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Entry version 139 (02 Jun 2021)
Sequence version 3 (02 Nov 2010)
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Protein

Constitutive coactivator of PPAR-gamma-like protein 2

Gene

FAM120C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NX05

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Constitutive coactivator of PPAR-gamma-like protein 2
Alternative name(s):
Protein FAM120C
Tumor antigen BJ-HCC-21
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM120C
Synonyms:CXorf17
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:16949, FAM120C

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300741, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NX05

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000184083.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54954

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134932227

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NX05, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM120C

Domain mapping of disease mutations (DMDM)

More...
DMDMi
311033453

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002216281 – 1096Constitutive coactivator of PPAR-gamma-like protein 2Add BLAST1096

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei58Omega-N-methylarginineBy similarity1
Modified residuei977Omega-N-methylarginineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki1042Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Isopeptide bond, Methylation, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NX05

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NX05

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NX05

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NX05

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NX05

PeptideAtlas

More...
PeptideAtlasi
Q9NX05

PRoteomics IDEntifications database

More...
PRIDEi
Q9NX05

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83015 [Q9NX05-1]
83016 [Q9NX05-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NX05

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NX05

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at low levels in a number of tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000184083, Expressed in female gonad and 220 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NX05, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NX05, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000184083, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120292, 163 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NX05, 8 interactors

Molecular INTeraction database

More...
MINTi
Q9NX05

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000364324

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NX05, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni35 – 113DisorderedSequence analysisAdd BLAST79
Regioni508 – 579DisorderedSequence analysisAdd BLAST72
Regioni971 – 1096DisorderedSequence analysisAdd BLAST126

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi518 – 535Polar residuesSequence analysisAdd BLAST18
Compositional biasi997 – 1013Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi1014 – 1039Polar residuesSequence analysisAdd BLAST26
Compositional biasi1056 – 1076Polar residuesSequence analysisAdd BLAST21
Compositional biasi1077 – 1096Basic and acidic residuesSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQNQ, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008339_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NX05

Database of Orthologous Groups

More...
OrthoDBi
203269at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NX05

TreeFam database of animal gene trees

More...
TreeFami
TF328642

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026784, Coact_PPARg
IPR026785, Coact_PPARg-like_2
IPR029060, PIN-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR15976, PTHR15976, 1 hit
PTHR15976:SF15, PTHR15976:SF15, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF88723, SSF88723, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NX05-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGVQGFQEFL EKRCPGAVVP VDLLKLARTV SRQQQQQHLH RQLPPTAALA
60 70 80 90 100
PGAPRAARGS VPLQPPLPPA ALGAYSGGAG PIRHHHPAHH FHHHGQAQPG
110 120 130 140 150
LHPPLPPPPP PQLPGARVLV DAGSALPRLY GGYQTDWVCG GQWNAMLGYL
160 170 180 190 200
SALCQACAYP GGDGLELVVM FPGGLGKDRL AEWGRRCQAE RQTAQLIVGH
210 220 230 240 250
VGNKGTPPPR AWFLPPACLS HCVRLALIRF RVKVFQSLED HHLEVVAFFR
260 270 280 290 300
ENGFHGLLAH DSEYALYNIP SYYSSHALKL SWNGKNLTTN QFLMQEVAKQ
310 320 330 340 350
LGLKRMNFPI FAALLGNHIL PDEDLAAFHW SLLGPEHPLA SLKVRAHQLV
360 370 380 390 400
LPPCDVVIKA VSEYVSSIKD PSNLDVVGKD VFKQSQSRTE DKIERFKKAV
410 420 430 440 450
EYYSVTTKLS SLPVGPSFLG FRNNRLGNPP LPRNQVGTIS AGKPMFSHQV
460 470 480 490 500
PQKVKYPPPF PVGPNSSLLF SSHALGESHA FSEDPMLQNS PFANWAVSYD
510 520 530 540 550
SSASQFPNYL PSKASPPLGP DSSHSSSSDG DEPNGASSDH ITEAFHHQPE
560 570 580 590 600
WGNPNRDRGS WAQPVDTGVS EASLGDGEPH IPSLLSMSTR NHMDITIPPL
610 620 630 640 650
PPVAPEVLRV AEHRHRRGLM YPYIYHVLTK GEIKIPVCIE DECNMELPPA
660 670 680 690 700
ALLFRSARQY VYGVLFSLAE TQRKMERLAM RRRLPVEVPS VILKEWSAYK
710 720 730 740 750
GKSPQTPELV SALTFREWTC PNLKKLWLGK AVEDKNRRMR AFLACMKSDT
760 770 780 790 800
PSMLNPANVP THLLLMCCVL RYMVQWPGGR ILHRHELDTF LAQAVSTQLY
810 820 830 840 850
EPDRLQELKI EKLDARGIQL AALFMSGVDT ALFANDACGQ PVPWEHCCPW
860 870 880 890 900
IYFDGKLFQS KLIKAGRERV SLVELCDGQA DLATKVEKMR QSILEGVNMN
910 920 930 940 950
HPPPSALLPS PTFVPPMVPS LYPVSLYSRA MGSMPLPPQG RSRGFAGLHP
960 970 980 990 1000
IPPQGGKLEI AGMVVGQWAG SRSSRGRGSF GMQVVSVGGP GKGHGKEQTG
1010 1020 1030 1040 1050
RGSKGHKKGN KQGSSDGVSK SLELHQGRSR SQVNGNSGAL IKEEKSDHRL
1060 1070 1080 1090
PAPSQCALSR DSNECNNGNR YLPMNNREKN HLQEQKLETV AQRKED
Length:1,096
Mass (Da):120,588
Last modified:November 2, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0BF2647EF9BFE1F1
GO
Isoform 2 (identifier: Q9NX05-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     234-238: VFQSL → QAAML
     239-1096: Missing.

Show »
Length:238
Mass (Da):25,477
Checksum:iB4BCB860C18784D9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8W881F8W881_HUMAN
Constitutive coactivator of PPAR-ga...
FAM120C
895Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAM82751 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated
The sequence BAA91219 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04753882I → T4 PublicationsCorresponds to variant dbSNP:rs2495783Ensembl.1
Natural variantiVAR_062001934M → I. Corresponds to variant dbSNP:rs41304786Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_010519234 – 238VFQSL → QAAML in isoform 2. 3 Publications5
Alternative sequenceiVSP_010520239 – 1096Missing in isoform 2. 3 PublicationsAdd BLAST858

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY150025 mRNA Translation: AAO24121.1
AY121803 mRNA Translation: AAM82751.1 Sequence problems.
AK000513 mRNA Translation: BAA91219.1 Sequence problems.
AL589872 Genomic DNA No translation available.
Z84469 Genomic DNA No translation available.
BC016138 mRNA Translation: AAH16138.2
BC136413 mRNA Translation: AAI36414.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14356.1 [Q9NX05-1]
CCDS55421.1 [Q9NX05-2]

NCBI Reference Sequences

More...
RefSeqi
NP_060318.4, NM_017848.5
NP_940858.2, NM_198456.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000375180; ENSP00000364324; ENSG00000184083
ENST00000477084; ENSP00000420718; ENSG00000184083

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54954

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54954

UCSC genome browser

More...
UCSCi
uc004dsz.5, human [Q9NX05-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY150025 mRNA Translation: AAO24121.1
AY121803 mRNA Translation: AAM82751.1 Sequence problems.
AK000513 mRNA Translation: BAA91219.1 Sequence problems.
AL589872 Genomic DNA No translation available.
Z84469 Genomic DNA No translation available.
BC016138 mRNA Translation: AAH16138.2
BC136413 mRNA Translation: AAI36414.1
CCDSiCCDS14356.1 [Q9NX05-1]
CCDS55421.1 [Q9NX05-2]
RefSeqiNP_060318.4, NM_017848.5
NP_940858.2, NM_198456.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120292, 163 interactors
IntActiQ9NX05, 8 interactors
MINTiQ9NX05
STRINGi9606.ENSP00000364324

PTM databases

iPTMnetiQ9NX05
PhosphoSitePlusiQ9NX05

Genetic variation databases

BioMutaiFAM120C
DMDMi311033453

Proteomic databases

EPDiQ9NX05
jPOSTiQ9NX05
MassIVEiQ9NX05
MaxQBiQ9NX05
PaxDbiQ9NX05
PeptideAtlasiQ9NX05
PRIDEiQ9NX05
ProteomicsDBi83015 [Q9NX05-1]
83016 [Q9NX05-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
26758, 62 antibodies

The DNASU plasmid repository

More...
DNASUi
54954

Genome annotation databases

EnsembliENST00000375180; ENSP00000364324; ENSG00000184083
ENST00000477084; ENSP00000420718; ENSG00000184083
GeneIDi54954
KEGGihsa:54954
UCSCiuc004dsz.5, human [Q9NX05-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54954
DisGeNETi54954

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM120C
HGNCiHGNC:16949, FAM120C
HPAiENSG00000184083, Low tissue specificity
MIMi300741, gene
neXtProtiNX_Q9NX05
PharmGKBiPA134932227
VEuPathDBiHostDB:ENSG00000184083.11

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QQNQ, Eukaryota
HOGENOMiCLU_008339_0_0_1
InParanoidiQ9NX05
OrthoDBi203269at2759
PhylomeDBiQ9NX05
TreeFamiTF328642

Enzyme and pathway databases

PathwayCommonsiQ9NX05

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
54954, 3 hits in 623 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FAM120C, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
FAM120C_(gene)

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
54954
PharosiQ9NX05, Tbio

Protein Ontology

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PROi
PR:Q9NX05
RNActiQ9NX05, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000184083, Expressed in female gonad and 220 other tissues
ExpressionAtlasiQ9NX05, baseline and differential
GenevisibleiQ9NX05, HS

Family and domain databases

InterProiView protein in InterPro
IPR026784, Coact_PPARg
IPR026785, Coact_PPARg-like_2
IPR029060, PIN-like_dom_sf
PANTHERiPTHR15976, PTHR15976, 1 hit
PTHR15976:SF15, PTHR15976:SF15, 1 hit
SUPFAMiSSF88723, SSF88723, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF120C_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NX05
Secondary accession number(s): B2RMT7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: November 2, 2010
Last modified: June 2, 2021
This is version 139 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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