RGL1

Protein namesⁱ	Recommended name: Ral guanine nucleotide dissociation stimulator-like 1 Short name: RalGDS-like 1
Gene namesⁱ	Name:RGL1 Synonyms:KIAA0959, RGL
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000143344.15
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:30281 RGL1
MIMⁱ	605667 gene
neXtProtⁱ	NX_Q9NZL6

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	23179
Open Targets More...OpenTargetsⁱ	ENSG00000143344
PharmGKBⁱ	PA134934636

Polymorphism and mutation databases

BioMutaⁱ	RGL1
DMDMⁱ	14548230

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000068885	1 – 768	Ral guanine nucleotide dissociation stimulator-like 1Add BLAST		768

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	520	PhosphoserineBy similarity		1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

EPDⁱ	Q9NZL6
PaxDbⁱ	Q9NZL6
PeptideAtlas More...PeptideAtlasⁱ	Q9NZL6
PRIDEⁱ	Q9NZL6
ProteomicsDBⁱ	83430 83431 [Q9NZL6-2]

PTM databases

iPTMnetⁱ	Q9NZL6
PhosphoSitePlusⁱ	Q9NZL6

Expressionⁱ

Tissue specificityⁱ

Expressed in a wide variety of tissues with strong expression being seen in the heart, brain, kidney, spleen and testis.

Gene expression databases

Bgeeⁱ	ENSG00000143344 Expressed in 235 organ(s), highest expression level in endothelial cell
CleanExⁱ	HS_RGL1
Genevisibleⁱ	Q9NZL6 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA019788

HPAⁱ

HPA019788

Interactionⁱ

Subunit structureⁱ

Interacts with Ras.By similarity

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
HRAS	P01112	3	EBI-365926,EBI-350145

With

Entry

#Exp.

IntAct

Notes

HRAS

P01112

3

EBI-365926,EBI-350145

GO - Molecular functionⁱ

Ral guanyl-nucleotide exchange factor activity
Source: UniProtKB
Non-traceable author statementⁱ
- 10760592

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	116791, 11 interactors
Database of interacting proteins More...DIPⁱ	DIP-31372N
IntActⁱ	Q9NZL6, 2 interactors
STRINGⁱ	9606.ENSP00000303192

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9NZL6
SMRⁱ	Q9NZL6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	65 – 196	N-terminal Ras-GEFPROSITE-ProRule annotationAdd BLAST	132
Domainⁱ	232 – 501	Ras-GEFPROSITE-ProRule annotationAdd BLAST	270
Domainⁱ	648 – 735	Ras-associatingPROSITE-ProRule annotationAdd BLAST	88

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	541 – 613	Ser-richAdd BLAST		73

Phylogenomic databases

eggNOGⁱ	KOG3629 Eukaryota ENOG410ZUT5 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000143985
HOGENOMⁱ	HOG000231592
HOVERGENⁱ	HBG005864
InParanoidⁱ	Q9NZL6
KEGG Orthology (KO) More...KOⁱ	K17635
OMAⁱ	QSAPDFY
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0761
PhylomeDBⁱ	Q9NZL6
TreeFamⁱ	TF315204

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00155 RasGEF, 1 hit cd06224 REM, 1 hit
Gene3Dⁱ	1.10.840.10, 1 hit
InterProⁱ	View protein in InterPro IPR000159 RA_dom IPR008937 Ras-like_GEF IPR000651 Ras-like_Gua-exchang_fac_N IPR019804 Ras_G-nucl-exch_fac_CS IPR023578 Ras_GEF_dom_sf IPR001895 RASGEF_cat_dom IPR036964 RASGEF_cat_dom_sf IPR030748 RGL1 IPR029071 Ubiquitin-like_domsf
PANTHERⁱ	PTHR23113 PTHR23113, 1 hit PTHR23113:SF199 PTHR23113:SF199, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00788 RA, 1 hit PF00617 RasGEF, 1 hit PF00618 RasGEF_N, 1 hit
SMARTⁱ	View protein in SMART SM00314 RA, 1 hit SM00147 RasGEF, 1 hit SM00229 RasGEFN, 1 hit
SUPFAMⁱ	SSF48366 SSF48366, 1 hit SSF54236 SSF54236, 1 hit
PROSITEⁱ	View protein in PROSITE PS50200 RA, 1 hit PS00720 RASGEF, 1 hit PS50009 RASGEF_CAT, 1 hit PS50212 RASGEF_NTER, 1 hit

Sequences (2)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

Isoform A (identifier: Q9NZL6-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKLLWQAKMS SIQDWGEEVE EGAVYHVTLK RVQIQQAANK GARWLGVEGD 
        60         70         80         90        100
QLPPGHTVSQ YETCKIRTIK AGTLEKLVEN LLTAFGDNDF TYISIFLSTY 
       110        120        130        140        150
RGFASTKEVL ELLLDRYGNL TSPNCEEDGS QSSSESKMVI RNAIASILRA 
       160        170        180        190        200
WLDQCAEDFR EPPHFPCLQK LLDYLTRMMP GSDPERRAQN LLEQFQKQEV 
       210        220        230        240        250
ETDNGLPNTI SFSLEEEEEL EGGESAEFTC FSEDLVAEQL TYMDAQLFKK 
       260        270        280        290        300
VVPHHCLGCI WSRRDKKENK HLAPTIRATI SQFNTLTKCV VSTILGGKEL 
       310        320        330        340        350
KTQQRAKIIE KWINIAHECR LLKNFSSLRA IVSALQSNSI YRLKKTWAAV 
       360        370        380        390        400
PRDRMLMFEE LSDIFSDHNN HLTSRELLMK EGTSKFANLD SSVKENQKRT 
       410        420        430        440        450
QRRLQLQKDM GVMQGTVPYL GTFLTDLTML DTALQDYIEG GLINFEKRRR 
       460        470        480        490        500
EFEVIAQIKL LQSACNSYCM TPDQKFIQWF QRQQLLTEEE SYALSCEIEA 
       510        520        530        540        550
AADASTTSPK PRKSMVKRLS LLFLGSDMIT SPTPTKEQPK STASGSSGES 
       560        570        580        590        600
MDSVSVSSCE SNHSEAEEGS ITPMDTPDEP QKKLSESSSS CSSIHSMDTN 
       610        620        630        640        650
SSGMSSLINP LSSPPSCNNN PKIHKRSVSV TSITSTVLPP VYNQQNEDTC 
       660        670        680        690        700
IIRISVEDNN GNMYKSIMLT SQDKTPAVIQ RAMLKHNLDS DPAEEYELVQ 
       710        720        730        740        750
VISEDKELVI PDSANVFYAM NSQVNFDFIL RKKNSMEEQV KLRSRTSLTL 
       760 
PRTAKRGCWS NRHSKITL

Length:768

Mass (Da):86,701

Last modified:October 1, 2000 - v1

Checksum:ⁱ5EE4AF6D5E0C2386

GO

Isoform B (identifier: Q9NZL6-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-9: MKLLWQAKM → MEVKPVGEPTQEVSKFKLSTKVESTGHWLVEDHVRIWEVLKTEE

« Hide

        10         20         30         40         50
MEVKPVGEPT QEVSKFKLST KVESTGHWLV EDHVRIWEVL KTEESSIQDW 
        60         70         80         90        100
GEEVEEGAVY HVTLKRVQIQ QAANKGARWL GVEGDQLPPG HTVSQYETCK 
       110        120        130        140        150
IRTIKAGTLE KLVENLLTAF GDNDFTYISI FLSTYRGFAS TKEVLELLLD 
       160        170        180        190        200
RYGNLTSPNC EEDGSQSSSE SKMVIRNAIA SILRAWLDQC AEDFREPPHF 
       210        220        230        240        250
PCLQKLLDYL TRMMPGSDPE RRAQNLLEQF QKQEVETDNG LPNTISFSLE 
       260        270        280        290        300
EEEELEGGES AEFTCFSEDL VAEQLTYMDA QLFKKVVPHH CLGCIWSRRD 
       310        320        330        340        350
KKENKHLAPT IRATISQFNT LTKCVVSTIL GGKELKTQQR AKIIEKWINI 
       360        370        380        390        400
AHECRLLKNF SSLRAIVSAL QSNSIYRLKK TWAAVPRDRM LMFEELSDIF 
       410        420        430        440        450
SDHNNHLTSR ELLMKEGTSK FANLDSSVKE NQKRTQRRLQ LQKDMGVMQG 
       460        470        480        490        500
TVPYLGTFLT DLTMLDTALQ DYIEGGLINF EKRRREFEVI AQIKLLQSAC 
       510        520        530        540        550
NSYCMTPDQK FIQWFQRQQL LTEEESYALS CEIEAAADAS TTSPKPRKSM 
       560        570        580        590        600
VKRLSLLFLG SDMITSPTPT KEQPKSTASG SSGESMDSVS VSSCESNHSE 
       610        620        630        640        650
AEEGSITPMD TPDEPQKKLS ESSSSCSSIH SMDTNSSGMS SLINPLSSPP 
       660        670        680        690        700
SCNNNPKIHK RSVSVTSITS TVLPPVYNQQ NEDTCIIRIS VEDNNGNMYK 
       710        720        730        740        750
SIMLTSQDKT PAVIQRAMLK HNLDSDPAEE YELVQVISED KELVIPDSAN 
       760        770        780        790        800
VFYAMNSQVN FDFILRKKNS MEEQVKLRSR TSLTLPRTAK RGCWSNRHSK 

ITL

Show »

Length:803

Mass (Da):90,690

Checksum:ⁱ296B9ED349ECBC1C

GO

Sequence cautionⁱ

The sequence BAA76803 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	15	W → G (PubMed:17974005).Curated	1
Sequence conflictⁱ	687	N → Y (PubMed:17974005).Curated	1
Sequence conflictⁱ	761	N → Y in AAF67281 (PubMed:10760592).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_035823	174	Y → S in a breast cancer sample; somatic mutation. 1 Publication		1
Natural variantⁱVAR_035824	699	V → M in a breast cancer sample; somatic mutation. 1 Publication		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_001824	1 – 9	MKLLWQAKM → MEVKPVGEPTQEVSKFKLST KVESTGHWLVEDHVRIWEVL KTEE in isoform B. 2 Publications		9

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF186779 mRNA Translation: AAF67280.1 AF186780 mRNA Translation: AAF67281.1 AF186798 AF186797 Genomic DNA Translation: AAG14400.1 AF186798 AF186797 Genomic DNA Translation: AAG14401.1 AB023176 mRNA Translation: BAA76803.1 Different initiation. AL590422 Genomic DNA No translation available. AL592299 Genomic DNA No translation available. CH471067 Genomic DNA Translation: EAW91166.1 CH471067 Genomic DNA Translation: EAW91167.1 BC136591 mRNA Translation: AAI36592.1 AL080117 mRNA Translation: CAB45716.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS1359.1 [Q9NZL6-2] CCDS72992.1 [Q9NZL6-1]
PIRⁱ	T12453
NCBI Reference Sequences More...RefSeqⁱ	NP_001284598.1, NM_001297669.1 NP_001284599.1, NM_001297670.1 NP_001284600.1, NM_001297671.1 [Q9NZL6-1] NP_001284601.1, NM_001297672.1 NP_055964.3, NM_015149.4 [Q9NZL6-2] XP_011507641.1, XM_011509339.2 [Q9NZL6-2]
UniGeneⁱ	Hs.497148

Genome annotation databases

Ensemblⁱ	ENST00000304685; ENSP00000303192; ENSG00000143344 [Q9NZL6-2] ENST00000360851; ENSP00000354097; ENSG00000143344 [Q9NZL6-1]
GeneIDⁱ	23179
KEGGⁱ	hsa:23179
UCSC genome browser More...UCSCⁱ	uc001gqm.4 human [Q9NZL6-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Protein	Similar proteins		Species	Score	Length	Source
Q9NZL6	Ral guanine nucleotide dissociation stimulator-like 1	)	MOUSE		768	UniRef90_Q9NZL6
Uncharacterized protein		FELCA		873
Ral guanine nucleotide dissociation stimulator-like 1		CALJA		803
RGL1 isoform 1		PANTR		803
Uncharacterized protein		PANPA		803
+261

Protein	Similar proteins		Species	Score	Length	Source
Q9NZL6	Ral guanine nucleotide dissociation stimulator-like 1	)	MOUSE		768	UniRef50_Q9NZL6
Ral guanine nucleotide dissociation stimulator-like 1		DANRE		804
Uncharacterized protein		FELCA		873
Ral guanine nucleotide dissociation stimulator-like 1		FUKDA		803
Ral guanine nucleotide dissociation stimulator-like 1		MYODS		803
+580

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF186779 mRNA Translation: AAF67280.1 AF186780 mRNA Translation: AAF67281.1 AF186798 AF186797 Genomic DNA Translation: AAG14400.1 AF186798 AF186797 Genomic DNA Translation: AAG14401.1 AB023176 mRNA Translation: BAA76803.1 Different initiation. AL590422 Genomic DNA No translation available. AL592299 Genomic DNA No translation available. CH471067 Genomic DNA Translation: EAW91166.1 CH471067 Genomic DNA Translation: EAW91167.1 BC136591 mRNA Translation: AAI36592.1 AL080117 mRNA Translation: CAB45716.1
CCDSⁱ	CCDS1359.1 [Q9NZL6-2] CCDS72992.1 [Q9NZL6-1]
PIRⁱ	T12453
RefSeqⁱ	NP_001284598.1, NM_001297669.1 NP_001284599.1, NM_001297670.1 NP_001284600.1, NM_001297671.1 [Q9NZL6-1] NP_001284601.1, NM_001297672.1 NP_055964.3, NM_015149.4 [Q9NZL6-2] XP_011507641.1, XM_011509339.2 [Q9NZL6-2]
UniGeneⁱ	Hs.497148

3D structure databases

ProteinModelPortalⁱ	Q9NZL6
SMRⁱ	Q9NZL6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	116791, 11 interactors
DIPⁱ	DIP-31372N
IntActⁱ	Q9NZL6, 2 interactors
STRINGⁱ	9606.ENSP00000303192

PTM databases

iPTMnetⁱ	Q9NZL6
PhosphoSitePlusⁱ	Q9NZL6

Polymorphism and mutation databases

BioMutaⁱ	RGL1
DMDMⁱ	14548230

Proteomic databases

EPDⁱ	Q9NZL6
PaxDbⁱ	Q9NZL6
PeptideAtlasⁱ	Q9NZL6
PRIDEⁱ	Q9NZL6
ProteomicsDBⁱ	83430 83431 [Q9NZL6-2]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000304685; ENSP00000303192; ENSG00000143344 [Q9NZL6-2] ENST00000360851; ENSP00000354097; ENSG00000143344 [Q9NZL6-1]
GeneIDⁱ	23179
KEGGⁱ	hsa:23179
UCSCⁱ	uc001gqm.4 human [Q9NZL6-1]

Organism-specific databases

CTDⁱ	23179
DisGeNETⁱ	23179
EuPathDBⁱ	HostDB:ENSG00000143344.15
GeneCardsⁱ	RGL1
H-InvDBⁱ	HIX0001411
HGNCⁱ	HGNC:30281 RGL1
HPAⁱ	HPA019788
MIMⁱ	605667 gene
neXtProtⁱ	NX_Q9NZL6
OpenTargetsⁱ	ENSG00000143344
PharmGKBⁱ	PA134934636
HUGEⁱ	Search...
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3629 Eukaryota ENOG410ZUT5 LUCA
GeneTreeⁱ	ENSGT00910000143985
HOGENOMⁱ	HOG000231592
HOVERGENⁱ	HBG005864
InParanoidⁱ	Q9NZL6
KOⁱ	K17635
OMAⁱ	QSAPDFY
OrthoDBⁱ	EOG091G0761
PhylomeDBⁱ	Q9NZL6
TreeFamⁱ	TF315204

Enzyme and pathway databases

Reactomeⁱ	R-HSA-1989781 PPARA activates gene expression

Reactomeⁱ

R-HSA-1989781 PPARA activates gene expression

Miscellaneous databases

ChiTaRSⁱ	RGL1 human
GenomeRNAiⁱ	23179
Protein Ontology More...PROⁱ	PR:Q9NZL6
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000143344 Expressed in 235 organ(s), highest expression level in endothelial cell
CleanExⁱ	HS_RGL1
Genevisibleⁱ	Q9NZL6 HS

Family and domain databases

CDDⁱ	cd00155 RasGEF, 1 hit cd06224 REM, 1 hit
Gene3Dⁱ	1.10.840.10, 1 hit
InterProⁱ	View protein in InterPro IPR000159 RA_dom IPR008937 Ras-like_GEF IPR000651 Ras-like_Gua-exchang_fac_N IPR019804 Ras_G-nucl-exch_fac_CS IPR023578 Ras_GEF_dom_sf IPR001895 RASGEF_cat_dom IPR036964 RASGEF_cat_dom_sf IPR030748 RGL1 IPR029071 Ubiquitin-like_domsf
PANTHERⁱ	PTHR23113 PTHR23113, 1 hit PTHR23113:SF199 PTHR23113:SF199, 1 hit
Pfamⁱ	View protein in Pfam PF00788 RA, 1 hit PF00617 RasGEF, 1 hit PF00618 RasGEF_N, 1 hit
SMARTⁱ	View protein in SMART SM00314 RA, 1 hit SM00147 RasGEF, 1 hit SM00229 RasGEFN, 1 hit
SUPFAMⁱ	SSF48366 SSF48366, 1 hit SSF54236 SSF54236, 1 hit
PROSITEⁱ	View protein in PROSITE PS50200 RA, 1 hit PS00720 RASGEF, 1 hit PS50009 RASGEF_CAT, 1 hit PS50212 RASGEF_NTER, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RGL1_HUMAN
Accessionⁱ	Q9NZL6Primary (citable) accession number: Q9NZL6 Secondary accession number(s): Q5SXQ2 Q9Y2G6
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 20, 2001
	Last sequence update:	October 1, 2000
	Last modified:	November 7, 2018
	This is version 160 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

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UniProtKB - Q9NZL6 (RGL1_HUMAN)

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Ral guanine nucleotide dissociation stimulator-like 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytosol

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Compositional bias

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ