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Entry version 140 (07 Apr 2021)
Sequence version 1 (01 Oct 2000)
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Protein

Transmembrane protein 248

Gene

TMEM248

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NWD8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 248
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM248
Synonyms:C7orf42
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25476, TMEM248

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NWD8

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000106609.16

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei21 – 41HelicalSequence analysisAdd BLAST21
Transmembranei179 – 199HelicalSequence analysisAdd BLAST21
Transmembranei236 – 258HelicalSequence analysisAdd BLAST23
Transmembranei270 – 290HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55069

Open Targets

More...
OpenTargetsi
ENSG00000106609

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147358581

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NWD8, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM248

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74734652

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002951261 – 314Transmembrane protein 248Add BLAST314

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NWD8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NWD8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NWD8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NWD8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NWD8

PeptideAtlas

More...
PeptideAtlasi
Q9NWD8

PRoteomics IDEntifications database

More...
PRIDEi
Q9NWD8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
82927 [Q9NWD8-1]
82928 [Q9NWD8-2]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q9NWD8, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NWD8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NWD8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000106609, Expressed in prostate gland and 236 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NWD8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NWD8, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000106609, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120386, 47 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NWD8, 45 interactors

Molecular INTeraction database

More...
MINTi
Q9NWD8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000340668

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NWD8, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM248 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R6D8, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153883

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_080742_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NWD8

Identification of Orthologs from Complete Genome Data

More...
OMAi
HSHCEQV

Database of Orthologous Groups

More...
OrthoDBi
1623112at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NWD8

TreeFam database of animal gene trees

More...
TreeFami
TF331542

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039493, TMEM248/TMEM219
IPR039587, TMEM248/TMEM219_dom

The PANTHER Classification System

More...
PANTHERi
PTHR16002, PTHR16002, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14940, TMEM219, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NWD8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFSINPLENL KVYISSRPPL VVFMISVSAM AIAFLTLGYF FKIKEIKSPE
60 70 80 90 100
MAEDWNTFLL RFNDLDLCVS ENETLKHLTN DTTTPESTMT SGQARASTQS
110 120 130 140 150
PQALEDSGPV NISVSITLTL DPLKPFGGYS RNVTHLYSTI LGHQIGLSGR
160 170 180 190 200
EAHEEINITF TLPTAWSSDD CALHGHCEQV VFTACMTLTA SPGVFPVTVQ
210 220 230 240 250
PPHCVPDTYS NATLWYKIFT TARDANTKYA QDYNPFWCYK GAIGKVYHAL
260 270 280 290 300
NPKLTVIVPD DDRSLINLHL MHTSYFLFVM VITMFCYAVI KGRPSKLRQS
310
NPEFCPEKVA LAEA
Length:314
Mass (Da):35,052
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB701BDC9B269C1BB
GO
Isoform 2 (identifier: Q9NWD8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     200-203: QPPH → MTVH
     204-314: Missing.

Show »
Length:203
Mass (Da):22,318
Checksum:iA69DC524847D1579
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WE75F8WE75_HUMAN
Transmembrane protein 248
TMEM248
139Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U3KQ21U3KQ21_HUMAN
Transmembrane protein 248
TMEM248
114Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J3C8C9J3C8_HUMAN
Transmembrane protein 248
TMEM248
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JKP5C9JKP5_HUMAN
Transmembrane protein 248
TMEM248
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti195F → L in BAD96494 (Ref. 2) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_026736200 – 203QPPH → MTVH in isoform 2. 1 Publication4
Alternative sequenceiVSP_026737204 – 314Missing in isoform 2. 1 PublicationAdd BLAST111

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK000961 mRNA Translation: BAA91444.1
AK222774 mRNA Translation: BAD96494.1
CH236961 Genomic DNA Translation: EAL23731.1
BC008675 mRNA Translation: AAH08675.1
BC010519 mRNA Translation: AAH10519.1
BC012562 mRNA Translation: AAH12562.1
BC041764 mRNA Translation: AAH41764.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5536.1 [Q9NWD8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_060464.1, NM_017994.4 [Q9NWD8-1]
XP_005250539.1, XM_005250482.3 [Q9NWD8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000341567; ENSP00000340668; ENSG00000106609 [Q9NWD8-1]
ENST00000433271; ENSP00000405558; ENSG00000106609 [Q9NWD8-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55069

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55069

UCSC genome browser

More...
UCSCi
uc003tvk.4, human [Q9NWD8-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000961 mRNA Translation: BAA91444.1
AK222774 mRNA Translation: BAD96494.1
CH236961 Genomic DNA Translation: EAL23731.1
BC008675 mRNA Translation: AAH08675.1
BC010519 mRNA Translation: AAH10519.1
BC012562 mRNA Translation: AAH12562.1
BC041764 mRNA Translation: AAH41764.1
CCDSiCCDS5536.1 [Q9NWD8-1]
RefSeqiNP_060464.1, NM_017994.4 [Q9NWD8-1]
XP_005250539.1, XM_005250482.3 [Q9NWD8-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120386, 47 interactors
IntActiQ9NWD8, 45 interactors
MINTiQ9NWD8
STRINGi9606.ENSP00000340668

PTM databases

GlyGeniQ9NWD8, 2 sites
iPTMnetiQ9NWD8
PhosphoSitePlusiQ9NWD8

Genetic variation databases

BioMutaiTMEM248
DMDMi74734652

Proteomic databases

EPDiQ9NWD8
jPOSTiQ9NWD8
MassIVEiQ9NWD8
MaxQBiQ9NWD8
PaxDbiQ9NWD8
PeptideAtlasiQ9NWD8
PRIDEiQ9NWD8
ProteomicsDBi82927 [Q9NWD8-1]
82928 [Q9NWD8-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
3083, 65 antibodies

The DNASU plasmid repository

More...
DNASUi
55069

Genome annotation databases

EnsembliENST00000341567; ENSP00000340668; ENSG00000106609 [Q9NWD8-1]
ENST00000433271; ENSP00000405558; ENSG00000106609 [Q9NWD8-2]
GeneIDi55069
KEGGihsa:55069
UCSCiuc003tvk.4, human [Q9NWD8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55069
DisGeNETi55069

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM248
HGNCiHGNC:25476, TMEM248
HPAiENSG00000106609, Low tissue specificity
neXtProtiNX_Q9NWD8
OpenTargetsiENSG00000106609
PharmGKBiPA147358581
VEuPathDBiHostDB:ENSG00000106609.16

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502R6D8, Eukaryota
GeneTreeiENSGT00940000153883
HOGENOMiCLU_080742_0_0_1
InParanoidiQ9NWD8
OMAiHSHCEQV
OrthoDBi1623112at2759
PhylomeDBiQ9NWD8
TreeFamiTF331542

Enzyme and pathway databases

PathwayCommonsiQ9NWD8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
55069, 10 hits in 999 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TMEM248, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55069
PharosiQ9NWD8, Tdark

Protein Ontology

More...
PROi
PR:Q9NWD8
RNActiQ9NWD8, protein

Gene expression databases

BgeeiENSG00000106609, Expressed in prostate gland and 236 other tissues
ExpressionAtlasiQ9NWD8, baseline and differential
GenevisibleiQ9NWD8, HS

Family and domain databases

InterProiView protein in InterPro
IPR039493, TMEM248/TMEM219
IPR039587, TMEM248/TMEM219_dom
PANTHERiPTHR16002, PTHR16002, 1 hit
PfamiView protein in Pfam
PF14940, TMEM219, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM248_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NWD8
Secondary accession number(s): Q53H07, Q96FR2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: October 1, 2000
Last modified: April 7, 2021
This is version 140 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families
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