Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Coiled-coil domain-containing protein 180

Gene

CCDC180

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 180
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC180
Synonyms:C9orf174, KIAA1529
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000197816.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29303 CCDC180

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9P1Z9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
100499483

Open Targets

More...
OpenTargetsi
ENSG00000197816

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA165585576

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC180

Domain mapping of disease mutations (DMDM)

More...
DMDMi
166218818

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003152331 – 1701Coiled-coil domain-containing protein 180Add BLAST1701

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9P1Z9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9P1Z9

PeptideAtlas

More...
PeptideAtlasi
Q9P1Z9

PRoteomics IDEntifications database

More...
PRIDEi
Q9P1Z9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
83688
83689 [Q9P1Z9-2]
83690 [Q9P1Z9-3]
83691

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9P1Z9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9P1Z9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000197816 Expressed in 92 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_KIAA1529

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9P1Z9 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9P1Z9, 22 interactors

Molecular INTeraction database

More...
MINTi
Q9P1Z9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000364348

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9P1Z9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9P1Z9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili171 – 198Sequence analysisAdd BLAST28
Coiled coili757 – 804Sequence analysisAdd BLAST48

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IG2N Eukaryota
ENOG41100NC LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153246

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG097391

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9P1Z9

Identification of Orthologs from Complete Genome Data

More...
OMAi
TRPDCMY

Database of Orthologous Groups

More...
OrthoDBi
EOG091G00O0

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9P1Z9

TreeFam database of animal gene trees

More...
TreeFami
TF329281

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026701 CCDC180
IPR028089 DUF4455
IPR027914 DUF4456

The PANTHER Classification System

More...
PANTHERi
PTHR21444:SF14 PTHR21444:SF14, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14643 DUF4455, 1 hit
PF14644 DUF4456, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 2 (identifier: Q9P1Z9-2) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRGGENRPPA RVQSSSEELE LRHQSLDAFP GRRLPGRGIQ PAAKMSSVGK
60 70 80 90 100
VTQVPNGKAY QQIFQAEVQL VHSLAATRKR AAERSVTLKS GRIPMMKKVE
110 120 130 140 150
TPEGEVMSPR QQKWMHSLPN DWIMENPVLH REKERAKREK ARESENTIAA
160 170 180 190 200
REVRGLMDTI VPEKISTSTF QRQAEHKRKS YESALASFQE EIAQVGKEME
210 220 230 240 250
PLIVDTGGLF LKKLTESDEE MNRLFLKVEN DTNLEDYTIQ ALLELWDKVA
260 270 280 290 300
GRLLLRKQEI KELDEALHSL EFSRTDKLKS VLKKYAEVIE KTSYLMRPEV
310 320 330 340 350
YRLINEEAMV MNYALLGNRK ALAQLFVNLM ESTLQQELDS RHRWQGLVDT
360 370 380 390 400
WKALKKEALL QSFSEFMASE SIHTPPAVTK ELEVMLKTQN VLQQRRLKHL
410 420 430 440 450
CTICDLLPPS YSKTQLTEWH SSLNSLNKEL DTYHVDCMMR IRLLYEKTWQ
460 470 480 490 500
ECLMHVQNCK KQLLDWKAFT EEEAETLVNQ FFFQMVGALQ GKVEEDLELL
510 520 530 540 550
DKSFETLADQ TEWQSSHLFK YFQEVVQLWE AHQSELLVQE LELEKRMEQH
560 570 580 590 600
RQKHSLESQV QEAHLDRLLD QLRQQSDKET LAFHLEKVKD YLKNMKSRYE
610 620 630 640 650
CFHTLLTKEV MEYPAIMLKE LNSYSSALSQ YFFVREIFEQ NLAGEVIFKF
660 670 680 690 700
RQPEAHEKPS QKRVKKLRKK QGSKEDMTRS EESISSGTST ARSVEEVEEE
710 720 730 740 750
NDQEMESFIT EEVLGQQKKS PLHAKMDESK EGSIQGLEEM QVEREGSLNP
760 770 780 790 800
SLNEENVKGQ GEKKEESEEE DEKEEEEEEE KLEEEKEEKE AQEEQESLSV
810 820 830 840 850
GEEEDKEEGL EEIYYEDMES FTISSGNTYF VFVPLEEEHC RKSHSTFSAM
860 870 880 890 900
FINDTSSAKF IEQVTIPSRL ILEIKKQLRA GFFEHLEKWF DQCSLNTRVT
910 920 930 940 950
VATKINELDS ELELHLHLHQ PRAQQIEKDI HNVRAAELLL HQEQLDSHCA
960 970 980 990 1000
GVTETLKKKR LMFCQFQEEQ NVRSKNFRLK IYDMEHIFLN ATRSQKLVTL
1010 1020 1030 1040 1050
SNTLHQELLS YVDVTQVSLR SFRQYLEESL GKLRYSNIEF IKHCRLFSEG
1060 1070 1080 1090 1100
GNFSPKEINS LCSRLEKEAA RIELVESVIM LNMEKLENEY LDQANDVINK
1110 1120 1130 1140 1150
FESKFHNLSV DLIFIEKIQR LLTNLQVKIK CQVAKSNSQT NGLNFSLQQL
1160 1170 1180 1190 1200
QNKIKTCQES RGEKTTVTTE ELLSFVQTWK EKLSQRIQYL NCSLDRVSMT
1210 1220 1230 1240 1250
ELVFTNTILK DQEEDSDILT SSEALEEEAK LDVVTPESFT QLSRVGKPLI
1260 1270 1280 1290 1300
EDPAVDVIRK LLQLPNTKWP THHCDKDPSQ TGRGAWACGS RGSSEAGAGG
1310 1320 1330 1340 1350
AVCSPPVLCS CPGPSSPKGF KRHRCQPENS GKKAVPSASA TSAGSFTPHP
1360 1370 1380 1390 1400
KPNKMERKYR VLGDKPPPAA EDFKGIILTL LWESSENLLT VAEEFYRKEK
1410 1420 1430 1440 1450
RPVTRPDCMC DTFDQCAENI SKKILEYQSQ ANKYHNSCLI ELRIQIRRFE
1460 1470 1480 1490 1500
ELLPQVCWLV MENFKEHHWK KFFTSVKEIR GQFEEQQKRL EKRKDKNAQK
1510 1520 1530 1540 1550
LHLNLGHPVH FQEMESLHLS EEERQEELDS MIRMNKEKLE ECTRRNGQVF
1560 1570 1580 1590 1600
ITNLATFTEK FLLQLDEVVT IDDVQVARME PPKQKLSMLI RRKLAGLSLK
1610 1620 1630 1640 1650
EESEKPLIER GSRKWPGIKP TEVTIQNKIL LQPTSSISTT KTTLGHLAAV
1660 1670 1680 1690 1700
EARDAVYLKY LASFEEELKR IQDDCTSQIK EAQRWKDSWK QSLHTIQGLY

V
Note: No experimental confirmation available.
Length:1,701
Mass (Da):197,344
Last modified:September 12, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i05C4909D40A2577B
GO
Isoform 3 (identifier: Q9P1Z9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1578: Missing.

Note: No experimental confirmation available.
Show »
Length:123
Mass (Da):14,106
Checksum:i12ED34125326E7B9
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI12931 differs from that shown. Readthrough transcript which is the product of an upstream read-through pseudogene (SUGT1P4-STRA6LP) with CCDC180.Curated
The sequence BAA96053 differs from that shown. Readthrough transcript which is the product of an upstream read-through pseudogene (SUGT1P4-STRA6LP) with CCDC180.Curated
The sequence CAH10534 differs from that shown. Intron retention.Curated
The sequence CAH10534 differs from that shown. Reason: Frameshift at several positions.Curated
The sequence CAH18175 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti209L → F in CAH18175 (PubMed:17974005).Curated1
Sequence conflicti283K → M in CAH18175 (PubMed:17974005).Curated1
Sequence conflicti1112L → P in CAH18175 (PubMed:17974005).Curated1
Sequence conflicti1206N → I in CAH18175 (PubMed:17974005).Curated1
Sequence conflicti1651E → D in CAH18175 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_038151162P → H. Corresponds to variant dbSNP:rs7864805Ensembl.1
Natural variantiVAR_038152183S → R. Corresponds to variant dbSNP:rs17855671Ensembl.1
Natural variantiVAR_038153234L → H. Corresponds to variant dbSNP:rs10981558Ensembl.1
Natural variantiVAR_061250409P → R. Corresponds to variant dbSNP:rs61261278Ensembl.1
Natural variantiVAR_038154778E → K. Corresponds to variant dbSNP:rs12353306Ensembl.1
Natural variantiVAR_038155856S → C. Corresponds to variant dbSNP:rs2061634Ensembl.1
Natural variantiVAR_0381561175F → L. Corresponds to variant dbSNP:rs3747495Ensembl.1
Natural variantiVAR_0381571573D → N. Corresponds to variant dbSNP:rs2306093Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0596871 – 1578Missing in isoform 3. Add BLAST1578

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB040962 mRNA Translation: BAA96053.1 Sequence problems.
AL137557 mRNA Translation: CAH10701.1
CR627453 mRNA Translation: CAH10534.1 Sequence problems.
CR749320 mRNA Translation: CAH18175.1 Different initiation.
AL512590 Genomic DNA No translation available.
CH471105 Genomic DNA Translation: EAW58840.1
BC112930 mRNA Translation: AAI12931.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS35077.2 [Q9P1Z9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_065944.2, NM_020893.3 [Q9P1Z9-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.435629

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000529487; ENSP00000434727; ENSG00000197816 [Q9P1Z9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100499483

UCSC genome browser

More...
UCSCi
uc004axg.3 human [Q9P1Z9-2]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB040962 mRNA Translation: BAA96053.1 Sequence problems.
AL137557 mRNA Translation: CAH10701.1
CR627453 mRNA Translation: CAH10534.1 Sequence problems.
CR749320 mRNA Translation: CAH18175.1 Different initiation.
AL512590 Genomic DNA No translation available.
CH471105 Genomic DNA Translation: EAW58840.1
BC112930 mRNA Translation: AAI12931.1 Sequence problems.
CCDSiCCDS35077.2 [Q9P1Z9-2]
RefSeqiNP_065944.2, NM_020893.3 [Q9P1Z9-2]
UniGeneiHs.435629

3D structure databases

ProteinModelPortaliQ9P1Z9
SMRiQ9P1Z9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9P1Z9, 22 interactors
MINTiQ9P1Z9
STRINGi9606.ENSP00000364348

PTM databases

iPTMnetiQ9P1Z9
PhosphoSitePlusiQ9P1Z9

Polymorphism and mutation databases

BioMutaiCCDC180
DMDMi166218818

Proteomic databases

MaxQBiQ9P1Z9
PaxDbiQ9P1Z9
PeptideAtlasiQ9P1Z9
PRIDEiQ9P1Z9
ProteomicsDBi83688
83689 [Q9P1Z9-2]
83690 [Q9P1Z9-3]
83691

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000529487; ENSP00000434727; ENSG00000197816 [Q9P1Z9-2]
GeneIDi100499483
UCSCiuc004axg.3 human [Q9P1Z9-2]

Organism-specific databases

DisGeNETi100499483
EuPathDBiHostDB:ENSG00000197816.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC180

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0008209
HGNCiHGNC:29303 CCDC180
neXtProtiNX_Q9P1Z9
OpenTargetsiENSG00000197816
PharmGKBiPA165585576

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IG2N Eukaryota
ENOG41100NC LUCA
GeneTreeiENSGT00940000153246
HOVERGENiHBG097391
InParanoidiQ9P1Z9
OMAiTRPDCMY
OrthoDBiEOG091G00O0
PhylomeDBiQ9P1Z9
TreeFamiTF329281

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CCDC180 human

Protein Ontology

More...
PROi
PR:Q9P1Z9

Gene expression databases

BgeeiENSG00000197816 Expressed in 92 organ(s), highest expression level in testis
CleanExiHS_KIAA1529
GenevisibleiQ9P1Z9 HS

Family and domain databases

InterProiView protein in InterPro
IPR026701 CCDC180
IPR028089 DUF4455
IPR027914 DUF4456
PANTHERiPTHR21444:SF14 PTHR21444:SF14, 1 hit
PfamiView protein in Pfam
PF14643 DUF4455, 1 hit
PF14644 DUF4456, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCC180_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9P1Z9
Secondary accession number(s): Q2KHR6
, Q5VV25, Q68DP5, Q69YV9, Q6AHY0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 12, 2018
Last modified: December 5, 2018
This is version 110 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again