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UniProtKB - Q9NW07 (ZN358_HUMAN)

Entry version 162 (10 Feb 2021)
Sequence version 2 (07 Jul 2009)
Previous versions | rss
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Protein

Zinc finger protein 358

Gene

ZNF358

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri151 – 173C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri179 – 201C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri207 – 229C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri235 – 257C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri263 – 285C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri291 – 313C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri319 – 341C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri347 – 369C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri375 – 397C2H2-type 9PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9NW07

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 358
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF358
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16838, ZNF358

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NW07

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000198816.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		140467

Open Targets

More...OpenTargetsi		ENSG00000198816

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38189

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9NW07, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF358

Domain mapping of disease mutations (DMDM)

More...DMDMi		251757418

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000475471 – 568Zinc finger protein 358Add BLAST568

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9NW07

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9NW07

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9NW07

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9NW07

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NW07

PeptideAtlas

More...PeptideAtlasi		Q9NW07

PRoteomics IDEntifications database

More...PRIDEi		Q9NW07

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		82884

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NW07

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NW07

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000198816, Expressed in apex of heart and 209 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9NW07, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NW07, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000198816, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		126619, 7 interactors

Protein interaction database and analysis system

More...IntActi		Q9NW07, 4 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000472305

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9NW07, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9NW07

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi400 – 416Poly-AlaAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri151 – 173C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri179 – 201C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri207 – 229C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri235 – 257C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri263 – 285C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri291 – 313C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri319 – 341C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri347 – 369C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri375 – 397C2H2-type 9PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000162948

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_025444_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NW07

Identification of Orthologs from Complete Genome Data

More...OMAi		WVKEEGA

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NW07

TreeFam database of animal gene trees

More...TreeFami		TF350840

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 7 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 9 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 5 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 9 hits
PS50157, ZINC_FINGER_C2H2_2, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9NW07-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRSVLVRNP GHKGLRPVYE ELDSDSEDLD PNPEDLDPVS EDPEPDPEDL 
        60         70         80         90        100
NTVPEDVDPS YEDLEPVSED LDPDAEAPGS EPQDPDPMSS SFDLDPDVIG 
       110        120        130        140        150
PVPLILDPNS DTLSPGDPKV DPISSGLTAT PQVLATSPAV LPAPASPPRP 
       160        170        180        190        200
FSCPDCGRAF RRSSGLSQHR RTHSGEKPYR CPDCGKSFSH GATLAQHRGI 
       210        220        230        240        250
HTGARPYQCA ACGKAFGWRS TLLKHRSSHS GEKPHHCPVC GKAFGHGSLL 
       260        270        280        290        300
AQHLRTHGGP RPHKCPVCAK GFGQGSALLK HLRTHTGERP YPCPQCGKAF 
       310        320        330        340        350
GQSSALLQHQ RTHTAERPYR CPHCGKAFGQ SSNLQHHLRI HTGERPYACP 
       360        370        380        390        400
HCSKAFGQSS ALLQHLHVHS GERPYRCQLC GKAFGQASSL TKHKRVHEGA 
       410        420        430        440        450
AAAAAAAAAA AAAAAAGLGL GPGLSPASMM RPGQVSLLGP DAVSVLGSGL 
       460        470        480        490        500
GLSPGTSSGR NPDPGSGPGT LPDPSSKPLP GSRSTPSPTP VESSDPKAGH 
       510        520        530        540        550
DAGPDLVPSP DLDPVPSPDP DPVPSPDPNP VSCPDPCSPT RGTVSPALPT 
       560 
GESPEWVQEQ GALLGPDG
Length:568
Mass (Da):59,287
Last modified:July 7, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i347131478D2A5FF8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R2S5M0R2S5_HUMAN
Zinc finger protein 358
ZNF358
169Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH14002 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAA91582 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti242K → Q in CX782162 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06194432N → S. Corresponds to variant dbSNP:rs11555037Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC008878 Genomic DNA No translation available.
BC003585 mRNA Translation: AAH03585.1
BC014002 mRNA Translation: AAH14002.1 Different initiation.
CX782162 mRNA No translation available.
AK001252 mRNA Translation: BAA91582.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32890.2

NCBI Reference Sequences

More...RefSeqi		NP_060553.4, NM_018083.4
XP_005272517.1, XM_005272460.3
XP_011525997.1, XM_011527695.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000597229; ENSP00000472305; ENSG00000198816

Database of genes from NCBI RefSeq genomes

More...GeneIDi		140467

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:140467

UCSC genome browser

More...UCSCi		uc002mgn.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008878 Genomic DNA No translation available.
BC003585 mRNA Translation: AAH03585.1
BC014002 mRNA Translation: AAH14002.1 Different initiation.
CX782162 mRNA No translation available.
AK001252 mRNA Translation: BAA91582.1 Different initiation.
CCDSiCCDS32890.2
RefSeqiNP_060553.4, NM_018083.4
XP_005272517.1, XM_005272460.3
XP_011525997.1, XM_011527695.1

3D structure databases

SMRiQ9NW07
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi126619, 7 interactors
IntActiQ9NW07, 4 interactors
STRINGi9606.ENSP00000472305

PTM databases

iPTMnetiQ9NW07
PhosphoSitePlusiQ9NW07

Genetic variation databases

BioMutaiZNF358
DMDMi251757418

Proteomic databases

EPDiQ9NW07
jPOSTiQ9NW07
MassIVEiQ9NW07
MaxQBiQ9NW07
PaxDbiQ9NW07
PeptideAtlasiQ9NW07
PRIDEiQ9NW07
ProteomicsDBi82884

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		12050, 120 antibodies

Genome annotation databases

EnsembliENST00000597229; ENSP00000472305; ENSG00000198816
GeneIDi140467
KEGGihsa:140467
UCSCiuc002mgn.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		140467
DisGeNETi140467

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF358
HGNCiHGNC:16838, ZNF358
HPAiENSG00000198816, Low tissue specificity
neXtProtiNX_Q9NW07
OpenTargetsiENSG00000198816
PharmGKBiPA38189
VEuPathDBiHostDB:ENSG00000198816.5

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000162948
HOGENOMiCLU_025444_0_0_1
InParanoidiQ9NW07
OMAiWVKEEGA
OrthoDBi1318335at2759
PhylomeDBiQ9NW07
TreeFamiTF350840

Enzyme and pathway databases

PathwayCommonsiQ9NW07

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		140467, 6 hits in 900 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF358, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		140467
PharosiQ9NW07, Tdark

Protein Ontology

More...PROi		PR:Q9NW07
RNActiQ9NW07, protein

Gene expression databases

BgeeiENSG00000198816, Expressed in apex of heart and 209 other tissues
ExpressionAtlasiQ9NW07, baseline and differential
GenevisibleiQ9NW07, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 7 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 9 hits
SUPFAMiSSF57667, SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 9 hits
PS50157, ZINC_FINGER_C2H2_2, 9 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN358_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NW07
Secondary accession number(s): Q9BTM7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: July 7, 2009
Last modified: February 10, 2021
This is version 162 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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