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Entry version 119 (16 Oct 2019)
Sequence version 2 (18 May 2010)
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Protein

SID1 transmembrane family member 1

Gene

SIDT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.79.1.2 the cholesterol uptake protein (chup) or double stranded rna uptake family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SID1 transmembrane family member 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SIDT1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25967 SIDT1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606816 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NXL6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini20 – 309ExtracellularSequence analysisAdd BLAST290
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei310 – 330HelicalSequence analysisAdd BLAST21
Topological domaini331 – 442CytoplasmicSequence analysisAdd BLAST112
Transmembranei443 – 463HelicalSequence analysisAdd BLAST21
Topological domaini464 – 494ExtracellularSequence analysisAdd BLAST31
Transmembranei495 – 515HelicalSequence analysisAdd BLAST21
Topological domaini516 – 541CytoplasmicSequence analysisAdd BLAST26
Transmembranei542 – 562HelicalSequence analysisAdd BLAST21
Topological domaini563 – 572ExtracellularSequence analysis10
Transmembranei573 – 590HelicalSequence analysisAdd BLAST18
Topological domaini591 – 600CytoplasmicSequence analysis10
Transmembranei601 – 621HelicalSequence analysisAdd BLAST21
Topological domaini622 – 626ExtracellularSequence analysis5
Transmembranei627 – 647HelicalSequence analysisAdd BLAST21
Topological domaini648 – 683CytoplasmicSequence analysisAdd BLAST36
Transmembranei684 – 704HelicalSequence analysisAdd BLAST21
Topological domaini705 – 710ExtracellularSequence analysis6
Transmembranei711 – 731HelicalSequence analysisAdd BLAST21
Topological domaini732 – 741CytoplasmicSequence analysis10
Transmembranei742 – 762HelicalSequence analysisAdd BLAST21
Topological domaini763 – 791ExtracellularSequence analysisAdd BLAST29
Transmembranei792 – 812HelicalSequence analysisAdd BLAST21
Topological domaini813 – 827CytoplasmicSequence analysisAdd BLAST15

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54847

Open Targets

More...
OpenTargetsi
ENSG00000072858

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134923837

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NXL6

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SIDT1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296452905

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003257520 – 827SID1 transmembrane family member 1Add BLAST808

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi57N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi67N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi83N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi136N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi282N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi471N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi567N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi764N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NXL6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NXL6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NXL6

PeptideAtlas

More...
PeptideAtlasi
Q9NXL6

PRoteomics IDEntifications database

More...
PRIDEi
Q9NXL6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83110 [Q9NXL6-1]
83111 [Q9NXL6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NXL6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NXL6

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9NXL6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000072858 Expressed in 166 organ(s), highest expression level in right hemisphere of cerebellum

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NXL6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035862

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9NXL6, 2 interactors

Molecular INTeraction database

More...
MINTi
Q9NXL6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000264852

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SID1 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IF6Z Eukaryota
ENOG410XPBN LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010091

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000020635

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NXL6

Identification of Orthologs from Complete Genome Data

More...
OMAi
QPGQVNA

Database of Orthologous Groups

More...
OrthoDBi
139174at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NXL6

TreeFam database of animal gene trees

More...
TreeFami
TF313076

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025958 SID1_TM_fam

The PANTHER Classification System

More...
PANTHERi
PTHR12185 PTHR12185, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13965 SID-1_RNA_chan, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9NXL6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRGCLRLALL CALPWLLLAA SPGHPAKSPR QPPAPRRDPF DAARGADFDH
60 70 80 90 100
VYSGVVNLST ENIYSFNYTS QPDQVTAVRV YVNSSSENLN YPVLVVVRQQ
110 120 130 140 150
KEVLSWQVPL LFQGLYQRSY NYQEVSRTLC PSEATNETGP LQQLIFVDVA
160 170 180 190 200
SMAPLGAQYK LLVTKLKHFQ LRTNVAFHFT ASPSQPQYFL YKFPKDVDSV
210 220 230 240 250
IIKVVSEMAY PCSVVSVQNI MCPVYDLDHN VEFNGVYQSM TKKAAITLQK
260 270 280 290 300
KDFPGEQFFV VFVIKPEDYA CGGSFFIQEK ENQTWNLQRK KNLEVTIVPS
310 320 330 340 350
IKESVYVKSS LFSVFIFLSF YLGCLLVGFV HYLRFQRKSI DGSFGSNDGS
360 370 380 390 400
GNMVASHPIA ASTPEGSNYG TIDESSSSPG RQMSSSDGGP PGQSDTDSSV
410 420 430 440 450
EESDFDTMPD IESDKNIIRT KMFLYLSDLS RKDRRIVSKK YKIYFWNIIT
460 470 480 490 500
IAVFYALPVI QLVITYQTVV NVTGNQDICY YNFLCAHPLG VLSAFNNILS
510 520 530 540 550
NLGHVLLGFL FLLIVLRRDI LHRRALEAKD IFAVEYGIPK HFGLFYAMGI
560 570 580 590 600
ALMMEGVLSA CYHVCPNYSN FQFDTSFMYM IAGLCMLKLY QTRHPDINAS
610 620 630 640 650
AYSAYASFAV VIMVTVLGVV FGKNDVWFWV IFSAIHVLAS LALSTQIYYM
660 670 680 690 700
GRFKIDLGIF RRAAMVFYTD CIQQCSRPLY MDRMVLLVVG NLVNWSFALF
710 720 730 740 750
GLIYRPRDFA SYMLGIFICN LLLYLAFYII MKLRSSEKVL PVPLFCIVAT
760 770 780 790 800
AVMWAAALYF FFQNLSSWEG TPAESREKNR ECILLDFFDD HDIWHFLSAT
810 820
ALFFSFLVLL TLDDDLDVVR RDQIPVF
Length:827
Mass (Da):93,839
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE7C383DF74378B8C
GO
Isoform 2 (identifier: Q9NXL6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     655-655: I → IDVSDT

Note: No experimental confirmation available.
Show »
Length:832
Mass (Da):94,356
Checksum:iB0709610421A9D01
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti572Q → R in BAA90994 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0617933G → S. Corresponds to variant dbSNP:rs9879313Ensembl.1
Natural variantiVAR_05718478V → M. Corresponds to variant dbSNP:rs2271496Ensembl.1
Natural variantiVAR_057185363T → I. Corresponds to variant dbSNP:rs33990195Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_039174655I → IDVSDT in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK000181 mRNA Translation: BAA90994.1
AC055740 Genomic DNA No translation available.
AC112128 Genomic DNA No translation available.
BC117222 mRNA Translation: AAI17223.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2974.1 [Q9NXL6-1]
CCDS77790.1 [Q9NXL6-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001295279.1, NM_001308350.1 [Q9NXL6-2]
NP_060169.2, NM_017699.2 [Q9NXL6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000264852; ENSP00000264852; ENSG00000072858 [Q9NXL6-1]
ENST00000393830; ENSP00000377416; ENSG00000072858 [Q9NXL6-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54847

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54847

UCSC genome browser

More...
UCSCi
uc003eak.4 human [Q9NXL6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000181 mRNA Translation: BAA90994.1
AC055740 Genomic DNA No translation available.
AC112128 Genomic DNA No translation available.
BC117222 mRNA Translation: AAI17223.1
CCDSiCCDS2974.1 [Q9NXL6-1]
CCDS77790.1 [Q9NXL6-2]
RefSeqiNP_001295279.1, NM_001308350.1 [Q9NXL6-2]
NP_060169.2, NM_017699.2 [Q9NXL6-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9NXL6, 2 interactors
MINTiQ9NXL6
STRINGi9606.ENSP00000264852

Protein family/group databases

TCDBi1.A.79.1.2 the cholesterol uptake protein (chup) or double stranded rna uptake family

PTM databases

iPTMnetiQ9NXL6
PhosphoSitePlusiQ9NXL6
SwissPalmiQ9NXL6

Polymorphism and mutation databases

BioMutaiSIDT1
DMDMi296452905

Proteomic databases

jPOSTiQ9NXL6
MassIVEiQ9NXL6
PaxDbiQ9NXL6
PeptideAtlasiQ9NXL6
PRIDEiQ9NXL6
ProteomicsDBi83110 [Q9NXL6-1]
83111 [Q9NXL6-2]

Genome annotation databases

EnsembliENST00000264852; ENSP00000264852; ENSG00000072858 [Q9NXL6-1]
ENST00000393830; ENSP00000377416; ENSG00000072858 [Q9NXL6-2]
GeneIDi54847
KEGGihsa:54847
UCSCiuc003eak.4 human [Q9NXL6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54847
DisGeNETi54847

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SIDT1
HGNCiHGNC:25967 SIDT1
HPAiHPA035862
MIMi606816 gene
neXtProtiNX_Q9NXL6
OpenTargetsiENSG00000072858
PharmGKBiPA134923837

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IF6Z Eukaryota
ENOG410XPBN LUCA
GeneTreeiENSGT00390000010091
HOGENOMiHOG000020635
InParanoidiQ9NXL6
OMAiQPGQVNA
OrthoDBi139174at2759
PhylomeDBiQ9NXL6
TreeFamiTF313076

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SIDT1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54847
PharosiQ9NXL6

Protein Ontology

More...
PROi
PR:Q9NXL6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000072858 Expressed in 166 organ(s), highest expression level in right hemisphere of cerebellum
GenevisibleiQ9NXL6 HS

Family and domain databases

InterProiView protein in InterPro
IPR025958 SID1_TM_fam
PANTHERiPTHR12185 PTHR12185, 1 hit
PfamiView protein in Pfam
PF13965 SID-1_RNA_chan, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSIDT1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NXL6
Secondary accession number(s): Q17RR4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: May 18, 2010
Last modified: October 16, 2019
This is version 119 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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