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Entry version 136 (12 Aug 2020)
Sequence version 2 (03 Apr 2007)
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Protein

Membrane progestin receptor gamma

Gene

PAQR5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167).1 Publication1 Publication

Miscellaneous

Non-classical progesterone receptors involved in extranuclear signaling are classified in 2 groups: the class II progestin and adipoQ receptor (PAQR) family (also called mPRs) (PAQR5, PAQR6, PAQR7, PAQR8 and PAQR9) and the b5-like heme/steroid-binding protein family (also called MAPRs) (PGRMC1, PGRMC2, NENF and CYB5D2).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Receptor
Biological processDifferentiation, Oogenesis
LigandLipid-binding, Steroid-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NXK6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Membrane progestin receptor gamma1 Publication
Short name:
mPR gamma1 Publication
Alternative name(s):
Membrane progesterone P4 receptor gamma1 Publication
Membrane progesterone receptor gamma1 Publication
Progesterone and adipoQ receptor family member 5
Progestin and adipoQ receptor family member 51 Publication
Progestin and adipoQ receptor family member V
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PAQR5Imported
Synonyms:MPRG
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000137819.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29645, PAQR5

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
607781, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NXK6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 51CytoplasmicSequence analysisAdd BLAST51
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei52 – 72Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini73 – 80ExtracellularSequence analysis8
Transmembranei81 – 101Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini102 – 113CytoplasmicSequence analysisAdd BLAST12
Transmembranei114 – 134Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini135 – 141ExtracellularSequence analysis7
Transmembranei142 – 162Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini163 – 186CytoplasmicSequence analysisAdd BLAST24
Transmembranei187 – 207Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini208 – 253ExtracellularSequence analysisAdd BLAST46
Transmembranei254 – 274Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini275 – 294CytoplasmicSequence analysisAdd BLAST20
Transmembranei295 – 315Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini316 – 330ExtracellularSequence analysisAdd BLAST15

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54852

Open Targets

More...
OpenTargetsi
ENSG00000137819

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671199

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NXK6, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PAQR5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
143811422

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002188431 – 330Membrane progestin receptor gammaAdd BLAST330

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NXK6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NXK6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NXK6

PeptideAtlas

More...
PeptideAtlasi
Q9NXK6

PRoteomics IDEntifications database

More...
PRIDEi
Q9NXK6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83106

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NXK6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NXK6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the brain, lung, kidney, colon, adrenal and lung.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000137819, Expressed in adult mammalian kidney and 123 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NXK6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NXK6, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000137819, Tissue enhanced (kidney)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120202, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NXK6, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000378803

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NXK6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NXK6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ADIPOR family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0748, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158844

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_052356_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NXK6

Identification of Orthologs from Complete Genome Data

More...
OMAi
GLCKMLR

Database of Orthologous Groups

More...
OrthoDBi
1524940at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NXK6

TreeFam database of animal gene trees

More...
TreeFami
TF319738

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004254, AdipoR/HlyIII-related

The PANTHER Classification System

More...
PANTHERi
PTHR20855, PTHR20855, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03006, HlyIII, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9NXK6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLSLKLPRLF SIDQIPQVFH EQGILFGYRH PQSSATACIL SLFQMTNETL
60 70 80 90 100
NIWTHLLPFW FFAWRFVTAL YMTDIKNDSY SWPMLVYMCT SCVYPLVSSC
110 120 130 140 150
AHTFSSMSKN ARHICYFLDY GAVNLFSLGS AIAYSAYTFP DALMCTTFHD
160 170 180 190 200
YYVALAVLNT ILSTGLSCYS RFLEIQKPRL CKVIRVLAFA YPYTWDSLPI
210 220 230 240 250
FYRLFLFPGE SAQNEATSYH QKHMIMTLLA SFLYSAHLPE RLAPGRFDYI
260 270 280 290 300
GHSHQLFHVC VILATHMQME AILLDKTLRK EWLLATSKPF SFSQIAGAIL
310 320 330
LCIIFSLSNI IYFSAALYRI PKPELHKKET
Length:330
Mass (Da):38,014
Last modified:April 3, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFA0AF2785EAAFFE8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YL06H0YL06_HUMAN
Membrane progestin receptor gamma
PAQR5
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti175I → V in AAR08371 (PubMed:16044242).Curated1
Sequence conflicti175I → V in BAA91004 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03143624I → T1 PublicationCorresponds to variant dbSNP:rs17853893Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY424283 mRNA Translation: AAR08371.1
AK000197 mRNA Translation: BAA91004.1
BC039234 mRNA Translation: AAH39234.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10232.1

NCBI Reference Sequences

More...
RefSeqi
NP_001098024.1, NM_001104554.1
NP_060175.3, NM_017705.3
XP_011520022.1, XM_011521720.2
XP_011520024.1, XM_011521722.2
XP_016877849.1, XM_017022360.1
XP_016877850.1, XM_017022361.1
XP_016877851.1, XM_017022362.1
XP_016877852.1, XM_017022363.1
XP_016877853.1, XM_017022364.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000340965; ENSP00000343877; ENSG00000137819
ENST00000395407; ENSP00000378803; ENSG00000137819
ENST00000561153; ENSP00000453526; ENSG00000137819

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54852

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54852

UCSC genome browser

More...
UCSCi
uc002arz.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY424283 mRNA Translation: AAR08371.1
AK000197 mRNA Translation: BAA91004.1
BC039234 mRNA Translation: AAH39234.1
CCDSiCCDS10232.1
RefSeqiNP_001098024.1, NM_001104554.1
NP_060175.3, NM_017705.3
XP_011520022.1, XM_011521720.2
XP_011520024.1, XM_011521722.2
XP_016877849.1, XM_017022360.1
XP_016877850.1, XM_017022361.1
XP_016877851.1, XM_017022362.1
XP_016877852.1, XM_017022363.1
XP_016877853.1, XM_017022364.1

3D structure databases

SMRiQ9NXK6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120202, 4 interactors
IntActiQ9NXK6, 7 interactors
STRINGi9606.ENSP00000378803

PTM databases

iPTMnetiQ9NXK6
PhosphoSitePlusiQ9NXK6

Polymorphism and mutation databases

BioMutaiPAQR5
DMDMi143811422

Proteomic databases

MassIVEiQ9NXK6
MaxQBiQ9NXK6
PaxDbiQ9NXK6
PeptideAtlasiQ9NXK6
PRIDEiQ9NXK6
ProteomicsDBi83106

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
13981, 99 antibodies

The DNASU plasmid repository

More...
DNASUi
54852

Genome annotation databases

EnsembliENST00000340965; ENSP00000343877; ENSG00000137819
ENST00000395407; ENSP00000378803; ENSG00000137819
ENST00000561153; ENSP00000453526; ENSG00000137819
GeneIDi54852
KEGGihsa:54852
UCSCiuc002arz.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54852
DisGeNETi54852
EuPathDBiHostDB:ENSG00000137819.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PAQR5
HGNCiHGNC:29645, PAQR5
HPAiENSG00000137819, Tissue enhanced (kidney)
MIMi607781, gene
neXtProtiNX_Q9NXK6
OpenTargetsiENSG00000137819
PharmGKBiPA142671199

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0748, Eukaryota
GeneTreeiENSGT00940000158844
HOGENOMiCLU_052356_1_0_1
InParanoidiQ9NXK6
OMAiGLCKMLR
OrthoDBi1524940at2759
PhylomeDBiQ9NXK6
TreeFamiTF319738

Enzyme and pathway databases

PathwayCommonsiQ9NXK6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
54852, 4 hits in 872 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PAQR5, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54852
PharosiQ9NXK6, Tbio

Protein Ontology

More...
PROi
PR:Q9NXK6
RNActiQ9NXK6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000137819, Expressed in adult mammalian kidney and 123 other tissues
ExpressionAtlasiQ9NXK6, baseline and differential
GenevisibleiQ9NXK6, HS

Family and domain databases

InterProiView protein in InterPro
IPR004254, AdipoR/HlyIII-related
PANTHERiPTHR20855, PTHR20855, 1 hit
PfamiView protein in Pfam
PF03006, HlyIII, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPAQR5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NXK6
Secondary accession number(s): Q8IXU2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: April 3, 2007
Last modified: August 12, 2020
This is version 136 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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