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Protein

Transmembrane protein 160

Gene

TMEM160

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 160
Gene namesi
Name:TMEM160
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000130748.6
HGNCiHGNC:26042 TMEM160
neXtProtiNX_Q9NX00

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei135 – 155HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi54958
OpenTargetsiENSG00000130748
PharmGKBiPA145147949

Polymorphism and mutation databases

BioMutaiTMEM160
DMDMi74719401

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002778101 – 188Transmembrane protein 160Add BLAST188

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei48PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9NX00
MaxQBiQ9NX00
PaxDbiQ9NX00
PeptideAtlasiQ9NX00
PRIDEiQ9NX00
ProteomicsDBi83007
TopDownProteomicsiQ9NX00

PTM databases

iPTMnetiQ9NX00
PhosphoSitePlusiQ9NX00

Expressioni

Gene expression databases

BgeeiENSG00000130748 Expressed in 198 organ(s), highest expression level in amygdala
CleanExiHS_TMEM160
GenevisibleiQ9NX00 HS

Organism-specific databases

HPAiHPA055904

Interactioni

Protein-protein interaction databases

BioGridi120296, 26 interactors
IntActiQ9NX00, 14 interactors
STRINGi9606.ENSP00000253047

Structurei

3D structure databases

ProteinModelPortaliQ9NX00
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM160 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J0AT Eukaryota
ENOG4111VX5 LUCA
GeneTreeiENSGT00390000012863
HOGENOMiHOG000154614
HOVERGENiHBG094062
InParanoidiQ9NX00
OMAiGSWWWAR
OrthoDBiEOG091G0QLF
PhylomeDBiQ9NX00
TreeFamiTF338764

Family and domain databases

InterProiView protein in InterPro
IPR026801 TMEM160
PANTHERiPTHR16236 PTHR16236, 1 hit

Sequencei

Sequence statusi: Complete.

Q9NX00-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGGWWWARA ARLARLRFRR SLLPPQRPRS GGARGSFAPG HGPRAGASPP
60 70 80 90 100
PVSELDRADA WLLRKAHETA FLSWFRNGLL ASGIGVISFM QSDMGREAAY
110 120 130 140 150
GFFLLGGLCV VWGSASYAVG LAALRGPMQL TLGGAAVGAG AVLAASLLWA
160 170 180
CAVGLYMGQL ELDVELVPED DGTASAEGPD EAGRPPPE
Length:188
Mass (Da):19,658
Last modified:October 1, 2000 - v1
Checksum:i955BE1A693B46A28
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_030600120G → S1 PublicationCorresponds to variant dbSNP:rs11083857Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000519 mRNA Translation: BAA91225.1
BC002907 mRNA Translation: AAH02907.1
CCDSiCCDS12695.1
RefSeqiNP_060324.1, NM_017854.1
UniGeneiHs.105606

Genome annotation databases

EnsembliENST00000253047; ENSP00000253047; ENSG00000130748
GeneIDi54958
KEGGihsa:54958
UCSCiuc002pfz.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000519 mRNA Translation: BAA91225.1
BC002907 mRNA Translation: AAH02907.1
CCDSiCCDS12695.1
RefSeqiNP_060324.1, NM_017854.1
UniGeneiHs.105606

3D structure databases

ProteinModelPortaliQ9NX00
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120296, 26 interactors
IntActiQ9NX00, 14 interactors
STRINGi9606.ENSP00000253047

PTM databases

iPTMnetiQ9NX00
PhosphoSitePlusiQ9NX00

Polymorphism and mutation databases

BioMutaiTMEM160
DMDMi74719401

Proteomic databases

EPDiQ9NX00
MaxQBiQ9NX00
PaxDbiQ9NX00
PeptideAtlasiQ9NX00
PRIDEiQ9NX00
ProteomicsDBi83007
TopDownProteomicsiQ9NX00

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000253047; ENSP00000253047; ENSG00000130748
GeneIDi54958
KEGGihsa:54958
UCSCiuc002pfz.4 human

Organism-specific databases

CTDi54958
DisGeNETi54958
EuPathDBiHostDB:ENSG00000130748.6
GeneCardsiTMEM160
HGNCiHGNC:26042 TMEM160
HPAiHPA055904
neXtProtiNX_Q9NX00
OpenTargetsiENSG00000130748
PharmGKBiPA145147949
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J0AT Eukaryota
ENOG4111VX5 LUCA
GeneTreeiENSGT00390000012863
HOGENOMiHOG000154614
HOVERGENiHBG094062
InParanoidiQ9NX00
OMAiGSWWWAR
OrthoDBiEOG091G0QLF
PhylomeDBiQ9NX00
TreeFamiTF338764

Miscellaneous databases

GenomeRNAii54958
PROiPR:Q9NX00

Gene expression databases

BgeeiENSG00000130748 Expressed in 198 organ(s), highest expression level in amygdala
CleanExiHS_TMEM160
GenevisibleiQ9NX00 HS

Family and domain databases

InterProiView protein in InterPro
IPR026801 TMEM160
PANTHERiPTHR16236 PTHR16236, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTM160_HUMAN
AccessioniPrimary (citable) accession number: Q9NX00
Secondary accession number(s): Q9BU41
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: October 1, 2000
Last modified: November 7, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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