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Entry version 155 (22 Apr 2020)
Sequence version 1 (01 Oct 2000)
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Protein

Zinc finger protein 581

Gene

ZNF581

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri87 – 109C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri115 – 137C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri145 – 167C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri173 – 196C2H2-type 4PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 581
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF581
ORF Names:HSPC189
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25017 ZNF581

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9P0T4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000171425

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134899657

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9P0T4 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF581

Domain mapping of disease mutations (DMDM)

More...
DMDMi
55976774

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476731 – 197Zinc finger protein 581Add BLAST197

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9P0T4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9P0T4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9P0T4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9P0T4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9P0T4

PeptideAtlas

More...
PeptideAtlasi
Q9P0T4

PRoteomics IDEntifications database

More...
PRIDEi
Q9P0T4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83595

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9P0T4

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
Q9P0T4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9P0T4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000171425 Expressed in islet of Langerhans and 179 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9P0T4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9P0T4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000171425 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q9P0T4
With#Exp.IntAct
AP2M1 [Q96CW1]3EBI-745520,EBI-297683
APOBEC3C [Q9NRW3]3EBI-745520,EBI-1044593
ASB13 - isoform 2 [Q8WXK3-2]3EBI-745520,EBI-12015080
ATG9A - isoform 3 [Q7Z3C6-3]3EBI-745520,EBI-12006308
BANP [Q8N9N5]3EBI-745520,EBI-744695
BANP - isoform 2 [Q8N9N5-2]3EBI-745520,EBI-11524452
BOLA2B [A0A087WZT3]3EBI-745520,EBI-12006120
BYSL [Q13895]3EBI-745520,EBI-358049
CALCOCO2 [Q13137]3EBI-745520,EBI-739580
CARD10 [Q9BWT7]3EBI-745520,EBI-3866279
CCDC136 - isoform 2 [Q96JN2-2]3EBI-745520,EBI-10171416
CCNDBP1 [O95273]3EBI-745520,EBI-748961
CHURC1 [Q8WUH1]3EBI-745520,EBI-11156883
CNFN [Q9BYD5]3EBI-745520,EBI-12819063
CYSRT1 [A8MQ03]6EBI-745520,EBI-3867333
DOCK8 - isoform 2 [Q8NF50-2]3EBI-745520,EBI-10174653
DVL3 [Q92997]3EBI-745520,EBI-739789
EFEMP2 [O95967]3EBI-745520,EBI-743414
ENKD1 [Q9H0I2]3EBI-745520,EBI-744099
ETFDH [Q16134]3EBI-745520,EBI-2870454
FAM90A1 [Q86YD7]3EBI-745520,EBI-6658203
FANCL [Q9NW38]3EBI-745520,EBI-2339898
FHL5 [Q5TD97]3EBI-745520,EBI-750641
FSD2 [A1L4K1]6EBI-745520,EBI-5661036
GOLGA2 [Q08379]3EBI-745520,EBI-618309
GOLGA6L9 [A6NEM1]3EBI-745520,EBI-5916454
GOPC [Q9HD26]3EBI-745520,EBI-349832
GPSM3 [Q9Y4H4]3EBI-745520,EBI-347538
HMBOX1 [Q6NT76]6EBI-745520,EBI-2549423
HNRNPF [P52597]3EBI-745520,EBI-352986
HSF2BP [O75031]6EBI-745520,EBI-7116203
IKZF1 [Q13422]3EBI-745520,EBI-745305
IL16 - isoform 2 [Q14005-2]3EBI-745520,EBI-17178971
KHDRBS2 [Q5VWX1]3EBI-745520,EBI-742808
KRT27 [Q7Z3Y8]3EBI-745520,EBI-3044087
KRT34 [O76011]3EBI-745520,EBI-1047093
KRT40 [Q6A162]6EBI-745520,EBI-10171697
KRTAP1-1 [Q07627]3EBI-745520,EBI-11959885
KRTAP10-7 [P60409]6EBI-745520,EBI-10172290
KRTAP10-8 [P60410]3EBI-745520,EBI-10171774
KRTAP10-9 [P60411]3EBI-745520,EBI-10172052
KRTAP12-2 [P59991]3EBI-745520,EBI-10176379
KRTAP2-4 [Q9BYR9]3EBI-745520,EBI-14065470
KRTAP4-12 [Q9BQ66]4EBI-745520,EBI-739863
KRTAP4-2 [Q9BYR5]3EBI-745520,EBI-10172511
KRTAP5-9 [P26371]3EBI-745520,EBI-3958099
KRTAP6-2 [Q3LI66]3EBI-745520,EBI-11962084
LNX1 [Q8TBB1]6EBI-745520,EBI-739832
LZTS2 [Q9BRK4]4EBI-745520,EBI-741037
MDFI [Q99750]8EBI-745520,EBI-724076
MTUS2 [Q5JR59]4EBI-745520,EBI-742948
NID2 [Q8IV28]3EBI-745520,EBI-10261509
NOTCH2NLA [Q7Z3S9]3EBI-745520,EBI-945833
NOTCH2NLC [P0DPK4]3EBI-745520,EBI-22310682
NUDT22 [Q9BRQ3]3EBI-745520,EBI-10297093
PDE4DIP [Q5VU43]3EBI-745520,EBI-1105124
PDE4DIP - isoform 2 [Q5VU43-2]3EBI-745520,EBI-9640281
PLAGL2 [Q9UPG8]3EBI-745520,EBI-2876622
PLEKHF2 [Q9H8W4]3EBI-745520,EBI-742388
PNMA1 [Q8ND90]8EBI-745520,EBI-302345
POU2AF1 [Q16633]3EBI-745520,EBI-943588
PRKAB2 [O43741]3EBI-745520,EBI-1053424
RBPMS [Q93062]4EBI-745520,EBI-740322
RBPMS - isoform C [Q93062-3]8EBI-745520,EBI-740343
RIMBP3 [Q9UFD9]3EBI-745520,EBI-10182375
RSKR [Q96LW2]3EBI-745520,EBI-1054572
SDCBP2 [Q9H190]3EBI-745520,EBI-742426
SERTAD2 [Q14140]3EBI-745520,EBI-2822051
SMARCC1 [Q92922]3EBI-745520,EBI-355653
SOX5 [P35711]3EBI-745520,EBI-3505701
SPAG8 - isoform 2 [Q99932-2]3EBI-745520,EBI-11959123
SPERT [Q8NA61]3EBI-745520,EBI-741724
SPERT - isoform 2 [Q8NA61-2]3EBI-745520,EBI-11524851
SPG21 [Q9NZD8]3EBI-745520,EBI-742688
TEKT4 [Q8WW24]3EBI-745520,EBI-750487
TMCC2 - isoform 4 [O75069-4]3EBI-745520,EBI-10177480
TRAF1 [Q13077]3EBI-745520,EBI-359224
TRAF4 [Q9BUZ4]6EBI-745520,EBI-3650647
TRIM23 [P36406]8EBI-745520,EBI-740098
TRIM27 [P14373]6EBI-745520,EBI-719493
TRIP6 [Q15654]3EBI-745520,EBI-742327
WWOX - isoform 5 [Q9NZC7-5]3EBI-745520,EBI-12040603
ZNF765 - isoform 2 [Q7L2R6-2]3EBI-745520,EBI-12834294
ZNF792 [Q3KQV3]3EBI-745520,EBI-10240849
ZRANB1 [Q9UGI0]3EBI-745520,EBI-527853

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119601, 52 interactors

Protein interaction database and analysis system

More...
IntActi
Q9P0T4, 102 interactors

Molecular INTeraction database

More...
MINTi
Q9P0T4

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9P0T4 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri87 – 109C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri115 – 137C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri145 – 167C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri173 – 196C2H2-type 4PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163608

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_42_5_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9P0T4

Identification of Orthologs from Complete Genome Data

More...
OMAi
KHARWKH

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9P0T4

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096 zf-C2H2, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9P0T4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLVLPSPCPQ PLAFSSVETM EGPPRRTCRS PEPGPSSSIG SPQASSPPRP
60 70 80 90 100
NHYLLIDTQG VPYTVLVDEE SQREPGASGA PGQKKCYSCP VCSRVFEYMS
110 120 130 140 150
YLQRHSITHS EVKPFECDIC GKAFKRASHL ARHHSIHLAG GGRPHGCPLC
160 170 180 190
PRRFRDAGEL AQHSRVHSGE RPFQCPHCPR RFMEQNTLQK HTRWKHP
Length:197
Mass (Da):22,010
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB62F1FAFD4829EE5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EM32K7EM32_HUMAN
Zinc finger protein 581
ZNF581
139Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF151023 mRNA Translation: AAF36109.2
AK315603 mRNA Translation: BAG37973.1
CH471135 Genomic DNA Translation: EAW72400.1
BC010097 mRNA Translation: AAH10097.1
BC001219 mRNA Translation: AAH01219.1
BC071620 mRNA Translation: AAH71620.1
BC071845 mRNA Translation: AAH71845.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12932.1

NCBI Reference Sequences

More...
RefSeqi
NP_057619.1, NM_016535.3
XP_006723303.1, XM_006723240.3
XP_016882356.1, XM_017026867.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000270451; ENSP00000270451; ENSG00000171425
ENST00000587252; ENSP00000466047; ENSG00000171425
ENST00000588537; ENSP00000466564; ENSG00000171425

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51545

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51545

UCSC genome browser

More...
UCSCi
uc002qln.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF151023 mRNA Translation: AAF36109.2
AK315603 mRNA Translation: BAG37973.1
CH471135 Genomic DNA Translation: EAW72400.1
BC010097 mRNA Translation: AAH10097.1
BC001219 mRNA Translation: AAH01219.1
BC071620 mRNA Translation: AAH71620.1
BC071845 mRNA Translation: AAH71845.1
CCDSiCCDS12932.1
RefSeqiNP_057619.1, NM_016535.3
XP_006723303.1, XM_006723240.3
XP_016882356.1, XM_017026867.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi119601, 52 interactors
IntActiQ9P0T4, 102 interactors
MINTiQ9P0T4

PTM databases

iPTMnetiQ9P0T4
MetOSiteiQ9P0T4
PhosphoSitePlusiQ9P0T4

Polymorphism and mutation databases

BioMutaiZNF581
DMDMi55976774

Proteomic databases

EPDiQ9P0T4
jPOSTiQ9P0T4
MassIVEiQ9P0T4
MaxQBiQ9P0T4
PaxDbiQ9P0T4
PeptideAtlasiQ9P0T4
PRIDEiQ9P0T4
ProteomicsDBi83595

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
33134 59 antibodies

Genome annotation databases

EnsembliENST00000270451; ENSP00000270451; ENSG00000171425
ENST00000587252; ENSP00000466047; ENSG00000171425
ENST00000588537; ENSP00000466564; ENSG00000171425
GeneIDi51545
KEGGihsa:51545
UCSCiuc002qln.4 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
51545

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF581
HGNCiHGNC:25017 ZNF581
HPAiENSG00000171425 Low tissue specificity
neXtProtiNX_Q9P0T4
OpenTargetsiENSG00000171425
PharmGKBiPA134899657

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163608
HOGENOMiCLU_002678_42_5_1
InParanoidiQ9P0T4
OMAiKHARWKH
OrthoDBi1318335at2759
PhylomeDBiQ9P0T4

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZNF581 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
51545
PharosiQ9P0T4 Tdark

Protein Ontology

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PROi
PR:Q9P0T4
RNActiQ9P0T4 protein

Gene expression databases

BgeeiENSG00000171425 Expressed in islet of Langerhans and 179 other tissues
ExpressionAtlasiQ9P0T4 baseline and differential
GenevisibleiQ9P0T4 HS

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 4 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN581_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9P0T4
Secondary accession number(s): B2RDM6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: October 1, 2000
Last modified: April 22, 2020
This is version 155 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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