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Entry version 135 (02 Jun 2021)
Sequence version 1 (01 Oct 2000)
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Protein

Mitochondrial transcription rescue factor 1

Gene

MTRES1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation. Functions as a protective factor to maintain proper mitochondrial RNA level during stress. Acts at the transcription level and its protective function depends on its RNA binding ability (PubMed:31226201).

Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation (PubMed:33243891, PubMed:31396629).

As heterodimer with MTRF, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue (PubMed:33243891).

3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9P0P8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mitochondrial transcription rescue factor 11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTRES1Imported
Synonyms:C6orf203
ORF Names:HSPC230
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17971, MTRES1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
618583, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9P0P8

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000130349.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi143R → A: Decreased RNA-binding; when associated with A-145; A-149: A-156 and A-158. Does not rescue diminished mitochondrial transcription induced by EtBr; when associated with A-145; A-149: A-156 and A-158. 1 Publication1
Mutagenesisi145D → A: Decreased RNA-binding; when associated with A-143; A-149: A-156 and A-158. Does not rescue diminished mitochondrial transcription induced by EtBr; when associated with A-143; A-149: A-156 and A-158. 1 Publication1
Mutagenesisi149K → A: Decreased RNA-binding; when associated with A-143; A-145: A-156 and A-158. Does not rescue diminished mitochondrial transcription induced by EtBr; when associated with A-143; A-149: A-156 and A-158. 1 Publication1
Mutagenesisi156R → A: Decreased RNA-binding; when associated with A-143; A-145: A-149 and A-158. Does not rescue diminished mitochondrial transcription induced by EtBr; when associated with A-143; A-145: A-149 and A-158. 1 Publication1
Mutagenesisi158K → A: Decreased RNA-binding; when associated with A-143; A-145: A-149 and A-156. Does not rescue diminished mitochondrial transcription induced by EtBr; when associated with A-143; A-145: A-149 and A-156. 1 Publication1

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000130349

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134898244

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9P0P8, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C6orf203

Domain mapping of disease mutations (DMDM)

More...
DMDMi
71152388

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 84Mitochondrion1 PublicationAdd BLAST84
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000008955985 – 240Mitochondrial transcription rescue factor 1Add BLAST156

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei106PhosphoserineCombined sources1
Modified residuei116PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9P0P8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9P0P8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9P0P8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9P0P8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9P0P8

PeptideAtlas

More...
PeptideAtlasi
Q9P0P8

PRoteomics IDEntifications database

More...
PRIDEi
Q9P0P8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83590

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q9P0P8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9P0P8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9P0P8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated upon depletion of mitochondrial nucleic acids.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000130349, Expressed in oocyte and 214 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9P0P8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9P0P8, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000130349, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer (PubMed:31226201).

Interacts with POLRMT (PubMed:31226201).

Interacts (via S4 domain) with MTRFR (via C-terminus) (PubMed:33243891, PubMed:31396629). Associates with mitoribosomal S39 large subunit, peptidyl tRNA and nascent chain (PubMed:33243891, PubMed:31396629).

3 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
119407, 285 interactors

Protein interaction database and analysis system

More...
IntActi
Q9P0P8, 24 interactors

Molecular INTeraction database

More...
MINTi
Q9P0P8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000384867

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9P0P8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9P0P8

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini142 – 217S4 RNA-bindingPROSITE-ProRule annotation2 PublicationsAdd BLAST76

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni95 – 127DisorderedSequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi107 – 124Acidic residuesSequence analysisAdd BLAST18

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4837, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000009366

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_076117_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9P0P8

Database of Orthologous Groups

More...
OrthoDBi
1440120at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9P0P8

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039167, MTRES1

The PANTHER Classification System

More...
PANTHERi
PTHR13633, PTHR13633, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9P0P8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMASVKLLA GVLRKPDAWI GLWGVLRGTP SSYKLCTSWN RYLYFSSTKL
60 70 80 90 100
RAPNYKTLFY NIFSLRLPGL LLSPECIFPF SVRLKSNIRS TKSTKKSLQK
110 120 130 140 150
VDEEDSDEES HHDEMSEQEE ELEDDPTVVK NYKDLEKAVQ SFRYDVVLKT
160 170 180 190 200
GLDIGRNKVE DAFYKGELRL NEEKLWKKSR TVKVGDTLDL LIGEDKEAGT
210 220 230 240
ETVMRILLKK VFEEKTESEK YRVVLRRWKS LKLPKKRMSK
Length:240
Mass (Da):27,941
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i01E2DBCB11537275
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0D9SEI0A0A0D9SEI0_HUMAN
Mitochondrial transcription rescue ...
MTRES1
245Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF151064 mRNA Translation: AAF36150.1
AK091564 mRNA Translation: BAG52381.1
AL355586 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48402.1
BC010899 mRNA Translation: AAH10899.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5058.1

NCBI Reference Sequences

More...
RefSeqi
NP_001135940.1, NM_001142468.2
NP_001135942.1, NM_001142470.2
NP_057571.1, NM_016487.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000311381; ENSP00000310951; ENSG00000130349
ENST00000405204; ENSP00000384867; ENSG00000130349

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51250

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51250

UCSC genome browser

More...
UCSCi
uc003prq.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF151064 mRNA Translation: AAF36150.1
AK091564 mRNA Translation: BAG52381.1
AL355586 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48402.1
BC010899 mRNA Translation: AAH10899.1
CCDSiCCDS5058.1
RefSeqiNP_001135940.1, NM_001142468.2
NP_001135942.1, NM_001142470.2
NP_057571.1, NM_016487.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
7A5Helectron microscopy3.30G1-240[»]
SMRiQ9P0P8
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi119407, 285 interactors
IntActiQ9P0P8, 24 interactors
MINTiQ9P0P8
STRINGi9606.ENSP00000384867

PTM databases

iPTMnetiQ9P0P8
PhosphoSitePlusiQ9P0P8

Genetic variation databases

BioMutaiC6orf203
DMDMi71152388

Proteomic databases

EPDiQ9P0P8
jPOSTiQ9P0P8
MassIVEiQ9P0P8
MaxQBiQ9P0P8
PaxDbiQ9P0P8
PeptideAtlasiQ9P0P8
PRIDEiQ9P0P8
ProteomicsDBi83590
TopDownProteomicsiQ9P0P8

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
55873, 79 antibodies

The DNASU plasmid repository

More...
DNASUi
51250

Genome annotation databases

EnsembliENST00000311381; ENSP00000310951; ENSG00000130349
ENST00000405204; ENSP00000384867; ENSG00000130349
GeneIDi51250
KEGGihsa:51250
UCSCiuc003prq.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51250

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MTRES1
HGNCiHGNC:17971, MTRES1
HPAiENSG00000130349, Low tissue specificity
MIMi618583, gene
neXtProtiNX_Q9P0P8
OpenTargetsiENSG00000130349
PharmGKBiPA134898244
VEuPathDBiHostDB:ENSG00000130349.9

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4837, Eukaryota
GeneTreeiENSGT00390000009366
HOGENOMiCLU_076117_0_0_1
InParanoidiQ9P0P8
OrthoDBi1440120at2759
PhylomeDBiQ9P0P8

Enzyme and pathway databases

PathwayCommonsiQ9P0P8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
51250, 14 hits in 991 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C6orf203, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
51250
PharosiQ9P0P8, Tdark

Protein Ontology

More...
PROi
PR:Q9P0P8
RNActiQ9P0P8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000130349, Expressed in oocyte and 214 other tissues
ExpressionAtlasiQ9P0P8, baseline and differential
GenevisibleiQ9P0P8, HS

Family and domain databases

InterProiView protein in InterPro
IPR039167, MTRES1
PANTHERiPTHR13633, PTHR13633, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMRES1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9P0P8
Secondary accession number(s): B3KRG9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: October 1, 2000
Last modified: June 2, 2021
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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