Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 134 (02 Dec 2020)
Sequence version 1 (01 Oct 2000)
Previous versions | rss
Add a publicationFeedback
Protein

Proline-rich protein 13

Gene

PRR13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane-induced apoptosis.1 Publication

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NZ81

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Proline-rich protein 13
Alternative name(s):
Taxane-resistance protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PRR13
Synonyms:TXR1
ORF Names:BM-041
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...
EuPathDBi
HostDB:ENSG00000205352.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24528, PRR13

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610459, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NZ81

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54458

Open Targets

More...
OpenTargetsi
ENSG00000205352

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485583

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NZ81, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PRR13

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74734721

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002439461 – 148Proline-rich protein 13Add BLAST148

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NZ81

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NZ81

PeptideAtlas

More...
PeptideAtlasi
Q9NZ81

PRoteomics IDEntifications database

More...
PRIDEi
Q9NZ81

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83339 [Q9NZ81-1]
83340 [Q9NZ81-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NZ81

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NZ81

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000205352, Expressed in blood and 118 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NZ81, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NZ81, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000205352, Tissue enhanced (blood)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
Q9NZ81
With#Exp.IntAct
AP2M1 [Q96CW1]3EBI-740924,EBI-297683
BAIAP2 [Q9UQB8]3EBI-740924,EBI-525456
CBLL2 [Q8N7E2]3EBI-740924,EBI-12196065
CELF5 [Q8N6W0]3EBI-740924,EBI-12139335
DAZAP2 [Q15038]3EBI-740924,EBI-724310
DVL3 [Q92997]3EBI-740924,EBI-739789
EWSR1 [Q01844]3EBI-740924,EBI-739737
FAM133A [Q8N9E0]3EBI-740924,EBI-10268158
FUBP1 - isoform 2 [Q96AE4-2]3EBI-740924,EBI-12121668
H2BC15 [U3KQK0]3EBI-740924,EBI-12142839
hCG_1744368 [A0A024RA76]3EBI-740924,EBI-10180729
IL16 - isoform 2 [Q14005-2]3EBI-740924,EBI-17178971
KHDC4 - isoform 4 [Q7Z7F0-4]3EBI-740924,EBI-9089060
KLHL12 [Q53G59]7EBI-740924,EBI-740929
KRTAP10-5 [P60370]3EBI-740924,EBI-10172150
KRTAP10-7 [P60409]3EBI-740924,EBI-10172290
KRTAP10-8 [P60410]6EBI-740924,EBI-10171774
KRTAP15-1 [Q3LI76]3EBI-740924,EBI-11992140
KRTAP19-5 [Q3LI72]5EBI-740924,EBI-1048945
KRTAP19-7 [Q3SYF9]3EBI-740924,EBI-10241353
KRTAP21-2 [Q3LI59]3EBI-740924,EBI-18395721
KRTAP6-1 [Q3LI64]5EBI-740924,EBI-12111050
KRTAP6-2 [Q3LI66]6EBI-740924,EBI-11962084
KRTAP7-1 [Q8IUC3]3EBI-740924,EBI-18394498
KRTAP8-1 [Q8IUC2]3EBI-740924,EBI-10261141
LGALS3 [P17931]4EBI-740924,EBI-1170392
LGALS3 [Q6NVH9]3EBI-740924,EBI-10187804
LNX1 [Q8TBB1]4EBI-740924,EBI-739832
MSX2 [P35548]3EBI-740924,EBI-6447480
OTX1 [P32242]3EBI-740924,EBI-740446
PEX5 [P50542]3EBI-740924,EBI-597835
PLSCR1 [O15162]3EBI-740924,EBI-740019
PSMA3 [P25788]3EBI-740924,EBI-348380
PSME3 [P61289]6EBI-740924,EBI-355546
RBM47 [A0AV96]3EBI-740924,EBI-2823850
SDCBP [O00560]3EBI-740924,EBI-727004
SDCBP2 [Q9H190]7EBI-740924,EBI-742426
SMUG1 - isoform 2 [Q53HV7-2]3EBI-740924,EBI-12275818
SREK1IP1 [Q8N9Q2]3EBI-740924,EBI-10268630
SRI [P30626]3EBI-740924,EBI-750459
TIAL1 - isoform 2 [Q01085-2]3EBI-740924,EBI-11064654
TNFAIP8 [O95379]6EBI-740924,EBI-1049336
TRIP13 [Q15645]3EBI-740924,EBI-358993
VAC14 [Q08AM6]6EBI-740924,EBI-2107455
ZCCHC10 [Q8TBK6]4EBI-740924,EBI-597063

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
119965, 52 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NZ81, 50 interactors

Molecular INTeraction database

More...
MINTi
Q9NZ81

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000412064

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NZ81, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NZ81

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi4 – 101Pro-richAdd BLAST98
Compositional biasi117 – 135His-richAdd BLAST19
Compositional biasi136 – 147Ser-richAdd BLAST12

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R4RR, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111608

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_2432475_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NZ81

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NZ81-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MWNPNAGQPG PNPYPPNIGC PGGSNPAHPP PINPPFPPGP CPPPPGAPHG
60 70 80 90 100
NPAFPPGGPP HPVPQPGYPG CQPLGPYPPP YPPPAPGIPP VNPLAPGMVG
110 120 130 140
PAVIVDKKMQ KKMKKAHKKM HKHQKHHKYH KHGKHSSSSS SSSSSDSD
Length:148
Mass (Da):15,385
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i56BFEE6A15935A2E
GO
Isoform 2 (identifier: Q9NZ81-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     7-56: Missing.

Show »
Length:98
Mass (Da):10,531
Checksum:i69D555BE51FC4EE2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VRX0F8VRX0_HUMAN
Proline-rich protein 13
PRR13
116Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VU40F8VU40_HUMAN
Proline-rich protein 13
PRR13
151Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VZP4F8VZP4_HUMAN
Proline-rich protein 13
PRR13
162Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VP70F8VP70_HUMAN
Proline-rich protein 13
PRR13
52Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W1R5F8W1R5_HUMAN
Proline-rich protein 13
PRR13
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VWB5F8VWB5_HUMAN
Proline-rich protein 13
PRR13
58Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti56P → S in CAG38490 (Ref. 2) Curated1
Sequence conflicti73P → L in AAH66943 (PubMed:15489334).Curated1
Sequence conflicti137S → P in CAE45980 (PubMed:17974005).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0243947 – 56Missing in isoform 2. 1 PublicationAdd BLAST50

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF217517 mRNA Translation: AAF67628.1
CR533459 mRNA Translation: CAG38490.1
BX640962 mRNA Translation: CAE45980.1
CH471054 Genomic DNA Translation: EAW96703.1
BC014257 mRNA Translation: AAH14257.1
BC016064 mRNA Translation: AAH16064.1
BC066943 mRNA Translation: AAH66943.1
BK005847 mRNA Translation: DAA05782.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS31811.1 [Q9NZ81-2]
CCDS44899.1 [Q9NZ81-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001005354.1, NM_001005354.2 [Q9NZ81-2]
NP_060927.1, NM_018457.3 [Q9NZ81-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000379786; ENSP00000369112; ENSG00000205352 [Q9NZ81-2]
ENST00000429243; ENSP00000412064; ENSG00000205352 [Q9NZ81-1]
ENST00000549135; ENSP00000447777; ENSG00000205352 [Q9NZ81-1]
ENST00000549581; ENSP00000448153; ENSG00000205352 [Q9NZ81-2]
ENST00000549924; ENSP00000448761; ENSG00000205352 [Q9NZ81-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54458

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54458

UCSC genome browser

More...
UCSCi
uc001scy.5, human [Q9NZ81-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF217517 mRNA Translation: AAF67628.1
CR533459 mRNA Translation: CAG38490.1
BX640962 mRNA Translation: CAE45980.1
CH471054 Genomic DNA Translation: EAW96703.1
BC014257 mRNA Translation: AAH14257.1
BC016064 mRNA Translation: AAH16064.1
BC066943 mRNA Translation: AAH66943.1
BK005847 mRNA Translation: DAA05782.1
CCDSiCCDS31811.1 [Q9NZ81-2]
CCDS44899.1 [Q9NZ81-1]
RefSeqiNP_001005354.1, NM_001005354.2 [Q9NZ81-2]
NP_060927.1, NM_018457.3 [Q9NZ81-1]

3D structure databases

SMRiQ9NZ81
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119965, 52 interactors
IntActiQ9NZ81, 50 interactors
MINTiQ9NZ81
STRINGi9606.ENSP00000412064

PTM databases

iPTMnetiQ9NZ81
PhosphoSitePlusiQ9NZ81

Polymorphism and mutation databases

BioMutaiPRR13
DMDMi74734721

Proteomic databases

MassIVEiQ9NZ81
PaxDbiQ9NZ81
PeptideAtlasiQ9NZ81
PRIDEiQ9NZ81
ProteomicsDBi83339 [Q9NZ81-1]
83340 [Q9NZ81-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
43374, 53 antibodies

The DNASU plasmid repository

More...
DNASUi
54458

Genome annotation databases

EnsembliENST00000379786; ENSP00000369112; ENSG00000205352 [Q9NZ81-2]
ENST00000429243; ENSP00000412064; ENSG00000205352 [Q9NZ81-1]
ENST00000549135; ENSP00000447777; ENSG00000205352 [Q9NZ81-1]
ENST00000549581; ENSP00000448153; ENSG00000205352 [Q9NZ81-2]
ENST00000549924; ENSP00000448761; ENSG00000205352 [Q9NZ81-1]
GeneIDi54458
KEGGihsa:54458
UCSCiuc001scy.5, human [Q9NZ81-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54458
DisGeNETi54458
EuPathDBiHostDB:ENSG00000205352.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PRR13
HGNCiHGNC:24528, PRR13
HPAiENSG00000205352, Tissue enhanced (blood)
MIMi610459, gene
neXtProtiNX_Q9NZ81
OpenTargetsiENSG00000205352
PharmGKBiPA143485583

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502R4RR, Eukaryota
GeneTreeiENSGT00730000111608
HOGENOMiCLU_2432475_0_0_1
InParanoidiQ9NZ81

Enzyme and pathway databases

PathwayCommonsiQ9NZ81

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
54458, 209 hits in 842 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PRR13, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54458
PharosiQ9NZ81, Tdark

Protein Ontology

More...
PROi
PR:Q9NZ81
RNActiQ9NZ81, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000205352, Expressed in blood and 118 other tissues
ExpressionAtlasiQ9NZ81, baseline and differential
GenevisibleiQ9NZ81, HS

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPRR13_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NZ81
Secondary accession number(s): Q0V8U0
, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 1, 2000
Last modified: December 2, 2020
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again