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Protein

Taste receptor type 2 member 16

Gene

TAS2R16

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.2 Publications

Miscellaneous

Several bitter taste receptors are expressed in a single taste receptor cell.
Confers bitter perception of salicin to non-taster mice.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • bitter taste receptor activity Source: UniProtKB
  • G protein-coupled receptor activity Source: UniProtKB-KW

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processSensory transduction, Taste

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-418594 G alpha (i) signalling events
R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Taste receptor type 2 member 16
Short name:
T2R16
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TAS2R16
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000128519.3

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14921 TAS2R16

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604867 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NYV7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1ExtracellularSequence analysis1
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2 – 22Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini23 – 41CytoplasmicSequence analysisAdd BLAST19
Transmembranei42 – 62Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini63 – 84ExtracellularSequence analysisAdd BLAST22
Transmembranei85 – 105Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini106 – 125CytoplasmicSequence analysisAdd BLAST20
Transmembranei126 – 146Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini147 – 182ExtracellularSequence analysisAdd BLAST36
Transmembranei183 – 203Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini204 – 228CytoplasmicSequence analysisAdd BLAST25
Transmembranei229 – 249Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini250 – 257ExtracellularSequence analysis8
Transmembranei258 – 278Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini279 – 291CytoplasmicSequence analysisAdd BLAST13

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
50833

MalaCards human disease database

More...
MalaCardsi
TAS2R16
MIMi617956 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000128519

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37931

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL3309106

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TAS2R16

Domain mapping of disease mutations (DMDM)

More...
DMDMi
29839657

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000822621 – 291Taste receptor type 2 member 16Add BLAST291

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi80N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi163N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NYV7

PeptideAtlas

More...
PeptideAtlasi
Q9NYV7

PRoteomics IDEntifications database

More...
PRIDEi
Q9NYV7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
83283

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NYV7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NYV7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in a subset of gustducin-positive taste receptor cells of the tongue. Expressed in circumvallate papillae and testis (PubMed:16720576).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000128519 Expressed in 6 organ(s), highest expression level in muscle tissue

CleanEx database of gene expression profiles

More...
CleanExi
HS_TAS2R16

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NYV7 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RTP3 and RTP4.1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000249284

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
Q9NYV7

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9NYV7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IKNW Eukaryota
ENOG41119UD LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154522

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234595

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG098568

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NYV7

KEGG Orthology (KO)

More...
KOi
K08474

Identification of Orthologs from Complete Genome Data

More...
OMAi
CLQWTSM

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0HIR

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NYV7

TreeFam database of animal gene trees

More...
TreeFami
TF335891

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007960 T2R

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05296 TAS2R, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9NYV7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIPIQLTVFF MIIYVLESLT IIVQSSLIVA VLGREWLQVR RLMPVDMILI
60 70 80 90 100
SLGISRFCLQ WASMLNNFCS YFNLNYVLCN LTITWEFFNI LTFWLNSLLT
110 120 130 140 150
VFYCIKVSSF THHIFLWLRW RILRLFPWIL LGSLMITCVT IIPSAIGNYI
160 170 180 190 200
QIQLLTMEHL PRNSTVTDKL ENFHQYQFQA HTVALVIPFI LFLASTIFLM
210 220 230 240 250
ASLTKQIQHH STGHCNPSMK ARFTALRSLA VLFIVFTSYF LTILITIIGT
260 270 280 290
LFDKRCWLWV WEAFVYAFIL MHSTSLMLSS PTLKRILKGK C
Length:291
Mass (Da):33,986
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0693085F23D57D73
GO

<p>This subsection of the ‘Sequence’ section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

Genetic variation in TAS2R16 influences sensitivity to beta-glucopyranoside tasting [MIMi:617956]. Variant Asn-172 results in greater receptor activation in response to bitter beta-glucopyranoside compounds including salicin, arbutin and amygdalin compared to Lys-172 (PubMed:16051168). Variant Lys-172 may influence risk of alcohol dependence (PubMed:16385453).2 Publications

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_080835101V → M1 Publication1
Natural variantiVAR_080836114I → V1 Publication1
Natural variantiVAR_080837116L → P1 Publication1
Natural variantiVAR_080838161P → S1 Publication1
Natural variantiVAR_034539172N → K Associated with susceptibility to alcoholism. 2 PublicationsCorresponds to variant dbSNP:rs846664EnsemblClinVar.1
Natural variantiVAR_080839177Q → P1 Publication1
Natural variantiVAR_080840216N → D1 Publication1
Natural variantiVAR_080841221A → V1 Publication1
Natural variantiVAR_020205222R → H4 PublicationsCorresponds to variant dbSNP:rs860170Ensembl.1
Natural variantiVAR_080842235V → M1 Publication1
Natural variantiVAR_080843240F → V1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF227139 Genomic DNA Translation: AAF43912.1
AY724962 Genomic DNA Translation: AAU21158.1
AC004838 Genomic DNA Translation: AAP21892.1
CH236947 Genomic DNA Translation: EAL24338.1
BC095524 mRNA Translation: AAH95524.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5785.1

NCBI Reference Sequences

More...
RefSeqi
NP_058641.1, NM_016945.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.272395

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000249284; ENSP00000249284; ENSG00000128519

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
50833

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:50833

UCSC genome browser

More...
UCSCi
uc003vkl.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF227139 Genomic DNA Translation: AAF43912.1
AY724962 Genomic DNA Translation: AAU21158.1
AC004838 Genomic DNA Translation: AAP21892.1
CH236947 Genomic DNA Translation: EAL24338.1
BC095524 mRNA Translation: AAH95524.1
CCDSiCCDS5785.1
RefSeqiNP_058641.1, NM_016945.2
UniGeneiHs.272395

3D structure databases

ProteinModelPortaliQ9NYV7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000249284

Chemistry databases

BindingDBiQ9NYV7
ChEMBLiCHEMBL3309106

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

PTM databases

iPTMnetiQ9NYV7
PhosphoSitePlusiQ9NYV7

Polymorphism and mutation databases

BioMutaiTAS2R16
DMDMi29839657

Proteomic databases

PaxDbiQ9NYV7
PeptideAtlasiQ9NYV7
PRIDEiQ9NYV7
ProteomicsDBi83283

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000249284; ENSP00000249284; ENSG00000128519
GeneIDi50833
KEGGihsa:50833
UCSCiuc003vkl.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
50833
DisGeNETi50833
EuPathDBiHostDB:ENSG00000128519.3

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TAS2R16
HGNCiHGNC:14921 TAS2R16
MalaCardsiTAS2R16
MIMi604867 gene
617956 phenotype
neXtProtiNX_Q9NYV7
OpenTargetsiENSG00000128519
PharmGKBiPA37931

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IKNW Eukaryota
ENOG41119UD LUCA
GeneTreeiENSGT00940000154522
HOGENOMiHOG000234595
HOVERGENiHBG098568
InParanoidiQ9NYV7
KOiK08474
OMAiCLQWTSM
OrthoDBiEOG091G0HIR
PhylomeDBiQ9NYV7
TreeFamiTF335891

Enzyme and pathway databases

ReactomeiR-HSA-418594 G alpha (i) signalling events
R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors)

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TAS2R16

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
50833

Protein Ontology

More...
PROi
PR:Q9NYV7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000128519 Expressed in 6 organ(s), highest expression level in muscle tissue
CleanExiHS_TAS2R16
GenevisibleiQ9NYV7 HS

Family and domain databases

InterProiView protein in InterPro
IPR007960 T2R
PfamiView protein in Pfam
PF05296 TAS2R, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiT2R16_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NYV7
Secondary accession number(s): A4D0X2
, Q502V3, Q549U8, Q645W1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: October 1, 2000
Last modified: December 5, 2018
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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