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Entry version 122 (08 May 2019)
Sequence version 3 (18 May 2010)
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Protein

Distal membrane-arm assembly complex protein 2

Gene

DMAC2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Distal membrane-arm assembly complex protein 2Curated
Alternative name(s):
ATP synthase subunit s-like proteinCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DMAC2Imported
Synonyms:ATP5SLImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:25496 DMAC2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NW81

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55101

Open Targets

More...
OpenTargetsi
ENSG00000105341

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162377263

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DMAC2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296439436

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003186951 – 257Distal membrane-arm assembly complex protein 2Add BLAST257

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei253PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9NW81

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9NW81

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NW81

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NW81

PeptideAtlas

More...
PeptideAtlasi
Q9NW81

PRoteomics IDEntifications database

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PRIDEi
Q9NW81

ProteomicsDB human proteome resource

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ProteomicsDBi
82910
82911 [Q9NW81-2]
82912 [Q9NW81-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NW81

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q9NW81

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000105341 Expressed in 222 organ(s), highest expression level in apex of heart

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9NW81 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NW81 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA041427

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with incompletely assembled mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
120411, 5 interactors

Protein interaction database and analysis system

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IntActi
Q9NW81, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000403910

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9NW81

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ATP synthase subunit s family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IS4E Eukaryota
ENOG4111PMF LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160500

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000034116

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NW81

Identification of Orthologs from Complete Genome Data

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OMAi
HFYDVEA

Database of Orthologous Groups

More...
OrthoDBi
1458966at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NW81

TreeFam database of animal gene trees

More...
TreeFami
TF315274

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026063 ATP5S/ATP5SL
IPR032675 LRR_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13382:SF10 PTHR13382:SF10, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (6+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 6 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 6 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NW81-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAPWASLRL VAPMWNGRIR GIHRLGAAVA PEGNQKKKRT ILQFLTNYFY
60 70 80 90 100
DVEALRDYLL QREMYKVHEK NRSYTWLEKQ HGPYGAGAFF ILKQGGAVKF
110 120 130 140 150
RDKEWIRPDK YGHFSQEFWN FCEVPVEAVD AGDCDINYEG LDNLLRLKEL
160 170 180 190 200
QSLSLQRCCH VDDWCLSRLY PLADSLQELS LAGCPRISER GLACLHHLQN
210 220 230 240 250
LRRLDISDLP AVSNPGLTQI LVEEMLPNCE VVGVDWAEGL KSGPEEQPRD

TASPVPA
Length:257
Mass (Da):29,267
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i29CBFD02143DE806
GO
Isoform 2 (identifier: Q9NW81-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     73-99: Missing.
     145-257: LRLKELQSLS...PRDTASPVPA → RTSAGWTSRT...RLWESTGLRA

Note: No experimental confirmation available.
Show »
Length:158
Mass (Da):18,602
Checksum:i8387C635C5F26D39
GO
Isoform 3 (identifier: Q9NW81-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-6: MAAPWA → MWDLVLEDRRMN
     145-257: LRLKELQSLS...PRDTASPVPA → RTSAGWTSRT...RLWESTGLRA

Show »
Length:191
Mass (Da):22,471
Checksum:i7F1EEBB93765A5EE
GO
Isoform 4 (identifier: Q9NW81-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-6: MAAPWA → MWDLVLEDRRMN

Note: No experimental confirmation available.
Show »
Length:263
Mass (Da):30,200
Checksum:iB8A3EFDDE672C998
GO
Isoform 5 (identifier: Q9NW81-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     73-99: Missing.

Note: No experimental confirmation available.
Show »
Length:230
Mass (Da):26,331
Checksum:i430D9722498CE8E3
GO
Isoform 6 (identifier: Q9NW81-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     145-257: LRLKELQSLS...PRDTASPVPA → RTSAGWTSRT...RLWESTGLRA

Note: No experimental confirmation available.
Show »
Length:185
Mass (Da):21,539
Checksum:i310CA9F8CAB2E26E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4DFT4B4DFT4_HUMAN
Distal membrane-arm assembly comple...
DMAC2
178Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QZC4M0QZC4_HUMAN
Distal membrane-arm assembly comple...
DMAC2
172Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QZP7M0QZP7_HUMAN
Distal membrane-arm assembly comple...
DMAC2
150Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ESN5K7ESN5_HUMAN
Distal membrane-arm assembly comple...
DMAC2
101Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EIV4K7EIV4_HUMAN
Distal membrane-arm assembly comple...
DMAC2
176Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R078M0R078_HUMAN
Distal membrane-arm assembly comple...
DMAC2
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QX81M0QX81_HUMAN
Distal membrane-arm assembly comple...
DMAC2
22Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti128A → S in BAG60467 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0577989R → C. Corresponds to variant dbSNP:rs2231938Ensembl.1
Natural variantiVAR_05779923H → R1 PublicationCorresponds to variant dbSNP:rs2231939Ensembl.1
Natural variantiVAR_05780034N → S1 PublicationCorresponds to variant dbSNP:rs2231940Ensembl.1
Natural variantiVAR_060165159C → S1 PublicationCorresponds to variant dbSNP:rs1043413Ensembl.1
Natural variantiVAR_057801230E → K. Corresponds to variant dbSNP:rs2231943Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0438071 – 6MAAPWA → MWDLVLEDRRMN in isoform 3 and isoform 4. 1 Publication6
Alternative sequenceiVSP_03127073 – 99Missing in isoform 2 and isoform 5. 2 PublicationsAdd BLAST27
Alternative sequenceiVSP_031271145 – 257LRLKE…SPVPA → RTSAGWTSRTSLPCPTLASL RYWWRRCCPIARLWESTGLR A in isoform 2, isoform 3 and isoform 6. 2 PublicationsAdd BLAST113

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK001103 mRNA Translation: BAA91503.1
AK293132 mRNA Translation: BAG56681.1
AK297698 mRNA Translation: BAG60056.1
AK298197 mRNA Translation: BAG60467.1
AK301940 mRNA Translation: BAG63360.1
AC011526 Genomic DNA No translation available.
AC005795 Genomic DNA No translation available.
AC005945 Genomic DNA No translation available.
CH471126 Genomic DNA Translation: EAW57042.1
CH471126 Genomic DNA Translation: EAW57043.1
BC013323 mRNA Translation: AAH13323.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33032.1 [Q9NW81-1]
CCDS54269.1 [Q9NW81-3]
CCDS54270.1 [Q9NW81-4]
CCDS54271.1 [Q9NW81-5]
CCDS59389.1 [Q9NW81-2]
CCDS59390.1 [Q9NW81-6]

NCBI Reference Sequences

More...
RefSeqi
NP_001161339.1, NM_001167867.1 [Q9NW81-4]
NP_001161340.1, NM_001167868.1 [Q9NW81-3]
NP_001161341.1, NM_001167869.1 [Q9NW81-6]
NP_001161342.1, NM_001167870.1 [Q9NW81-2]
NP_001161343.1, NM_001167871.1 [Q9NW81-5]
NP_001307767.1, NM_001320838.1
NP_001307769.1, NM_001320840.1
NP_001307770.1, NM_001320841.1
NP_060505.2, NM_018035.2 [Q9NW81-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000221943; ENSP00000221943; ENSG00000105341 [Q9NW81-1]
ENST00000301183; ENSP00000301183; ENSG00000105341 [Q9NW81-3]
ENST00000417807; ENSP00000403910; ENSG00000105341 [Q9NW81-4]
ENST00000438807; ENSP00000397413; ENSG00000105341 [Q9NW81-2]
ENST00000589970; ENSP00000466485; ENSG00000105341 [Q9NW81-6]
ENST00000592922; ENSP00000467205; ENSG00000105341 [Q9NW81-5]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55101

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55101

UCSC genome browser

More...
UCSCi
uc002oqv.4 human [Q9NW81-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001103 mRNA Translation: BAA91503.1
AK293132 mRNA Translation: BAG56681.1
AK297698 mRNA Translation: BAG60056.1
AK298197 mRNA Translation: BAG60467.1
AK301940 mRNA Translation: BAG63360.1
AC011526 Genomic DNA No translation available.
AC005795 Genomic DNA No translation available.
AC005945 Genomic DNA No translation available.
CH471126 Genomic DNA Translation: EAW57042.1
CH471126 Genomic DNA Translation: EAW57043.1
BC013323 mRNA Translation: AAH13323.1
CCDSiCCDS33032.1 [Q9NW81-1]
CCDS54269.1 [Q9NW81-3]
CCDS54270.1 [Q9NW81-4]
CCDS54271.1 [Q9NW81-5]
CCDS59389.1 [Q9NW81-2]
CCDS59390.1 [Q9NW81-6]
RefSeqiNP_001161339.1, NM_001167867.1 [Q9NW81-4]
NP_001161340.1, NM_001167868.1 [Q9NW81-3]
NP_001161341.1, NM_001167869.1 [Q9NW81-6]
NP_001161342.1, NM_001167870.1 [Q9NW81-2]
NP_001161343.1, NM_001167871.1 [Q9NW81-5]
NP_001307767.1, NM_001320838.1
NP_001307769.1, NM_001320840.1
NP_001307770.1, NM_001320841.1
NP_060505.2, NM_018035.2 [Q9NW81-1]

3D structure databases

SMRiQ9NW81
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120411, 5 interactors
IntActiQ9NW81, 1 interactor
STRINGi9606.ENSP00000403910

PTM databases

iPTMnetiQ9NW81
PhosphoSitePlusiQ9NW81

Polymorphism and mutation databases

BioMutaiDMAC2
DMDMi296439436

Proteomic databases

EPDiQ9NW81
jPOSTiQ9NW81
MaxQBiQ9NW81
PaxDbiQ9NW81
PeptideAtlasiQ9NW81
PRIDEiQ9NW81
ProteomicsDBi82910
82911 [Q9NW81-2]
82912 [Q9NW81-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55101
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000221943; ENSP00000221943; ENSG00000105341 [Q9NW81-1]
ENST00000301183; ENSP00000301183; ENSG00000105341 [Q9NW81-3]
ENST00000417807; ENSP00000403910; ENSG00000105341 [Q9NW81-4]
ENST00000438807; ENSP00000397413; ENSG00000105341 [Q9NW81-2]
ENST00000589970; ENSP00000466485; ENSG00000105341 [Q9NW81-6]
ENST00000592922; ENSP00000467205; ENSG00000105341 [Q9NW81-5]
GeneIDi55101
KEGGihsa:55101
UCSCiuc002oqv.4 human [Q9NW81-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55101
DisGeNETi55101

GeneCards: human genes, protein and diseases

More...
GeneCardsi
DMAC2
HGNCiHGNC:25496 DMAC2
HPAiHPA041427
neXtProtiNX_Q9NW81
OpenTargetsiENSG00000105341
PharmGKBiPA162377263

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IS4E Eukaryota
ENOG4111PMF LUCA
GeneTreeiENSGT00940000160500
HOGENOMiHOG000034116
InParanoidiQ9NW81
OMAiHFYDVEA
OrthoDBi1458966at2759
PhylomeDBiQ9NW81
TreeFamiTF315274

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ATP5SL

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55101

Protein Ontology

More...
PROi
PR:Q9NW81

Gene expression databases

BgeeiENSG00000105341 Expressed in 222 organ(s), highest expression level in apex of heart
ExpressionAtlasiQ9NW81 baseline and differential
GenevisibleiQ9NW81 HS

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR026063 ATP5S/ATP5SL
IPR032675 LRR_dom_sf
PANTHERiPTHR13382:SF10 PTHR13382:SF10, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDMAC2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NW81
Secondary accession number(s): B4DDC0
, B4DMZ4, B4DP55, B4DXE8, F5H4W7, K7EMF6, Q96D43
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: May 18, 2010
Last modified: May 8, 2019
This is version 122 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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