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Entry version 156 (22 Apr 2020)
Sequence version 3 (18 May 2010)
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Protein

Contactin-3

Gene

CNTN3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Contactin-3
Alternative name(s):
Brain-derived immunoglobulin superfamily protein 1
Short name:
BIG-1
Plasmacytoma-associated neuronal glycoprotein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CNTN3
Synonyms:KIAA1496, PANG
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:2173 CNTN3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
601325 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9P232

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
5067

Open Targets

More...
OpenTargetsi
ENSG00000113805

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA26687

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9P232 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CNTN3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296439395

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001470520 – 1002Contactin-3Add BLAST983
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_00000147061003 – 1028Removed in mature formSequence analysisAdd BLAST26

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi50 ↔ 100PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi65N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi144 ↔ 196PROSITE-ProRule annotation
Glycosylationi193N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi249 ↔ 297PROSITE-ProRule annotation
Disulfide bondi339 ↔ 386PROSITE-ProRule annotation
Glycosylationi375N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi431 ↔ 479PROSITE-ProRule annotation
Glycosylationi468N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi489N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi521 ↔ 577PROSITE-ProRule annotation
Glycosylationi765N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi860N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi895N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi913N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi931N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi956N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi1002GPI-anchor amidated serineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9P232

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9P232

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9P232

PeptideAtlas

More...
PeptideAtlasi
Q9P232

PRoteomics IDEntifications database

More...
PRIDEi
Q9P232

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83720

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1931

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9P232

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9P232

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In brain, it is expressed in frontal lobe, occipital lobe, cerebellum and amygdala.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000113805 Expressed in pigmented layer of retina and 158 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9P232 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000113805 Tissue enhanced (brain, fallopian tube)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PTPRG.

1 Publication

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9P232, 4 interactors

Molecular INTeraction database

More...
MINTi
Q9P232

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000263665

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9P232 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11028
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9P232

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9P232

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini26 – 117Ig-like C2-type 1Add BLAST92
Domaini122 – 208Ig-like C2-type 2Add BLAST87
Domaini227 – 313Ig-like C2-type 3Add BLAST87
Domaini318 – 402Ig-like C2-type 4Add BLAST85
Domaini408 – 497Ig-like C2-type 5Add BLAST90
Domaini499 – 593Ig-like C2-type 6Add BLAST95
Domaini600 – 698Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST99
Domaini703 – 800Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST98
Domaini805 – 901Fibronectin type-III 3PROSITE-ProRule annotationAdd BLAST97
Domaini902 – 998Fibronectin type-III 4PROSITE-ProRule annotationAdd BLAST97

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3513 Eukaryota
ENOG410XSVG LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160282

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005756_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9P232

KEGG Orthology (KO)

More...
KOi
K06761

Identification of Orthologs from Complete Genome Data

More...
OMAi
YSQDKHS

Database of Orthologous Groups

More...
OrthoDBi
655902at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9P232

TreeFam database of animal gene trees

More...
TreeFami
TF351103

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 4 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 10 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041 fn3, 4 hits
PF07679 I-set, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060 FN3, 4 hits
SM00409 IG, 6 hits
SM00408 IGc2, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 6 hits
SSF49265 SSF49265, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853 FN3, 4 hits
PS50835 IG_LIKE, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9P232-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMFPWKQLIL LSFIGCLGGE LLLQGPVFIK EPSNSIFPVG SEDKKITLHC
60 70 80 90 100
EARGNPSPHY RWQLNGSDID MSMEHRYKLN GGNLVVINPN RNWDTGTYQC
110 120 130 140 150
FATNSLGTIV SREAKLQFAY LENFKTKMRS TVSVREGQGV VLLCGPPPHS
160 170 180 190 200
GELSYAWIFN EYPSFVEEDS RRFVSQETGH LYISKVEPSD VGNYTCVVTS
210 220 230 240 250
MVTNARVLGS PTPLVLRSDG VMGEYEPKIE VQFPETLPAA KGSTVKLECF
260 270 280 290 300
ALGNPIPQIN WRRSDGLPFS SKIKLRKFSG VLEIPNFQQE DAGSYECIAE
310 320 330 340 350
NSRGKNVARG RLTYYAKPHW VQLIKDVEIA VEDSLYWECR ASGKPKPSYR
360 370 380 390 400
WLKNGAALVL EERTQIENGA LTISNLSVTD SGMFQCIAEN KHGLVYSSAE
410 420 430 440 450
LKVVASAPDF SKNPMKKLVQ VQVGSLVSLD CKPRASPRAL SSWKKGDVSV
460 470 480 490 500
QEHERISLLN DGGLKIANVT KADAGTYTCM AENQFGKANG TTHLVVTEPT
510 520 530 540 550
RITLAPSNMD VSVGESVILP CQVQHDPLLD IIFTWYFNGA LADFKKDGSH
560 570 580 590 600
FEKVGGSSSG DLMIRNIQLK HSGKYVCMVQ TGVDSVSSAA DLIVRGSPGP
610 620 630 640 650
PENVKVDEIT DTTAQLSWKE GKDNHSPVIS YSIQARTPFS VGWQTVTTVP
660 670 680 690 700
EVIDGKTHTA TVVELNPWVE YEFRVVASNK IGGGEPSLPS EKVRTEEAVP
710 720 730 740 750
EVPPSEVNGG GGSRSELVIT WDPVPEELQN GEGFGYVVAF RPLGVTTWIQ
760 770 780 790 800
TVVTSPDTPR YVFRNESIVP YSPYEVKVGV YNNKGEGPFS PVTTVFSAEE
810 820 830 840 850
EPTVAPSQVS ANSLSSSEIE VSWNTIPWKL SNGHLLGYEV RYWNGGGKEE
860 870 880 890 900
SSSKMKVAGN ETSARLRGLK SNLAYYTAVR AYNSAGAGPF SATVNVTTKK
910 920 930 940 950
TPPSQPPGNV VWNATDTKVL LNWEQVKAME NESEVTGYKV FYRTSSQNNV
960 970 980 990 1000
QVLNTNKTSA ELVLPIKEDY IIEVKATTDG GDGTSSEQIR IPRITSMDAR
1010 1020
GSTSAISNVH PMSSYMPIVL FLIVYVLW
Length:1,028
Mass (Da):112,883
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i575945CD75D21844
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_019906630S → N. Corresponds to variant dbSNP:rs626578Ensembl.1
Natural variantiVAR_056042708N → S1 PublicationCorresponds to variant dbSNP:rs626578Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC016950 Genomic DNA No translation available.
AC024222 Genomic DNA No translation available.
AC128653 Genomic DNA No translation available.
AC128656 Genomic DNA No translation available.
BC150608 mRNA Translation: AAI50609.1
AB040929 mRNA Translation: BAA96020.1
AL512746 mRNA Translation: CAC21671.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33790.1

NCBI Reference Sequences

More...
RefSeqi
NP_065923.1, NM_020872.2
XP_005264814.1, XM_005264757.3
XP_016861996.1, XM_017006507.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000263665; ENSP00000263665; ENSG00000113805

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5067

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:5067

UCSC genome browser

More...
UCSCi
uc003dpm.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016950 Genomic DNA No translation available.
AC024222 Genomic DNA No translation available.
AC128653 Genomic DNA No translation available.
AC128656 Genomic DNA No translation available.
BC150608 mRNA Translation: AAI50609.1
AB040929 mRNA Translation: BAA96020.1
AL512746 mRNA Translation: CAC21671.1
CCDSiCCDS33790.1
RefSeqiNP_065923.1, NM_020872.2
XP_005264814.1, XM_005264757.3
XP_016861996.1, XM_017006507.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WJ3NMR-A893-996[»]
SMRiQ9P232
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiQ9P232, 4 interactors
MINTiQ9P232
STRINGi9606.ENSP00000263665

PTM databases

GlyConnecti1931
iPTMnetiQ9P232
PhosphoSitePlusiQ9P232

Polymorphism and mutation databases

BioMutaiCNTN3
DMDMi296439395

Proteomic databases

jPOSTiQ9P232
MassIVEiQ9P232
PaxDbiQ9P232
PeptideAtlasiQ9P232
PRIDEiQ9P232
ProteomicsDBi83720

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1216 160 antibodies

Genome annotation databases

EnsembliENST00000263665; ENSP00000263665; ENSG00000113805
GeneIDi5067
KEGGihsa:5067
UCSCiuc003dpm.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5067
DisGeNETi5067

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CNTN3
HGNCiHGNC:2173 CNTN3
HPAiENSG00000113805 Tissue enhanced (brain, fallopian tube)
MIMi601325 gene
neXtProtiNX_Q9P232
OpenTargetsiENSG00000113805
PharmGKBiPA26687

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3513 Eukaryota
ENOG410XSVG LUCA
GeneTreeiENSGT00940000160282
HOGENOMiCLU_005756_0_0_1
InParanoidiQ9P232
KOiK06761
OMAiYSQDKHS
OrthoDBi655902at2759
PhylomeDBiQ9P232
TreeFamiTF351103

Enzyme and pathway databases

ReactomeiR-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
CNTN3 human
EvolutionaryTraceiQ9P232

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
CNTN3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
5067
PharosiQ9P232 Tbio

Protein Ontology

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PROi
PR:Q9P232
RNActiQ9P232 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000113805 Expressed in pigmented layer of retina and 158 other tissues
GenevisibleiQ9P232 HS

Family and domain databases

CDDicd00063 FN3, 4 hits
Gene3Di2.60.40.10, 10 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF00041 fn3, 4 hits
PF07679 I-set, 2 hits
SMARTiView protein in SMART
SM00060 FN3, 4 hits
SM00409 IG, 6 hits
SM00408 IGc2, 6 hits
SUPFAMiSSF48726 SSF48726, 6 hits
SSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 4 hits
PS50835 IG_LIKE, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCNTN3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9P232
Secondary accession number(s): B9EK50, Q9H039
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: May 18, 2010
Last modified: April 22, 2020
This is version 156 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  6. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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