RefSeqiNP_065899.1, NM_020848.2
XP_011517910.1, XM_011519608.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi121655, 8 interactors
IntActiQ9P266, 4 interactors
MINTiQ9P266
STRINGi9606.ENSP00000364526

PTM databases

iPTMnetiQ9P266
PhosphoSitePlusiQ9P266

Genetic variation databases

BioMutaiJCAD
DMDMi166218835

Proteomic databases

EPDiQ9P266
jPOSTiQ9P266
MassIVEiQ9P266
MaxQBiQ9P266
PaxDbiQ9P266
PeptideAtlasiQ9P266
PRIDEiQ9P266
ProteomicsDBi83737

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2803, 26 antibodies

Genome annotation databases

EnsembliENST00000375377; ENSP00000364526; ENSG00000165757
GeneIDi57608
KEGGihsa:57608
UCSCiuc001iux.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57608
DisGeNETi57608

GeneCards: human genes, protein and diseases

More...
GeneCardsi
JCAD
HGNCiHGNC:29283, JCAD
HPAiENSG00000165757, Low tissue specificity
MIMi614398, gene
neXtProtiNX_Q9P266
OpenTargetsiENSG00000165757
PharmGKBiPA134955526
VEuPathDBiHostDB:ENSG00000165757.8

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QURJ, Eukaryota
GeneTreeiENSGT00390000015348
HOGENOMiCLU_005347_0_0_1
InParanoidiQ9P266
OMAiGGAPFCS
OrthoDBi208373at2759
PhylomeDBiQ9P266
TreeFamiTF335913

Enzyme and pathway databases

PathwayCommonsiQ9P266

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
57608, 6 hits in 986 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
KIAA1462, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57608
PharosiQ9P266, Tbio

Protein Ontology

More...
PROi
PR:Q9P266
RNActiQ9P266, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000165757, Expressed in amniotic fluid and 230 other tissues
GenevisibleiQ9P266, HS

Family and domain databases

InterProiView protein in InterPro
IPR028221, JCAD
PANTHERiPTHR34757, PTHR34757, 1 hit
PfamiView protein in Pfam
PF15351, JCAD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJCAD_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9P266
Secondary accession number(s): Q5HYA7
, Q5T992, Q86WZ9, Q9BYJ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: April 7, 2021
This is version 124 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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