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Protein

Uncharacterized protein CCDC198

Gene

CCDC198

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein CCDC198Curated
Gene namesi
Name:CCDC198Imported
Synonyms:C14orf105
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000100557.9
HGNCiHGNC:20189 CCDC198
neXtProtiNX_Q9NVL8

Pathology & Biotechi

Organism-specific databases

DisGeNETi55195
OpenTargetsiENSG00000100557
PharmGKBiPA134868494

Polymorphism and mutation databases

BioMutaiC14orf105
DMDMi160332322

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000899131 – 296Uncharacterized protein CCDC198Add BLAST296

Proteomic databases

PaxDbiQ9NVL8
PeptideAtlasiQ9NVL8
PRIDEiQ9NVL8
ProteomicsDBi82824

PTM databases

iPTMnetiQ9NVL8
PhosphoSitePlusiQ9NVL8

Expressioni

Gene expression databases

BgeeiENSG00000100557 Expressed in 80 organ(s), highest expression level in kidney
CleanExiHS_C14orf105
ExpressionAtlasiQ9NVL8 baseline and differential
GenevisibleiQ9NVL8 HS

Organism-specific databases

HPAiHPA029202

Interactioni

Binary interactionsi

Protein-protein interaction databases

BioGridi120492, 20 interactors
IntActiQ9NVL8, 17 interactors
MINTiQ9NVL8
STRINGi9606.ENSP00000216445

Structurei

3D structure databases

ProteinModelPortaliQ9NVL8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IE4S Eukaryota
ENOG410YY0W LUCA
GeneTreeiENSGT00390000001071
HOGENOMiHOG000024829
HOVERGENiHBG081272
InParanoidiQ9NVL8
PhylomeDBiQ9NVL8
TreeFamiTF336148

Family and domain databases

InterProiView protein in InterPro
IPR029235 DUF4619
PANTHERiPTHR16065 PTHR16065, 1 hit
PfamiView protein in Pfam
PF15398 DUF4619, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q9NVL8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLSHSKTHL RVIKVAPLQN KEVETPSAGR VDFAFNQNLE EKTSYSLARL
60 70 80 90 100
QDQNKALEGQ LPPLQENWYG RYSTASRDMY FDIPLEHRET SIIKRHPPQR
110 120 130 140 150
LQKLEPIDLP RVITSGRLLS QREARTMHKA KQVLEKKMQT PMYTSENRQY
160 170 180 190 200
LHKMQVLEMI RKRQEAQMEL KKSLHGEARI NKQSPRDHKA KKTLQSTPRN
210 220 230 240 250
DDHDLLTMLP DEILNRGPGN SKNTEFLKHQ AVNNYCPWKI GKMETWLHEQ
260 270 280 290
EAQGQLLWDS SSSDSDEQGK DEKKPRALVR TRTERIPLFD EFFDQE
Length:296
Mass (Da):34,690
Last modified:November 13, 2007 - v2
Checksum:i6718547F055B1C49
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q05C89Q05C89_HUMAN
C14orf105 protein
CCDC198 C14orf105
74Annotation score:
F5GWJ3F5GWJ3_HUMAN
Uncharacterized protein CCDC198
CCDC198
336Annotation score:
E9PSE9E9PSE9_HUMAN
Uncharacterized protein CCDC198
CCDC198
295Annotation score:
E9PI50E9PI50_HUMAN
Uncharacterized protein CCDC198
CCDC198
104Annotation score:
H0YES7H0YES7_HUMAN
Uncharacterized protein CCDC198
CCDC198
136Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti132Missing in AAI17406 (PubMed:15489334).Curated1
Sequence conflicti132Missing in AAI43567 (PubMed:15489334).Curated1
Sequence conflicti132Missing in EAW80707 (Ref. 4) Curated1
Sequence conflicti223N → D in BAA91732 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_024310235Y → C4 PublicationsCorresponds to variant dbSNP:rs1152530Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001512 mRNA Translation: BAA91732.1
AK223127 mRNA Translation: BAD96847.1
AL161804 Genomic DNA No translation available.
AL355834 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW80707.1
BC117405 mRNA Translation: AAI17406.1
BC143566 mRNA Translation: AAI43567.1
CCDSiCCDS9730.1
RefSeqiNP_001269985.1, NM_001283056.1
NP_001269986.1, NM_001283057.1
NP_001269987.1, NM_001283058.1
NP_001269988.1, NM_001283059.1
NP_060638.2, NM_018168.3
UniGeneiHs.659706

Genome annotation databases

EnsembliENST00000216445; ENSP00000216445; ENSG00000100557
GeneIDi55195
KEGGihsa:55195
UCSCiuc001xcy.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001512 mRNA Translation: BAA91732.1
AK223127 mRNA Translation: BAD96847.1
AL161804 Genomic DNA No translation available.
AL355834 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW80707.1
BC117405 mRNA Translation: AAI17406.1
BC143566 mRNA Translation: AAI43567.1
CCDSiCCDS9730.1
RefSeqiNP_001269985.1, NM_001283056.1
NP_001269986.1, NM_001283057.1
NP_001269987.1, NM_001283058.1
NP_001269988.1, NM_001283059.1
NP_060638.2, NM_018168.3
UniGeneiHs.659706

3D structure databases

ProteinModelPortaliQ9NVL8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120492, 20 interactors
IntActiQ9NVL8, 17 interactors
MINTiQ9NVL8
STRINGi9606.ENSP00000216445

PTM databases

iPTMnetiQ9NVL8
PhosphoSitePlusiQ9NVL8

Polymorphism and mutation databases

BioMutaiC14orf105
DMDMi160332322

Proteomic databases

PaxDbiQ9NVL8
PeptideAtlasiQ9NVL8
PRIDEiQ9NVL8
ProteomicsDBi82824

Protocols and materials databases

DNASUi55195
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000216445; ENSP00000216445; ENSG00000100557
GeneIDi55195
KEGGihsa:55195
UCSCiuc001xcy.4 human

Organism-specific databases

CTDi55195
DisGeNETi55195
EuPathDBiHostDB:ENSG00000100557.9
GeneCardsiCCDC198
HGNCiHGNC:20189 CCDC198
HPAiHPA029202
neXtProtiNX_Q9NVL8
OpenTargetsiENSG00000100557
PharmGKBiPA134868494
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IE4S Eukaryota
ENOG410YY0W LUCA
GeneTreeiENSGT00390000001071
HOGENOMiHOG000024829
HOVERGENiHBG081272
InParanoidiQ9NVL8
PhylomeDBiQ9NVL8
TreeFamiTF336148

Miscellaneous databases

GenomeRNAii55195
PROiPR:Q9NVL8

Gene expression databases

BgeeiENSG00000100557 Expressed in 80 organ(s), highest expression level in kidney
CleanExiHS_C14orf105
ExpressionAtlasiQ9NVL8 baseline and differential
GenevisibleiQ9NVL8 HS

Family and domain databases

InterProiView protein in InterPro
IPR029235 DUF4619
PANTHERiPTHR16065 PTHR16065, 1 hit
PfamiView protein in Pfam
PF15398 DUF4619, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCC198_HUMAN
AccessioniPrimary (citable) accession number: Q9NVL8
Secondary accession number(s): Q17R99, Q53G04
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: November 13, 2007
Last modified: September 12, 2018
This is version 97 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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