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UniProtKB - Q9NZD2 (GLTP_HUMAN)

Protein

Glycolipid transfer protein

Gene

GLTP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.4 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei140Glycolipid1 Publication1
Binding sitei207Glycolipid1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ceramide 1-phosphate binding Source: GO_Central
  • ceramide 1-phosphate transporter activity Source: GO_Central
  • glycolipid binding Source: HGNC
  • glycolipid transporter activity Source: Reactome
  • identical protein binding Source: IntAct
  • intermembrane lipid transfer activity Source: BHF-UCL
  • lipid binding Source: HGNC
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-1660662 Glycosphingolipid metabolism

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glycolipid transfer protein
Short name:
GLTP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GLTP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000139433.9

Human Gene Nomenclature Database

More...HGNCi		HGNC:24867 GLTP

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		608949 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NZD2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi45I → N: 18% decrease in activity. 1 Publication1
Mutagenesisi48D → V: Significant inactivation; 15% residual activity. 1 Publication1
Mutagenesisi52N → I: Significant inactivation; 15% residual activity. 1 Publication1
Mutagenesisi55K → I: No loss of activity; 90-97% residual activity. 1 Publication1
Mutagenesisi96W → A: Almost complete inactivation; 1-3% residual activity. No effect on autophagy. 2 Publications1
Mutagenesisi96W → F: Partial inactivation; 63% residual activity. 1 Publication1
Mutagenesisi103F → S: About 25% decrease in activity. 1 Publication1
Mutagenesisi136L → R: Significant inactivation; 5% residual acti vity. 1 Publication1
Mutagenesisi140H → L: Almost complete inactivation; 1-3% residual activity. 1 Publication1
Mutagenesisi148F → S: About 50% decrease in activity. 1 Publication1
Mutagenesisi165L → R: 46% decrease in activity. 1 Publication1
Mutagenesisi183F → S: No loss of activity; 90% residual activity. 1 Publication1
Mutagenesisi207Y → L: No loss of activity; 90-97% residual activity. 1 Publication1

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000139433

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142671729

Chemistry databases

Drug and drug target database

More...DrugBanki		DB03600 Decanoic Acid
DB04465 Lactose
DB03017 Lauric Acid
DB04224 Oleic Acid
DB03203 Sphingosine

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		GLTP

Domain mapping of disease mutations (DMDM)

More...DMDMi		20138399

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001489152 – 209Glycolipid transfer proteinAdd BLAST208

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9NZD2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9NZD2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9NZD2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NZD2

PeptideAtlas

More...PeptideAtlasi		Q9NZD2

PRoteomics IDEntifications database

More...PRIDEi		Q9NZD2

ProteomicsDB human proteome resource

More...ProteomicsDBi		83375

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NZD2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NZD2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in fibroblasts (at protein level). Detected in fibroblasts and in various cancer cell lines.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000139433 Expressed in 207 organ(s), highest expression level in upper arm skin

CleanEx database of gene expression profiles

More...CleanExi		HS_GLTP

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9NZD2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NZD2 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA056461

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		119392, 6 interactors

Database of interacting proteins

More...DIPi		DIP-59418N

Protein interaction database and analysis system

More...IntActi		Q9NZD2, 2 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000315263

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1209
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1SWXX-ray1.65A1-209[»]
1SX6X-ray1.95A1-209[»]
2EUKX-ray1.85A1-209[»]
2EUMX-ray2.30A1-209[»]
2EVDX-ray2.00A1-209[»]
2EVLX-ray2.20A1-209[»]
2EVSX-ray2.20A/E1-209[»]
2EVTX-ray1.99A1-209[»]
3RICX-ray2.10A1-209[»]
3RWVX-ray1.50A/B1-209[»]
3RZNX-ray1.10A1-209[»]
3S0IX-ray1.50A1-209[»]
3S0KX-ray1.40A1-209[»]
4GH0X-ray1.35A1-209[»]
4GHPX-ray1.90A1-209[»]
4GHSX-ray3.20A/B1-209[»]
4GIXX-ray1.80A1-209[»]
4GJQX-ray2.00A/B1-209[»]
4GVTX-ray2.90A1-209[»]
4GXDX-ray2.10A1-209[»]
4GXGX-ray2.40A/B/D/E1-209[»]
4H2ZX-ray1.45A1-209[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		Q9NZD2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9NZD2

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q9NZD2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati45 – 551Add BLAST11
Repeati56 – 662Add BLAST11

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni45 – 662 X 12 AA approximate tandem repeatsAdd BLAST22
Regioni48 – 55Glycolipid binding8

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GLTP family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3221 Eukaryota
ENOG410YFEA LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155182

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000199421

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG019001

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NZD2

Identification of Orthologs from Complete Genome Data

More...OMAi		ACPYRKD

Database of Orthologous Groups

More...OrthoDBi		1628702at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NZD2

TreeFam database of animal gene trees

More...TreeFami		TF317467

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.3520.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036497 GLTP_sf
IPR014830 Glycolipid_transfer_prot_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08718 GLTP, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF110004 SSF110004, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9NZD2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALLAEHLLK PLPADKQIET GPFLEAVSHL PPFFDCLGSP VFTPIKADIS 
        60         70         80         90        100
GNITKIKAVY DTNPAKFRTL QNILEVEKEM YGAEWPKVGA TLALMWLKRG 
       110        120        130        140        150
LRFIQVFLQS ICDGERDENH PNLIRVNATK AYEMALKKYH GWIVQKIFQA 
       160        170        180        190        200
ALYAAPYKSD FLKALSKGQN VTEEECLEKI RLFLVNYTAT IDVIYEMYTQ 

MNAELNYKV
Length:209
Mass (Da):23,850
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF3DD96D702AE22CF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5GZ49F5GZ49_HUMAN
Glycolipid transfer protein isoform...
GLTP
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H0U5F5H0U5_HUMAN
Glycolipid transfer protein
GLTP
190Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YFS9H0YFS9_HUMAN
Glycolipid transfer protein
GLTP
183Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF209704 mRNA Translation: AAF33210.1
AY372530 mRNA Translation: AAR85984.1
AY372531 mRNA Translation: AAR85985.1
AY372532 mRNA Translation: AAR87373.1
AK313457 mRNA Translation: BAG36244.1
CH471054 Genomic DNA Translation: EAW97880.1
BC009932 mRNA Translation: AAH09932.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS9136.1

NCBI Reference Sequences

More...RefSeqi		NP_057517.1, NM_016433.3

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.381256

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000318348; ENSP00000315263; ENSG00000139433

Database of genes from NCBI RefSeq genomes

More...GeneIDi		51228

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:51228

UCSC genome browser

More...UCSCi		uc001tpm.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF209704 mRNA Translation: AAF33210.1
AY372530 mRNA Translation: AAR85984.1
AY372531 mRNA Translation: AAR85985.1
AY372532 mRNA Translation: AAR87373.1
AK313457 mRNA Translation: BAG36244.1
CH471054 Genomic DNA Translation: EAW97880.1
BC009932 mRNA Translation: AAH09932.1
CCDSiCCDS9136.1
RefSeqiNP_057517.1, NM_016433.3
UniGeneiHs.381256

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1SWXX-ray1.65A1-209[»]
1SX6X-ray1.95A1-209[»]
2EUKX-ray1.85A1-209[»]
2EUMX-ray2.30A1-209[»]
2EVDX-ray2.00A1-209[»]
2EVLX-ray2.20A1-209[»]
2EVSX-ray2.20A/E1-209[»]
2EVTX-ray1.99A1-209[»]
3RICX-ray2.10A1-209[»]
3RWVX-ray1.50A/B1-209[»]
3RZNX-ray1.10A1-209[»]
3S0IX-ray1.50A1-209[»]
3S0KX-ray1.40A1-209[»]
4GH0X-ray1.35A1-209[»]
4GHPX-ray1.90A1-209[»]
4GHSX-ray3.20A/B1-209[»]
4GIXX-ray1.80A1-209[»]
4GJQX-ray2.00A/B1-209[»]
4GVTX-ray2.90A1-209[»]
4GXDX-ray2.10A1-209[»]
4GXGX-ray2.40A/B/D/E1-209[»]
4H2ZX-ray1.45A1-209[»]
ProteinModelPortaliQ9NZD2
SMRiQ9NZD2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119392, 6 interactors
DIPiDIP-59418N
IntActiQ9NZD2, 2 interactors
STRINGi9606.ENSP00000315263

Chemistry databases

DrugBankiDB03600 Decanoic Acid
DB04465 Lactose
DB03017 Lauric Acid
DB04224 Oleic Acid
DB03203 Sphingosine

PTM databases

iPTMnetiQ9NZD2
PhosphoSitePlusiQ9NZD2

Polymorphism and mutation databases

BioMutaiGLTP
DMDMi20138399

Proteomic databases

EPDiQ9NZD2
jPOSTiQ9NZD2
MaxQBiQ9NZD2
PaxDbiQ9NZD2
PeptideAtlasiQ9NZD2
PRIDEiQ9NZD2
ProteomicsDBi83375

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		51228
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000318348; ENSP00000315263; ENSG00000139433
GeneIDi51228
KEGGihsa:51228
UCSCiuc001tpm.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		51228
EuPathDBiHostDB:ENSG00000139433.9

GeneCards: human genes, protein and diseases

More...GeneCardsi		GLTP
HGNCiHGNC:24867 GLTP
HPAiHPA056461
MIMi608949 gene
neXtProtiNX_Q9NZD2
OpenTargetsiENSG00000139433
PharmGKBiPA142671729

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3221 Eukaryota
ENOG410YFEA LUCA
GeneTreeiENSGT00940000155182
HOGENOMiHOG000199421
HOVERGENiHBG019001
InParanoidiQ9NZD2
OMAiACPYRKD
OrthoDBi1628702at2759
PhylomeDBiQ9NZD2
TreeFamiTF317467

Enzyme and pathway databases

ReactomeiR-HSA-1660662 Glycosphingolipid metabolism

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		GLTP human
EvolutionaryTraceiQ9NZD2

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		GLTP

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		51228

Protein Ontology

More...PROi		PR:Q9NZD2

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000139433 Expressed in 207 organ(s), highest expression level in upper arm skin
CleanExiHS_GLTP
ExpressionAtlasiQ9NZD2 baseline and differential
GenevisibleiQ9NZD2 HS

Family and domain databases

Gene3Di1.10.3520.10, 1 hit
InterProiView protein in InterPro
IPR036497 GLTP_sf
IPR014830 Glycolipid_transfer_prot_dom
PfamiView protein in Pfam
PF08718 GLTP, 1 hit
SUPFAMiSSF110004 SSF110004, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGLTP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NZD2
Secondary accession number(s): Q53Z13, Q96J68
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: January 23, 2007
Last modified: January 16, 2019
This is version 148 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
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