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Protein

Required for meiotic nuclear division protein 1 homolog

Gene

RMND1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome (PubMed:23022098, PubMed:25604853).2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • positive regulation of mitochondrial translation Source: UniProtKB
  • translation Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Required for meiotic nuclear division protein 1 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RMND1
Synonyms:C6orf96
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000155906.16

Human Gene Nomenclature Database

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HGNCi
HGNC:21176 RMND1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614917 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NWS8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Combined oxidative phosphorylation deficiency 11 (COXPD11)4 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA severe, multisystemic, autosomal recessive, disorder characterized by deficiencies of multiple mitochondrial respiratory enzymes leading to neonatal hypotonia and lactic acidosis. Affected individuals may have respiratory insufficiency, foot deformities, or seizures.
See also OMIM:614922
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_069036417R → Q in COXPD11; alters homooligomeric formation of the protein; decreases the levels of mitochondrial protein synthesis. 3 PublicationsCorresponds to variant dbSNP:rs397515421EnsemblClinVar.1

Keywords - Diseasei

Disease mutation, Primary mitochondrial disease

Organism-specific databases

DisGeNET

More...
DisGeNETi
55005

MalaCards human disease database

More...
MalaCardsi
RMND1
MIMi614922 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000155906

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
324535 Combined oxidative phosphorylation defect type 11

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162401372

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

More...
DMDMi
91208248

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 12MitochondrionSequence analysisAdd BLAST12
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000022973213 – 449Required for meiotic nuclear division protein 1 homologAdd BLAST437

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9NWS8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NWS8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NWS8

PeptideAtlas

More...
PeptideAtlasi
Q9NWS8

PRoteomics IDEntifications database

More...
PRIDEi
Q9NWS8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
82973
82974 [Q9NWS8-2]
82975 [Q9NWS8-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NWS8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NWS8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000155906 Expressed in 214 organ(s), highest expression level in adult mammalian kidney

CleanEx database of gene expression profiles

More...
CleanExi
HS_RMND1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NWS8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NWS8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA031397
HPA031398
HPA031399

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homooligomer (PubMed:23022098, PubMed:25604853).2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
FAM9BQ8IZU03EBI-4401316,EBI-10175124

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
120337, 43 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NWS8, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356272

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9NWS8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NWS8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RMD1/sif2 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2861 Eukaryota
COG1723 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013337

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG093175

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9NWS8

Identification of Orthologs from Complete Genome Data

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OMAi
DLMQCTA

Database of Orthologous Groups

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OrthoDBi
EOG091G09ZY

Database for complete collections of gene phylogenies

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PhylomeDBi
Q9NWS8

TreeFam database of animal gene trees

More...
TreeFami
TF105813

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR003734 DUF155

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02582 DUF155, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NWS8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPATLLRAVA RSHHILSKAH QCRRIGHLML KPLKEFENTT CSTLTIRQSL
60 70 80 90 100
DLFLPDKTAS GLNKSQILEM NQKKSDTSML SPLNAARCQD EKAHLPTMKS
110 120 130 140 150
FGTHRRVTHK PNLLGSKWFI KILKRHFSSV STETFVPKQD FPQVKRPLKA
160 170 180 190 200
SRTRQPSRTN LPVLSVNEDL MHCTAFATAD EYHLGNLSQD LASHGYVEVT
210 220 230 240 250
SLPRDAANIL VMGVENSAKE GDPGTIFFFR EGAAVFWNVK DKTMKHVMKV
260 270 280 290 300
LEKHEIQPYE IALVHWENEE LNYIKIEGQS KLHRGEIKLN SELDLDDAIL
310 320 330 340 350
EKFAFSNALC LSVKLAIWEA SLDKFIESIQ SIPEALKAGK KVKLSHEEVM
360 370 380 390 400
QKIGELFALR HRINLSSDFL ITPDFYWDRE NLEGLYDKTC QFLSIGRRVK
410 420 430 440
VMNEKLQHCM ELTDLMRNHL NEKRALRLEW MIVILITIEV MFELGRVFF
Length:449
Mass (Da):51,604
Last modified:April 4, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC4A7B8F6A397B385
GO
Isoform 2 (identifier: Q9NWS8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-211: Missing.

Note: No experimental confirmation available.
Show »
Length:238
Mass (Da):27,846
Checksum:iEC4E8714002497DC
GO
Isoform 3 (identifier: Q9NWS8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     205-208: DAAN → GTSS
     209-449: Missing.

Note: No experimental confirmation available.
Show »
Length:208
Mass (Da):23,411
Checksum:i8A6E6A5F589C8065
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WXU0A0A087WXU0_HUMAN
Required for meiotic nuclear divisi...
RMND1
279Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5SZ82Q5SZ82_HUMAN
Required for meiotic nuclear divisi...
RMND1
211Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Y4P5A0A2R8Y4P5_HUMAN
Required for meiotic nuclear divisi...
RMND1
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Y4J4A0A2R8Y4J4_HUMAN
Required for meiotic nuclear divisi...
RMND1
444Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8YFC3A0A2R8YFC3_HUMAN
Required for meiotic nuclear divisi...
RMND1
213Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2U3TZJ1A0A2U3TZJ1_HUMAN
Required for meiotic nuclear divisi...
RMND1
38Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti170L → P in BAA91299 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05186442S → I. Corresponds to variant dbSNP:rs11550103EnsemblClinVar.1
Natural variantiVAR_05186547R → H. Corresponds to variant dbSNP:rs6934360EnsemblClinVar.1
Natural variantiVAR_025754132T → M2 PublicationsCorresponds to variant dbSNP:rs3734800EnsemblClinVar.1
Natural variantiVAR_069036417R → Q in COXPD11; alters homooligomeric formation of the protein; decreases the levels of mitochondrial protein synthesis. 3 PublicationsCorresponds to variant dbSNP:rs397515421EnsemblClinVar.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0177351 – 211Missing in isoform 2. CuratedAdd BLAST211
Alternative sequenceiVSP_017738205 – 208DAAN → GTSS in isoform 3. 1 Publication4
Alternative sequenceiVSP_017739209 – 449Missing in isoform 3. 1 PublicationAdd BLAST241

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK000634 mRNA Translation: BAA91299.1
AK292339 mRNA Translation: BAF85028.1
AL590413 Genomic DNA No translation available.
AL590543 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47747.1
BC012081 mRNA Translation: AAH12081.1
BC106065 mRNA Translation: AAI06066.1
BC119683 mRNA Translation: AAI19684.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5232.1 [Q9NWS8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001258866.1, NM_001271937.1
NP_060379.2, NM_017909.3 [Q9NWS8-1]
XP_005267097.1, XM_005267040.3 [Q9NWS8-2]
XP_016866477.1, XM_017010988.1 [Q9NWS8-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.486835
Hs.744622

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367303; ENSP00000356272; ENSG00000155906 [Q9NWS8-1]
ENST00000444024; ENSP00000412708; ENSG00000155906 [Q9NWS8-1]
ENST00000491268; ENSP00000494948; ENSG00000155906 [Q9NWS8-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
55005

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55005

UCSC genome browser

More...
UCSCi
uc003qoi.4 human [Q9NWS8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000634 mRNA Translation: BAA91299.1
AK292339 mRNA Translation: BAF85028.1
AL590413 Genomic DNA No translation available.
AL590543 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47747.1
BC012081 mRNA Translation: AAH12081.1
BC106065 mRNA Translation: AAI06066.1
BC119683 mRNA Translation: AAI19684.1
CCDSiCCDS5232.1 [Q9NWS8-1]
RefSeqiNP_001258866.1, NM_001271937.1
NP_060379.2, NM_017909.3 [Q9NWS8-1]
XP_005267097.1, XM_005267040.3 [Q9NWS8-2]
XP_016866477.1, XM_017010988.1 [Q9NWS8-2]
UniGeneiHs.486835
Hs.744622

3D structure databases

ProteinModelPortaliQ9NWS8
SMRiQ9NWS8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120337, 43 interactors
IntActiQ9NWS8, 4 interactors
STRINGi9606.ENSP00000356272

PTM databases

iPTMnetiQ9NWS8
PhosphoSitePlusiQ9NWS8

Polymorphism and mutation databases

DMDMi91208248

Proteomic databases

EPDiQ9NWS8
MaxQBiQ9NWS8
PaxDbiQ9NWS8
PeptideAtlasiQ9NWS8
PRIDEiQ9NWS8
ProteomicsDBi82973
82974 [Q9NWS8-2]
82975 [Q9NWS8-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367303; ENSP00000356272; ENSG00000155906 [Q9NWS8-1]
ENST00000444024; ENSP00000412708; ENSG00000155906 [Q9NWS8-1]
ENST00000491268; ENSP00000494948; ENSG00000155906 [Q9NWS8-3]
GeneIDi55005
KEGGihsa:55005
UCSCiuc003qoi.4 human [Q9NWS8-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
55005
DisGeNETi55005
EuPathDBiHostDB:ENSG00000155906.16

GeneCards: human genes, protein and diseases

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GeneCardsi
RMND1
HGNCiHGNC:21176 RMND1
HPAiHPA031397
HPA031398
HPA031399
MalaCardsiRMND1
MIMi614917 gene
614922 phenotype
neXtProtiNX_Q9NWS8
OpenTargetsiENSG00000155906
Orphaneti324535 Combined oxidative phosphorylation defect type 11
PharmGKBiPA162401372

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG2861 Eukaryota
COG1723 LUCA
GeneTreeiENSGT00390000013337
HOVERGENiHBG093175
InParanoidiQ9NWS8
OMAiDLMQCTA
OrthoDBiEOG091G09ZY
PhylomeDBiQ9NWS8
TreeFamiTF105813

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55005

Protein Ontology

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PROi
PR:Q9NWS8

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000155906 Expressed in 214 organ(s), highest expression level in adult mammalian kidney
CleanExiHS_RMND1
ExpressionAtlasiQ9NWS8 baseline and differential
GenevisibleiQ9NWS8 HS

Family and domain databases

InterProiView protein in InterPro
IPR003734 DUF155
PfamiView protein in Pfam
PF02582 DUF155, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRMND1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NWS8
Secondary accession number(s): A8K8H4
, Q0VDG6, Q5SZ48, Q5SZ83, Q6NSC5, Q96EN7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: October 10, 2018
This is version 120 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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