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Protein

Bcl-2-associated transcription factor 1

Gene

BCLAF1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.1 Publication

GO - Molecular functioni

  • DNA binding Source: MGI
  • RNA binding Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Bcl-2-associated transcription factor 1
Short name:
Btf
Alternative name(s):
BCLAF1 and THRAP3 family member 1
Gene namesi
Name:BCLAF1
Synonyms:BTF, KIAA0164
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000029363.15
HGNCiHGNC:16863 BCLAF1
MIMi612588 gene
neXtProtiNX_Q9NYF8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

DisGeNETi9774
OpenTargetsiENSG00000029363
PharmGKBiPA134868035

Polymorphism and mutation databases

BioMutaiBCLAF1
DMDMi47605556

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000648881 – 920Bcl-2-associated transcription factor 1Add BLAST920

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei102PhosphoserineCombined sources1
Modified residuei104PhosphoserineCombined sources1
Modified residuei152N6-acetyllysineCombined sources1
Modified residuei177PhosphoserineCombined sources1 Publication1
Modified residuei181PhosphoserineCombined sources1
Cross-linki188Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei196PhosphoserineCombined sources1
Modified residuei198PhosphoserineCombined sources1
Modified residuei219PhosphotyrosineCombined sources1
Modified residuei222PhosphoserineCombined sources1
Modified residuei259PhosphoserineCombined sources1
Modified residuei262PhosphoserineCombined sources1
Modified residuei264PhosphoserineCombined sources1
Modified residuei268PhosphoserineCombined sources1 Publication1
Modified residuei284PhosphotyrosineCombined sources1
Modified residuei285PhosphoserineCombined sources1
Modified residuei290PhosphoserineCombined sources1 Publication1
Modified residuei297PhosphoserineCombined sources1
Modified residuei300PhosphoserineCombined sources1
Modified residuei315PhosphoserineCombined sources1
Modified residuei332N6-acetyllysine; alternateBy similarity1
Cross-linki332Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei341PhosphothreonineCombined sources1
Modified residuei355PhosphothreonineCombined sources1
Modified residuei383PhosphotyrosineCombined sources1
Modified residuei385PhosphoserineCombined sources1
Modified residuei389PhosphoserineCombined sources1
Modified residuei397PhosphoserineCombined sources1
Modified residuei402PhosphothreonineCombined sources1
Cross-linki413Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei421N6-acetyllysine; alternateBy similarity1
Cross-linki421Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei422PhosphoserineCombined sources1
Modified residuei427PhosphoserineCombined sources1
Modified residuei431PhosphothreonineCombined sources1
Modified residuei437N6-acetyllysine; alternateCombined sources1
Cross-linki437Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei450PhosphoserineCombined sources1
Cross-linki457Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki462Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei472PhosphoserineCombined sources1
Modified residuei475N6-acetyllysineBy similarity1
Cross-linki491Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki492Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei494PhosphothreonineCombined sources1
Modified residuei496PhosphoserineCombined sources1
Cross-linki501Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei502PhosphoserineCombined sources1
Modified residuei512PhosphoserineCombined sources1 Publication1
Modified residuei525PhosphoserineCombined sources1
Modified residuei531PhosphoserineCombined sources1 Publication1
Cross-linki536Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki548Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki550Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei559PhosphoserineCombined sources1
Modified residuei564PhosphoserineCombined sources1
Modified residuei566PhosphothreonineCombined sources1
Cross-linki567Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei578PhosphoserineCombined sources1
Cross-linki580Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linki580Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Cross-linki593Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki599Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki622Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei648PhosphoserineCombined sources1
Modified residuei658PhosphoserineCombined sources1 Publication1
Modified residuei660PhosphoserineCombined sources1
Modified residuei661PhosphothreonineCombined sources1
Cross-linki676Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei690PhosphoserineCombined sources1
Modified residuei760PhosphoserineCombined sources1
Cross-linki778Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki784Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei803CitrullineBy similarity1
Modified residuei809Omega-N-methylarginineCombined sources1
Cross-linki831Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linki831Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Cross-linki911Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Isoform 4 (identifier: Q9NYF8-4)
Modified residuei339PhosphoserineCombined sources1

Post-translational modificationi

Citrullinated by PADI4.By similarity

Keywords - PTMi

Acetylation, Citrullination, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9NYF8
MaxQBiQ9NYF8
PaxDbiQ9NYF8
PeptideAtlasiQ9NYF8
PRIDEiQ9NYF8
ProteomicsDBi83221
83222 [Q9NYF8-2]
83223 [Q9NYF8-3]
83224 [Q9NYF8-4]

PTM databases

iPTMnetiQ9NYF8
PhosphoSitePlusiQ9NYF8
SwissPalmiQ9NYF8

Expressioni

Tissue specificityi

Ubiquitous.

Gene expression databases

BgeeiENSG00000029363 Expressed in 242 organ(s), highest expression level in substantia nigra
CleanExiHS_BCLAF1
ExpressionAtlasiQ9NYF8 baseline and differential
GenevisibleiQ9NYF8 HS

Organism-specific databases

HPAiHPA006484
HPA006669
HPA027770

Interactioni

Subunit structurei

Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA. Component of the SNARP complex which consists at least of SNIP1, SNW1, THRAP3, BCLAF1 and PNN. Component of a MACOM-like complex, named WTAP complex, composed of WTAP, ZC3H13, CBLL1, KIAA1429, RBM15, BCLAF1 and THRAP3.3 Publications

Binary interactionsi

Protein-protein interaction databases

BioGridi115118, 120 interactors
IntActiQ9NYF8, 75 interactors
MINTiQ9NYF8
STRINGi9606.ENSP00000435210

Structurei

3D structure databases

ProteinModelPortaliQ9NYF8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi141 – 148Poly-Ser8
Compositional biasi749 – 763Poly-SerAdd BLAST15

Sequence similaritiesi

Belongs to the BCLAF1/THRAP3 family.Curated

Phylogenomic databases

eggNOGiENOG410IJCD Eukaryota
ENOG4110X68 LUCA
GeneTreeiENSGT00530000063211
HOVERGENiHBG050681
InParanoidiQ9NYF8
KOiK13087
OMAiTSHRNTE
OrthoDBiEOG091G03HU
PhylomeDBiQ9NYF8
TreeFamiTF335939

Family and domain databases

InterProiView protein in InterPro
IPR026668 Bcl-2_assoc_TF1
IPR029199 THRAP3_BCLAF1
PANTHERiPTHR15268 PTHR15268, 1 hit
PTHR15268:SF4 PTHR15268:SF4, 1 hit
PfamiView protein in Pfam
PF15440 THRAP3_BCLAF1, 1 hit

Sequences (4+)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NYF8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGRSNSRSHS SRSKSRSQSS SRSRSRSHSR KKRYSSRSRS RTYSRSRSRD
60 70 80 90 100
RMYSRDYRRD YRNNRGMRRP YGYRGRGRGY YQGGGGRYHR GGYRPVWNRR
110 120 130 140 150
HSRSPRRGRS RSRSPKRRSV SSQRSRSRSR RSYRSSRSPR SSSSRSSSPY
160 170 180 190 200
SKSPVSKRRG SQEKQTKKAE GEPQEESPLK SKSQEEPKDT FEHDPSESID
210 220 230 240 250
EFNKSSATSG DIWPGLSAYD NSPRSPHSPS PIATPPSQSS SCSDAPMLST
260 270 280 290 300
VHSAKNTPSQ HSHSIQHSPE RSGSGSVGNG SSRYSPSQNS PIHHIPSRRS
310 320 330 340 350
PAKTIAPQNA PRDESRGRSS FYPDGGDQET AKTGKFLKRF TDEESRVFLL
360 370 380 390 400
DRGNTRDKEA SKEKGSEKGR AEGEWEDQEA LDYFSDKESG KQKFNDSEGD
410 420 430 440 450
DTEETEDYRQ FRKSVLADQG KSFATASHRN TEEEGLKYKS KVSLKGNRES
460 470 480 490 500
DGFREEKNYK LKETGYVVER PSTTKDKHKE EDKNSERITV KKETQSPEQV
510 520 530 540 550
KSEKLKDLFD YSPPLHKNLD AREKSTFREE SPLRIKMIAS DSHRPEVKLK
560 570 580 590 600
MAPVPLDDSN RPASLTKDRL LASTLVHSVK KEQEFRSIFD HIKLPQASKS
610 620 630 640 650
TSESFIQHIV SLVHHVKEQY FKSAAMTLNE RFTSYQKATE EHSTRQKSPE
660 670 680 690 700
IHRRIDISPS TLRKHTRLAG EERVFKEENQ KGDKKLRCDS ADLRHDIDRR
710 720 730 740 750
RKERSKERGD SKGSRESSGS RKQEKTPKDY KEYKSYKDDS KHKREQDHSR
760 770 780 790 800
SSSSSASPSS PSSREEKESK KEREEEFKTH HEMKEYSGFA GVSRPRGTFF
810 820 830 840 850
RIRGRGRARG VFAGTNTGPN NSNTTFQKRP KEEEWDPEYT PKSKKYFLHD
860 870 880 890 900
DRDDGVDYWA KRGRGRGTFQ RGRGRFNFKK SGSSPKWTHD KYQGDGIVED
910 920
EEETMENNEE KKDRRKEEKE
Length:920
Mass (Da):106,122
Last modified:May 24, 2004 - v2
Checksum:i8892B98E54F52C20
GO
Isoform 2 (identifier: Q9NYF8-2) [UniParc]FASTAAdd to basket
Also known as: Btf-l

The sequence of this isoform differs from the canonical sequence as follows:
     35-36: Missing.

Show »
Length:918
Mass (Da):105,948
Checksum:i8DD27EC0EC8FBFC5
GO
Isoform 3 (identifier: Q9NYF8-3) [UniParc]FASTAAdd to basket
Also known as: Btf-s, BP-1

The sequence of this isoform differs from the canonical sequence as follows:
     35-36: Missing.
     800-848: Missing.

Show »
Length:869
Mass (Da):100,232
Checksum:i6A11356844C6EF40
GO
Isoform 4 (identifier: Q9NYF8-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     339-511: Missing.

Show »
Length:747
Mass (Da):85,937
Checksum:i85CDAF9B406FAE0F
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PK91E9PK91_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
871Annotation score:
E9PK09E9PK09_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
725Annotation score:
E9PKI6E9PKI6_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
752Annotation score:
H0YF63H0YF63_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
126Annotation score:
H0YF14H0YF14_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
187Annotation score:
E9PJA7E9PJA7_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
467Annotation score:
E9PQN2E9PQN2_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
750Annotation score:
H0YF00H0YF00_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
118Annotation score:
A0A1W2PQ43A0A1W2PQ43_HUMAN
Bcl-2-associated transcription fact...
BCLAF1
703Annotation score:

Sequence cautioni

The sequence AAH47687 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH47887 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH56894 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH63846 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence BAA11481 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti4S → A in AAF64304 (PubMed:10330179).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05959166G → A. Corresponds to variant dbSNP:rs9942517Ensembl.1
Natural variantiVAR_050692209S → C. Corresponds to variant dbSNP:rs6940018Ensembl.1
Natural variantiVAR_050693459Y → D. Corresponds to variant dbSNP:rs1967446Ensembl.1
Natural variantiVAR_050694461L → H. Corresponds to variant dbSNP:rs1967445Ensembl.1
Natural variantiVAR_050695629N → S. Corresponds to variant dbSNP:rs7381749Ensembl.1
Natural variantiVAR_050696875R → C. Corresponds to variant dbSNP:rs34541670Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_01036935 – 36Missing in isoform 2 and isoform 3. 2 Publications2
Alternative sequenceiVSP_010371339 – 511Missing in isoform 4. 1 PublicationAdd BLAST173
Alternative sequenceiVSP_010370800 – 848Missing in isoform 3. 1 PublicationAdd BLAST49

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF249273 mRNA Translation: AAF64304.1
D79986 mRNA Translation: BAA11481.2 Different initiation.
AL121713 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47950.1
CH471051 Genomic DNA Translation: EAW47951.1
BC047687 mRNA Translation: AAH47687.1 Sequence problems.
BC047887 mRNA Translation: AAH47887.1 Sequence problems.
BC056894 mRNA Translation: AAH56894.1 Sequence problems.
BC063846 mRNA Translation: AAH63846.1 Sequence problems.
BC132780 mRNA Translation: AAI32781.1
BC144281 mRNA Translation: AAI44282.1
CCDSiCCDS47485.1 [Q9NYF8-4]
CCDS47486.1 [Q9NYF8-3]
CCDS5177.1 [Q9NYF8-1]
CCDS75525.1 [Q9NYF8-2]
RefSeqiNP_001070908.1, NM_001077440.1 [Q9NYF8-3]
NP_001070909.1, NM_001077441.1 [Q9NYF8-4]
NP_001287967.1, NM_001301038.1 [Q9NYF8-2]
NP_055554.1, NM_014739.2 [Q9NYF8-1]
UniGeneiHs.486542

Genome annotation databases

EnsembliENST00000353331; ENSP00000229446; ENSG00000029363 [Q9NYF8-3]
ENST00000392348; ENSP00000376159; ENSG00000029363 [Q9NYF8-3]
ENST00000527759; ENSP00000434826; ENSG00000029363 [Q9NYF8-2]
ENST00000530767; ENSP00000436501; ENSG00000029363 [Q9NYF8-4]
ENST00000531224; ENSP00000435210; ENSG00000029363 [Q9NYF8-1]
GeneIDi9774
KEGGihsa:9774
UCSCiuc003qgw.2 human [Q9NYF8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Cross-referencesi

Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF249273 mRNA Translation: AAF64304.1
D79986 mRNA Translation: BAA11481.2 Different initiation.
AL121713 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47950.1
CH471051 Genomic DNA Translation: EAW47951.1
BC047687 mRNA Translation: AAH47687.1 Sequence problems.
BC047887 mRNA Translation: AAH47887.1 Sequence problems.
BC056894 mRNA Translation: AAH56894.1 Sequence problems.
BC063846 mRNA Translation: AAH63846.1 Sequence problems.
BC132780 mRNA Translation: AAI32781.1
BC144281 mRNA Translation: AAI44282.1
CCDSiCCDS47485.1 [Q9NYF8-4]
CCDS47486.1 [Q9NYF8-3]
CCDS5177.1 [Q9NYF8-1]
CCDS75525.1 [Q9NYF8-2]
RefSeqiNP_001070908.1, NM_001077440.1 [Q9NYF8-3]
NP_001070909.1, NM_001077441.1 [Q9NYF8-4]
NP_001287967.1, NM_001301038.1 [Q9NYF8-2]
NP_055554.1, NM_014739.2 [Q9NYF8-1]
UniGeneiHs.486542

3D structure databases

ProteinModelPortaliQ9NYF8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115118, 120 interactors
IntActiQ9NYF8, 75 interactors
MINTiQ9NYF8
STRINGi9606.ENSP00000435210

PTM databases

iPTMnetiQ9NYF8
PhosphoSitePlusiQ9NYF8
SwissPalmiQ9NYF8

Polymorphism and mutation databases

BioMutaiBCLAF1
DMDMi47605556

Proteomic databases

EPDiQ9NYF8
MaxQBiQ9NYF8
PaxDbiQ9NYF8
PeptideAtlasiQ9NYF8
PRIDEiQ9NYF8
ProteomicsDBi83221
83222 [Q9NYF8-2]
83223 [Q9NYF8-3]
83224 [Q9NYF8-4]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000353331; ENSP00000229446; ENSG00000029363 [Q9NYF8-3]
ENST00000392348; ENSP00000376159; ENSG00000029363 [Q9NYF8-3]
ENST00000527759; ENSP00000434826; ENSG00000029363 [Q9NYF8-2]
ENST00000530767; ENSP00000436501; ENSG00000029363 [Q9NYF8-4]
ENST00000531224; ENSP00000435210; ENSG00000029363 [Q9NYF8-1]
GeneIDi9774
KEGGihsa:9774
UCSCiuc003qgw.2 human [Q9NYF8-1]

Organism-specific databases

CTDi9774
DisGeNETi9774
EuPathDBiHostDB:ENSG00000029363.15
GeneCardsiBCLAF1
HGNCiHGNC:16863 BCLAF1
HPAiHPA006484
HPA006669
HPA027770
MIMi612588 gene
neXtProtiNX_Q9NYF8
OpenTargetsiENSG00000029363
PharmGKBiPA134868035
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJCD Eukaryota
ENOG4110X68 LUCA
GeneTreeiENSGT00530000063211
HOVERGENiHBG050681
InParanoidiQ9NYF8
KOiK13087
OMAiTSHRNTE
OrthoDBiEOG091G03HU
PhylomeDBiQ9NYF8
TreeFamiTF335939

Miscellaneous databases

ChiTaRSiBCLAF1 human
GeneWikiiBCLAF1
GenomeRNAii9774
PROiPR:Q9NYF8
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000029363 Expressed in 242 organ(s), highest expression level in substantia nigra
CleanExiHS_BCLAF1
ExpressionAtlasiQ9NYF8 baseline and differential
GenevisibleiQ9NYF8 HS

Family and domain databases

InterProiView protein in InterPro
IPR026668 Bcl-2_assoc_TF1
IPR029199 THRAP3_BCLAF1
PANTHERiPTHR15268 PTHR15268, 1 hit
PTHR15268:SF4 PTHR15268:SF4, 1 hit
PfamiView protein in Pfam
PF15440 THRAP3_BCLAF1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiBCLF1_HUMAN
AccessioniPrimary (citable) accession number: Q9NYF8
Secondary accession number(s): A2RU75
, B7ZM58, E1P586, Q14673, Q86WU6, Q86WY0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: September 12, 2018
This is version 166 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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