Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - Q9NX36 (DJC28_HUMAN)

Entry version 151 (23 Feb 2022)
Sequence version 2 (19 Sep 2002)
Previous versions | rss
Add a publicationFeedback
Protein

DnaJ homolog subfamily C member 28

Gene

DNAJC28

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May have a role in protein folding or as a chaperone.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9NX36

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9NX36

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DnaJ homolog subfamily C member 28
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DNAJC28
Synonyms:C21orf55, C21orf78
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:1297, DNAJC28

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NX36

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000177692

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000177692

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162383922

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9NX36, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		DNAJC28

Domain mapping of disease mutations (DMDM)

More...DMDMi		23396536

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000711391 – 388DnaJ homolog subfamily C member 28Add BLAST388

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei347PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9NX36

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9NX36

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9NX36

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NX36

PeptideAtlas

More...PeptideAtlasi		Q9NX36

PRoteomics IDEntifications database

More...PRIDEi		Q9NX36

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		83029

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NX36

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NX36

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the fetal and adult brain, testis, uterus, spleen and liver.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Not expressed in 8 and 10 weeks old fetuses.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000177692, Expressed in testis and 153 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NX36, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000177692, Tissue enhanced (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120283, 95 interactors

Protein interaction database and analysis system

More...IntActi		Q9NX36, 6 interactors

Molecular INTeraction database

More...MINTi		Q9NX36

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000479716

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9NX36, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9NX36

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini51 – 115JPROSITE-ProRule annotationAdd BLAST65

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili261 – 349Sequence analysisAdd BLAST89

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0568, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154065

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_040968_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NX36

Identification of Orthologs from Complete Genome Data

More...OMAi		EWISLGK

Database of Orthologous Groups

More...OrthoDBi		1394654at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NX36

TreeFam database of animal gene trees

More...TreeFami		TF323730

Family and domain databases

Conserved Domains Database

More...CDDi		cd06257, DnaJ, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.287.110, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001623, DnaJ_domain
IPR018961, DnaJ_homolog_subfam-C_membr-28
IPR036869, J_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00226, DnaJ, 1 hit
PF09350, DUF1992, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00271, DnaJ, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46565, SSF46565, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50076, DNAJ_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9NX36-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNTMYVMMAQ ILRSHLIKAT VIPNRVKMLP YFGIIRNRMM STHKSKKKIR 
        60         70         80         90        100
EYYRLLNVEE GCSADEVRES FHKLAKQYHP DSGSNTADSA TFIRIEKAYR 
       110        120        130        140        150
KVLSHVIEQT NASQSKGEEE EDVEKFKYKT PQHRHYLSFE GIGFGTPTQR 
       160        170        180        190        200
EKHYRQFRAD RAAEQVMEYQ KQKLQSQYFP DSVIVKNIRQ SKQQKITQAI 
       210        220        230        240        250
ERLVEDLIQE SMAKGDFDNL SGKGKPLKKF SDCSYIDPMT HNLNRILIDN 
       260        270        280        290        300
GYQPEWILKQ KEISDTIEQL REAILVSRKK LGNPMTPTEK KQWNHVCEQF 
       310        320        330        340        350
QENIRKLNKR INDFNLIVPI LTRQKVHFDA QKEIVRAQKI YETLIKTKEV 
       360        370        380 
TDRNPNNLDQ GEGEKTPEIK KGFLNWMNLW KFIKIRSF
Length:388
Mass (Da):45,806
Last modified:September 19, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCB19D9FD060031D0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti316 – 388LIVPI…KIRSF → CSHPDQAKSPF in BAA91185 (PubMed:14702039).CuratedAdd BLAST73

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF462153 mRNA Translation: AAL59618.2
AK000468 mRNA Translation: BAA91185.1
CH471079 Genomic DNA Translation: EAX09830.1
CH471079 Genomic DNA Translation: EAX09831.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS13626.1

NCBI Reference Sequences

More...RefSeqi		NP_001035282.1, NM_001040192.2
NP_001307675.1, NM_001320746.2
NP_060303.2, NM_017833.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000314399; ENSP00000320303; ENSG00000177692
ENST00000381947; ENSP00000371373; ENSG00000177692
ENST00000402202; ENSP00000385777; ENSG00000177692
ENST00000571432; ENSP00000461665; ENSG00000262911
ENST00000572540; ENSP00000461737; ENSG00000262911
ENST00000573306; ENSP00000461084; ENSG00000262911
ENST00000615701; ENSP00000483670; ENSG00000262911
ENST00000617313; ENSP00000479716; ENSG00000177692

Database of genes from NCBI RefSeq genomes

More...GeneIDi		54943

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:54943

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000381947.4; ENSP00000371373.3; NM_001040192.3; NP_001035282.1

UCSC genome browser

More...UCSCi		uc002yrv.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF462153 mRNA Translation: AAL59618.2
AK000468 mRNA Translation: BAA91185.1
CH471079 Genomic DNA Translation: EAX09830.1
CH471079 Genomic DNA Translation: EAX09831.1
CCDSiCCDS13626.1
RefSeqiNP_001035282.1, NM_001040192.2
NP_001307675.1, NM_001320746.2
NP_060303.2, NM_017833.4

3D structure databases

SMRiQ9NX36
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120283, 95 interactors
IntActiQ9NX36, 6 interactors
MINTiQ9NX36
STRINGi9606.ENSP00000479716

PTM databases

iPTMnetiQ9NX36
PhosphoSitePlusiQ9NX36

Genetic variation databases

BioMutaiDNAJC28
DMDMi23396536

Proteomic databases

EPDiQ9NX36
MassIVEiQ9NX36
MaxQBiQ9NX36
PaxDbiQ9NX36
PeptideAtlasiQ9NX36
PRIDEiQ9NX36
ProteomicsDBi83029

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		7335, 111 antibodies from 16 providers

The DNASU plasmid repository

More...DNASUi		54943

Genome annotation databases

EnsembliENST00000314399; ENSP00000320303; ENSG00000177692
ENST00000381947; ENSP00000371373; ENSG00000177692
ENST00000402202; ENSP00000385777; ENSG00000177692
ENST00000571432; ENSP00000461665; ENSG00000262911
ENST00000572540; ENSP00000461737; ENSG00000262911
ENST00000573306; ENSP00000461084; ENSG00000262911
ENST00000615701; ENSP00000483670; ENSG00000262911
ENST00000617313; ENSP00000479716; ENSG00000177692
GeneIDi54943
KEGGihsa:54943
MANE-SelectiENST00000381947.4; ENSP00000371373.3; NM_001040192.3; NP_001035282.1
UCSCiuc002yrv.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54943

GeneCards: human genes, protein and diseases

More...GeneCardsi		DNAJC28
HGNCiHGNC:1297, DNAJC28
HPAiENSG00000177692, Tissue enhanced (testis)
neXtProtiNX_Q9NX36
OpenTargetsiENSG00000177692
PharmGKBiPA162383922
VEuPathDBiHostDB:ENSG00000177692

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0568, Eukaryota
GeneTreeiENSGT00940000154065
HOGENOMiCLU_040968_1_0_1
InParanoidiQ9NX36
OMAiEWISLGK
OrthoDBi1394654at2759
PhylomeDBiQ9NX36
TreeFamiTF323730

Enzyme and pathway databases

PathwayCommonsiQ9NX36
SignaLinkiQ9NX36

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		54943, 4 hits in 1033 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		C21orf55

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		54943
PharosiQ9NX36, Tbio

Protein Ontology

More...PROi		PR:Q9NX36
RNActiQ9NX36, protein

Gene expression databases

BgeeiENSG00000177692, Expressed in testis and 153 other tissues
GenevisibleiQ9NX36, HS

Family and domain databases

CDDicd06257, DnaJ, 1 hit
Gene3Di1.10.287.110, 1 hit
InterProiView protein in InterPro
IPR001623, DnaJ_domain
IPR018961, DnaJ_homolog_subfam-C_membr-28
IPR036869, J_dom_sf
PfamiView protein in Pfam
PF00226, DnaJ, 1 hit
PF09350, DUF1992, 1 hit
SMARTiView protein in SMART
SM00271, DnaJ, 1 hit
SUPFAMiSSF46565, SSF46565, 1 hit
PROSITEiView protein in PROSITE
PS50076, DNAJ_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDJC28_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NX36
Secondary accession number(s): D3DSF2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: September 19, 2002
Last modified: February 23, 2022
This is version 151 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again