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Entry version 158 (16 Oct 2019)
Sequence version 1 (01 Oct 2000)
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Protein

Tropomodulin-3

Gene

TMOD3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-390522 Striated Muscle Contraction

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tropomodulin-3
Alternative name(s):
Ubiquitous tropomodulin
Short name:
U-Tmod
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMOD3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11873 TMOD3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605112 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NYL9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
29766

Open Targets

More...
OpenTargetsi
ENSG00000138594

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36574

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NYL9

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMOD3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
23396884

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001861341 – 352Tropomodulin-3Add BLAST352

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei25PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NYL9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NYL9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NYL9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NYL9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NYL9

PeptideAtlas

More...
PeptideAtlasi
Q9NYL9

PRoteomics IDEntifications database

More...
PRIDEi
Q9NYL9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83252

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q9NYL9

2D gel databases

USC-OGP 2-DE database

More...
OGPi
Q9NYL9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NYL9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NYL9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9NYL9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000138594 Expressed in 210 organ(s), highest expression level in amniotic fluid

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NYL9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NYL9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA001849

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to the N-terminus of tropomyosin and to actin.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
118899, 147 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NYL9, 97 interactors

Molecular INTeraction database

More...
MINTi
Q9NYL9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000308753

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NYL9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tropomodulin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3735 Eukaryota
ENOG410YAHM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158280

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000261624

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NYL9

KEGG Orthology (KO)

More...
KOi
K10370

Identification of Orthologs from Complete Genome Data

More...
OMAi
NTHVKHF

Database of Orthologous Groups

More...
OrthoDBi
1025132at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NYL9

TreeFam database of animal gene trees

More...
TreeFami
TF315841

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032675 LRR_dom_sf
IPR004934 TMOD
IPR030133 TMOD3

The PANTHER Classification System

More...
PANTHERi
PTHR10901 PTHR10901, 1 hit
PTHR10901:SF18 PTHR10901:SF18, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03250 Tropomodulin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9NYL9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALPFRKDLE KYKDLDEDEL LGNLSETELK QLETVLDDLD PENALLPAGF
60 70 80 90 100
RQKNQTSKST TGPFDREHLL SYLEKEALEH KDREDYVPYT GEKKGKIFIP
110 120 130 140 150
KQKPVQTFTE EKVSLDPELE EALTSASDTE LCDLAAILGM HNLITNTKFC
160 170 180 190 200
NIMGSSNGVD QEHFSNVVKG EKILPVFDEP PNPTNVEESL KRTKENDAHL
210 220 230 240 250
VEVNLNNIKN IPIPTLKDFA KALETNTHVK CFSLAATRSN DPVATAFAEM
260 270 280 290 300
LKVNKTLKSL NVESNFITGV GILALIDALR DNETLAELKI DNQRQQLGTA
310 320 330 340 350
VELEMAKMLE ENTNILKFGY QFTQQGPRTR AANAITKNND LVRKRRVEGD

HQ
Length:352
Mass (Da):39,595
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8B7F2122C1BE9855
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YNJ8H0YNJ8_HUMAN
Tropomodulin-3
TMOD3
213Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YKU1H0YKU1_HUMAN
Tropomodulin-3
TMOD3
187Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YNU8H0YNU8_HUMAN
Tropomodulin-3
TMOD3
33Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti27T → S in AAF31670 (PubMed:10662549).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF237631 mRNA Translation: AAF45299.1
AF177171 mRNA Translation: AAF31670.1
AK312569 mRNA Translation: BAG35464.1
BC020542 mRNA Translation: AAH20542.1
AL137543 mRNA Translation: CAB70801.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10145.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T46384

NCBI Reference Sequences

More...
RefSeqi
NP_055362.1, NM_014547.4
XP_016877576.1, XM_017022087.1
XP_016877577.1, XM_017022088.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000308580; ENSP00000308753; ENSG00000138594

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
29766

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:29766

UCSC genome browser

More...
UCSCi
uc002abn.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF237631 mRNA Translation: AAF45299.1
AF177171 mRNA Translation: AAF31670.1
AK312569 mRNA Translation: BAG35464.1
BC020542 mRNA Translation: AAH20542.1
AL137543 mRNA Translation: CAB70801.1
CCDSiCCDS10145.1
PIRiT46384
RefSeqiNP_055362.1, NM_014547.4
XP_016877576.1, XM_017022087.1
XP_016877577.1, XM_017022088.1

3D structure databases

SMRiQ9NYL9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi118899, 147 interactors
IntActiQ9NYL9, 97 interactors
MINTiQ9NYL9
STRINGi9606.ENSP00000308753

PTM databases

iPTMnetiQ9NYL9
PhosphoSitePlusiQ9NYL9
SwissPalmiQ9NYL9

Polymorphism and mutation databases

BioMutaiTMOD3
DMDMi23396884

2D gel databases

OGPiQ9NYL9

Proteomic databases

EPDiQ9NYL9
jPOSTiQ9NYL9
MassIVEiQ9NYL9
MaxQBiQ9NYL9
PaxDbiQ9NYL9
PeptideAtlasiQ9NYL9
PRIDEiQ9NYL9
ProteomicsDBi83252
TopDownProteomicsiQ9NYL9

Genome annotation databases

EnsembliENST00000308580; ENSP00000308753; ENSG00000138594
GeneIDi29766
KEGGihsa:29766
UCSCiuc002abn.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
29766
DisGeNETi29766

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMOD3
HGNCiHGNC:11873 TMOD3
HPAiHPA001849
MIMi605112 gene
neXtProtiNX_Q9NYL9
OpenTargetsiENSG00000138594
PharmGKBiPA36574

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3735 Eukaryota
ENOG410YAHM LUCA
GeneTreeiENSGT00940000158280
HOGENOMiHOG000261624
InParanoidiQ9NYL9
KOiK10370
OMAiNTHVKHF
OrthoDBi1025132at2759
PhylomeDBiQ9NYL9
TreeFamiTF315841

Enzyme and pathway databases

ReactomeiR-HSA-390522 Striated Muscle Contraction

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TMOD3 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TMOD3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
29766
PharosiQ9NYL9

Protein Ontology

More...
PROi
PR:Q9NYL9

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000138594 Expressed in 210 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiQ9NYL9 baseline and differential
GenevisibleiQ9NYL9 HS

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR032675 LRR_dom_sf
IPR004934 TMOD
IPR030133 TMOD3
PANTHERiPTHR10901 PTHR10901, 1 hit
PTHR10901:SF18 PTHR10901:SF18, 1 hit
PfamiView protein in Pfam
PF03250 Tropomodulin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMOD3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NYL9
Secondary accession number(s): B2R6G7, Q9NT43, Q9NZR0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: October 1, 2000
Last modified: October 16, 2019
This is version 158 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
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