AIG1

Protein namesⁱ	Recommended name: Androgen-induced gene 1 protein Short name: AIG-1
Gene namesⁱ	Name:AIG1 ORF Names:CGI-103
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 6

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000146416.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:21607 AIG1
MIMⁱ	608514 gene
neXtProtⁱ	NX_Q9NVV5

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	1 – 21	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	39 – 59	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	88 – 108	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	124 – 144	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	167 – 187	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	197 – 217	HelicalSequence analysisAdd BLAST	21

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	51390
Open Targets More...OpenTargetsⁱ	ENSG00000146416
PharmGKBⁱ	PA134991331

Polymorphism and mutation databases

DMDMⁱ	56748615

DMDMⁱ

56748615

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000190098	1 – 245	Androgen-induced gene 1 proteinAdd BLAST		245

Proteomic databases

EPDⁱ	Q9NVV5
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9NVV5
PaxDbⁱ	Q9NVV5
PeptideAtlas More...PeptideAtlasⁱ	Q9NVV5
PRIDEⁱ	Q9NVV5
ProteomicsDBⁱ	82866 82867 [Q9NVV5-2] 82868 [Q9NVV5-3] 82869 [Q9NVV5-4] 82870 [Q9NVV5-5]
TopDownProteomicsⁱ	Q9NVV5-4 [Q9NVV5-4]

PTM databases

iPTMnetⁱ	Q9NVV5
PhosphoSitePlusⁱ	Q9NVV5

Expressionⁱ

Tissue specificityⁱ

Highly expressed in heart, ovary, testis, liver, and kidney, at lower levels in spleen, prostate, brain, skeletal muscle, pancreas, small intestine and colon, and undetected in peripheral blood leukocytes, thymus, lung and placenta. AIG1 expression is higher in hair follicles from males than from females.1 Publication

Inductionⁱ

By dihydrotestosterone (DHT).1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000146416 Expressed in 208 organ(s), highest expression level in liver
CleanExⁱ	HS_AIG1
ExpressionAtlasⁱ	Q9NVV5 baseline and differential
Genevisibleⁱ	Q9NVV5 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA060766

HPAⁱ

HPA060766

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
MFF	Q9GZY8-5	4	EBI-11957045,EBI-11956541
RCHY1	Q96PM5	4	EBI-3942989,EBI-947779

Protein-protein interaction databases

BioGridⁱ	119519, 7 interactors
IntActⁱ	Q9NVV5, 42 interactors
STRINGⁱ	9606.ENSP00000350509

Chemistry databases

BindingDBⁱ

Q9NVV5

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9NVV5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the AIG1 family.Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG3989 Eukaryota ENOG4111HQA LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000012526
HOVERGENⁱ	HBG050468
InParanoidⁱ	Q9NVV5
OMAⁱ	HTNIVIF
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0LUO
PhylomeDBⁱ	Q9NVV5
TreeFamⁱ	TF318170

Family and domain databases

InterProⁱ	View protein in InterPro IPR006838 Far-17a_AIG1
PANTHERⁱ	PTHR10989 PTHR10989, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04750 Far-17a_AIG1, 1 hit

Sequences (6+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 6 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 6 described isoforms and 5 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9NVV5-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MALVPCQVLR MAILLSYCSI LCNYKAIEMP SHQTYGGSWK FLTFIDLVIQ 
        60         70         80         90        100
AVFFGICVLT DLSSLLTRGS GNQEQERQLK KLISLRDWML AVLAFPVGVF 
       110        120        130        140        150
VVAVFWIIYA YDREMIYPKL LDNFIPGWLN HGMHTTVLPF ILIEMRTSHH 
       160        170        180        190        200
QYPSRSSGLT AICTFSVGYI LWVCWVHHVT GMWVYPFLEH IGPGARIIFF 
       210        220        230        240 
GSTTILMNFL YLLGEVLNNY IWDTQKKPPS WQDMKIKFMY LGPSS

Length:245

Mass (Da):28,222

Last modified:December 21, 2004 - v2

Checksum:ⁱ06C0C8A6BDBF3694

GO

Isoform 2 (identifier: Q9NVV5-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
227-245: KPPSWQDMKIKFMYLGPSS → SMEEEKEKPKLE

« Hide

        10         20         30         40         50
MALVPCQVLR MAILLSYCSI LCNYKAIEMP SHQTYGGSWK FLTFIDLVIQ 
        60         70         80         90        100
AVFFGICVLT DLSSLLTRGS GNQEQERQLK KLISLRDWML AVLAFPVGVF 
       110        120        130        140        150
VVAVFWIIYA YDREMIYPKL LDNFIPGWLN HGMHTTVLPF ILIEMRTSHH 
       160        170        180        190        200
QYPSRSSGLT AICTFSVGYI LWVCWVHHVT GMWVYPFLEH IGPGARIIFF 
       210        220        230 
GSTTILMNFL YLLGEVLNNY IWDTQKSMEE EKEKPKLE

Show »

Length:238

Mass (Da):27,458

Checksum:ⁱDF5D5B8FC41A2C95

GO

Isoform 3 (identifier: Q9NVV5-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
48-99: Missing.
227-245: KPPSWQDMKIKFMYLGPSS → SMEEEKEKPKLE

« Hide

        10         20         30         40         50
MALVPCQVLR MAILLSYCSI LCNYKAIEMP SHQTYGGSWK FLTFIDLFVV 
        60         70         80         90        100
AVFWIIYAYD REMIYPKLLD NFIPGWLNHG MHTTVLPFIL IEMRTSHHQY 
       110        120        130        140        150
PSRSSGLTAI CTFSVGYILW VCWVHHVTGM WVYPFLEHIG PGARIIFFGS 
       160        170        180 
TTILMNFLYL LGEVLNNYIW DTQKSMEEEK EKPKLE

Show »

Length:186

Mass (Da):21,715

Checksum:ⁱ77322CC43C44F5C2

GO

Isoform 4 (identifier: Q9NVV5-4) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-10: Missing.
227-245: KPPSWQDMKIKFMYLGPSS → SMEEEKEKPKLE

« Hide

        10         20         30         40         50
MAILLSYCSI LCNYKAIEMP SHQTYGGSWK FLTFIDLVIQ AVFFGICVLT 
        60         70         80         90        100
DLSSLLTRGS GNQEQERQLK KLISLRDWML AVLAFPVGVF VVAVFWIIYA 
       110        120        130        140        150
YDREMIYPKL LDNFIPGWLN HGMHTTVLPF ILIEMRTSHH QYPSRSSGLT 
       160        170        180        190        200
AICTFSVGYI LWVCWVHHVT GMWVYPFLEH IGPGARIIFF GSTTILMNFL 
       210        220 
YLLGEVLNNY IWDTQKSMEE EKEKPKLE

Note: No experimental confirmation available.

Show »

Length:228

Mass (Da):26,347

Checksum:ⁱ761CD65BB7F9F159

GO

Isoform 5 (identifier: Q9NVV5-5) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
135-137: TTV → FKA
138-245: Missing.

« Hide

        10         20         30         40         50
MALVPCQVLR MAILLSYCSI LCNYKAIEMP SHQTYGGSWK FLTFIDLVIQ 
        60         70         80         90        100
AVFFGICVLT DLSSLLTRGS GNQEQERQLK KLISLRDWML AVLAFPVGVF 
       110        120        130 
VVAVFWIIYA YDREMIYPKL LDNFIPGWLN HGMHFKA

Note: No experimental confirmation available.

Show »

Length:137

Mass (Da):15,713

Checksum:ⁱ7EEF2A92A3787CA3

GO

Isoform 6 (identifier: Q9NVV5-6) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
134-245: HTTVLPFILI...IKFMYLGPSS → L

« Hide

        10         20         30         40         50
MALVPCQVLR MAILLSYCSI LCNYKAIEMP SHQTYGGSWK FLTFIDLVIQ 
        60         70         80         90        100
AVFFGICVLT DLSSLLTRGS GNQEQERQLK KLISLRDWML AVLAFPVGVF 
       110        120        130 
VVAVFWIIYA YDREMIYPKL LDNFIPGWLN HGML

Note: No experimental confirmation available.

Show »

Length:134

Mass (Da):15,342

Checksum:ⁱ6463787CA31E154B

GO

Computationally mapped potential isoform sequencesⁱ

There are 5 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q5THU2	Q5THU2_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	47	Annotation score:
Q5T2H0	Q5T2H0_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	138	Annotation score:
Q5T2H4	Q5T2H4_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	192	Annotation score:
Q5T2H3	Q5T2H3_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	123	Annotation score:
A0A2R8YCJ8	A0A2R8YCJ8_HUMAN	Androgen-induced gene 1 protein Androgen-induced gene 1 protein	AIG1	231	Annotation score:

Sequence cautionⁱ

The sequence AAD34098 differs from that shown. Reason: Frameshift at positions 182, 193 and 223.Curated

The sequence CAE45823 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	70	S → I in AAD41087 (PubMed:11266118).Curated		1
Sequence conflictⁱ	191	I → F in BAA91640 (PubMed:14702039).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_057502	151	Q → E. Corresponds to variant dbSNP:rs1053193Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_012314	1 – 10	Missing in isoform 4. 1 Publication	10
Alternative sequenceⁱVSP_012315	48 – 99	Missing in isoform 3. 1 PublicationAdd BLAST	52
Alternative sequenceⁱVSP_054641	134 – 245	HTTVL…LGPSS → L in isoform 6. 1 PublicationAdd BLAST	112
Alternative sequenceⁱVSP_012316	135 – 137	TTV → FKA in isoform 5. 1 Publication	3
Alternative sequenceⁱVSP_012317	138 – 245	Missing in isoform 5. 1 PublicationAdd BLAST	108
Alternative sequenceⁱVSP_012318	227 – 245	KPPSW…LGPSS → SMEEEKEKPKLE in isoform 2, isoform 3 and isoform 4. 4 PublicationsAdd BLAST	19

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF153605 mRNA Translation: AAD41087.1 AF151861 mRNA Translation: AAD34098.1 Frameshift. AK001347 mRNA Translation: BAA91640.1 BX538067 mRNA Translation: CAD97997.1 BX640703 mRNA Translation: CAE45823.1 Different initiation. AK298533 mRNA Translation: BAG60734.1 AL023581 Genomic DNA No translation available. AL136116 Genomic DNA No translation available. AL391726 Genomic DNA No translation available. AL450335 Genomic DNA No translation available. BC025278 mRNA Translation: AAH25278.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS5198.1 [Q9NVV5-2] CCDS69215.1 [Q9NVV5-6] CCDS69216.1 [Q9NVV5-5]
NCBI Reference Sequences More...RefSeqⁱ	NP_001273516.1, NM_001286587.1 [Q9NVV5-4] NP_001273517.1, NM_001286588.1 [Q9NVV5-6] NP_001273518.1, NM_001286589.1 [Q9NVV5-5] NP_057192.2, NM_016108.3 [Q9NVV5-2]
UniGeneⁱ	Hs.567501

Genome annotation databases

Ensemblⁱ	ENST00000275235; ENSP00000275235; ENSG00000146416 [Q9NVV5-1] ENST00000357847; ENSP00000350509; ENSG00000146416 [Q9NVV5-2] ENST00000494282; ENSP00000473952; ENSG00000146416 [Q9NVV5-5] ENST00000629020; ENSP00000485875; ENSG00000146416 [Q9NVV5-6]
GeneIDⁱ	51390
KEGGⁱ	hsa:51390
UCSC genome browser More...UCSCⁱ	uc003qjg.5 human [Q9NVV5-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9NVV5	AIG1 isoform 2		PANTR		245	UniRef100_Q9NVV5
Uncharacterized protein		PANPA		245
UPI000E6E2653		HUMAN		131
Q9NVV5-2	AIG1 isoform 1		PANTR		238	UniRef100_K7DGU3
Uncharacterized protein		PANPA		238
Q9NVV5-3	AIG1 isoform 2 (Fragment)		PONAB		124	UniRef100_Q9NVV5-3
AIG1 isoform 5 (Fragment)		PANTR		124
Androgen-induced gene 1 protein (Fragment)		HUMAN		123
Q9NVV5-5	AIG1 isoform 5		PONAB		137	UniRef100_A0A2J8X9U8
AIG1 isoform 8		PANTR		137
Q9NVV5-6	AIG1 isoform 7		PANTR		134	UniRef100_A0A2I3SXN1
AIG1 isoform 4		PONAB		134
Uncharacterized protein		PANPA		134
Androgen induced 1		GORGO		134

Protein	Similar proteins		Species	Score	Length	Source
Q9NVV5	AIG1 isoform 2		PANTR		245	UniRef90_Q9NVV5
Uncharacterized protein		PANPA		245
Uncharacterized protein		MACMU		219
Uncharacterized protein (Fragment)		MACFA		200
UPI000E6E2653		HUMAN		131
+2
Q9NVV5-2	Isoform 4 of Androgen-induced gene 1 protein		HUMAN		228	UniRef90_Q9NVV5-4
Uncharacterized protein		PAPAN		282
Uncharacterized protein		CERAT		260
Uncharacterized protein		AOTNA		248
Uncharacterized protein		MACMU		245
+130
Q9NVV5-3	AIG1 isoform 2 (Fragment)		PONAB		124	UniRef90_Q9NVV5-3
AIG1 isoform 5 (Fragment)		PANTR		124
Androgen-induced gene 1 protein (Fragment)		HUMAN		123
Q9NVV5-4	Uncharacterized protein		PAPAN		282	UniRef90_Q9NVV5-4
Uncharacterized protein		CERAT		260
Uncharacterized protein		AOTNA		248
Uncharacterized protein		MACMU		245
Uncharacterized protein		MACFA		245
+130
Q9NVV5-5	Uncharacterized protein		PAPAN		137	UniRef90_A0A2I3N9G4
androgen-induced gene 1 protein isoform X2		NEOSC		138
AIG1 isoform 5		PONAB		137
AIG1 isoform 8		PANTR		137
UPI000A3251B6		MESAU		170
+14
Q9NVV5-6	AIG1 isoform 7		PANTR		134	UniRef90_A0A2I3SXN1
AIG1 isoform 4		PONAB		134
Uncharacterized protein		PANPA		134
Androgen induced 1		GORGO		134
Uncharacterized protein		MACMU		137
+24

Protein	Similar proteins		Species	Score	Length	Source
Q9NVV5	AIG1 isoform 2		PANTR		245	UniRef50_Q9NVV5
Uncharacterized protein		PANPA		245
Uncharacterized protein		MACMU		219
Uncharacterized protein (Fragment)		MACFA		200
UPI000E6E2653		HUMAN		131
+6
Q9NVV5-2	Isoform 4 of Androgen-induced gene 1 protein		HUMAN		228	UniRef50_Q9NVV5-4
Androgen-induced gene 1 protein		MOUSE		262
Uncharacterized protein		PAPAN		282
Uncharacterized protein		CERAT		260
Uncharacterized protein		AOTNA		248
+237
Q9NVV5-3	AIG1 isoform 2 (Fragment)		PONAB		124	UniRef50_Q9NVV5-3
AIG1 isoform 5 (Fragment)		PANTR		124
Androgen-induced gene 1 protein (Fragment)		HUMAN		123
Uncharacterized protein		COLVI		200
UPI000440E35E		ASTMX		203
+5
Q9NVV5-4	Androgen-induced gene 1 protein		MOUSE		262	UniRef50_Q9NVV5-4
Uncharacterized protein		PAPAN		282
Uncharacterized protein		CERAT		260
Uncharacterized protein		AOTNA		248
Uncharacterized protein		MANLE		245
+237
Q9NVV5-5	AIG1 isoform 7		PANTR		134	UniRef50_A0A2I3SXN1
AIG1 isoform 4		PONAB		134
Uncharacterized protein		PANPA		134
Androgen induced 1		GORGO		134
Isoform 6 of Androgen-induced gene 1 protein		HUMAN		134
+105
Q9NVV5-6	AIG1 isoform 7		PANTR		134	UniRef50_A0A2I3SXN1
AIG1 isoform 4		PONAB		134
Uncharacterized protein		PANPA		134
Androgen induced 1		GORGO		134
Uncharacterized protein		MACMU		137
+105

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF153605 mRNA Translation: AAD41087.1 AF151861 mRNA Translation: AAD34098.1 Frameshift. AK001347 mRNA Translation: BAA91640.1 BX538067 mRNA Translation: CAD97997.1 BX640703 mRNA Translation: CAE45823.1 Different initiation. AK298533 mRNA Translation: BAG60734.1 AL023581 Genomic DNA No translation available. AL136116 Genomic DNA No translation available. AL391726 Genomic DNA No translation available. AL450335 Genomic DNA No translation available. BC025278 mRNA Translation: AAH25278.1
CCDSⁱ	CCDS5198.1 [Q9NVV5-2] CCDS69215.1 [Q9NVV5-6] CCDS69216.1 [Q9NVV5-5]
RefSeqⁱ	NP_001273516.1, NM_001286587.1 [Q9NVV5-4] NP_001273517.1, NM_001286588.1 [Q9NVV5-6] NP_001273518.1, NM_001286589.1 [Q9NVV5-5] NP_057192.2, NM_016108.3 [Q9NVV5-2]
UniGeneⁱ	Hs.567501

3D structure databases

ProteinModelPortalⁱ	Q9NVV5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	119519, 7 interactors
IntActⁱ	Q9NVV5, 42 interactors
STRINGⁱ	9606.ENSP00000350509

Chemistry databases

BindingDBⁱ	Q9NVV5
SwissLipidsⁱ	SLP:000001682

Protein family/group databases

TCDBⁱ	9.B.203.1.1 the aig1 lipid hydrolase (aig1) family

TCDBⁱ

9.B.203.1.1 the aig1 lipid hydrolase (aig1) family

PTM databases

iPTMnetⁱ	Q9NVV5
PhosphoSitePlusⁱ	Q9NVV5

Polymorphism and mutation databases

DMDMⁱ	56748615

DMDMⁱ

56748615

Proteomic databases

EPDⁱ	Q9NVV5
MaxQBⁱ	Q9NVV5
PaxDbⁱ	Q9NVV5
PeptideAtlasⁱ	Q9NVV5
PRIDEⁱ	Q9NVV5
ProteomicsDBⁱ	82866 82867 [Q9NVV5-2] 82868 [Q9NVV5-3] 82869 [Q9NVV5-4] 82870 [Q9NVV5-5]
TopDownProteomicsⁱ	Q9NVV5-4 [Q9NVV5-4]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	51390
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000275235; ENSP00000275235; ENSG00000146416 [Q9NVV5-1] ENST00000357847; ENSP00000350509; ENSG00000146416 [Q9NVV5-2] ENST00000494282; ENSP00000473952; ENSG00000146416 [Q9NVV5-5] ENST00000629020; ENSP00000485875; ENSG00000146416 [Q9NVV5-6]
GeneIDⁱ	51390
KEGGⁱ	hsa:51390
UCSCⁱ	uc003qjg.5 human [Q9NVV5-1]

Organism-specific databases

CTDⁱ	51390
DisGeNETⁱ	51390
EuPathDBⁱ	HostDB:ENSG00000146416.16
GeneCardsⁱ	AIG1
HGNCⁱ	HGNC:21607 AIG1
HPAⁱ	HPA060766
MIMⁱ	608514 gene
neXtProtⁱ	NX_Q9NVV5
OpenTargetsⁱ	ENSG00000146416
PharmGKBⁱ	PA134991331
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3989 Eukaryota ENOG4111HQA LUCA
GeneTreeⁱ	ENSGT00390000012526
HOVERGENⁱ	HBG050468
InParanoidⁱ	Q9NVV5
OMAⁱ	HTNIVIF
OrthoDBⁱ	EOG091G0LUO
PhylomeDBⁱ	Q9NVV5
TreeFamⁱ	TF318170

Miscellaneous databases

ChiTaRSⁱ	AIG1 human
GeneWikiⁱ	AIG1
GenomeRNAiⁱ	51390
Protein Ontology More...PROⁱ	PR:Q9NVV5
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000146416 Expressed in 208 organ(s), highest expression level in liver
CleanExⁱ	HS_AIG1
ExpressionAtlasⁱ	Q9NVV5 baseline and differential
Genevisibleⁱ	Q9NVV5 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR006838 Far-17a_AIG1
PANTHERⁱ	PTHR10989 PTHR10989, 1 hit
Pfamⁱ	View protein in Pfam PF04750 Far-17a_AIG1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	AIG1_HUMAN
Accessionⁱ	Q9NVV5Primary (citable) accession number: Q9NVV5 Secondary accession number(s): B4DPX2 Q9Y5B4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 21, 2004
	Last sequence update:	December 21, 2004
	Last modified:	November 7, 2018
	This is version 129 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM

UniProtKB

UniParc

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UniRef

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Supporting data

UniProtKB - Q9NVV5 (AIG1_HUMAN)

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Androgen-induced gene 1 protein

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Protein family/group databases

Chemistry databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ