Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - Q9NXF1 (TEX10_HUMAN)

Entry version 176 (23 Feb 2022)
Sequence version 2 (19 Jul 2005)
Previous versions | rss
Add a publicationFeedback
Protein

Testis-expressed protein 10

Gene

TEX10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859).

Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211).

2 Publications

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9NXF1

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9NXF1

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q9NXF1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Testis-expressed protein 10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TEX10
ORF Names:L18, Nbla10363
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25988, TEX10

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NXF1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000136891

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		54881

Open Targets

More...OpenTargetsi		ENSG00000136891

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134991964

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9NXF1, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TEX10

Domain mapping of disease mutations (DMDM)

More...DMDMi		71153593

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000724911 – 929Testis-expressed protein 10Add BLAST929

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei29PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9NXF1

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9NXF1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9NXF1

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9NXF1

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NXF1

PeptideAtlas

More...PeptideAtlasi		Q9NXF1

PRoteomics IDEntifications database

More...PRIDEi		Q9NXF1

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		83086 [Q9NXF1-1]
83087 [Q9NXF1-2]

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...SWISS-2DPAGEi		Q9NXF1

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9NXF1, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NXF1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NXF1

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9NXF1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000136891, Expressed in ventricular zone and 218 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9NXF1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NXF1, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000136891, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10.

Component of the 5FMC complex, at least composed of PELP1, LAS1L, TEX10, WDR18 and SENP3; the complex interacts with methylated CHTOP and ZNF148.

Component of the PELP1 complex, composed of at least PELP1, TEX10 and WDR18. The complex interacts with pre-60S ribosome particles (PubMed:21326211).

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120229, 132 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9NXF1

Protein interaction database and analysis system

More...IntActi		Q9NXF1, 52 interactors

Molecular INTeraction database

More...MINTi		Q9NXF1

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000364037

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9NXF1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati99 – 137HEATAdd BLAST39

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the IPI1/TEX10 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2149, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182992

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_014208_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NXF1

Identification of Orthologs from Complete Genome Data

More...OMAi		EADGDWL

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NXF1

TreeFam database of animal gene trees

More...TreeFami		TF318197

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR021133, HEAT_type_2
IPR024679, Ipi1_N
IPR037947, TEX10/Ipi1

The PANTHER Classification System

More...PANTHERi		PTHR16056:SF2, PTHR16056:SF2, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12333, Ipi1_N, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50077, HEAT_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NXF1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTKKRKRQHD FQKVKLKVGK KKPKLQNATP TNFKTKTIHL PEQLKEDGTL 
        60         70         80         90        100
PTNNRKLNIK DLLSQMHHYN AGVKQSALLG LKDLLSQYPF IIDAHLSNIL 
       110        120        130        140        150
SEVTAVFTDK DANVRLAAVQ LLQFLAPKIR AEQISPFFPL VSAHLSSAMT 
       160        170        180        190        200
HITEGIQEDS LKVLDILLEQ YPALITGRSS ILLKNFVELI SHQQLSKGLI 
       210        220        230        240        250
NRDRSQSWIL SVNPNRRLTS QQWRLKVLVR LSKFLQALAD GSSRLRESEG 
       260        270        280        290        300
LQEQKENPHA TSNSIFINWK EHANDQQHIQ VYENGGSQPN VSSQFRLRYL 
       310        320        330        340        350
VGGLSGVDEG LSSTENLKGF IEIIIPLLIE CWVEAVPPQL ATPVGNGIER 
       360        370        380        390        400
EPLQVMQQVL NIISLLWKLS KQQDETHKLE SWLRKNYLID FKHHFMSRFP 
       410        420        430        440        450
YVLKEITKHK RKEPNKSIKH CTVLSNNIDH LLLNLTLSDI MVSLANASTL 
       460        470        480        490        500
QKDCSWIEMI RKFVTETLED GSRLNSKQLN RLLGVSWRLM QIQPNREDTE 
       510        520        530        540        550
TLIKAVYTLY QQRGLILPVR TLLLKFFSKI YQTEELRSCR FRYRSKVLSR 
       560        570        580        590        600
WLAGLPLQLA HLGSRNPELS TQLIDIIHTA AARANKELLK SLQATALRIY 
       610        620        630        640        650
DPQEGAVVVL PADSQQRLVQ LVYFLPSLPA DLLSRLSRCC IMGRLSSSLA 
       660        670        680        690        700
AMLIGILHMR SSFSGWKYSA KDWLMSDVDY FSFLFSTLTG FSKEELTWLQ 
       710        720        730        740        750
SLRGVPHVIQ TQLSPVLLYL TDLDQFLHHW DVTEAVFHSL LVIPARSQNF 
       760        770        780        790        800
DILQSAISKH LVGLTVIPDS TAGCVFGVIC KLLDHTCVVS ETLLPFLASC 
       810        820        830        840        850
CYSLLYFLLT IEKGEAEHLR KRDKLWGVCV SILALLPRVL RLMLQSLRVN 
       860        870        880        890        900
RVGPEELPVV GQLLRLLLQH APLRTHMLTN AILVQQIIKN ITTLKSGSVQ 
       910        920 
EQWLTDLHYC FNVYITGHPQ GPSALATVY
Length:929
Mass (Da):105,674
Last modified:July 19, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2E0F8062989415BA
GO
Isoform 2 (identifier: Q9NXF1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MSRM
     822-840: Missing.

Show »
Length:913
Mass (Da):103,915
Checksum:iB1C70A0807B527C7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MSR3A0A0A0MSR3_HUMAN
Testis-expressed protein 10
TEX10
171Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti411R → G in AAH30652 (PubMed:15489334).Curated1
Sequence conflicti430H → R in AAT06748 (PubMed:15334068).Curated1
Sequence conflicti430H → R in BAA91062 (PubMed:14702039).Curated1
Sequence conflicti526F → L in AAH30652 (PubMed:15489334).Curated1
Sequence conflicti731D → E in BAB87845 (PubMed:12880961).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0437041M → MSRM in isoform 2. 1 Publication1
Alternative sequenceiVSP_043705822 – 840Missing in isoform 2. 1 PublicationAdd BLAST19

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY598337 mRNA Translation: AAT06748.1
AB060968 mRNA Translation: BAB87845.1
AK000294 mRNA Translation: BAA91062.1
AK302619 mRNA Translation: BAG63864.1
AL353805 Genomic DNA No translation available.
AL445214 Genomic DNA No translation available.
BC030652 mRNA Translation: AAH30652.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS55330.1 [Q9NXF1-2]
CCDS6748.1 [Q9NXF1-1]

NCBI Reference Sequences

More...RefSeqi		NP_001155056.1, NM_001161584.1 [Q9NXF1-2]
NP_060216.2, NM_017746.3 [Q9NXF1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000374902; ENSP00000364037; ENSG00000136891
ENST00000535814; ENSP00000444555; ENSG00000136891 [Q9NXF1-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		54881

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:54881

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000374902.9; ENSP00000364037.4; NM_017746.4; NP_060216.2

UCSC genome browser

More...UCSCi		uc004bas.4, human [Q9NXF1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY598337 mRNA Translation: AAT06748.1
AB060968 mRNA Translation: BAB87845.1
AK000294 mRNA Translation: BAA91062.1
AK302619 mRNA Translation: BAG63864.1
AL353805 Genomic DNA No translation available.
AL445214 Genomic DNA No translation available.
BC030652 mRNA Translation: AAH30652.1
CCDSiCCDS55330.1 [Q9NXF1-2]
CCDS6748.1 [Q9NXF1-1]
RefSeqiNP_001155056.1, NM_001161584.1 [Q9NXF1-2]
NP_060216.2, NM_017746.3 [Q9NXF1-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120229, 132 interactors
CORUMiQ9NXF1
IntActiQ9NXF1, 52 interactors
MINTiQ9NXF1
STRINGi9606.ENSP00000364037

PTM databases

GlyGeniQ9NXF1, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ9NXF1
PhosphoSitePlusiQ9NXF1
SwissPalmiQ9NXF1

Genetic variation databases

BioMutaiTEX10
DMDMi71153593

2D gel databases

SWISS-2DPAGEiQ9NXF1

Proteomic databases

EPDiQ9NXF1
jPOSTiQ9NXF1
MassIVEiQ9NXF1
MaxQBiQ9NXF1
PaxDbiQ9NXF1
PeptideAtlasiQ9NXF1
PRIDEiQ9NXF1
ProteomicsDBi83086 [Q9NXF1-1]
83087 [Q9NXF1-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		43979, 29 antibodies from 13 providers

The DNASU plasmid repository

More...DNASUi		54881

Genome annotation databases

EnsembliENST00000374902; ENSP00000364037; ENSG00000136891
ENST00000535814; ENSP00000444555; ENSG00000136891 [Q9NXF1-2]
GeneIDi54881
KEGGihsa:54881
MANE-SelectiENST00000374902.9; ENSP00000364037.4; NM_017746.4; NP_060216.2
UCSCiuc004bas.4, human [Q9NXF1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54881
DisGeNETi54881

GeneCards: human genes, protein and diseases

More...GeneCardsi		TEX10
HGNCiHGNC:25988, TEX10
HPAiENSG00000136891, Low tissue specificity
neXtProtiNX_Q9NXF1
OpenTargetsiENSG00000136891
PharmGKBiPA134991964
VEuPathDBiHostDB:ENSG00000136891

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2149, Eukaryota
GeneTreeiENSGT00950000182992
HOGENOMiCLU_014208_0_0_1
InParanoidiQ9NXF1
OMAiEADGDWL
PhylomeDBiQ9NXF1
TreeFamiTF318197

Enzyme and pathway databases

PathwayCommonsiQ9NXF1
ReactomeiR-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
SignaLinkiQ9NXF1
SIGNORiQ9NXF1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		54881, 602 hits in 1060 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TEX10, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		TEX10

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		54881
PharosiQ9NXF1, Tdark

Protein Ontology

More...PROi		PR:Q9NXF1
RNActiQ9NXF1, protein

Gene expression databases

BgeeiENSG00000136891, Expressed in ventricular zone and 218 other tissues
ExpressionAtlasiQ9NXF1, baseline and differential
GenevisibleiQ9NXF1, HS

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR021133, HEAT_type_2
IPR024679, Ipi1_N
IPR037947, TEX10/Ipi1
PANTHERiPTHR16056:SF2, PTHR16056:SF2, 1 hit
PfamiView protein in Pfam
PF12333, Ipi1_N, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50077, HEAT_REPEAT, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTEX10_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NXF1
Secondary accession number(s): B4DYV2
, Q5T722, Q5T723, Q8NCN8, Q8TDY0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: February 23, 2022
This is version 176 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again