UniProtKB - Q9NVI1 (FANCI_HUMAN)
Protein
Fanconi anemia group I protein
Gene
FANCI
Organism
Homo sapiens (Human)
Status
Functioni
Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.4 Publications
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA polymerase binding Source: UniProtKB
GO - Biological processi
- cell cycle Source: UniProtKB-KW
- interstrand cross-link repair Source: Reactome
- positive regulation of protein ubiquitination Source: MGI
Keywordsi
Molecular function | DNA-binding |
Biological process | Cell cycle, DNA damage, DNA repair |
Enzyme and pathway databases
PathwayCommonsi | Q9NVI1 |
Reactomei | R-HSA-6783310, Fanconi Anemia Pathway R-HSA-6796648, TP53 Regulates Transcription of DNA Repair Genes |
SIGNORi | Q9NVI1 |
Names & Taxonomyi
Protein namesi | Recommended name: Fanconi anemia group I proteinShort name: Protein FACI |
Gene namesi | Name:FANCI Synonyms:KIAA1794 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:25568, FANCI |
MIMi | 611360, gene |
neXtProti | NX_Q9NVI1 |
VEuPathDBi | HostDB:ENSG00000140525.17 |
Subcellular locationi
Nucleus
- Nucleus 3 Publications
Other locations
- Cytoplasm 1 Publication
Note: Observed in spots localized in pairs on the sister chromatids of mitotic chromosome arms and not centromeres, one on each chromatids. These foci coincide with common fragile sites. They are frequently interlinked through BLM-associated ultra-fine DNA bridges.
Cytosol
- cytosol Source: HPA
Nucleus
- nucleoplasm Source: HPA
Other locations
Keywords - Cellular componenti
Cytoplasm, NucleusPathology & Biotechi
Involvement in diseasei
Fanconi anemia complementation group I (FANCI)3 Publications
The disease is caused by variants affecting the gene represented in this entry.
Disease descriptionA disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
Related information in OMIMFeature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_032689 | 55 | P → L in FANCI; benign variant; no effect on ubiquitination and DNA repair. 2 PublicationsCorresponds to variant dbSNP:rs62020347EnsemblClinVar. | 1 | |
Natural variantiVAR_032691 | 858 | H → Y in FANCI. 1 Publication | 1 | |
Natural variantiVAR_032692 | 1285 | R → Q in FANCI; abolishes function in DNA repair. 2 PublicationsCorresponds to variant dbSNP:rs121918163Ensembl. | 1 |
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 523 | K → R: Abolishes monoubiquitination by FANCL and UBE2T. 1 Publication | 1 |
Keywords - Diseasei
Disease variant, Fanconi anemiaOrganism-specific databases
DisGeNETi | 55215 |
GeneReviewsi | FANCI |
MalaCardsi | FANCI |
MIMi | 609053, phenotype |
OpenTargetsi | ENSG00000140525 |
Orphaneti | 84, Fanconi anemia |
PharmGKBi | PA162387928 |
Miscellaneous databases
Pharosi | Q9NVI1, Tbio |
Genetic variation databases
BioMutai | FANCI |
DMDMi | 212276518 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000248376 | 1 – 1328 | Fanconi anemia group I proteinAdd BLAST | 1328 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 407 | PhosphoserineCombined sources | 1 | |
Cross-linki | 523 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)3 Publications | ||
Modified residuei | 556 | PhosphoserineBy similarity | 1 | |
Modified residuei | 730 | Phosphoserine1 Publication | 1 | |
Modified residuei | 952 | Phosphothreonine1 Publication | 1 | |
Modified residuei | 1121 | Phosphoserine1 Publication | 1 |
Post-translational modificationi
Monoubiquitinated by FANCL on Lys-523 during S phase and upon genotoxic stress. Deubiquitinated by USP1 as cells enter G2/M, or once DNA repair is completed. Monoubiquitination requires the FANCA-FANCB-FANCC-FANCE-FANCF-FANCG-FANCM complex. Ubiquitination is required for binding to chromatin, DNA repair, and normal cell cycle progression. Monoubiquitination is stimulated by DNA-binding.3 Publications
Phosphorylated in response to DNA damage by ATM and/or ATR.1 Publication
Keywords - PTMi
Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
CPTACi | CPTAC-3283 |
EPDi | Q9NVI1 |
jPOSTi | Q9NVI1 |
MassIVEi | Q9NVI1 |
PaxDbi | Q9NVI1 |
PeptideAtlasi | Q9NVI1 |
PRIDEi | Q9NVI1 |
ProteomicsDBi | 82811 [Q9NVI1-3] 82812 [Q9NVI1-1] 82813 [Q9NVI1-2] 82814 [Q9NVI1-4] |
PTM databases
iPTMneti | Q9NVI1 |
PhosphoSitePlusi | Q9NVI1 |
SwissPalmi | Q9NVI1 |
Expressioni
Gene expression databases
Bgeei | ENSG00000140525, Expressed in testis and 182 other tissues |
ExpressionAtlasi | Q9NVI1, baseline and differential |
Genevisiblei | Q9NVI1, HS |
Organism-specific databases
HPAi | ENSG00000140525, Tissue enhanced (lymphoid tissue, testis) |
Interactioni
Subunit structurei
Binary interactionsi
Q9NVI1
With | #Exp. | IntAct |
---|---|---|
FANCD2 [Q9BXW9] | 2 | EBI-1013291,EBI-359343 |
GO - Molecular functioni
- DNA polymerase binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 120511, 122 interactors |
CORUMi | Q9NVI1 |
DIPi | DIP-29381N |
IntActi | Q9NVI1, 61 interactors |
MINTi | Q9NVI1 |
STRINGi | 9606.ENSP00000310842 |
Miscellaneous databases
RNActi | Q9NVI1, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q9NVI1 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domaini
The C-terminal 30 residues are probably required for function in DNA repair.
Phylogenomic databases
eggNOGi | KOG4553, Eukaryota |
GeneTreei | ENSGT00390000005855 |
HOGENOMi | CLU_1102483_0_0_1 |
InParanoidi | Q9NVI1 |
OMAi | DMCSNST |
OrthoDBi | 169407at2759 |
PhylomeDBi | Q9NVI1 |
TreeFami | TF323694 |
Family and domain databases
CDDi | cd11720, FANCI, 1 hit |
InterProi | View protein in InterPro IPR026171, FANCI IPR029310, FANCI_HD1 IPR029312, FANCI_HD2 IPR029308, FANCI_S1 IPR029305, FANCI_S1-cap IPR029315, FANCI_S2 IPR029313, FANCI_S3 IPR029314, FANCI_S4 |
PANTHERi | PTHR21818, PTHR21818, 1 hit |
Pfami | View protein in Pfam PF14679, FANCI_HD1, 1 hit PF14680, FANCI_HD2, 1 hit PF14675, FANCI_S1, 1 hit PF14674, FANCI_S1-cap, 1 hit PF14676, FANCI_S2, 1 hit PF14677, FANCI_S3, 1 hit PF14678, FANCI_S4, 1 hit |
s (4+)i Sequence
Sequence statusi: Complete.
This entry describes 4 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 4 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All
Isoform 3 (identifier: Q9NVI1-3) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MDQKILSLAA EKTADKLQEF LQTLREGDLT NLLQNQAVKG KVAGALLRAI
60 70 80 90 100
FKGSPCSEEA GTLRRRKIYT CCIQLVESGD LQKEIASEII GLLMLEAHHF
110 120 130 140 150
PGPLLVELAN EFISAVREGS LVNGKSLELL PIILTALATK KENLAYGKGV
160 170 180 190 200
LSGEECKKQL INTLCSGRWD QQYVIQLTSM FKDVPLTAEE VEFVVEKALS
210 220 230 240 250
MFSKMNLQEI PPLVYQLLVL SSKGSRKSVL EGIIAFFSAL DKQHNEEQSG
260 270 280 290 300
DELLDVVTVP SGELRHVEGT IILHIVFAIK LDYELGRELV KHLKVGQQGD
310 320 330 340 350
SNNNLSPFSI ALLLSVTRIQ RFQDQVLDLL KTSVVKSFKD LQLLQGSKFL
360 370 380 390 400
QNLVPHRSYV STMILEVVKN SVHSWDHVTQ GLVELGFILM DSYGPKKVLD
410 420 430 440 450
GKTIETSPSL SRMPNQHACK LGANILLETF KIHEMIRQEI LEQVLNRVVT
460 470 480 490 500
RASSPISHFL DLLSNIVMYA PLVLQSCSSK VTEAFDYLSF LPLQTVQRLL
510 520 530 540 550
KAVQPLLKVS MSMRDCLILV LRKAMFANQL DARKSAVAGF LLLLKNFKVL
560 570 580 590 600
GSLSSSQCSQ SLSVSQVHVD VHSHYNSVAN ETFCLEIMDS LRRCLSQQAD
610 620 630 640 650
VRLMLYEGFY DVLRRNSQLA NSVMQTLLSQ LKQFYEPKPD LLPPLKLEAC
660 670 680 690 700
ILTQGDKISL QEPLDYLLCC IQHCLAWYKN TVIPLQQGEE EEEEEEAFYE
710 720 730 740 750
DLDDILESIT NRMIKSELED FELDKSADFS QSTSIGIKNN ICAFLVMGVC
760 770 780 790 800
EVLIEYNFSI SSFSKNRFED ILSLFMCYKK LSDILNEKAG KAKTKMANKT
810 820 830 840 850
SDSLLSMKFV SSLLTALFRD SIQSHQESLS VLRSSNEFMR YAVNVALQKV
860 870 880 890 900
QQLKETGHVS GPDGQNPEKI FQNLCDITRV LLWRYTSIPT SVEESGKKEK
910 920 930 940 950
GKSISLLCLE GLQKIFSAVQ QFYQPKIQQF LRALDVTDKE GEEREDADVS
960 970 980 990 1000
VTQRTAFQIR QFQRSLLNLL SSQEEDFNSK EALLLVTVLT SLSKLLEPSS
1010 1020 1030 1040 1050
PQFVQMLSWT SKICKENSRE DALFCKSLMN LLFSLHVSYK SPVILLRDLS
1060 1070 1080 1090 1100
QDIHGHLGDI DQDVEVEKTN HFAIVNLRTA APTVCLLVLS QAEKVLEEVD
1110 1120 1130 1140 1150
WLITKLKGQV SQETLSEEAS SQATLPNQPV EKAIIMQLGT LLTFFHELVQ
1160 1170 1180 1190 1200
TALPSGSCVD TLLKDLCKMY TTLTALVRYY LQVCQSSGGI PKNMEKLVKL
1210 1220 1230 1240 1250
SGSHLTPLCY SFISYVQNKS KSLNYTGEKK EKPAAVATAM ARVLRETKPI
1260 1270 1280 1290 1300
PNLIFAIEQY EKFLIHLSKK SKVNLMQHMK LSTSRDFKIK GNILDMVLRE
1310 1320
DGEDENEEGT ASEHGGQNKE PAKKKRKK
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH3BP78 | H3BP78_HUMAN | Fanconi anemia group I protein | FANCI | 1,090 | Annotation score: | ||
H3BMG4 | H3BMG4_HUMAN | Fanconi anemia group I protein | FANCI | 226 | Annotation score: | ||
H3BN35 | H3BN35_HUMAN | Fanconi anemia group I protein | FANCI | 145 | Annotation score: | ||
H3BQE2 | H3BQE2_HUMAN | Fanconi anemia group I protein | FANCI | 157 | Annotation score: | ||
H3BT54 | H3BT54_HUMAN | Fanconi anemia group I protein | FANCI | 215 | Annotation score: | ||
F8W7R3 | F8W7R3_HUMAN | Fanconi anemia group I protein | FANCI | 1,095 | Annotation score: | ||
H3BS60 | H3BS60_HUMAN | Fanconi anemia group I protein | FANCI | 125 | Annotation score: | ||
A0A6Q8PGF4 | A0A6Q8PGF4_HUMAN | Fanconi anemia group I protein | FANCI | 1,314 | Annotation score: | ||
A0A6Q8PH09 | A0A6Q8PH09_HUMAN | Fanconi anemia group I protein | FANCI | 1,372 | Annotation score: |
Sequence cautioni
The sequence AAH04277 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAA91770 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAB55200 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 528 | N → S in BAB47423 (PubMed:11347906).Curated | 1 | |
Sequence conflicti | 604 | M → T in BAA91770 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 877 | I → L in BAB47423 (PubMed:11347906).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_032689 | 55 | P → L in FANCI; benign variant; no effect on ubiquitination and DNA repair. 2 PublicationsCorresponds to variant dbSNP:rs62020347EnsemblClinVar. | 1 | |
Natural variantiVAR_032690 | 86 | A → V1 PublicationCorresponds to variant dbSNP:rs17803620EnsemblClinVar. | 1 | |
Natural variantiVAR_027278 | 686 | Q → K. Corresponds to variant dbSNP:rs28378332EnsemblClinVar. | 1 | |
Natural variantiVAR_027279 | 742 | C → S2 PublicationsCorresponds to variant dbSNP:rs2283432EnsemblClinVar. | 1 | |
Natural variantiVAR_032691 | 858 | H → Y in FANCI. 1 Publication | 1 | |
Natural variantiVAR_032692 | 1285 | R → Q in FANCI; abolishes function in DNA repair. 2 PublicationsCorresponds to variant dbSNP:rs121918163Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_035606 | 253 – 1328 | Missing in isoform 4. 1 PublicationAdd BLAST | 1076 | |
Alternative sequenceiVSP_026069 | 819 – 878 | Missing in isoform 1 and isoform 2. 1 PublicationAdd BLAST | 60 | |
Alternative sequenceiVSP_020257 | 1117 | Missing in isoform 2. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EF469766 mRNA Translation: ABP88002.1 EF567077 mRNA Translation: ABQ63084.1 AC124068 Genomic DNA No translation available. BC004277 mRNA Translation: AAH04277.1 Different initiation. BC140769 mRNA Translation: AAI40770.1 AK001581 mRNA Translation: BAA91770.1 Different initiation. AK027564 mRNA Translation: BAB55200.1 Different initiation. AB058697 mRNA Translation: BAB47423.1 |
CCDSi | CCDS10349.2 [Q9NVI1-1] CCDS45346.1 [Q9NVI1-3] |
RefSeqi | NP_001106849.1, NM_001113378.1 [Q9NVI1-3] NP_060663.2, NM_018193.2 [Q9NVI1-1] XP_011520058.1, XM_011521756.2 [Q9NVI1-3] XP_011520059.1, XM_011521757.2 XP_011520066.1, XM_011521764.2 [Q9NVI1-1] |
Genome annotation databases
Ensembli | ENST00000300027; ENSP00000300027; ENSG00000140525 [Q9NVI1-1] ENST00000310775; ENSP00000310842; ENSG00000140525 [Q9NVI1-3] ENST00000567996; ENSP00000458024; ENSG00000140525 [Q9NVI1-4] |
GeneIDi | 55215 |
KEGGi | hsa:55215 |
UCSCi | uc002bnm.2, human [Q9NVI1-3] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
Fanconi Anemia Mutation Database |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EF469766 mRNA Translation: ABP88002.1 EF567077 mRNA Translation: ABQ63084.1 AC124068 Genomic DNA No translation available. BC004277 mRNA Translation: AAH04277.1 Different initiation. BC140769 mRNA Translation: AAI40770.1 AK001581 mRNA Translation: BAA91770.1 Different initiation. AK027564 mRNA Translation: BAB55200.1 Different initiation. AB058697 mRNA Translation: BAB47423.1 |
CCDSi | CCDS10349.2 [Q9NVI1-1] CCDS45346.1 [Q9NVI1-3] |
RefSeqi | NP_001106849.1, NM_001113378.1 [Q9NVI1-3] NP_060663.2, NM_018193.2 [Q9NVI1-1] XP_011520058.1, XM_011521756.2 [Q9NVI1-3] XP_011520059.1, XM_011521757.2 XP_011520066.1, XM_011521764.2 [Q9NVI1-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6VAA | electron microscopy | 3.35 | A | 1-1328 | [»] | |
6VAD | electron microscopy | 3.35 | A | 1-1328 | [»] | |
6VAE | electron microscopy | 3.50 | A | 1-1328 | [»] | |
6VAF | electron microscopy | 3.90 | A | 1-1328 | [»] | |
SMRi | Q9NVI1 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 120511, 122 interactors |
CORUMi | Q9NVI1 |
DIPi | DIP-29381N |
IntActi | Q9NVI1, 61 interactors |
MINTi | Q9NVI1 |
STRINGi | 9606.ENSP00000310842 |
PTM databases
iPTMneti | Q9NVI1 |
PhosphoSitePlusi | Q9NVI1 |
SwissPalmi | Q9NVI1 |
Genetic variation databases
BioMutai | FANCI |
DMDMi | 212276518 |
Proteomic databases
CPTACi | CPTAC-3283 |
EPDi | Q9NVI1 |
jPOSTi | Q9NVI1 |
MassIVEi | Q9NVI1 |
PaxDbi | Q9NVI1 |
PeptideAtlasi | Q9NVI1 |
PRIDEi | Q9NVI1 |
ProteomicsDBi | 82811 [Q9NVI1-3] 82812 [Q9NVI1-1] 82813 [Q9NVI1-2] 82814 [Q9NVI1-4] |
Protocols and materials databases
Antibodypediai | 15714, 122 antibodies |
DNASUi | 55215 |
Genome annotation databases
Ensembli | ENST00000300027; ENSP00000300027; ENSG00000140525 [Q9NVI1-1] ENST00000310775; ENSP00000310842; ENSG00000140525 [Q9NVI1-3] ENST00000567996; ENSP00000458024; ENSG00000140525 [Q9NVI1-4] |
GeneIDi | 55215 |
KEGGi | hsa:55215 |
UCSCi | uc002bnm.2, human [Q9NVI1-3] |
Organism-specific databases
CTDi | 55215 |
DisGeNETi | 55215 |
GeneCardsi | FANCI |
GeneReviewsi | FANCI |
HGNCi | HGNC:25568, FANCI |
HPAi | ENSG00000140525, Tissue enhanced (lymphoid tissue, testis) |
MalaCardsi | FANCI |
MIMi | 609053, phenotype 611360, gene |
neXtProti | NX_Q9NVI1 |
OpenTargetsi | ENSG00000140525 |
Orphaneti | 84, Fanconi anemia |
PharmGKBi | PA162387928 |
VEuPathDBi | HostDB:ENSG00000140525.17 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG4553, Eukaryota |
GeneTreei | ENSGT00390000005855 |
HOGENOMi | CLU_1102483_0_0_1 |
InParanoidi | Q9NVI1 |
OMAi | DMCSNST |
OrthoDBi | 169407at2759 |
PhylomeDBi | Q9NVI1 |
TreeFami | TF323694 |
Enzyme and pathway databases
PathwayCommonsi | Q9NVI1 |
Reactomei | R-HSA-6783310, Fanconi Anemia Pathway R-HSA-6796648, TP53 Regulates Transcription of DNA Repair Genes |
SIGNORi | Q9NVI1 |
Miscellaneous databases
BioGRID-ORCSi | 55215, 91 hits in 879 CRISPR screens |
ChiTaRSi | FANCI, human |
GeneWikii | FANCI |
GenomeRNAii | 55215 |
Pharosi | Q9NVI1, Tbio |
PROi | PR:Q9NVI1 |
RNActi | Q9NVI1, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000140525, Expressed in testis and 182 other tissues |
ExpressionAtlasi | Q9NVI1, baseline and differential |
Genevisiblei | Q9NVI1, HS |
Family and domain databases
CDDi | cd11720, FANCI, 1 hit |
InterProi | View protein in InterPro IPR026171, FANCI IPR029310, FANCI_HD1 IPR029312, FANCI_HD2 IPR029308, FANCI_S1 IPR029305, FANCI_S1-cap IPR029315, FANCI_S2 IPR029313, FANCI_S3 IPR029314, FANCI_S4 |
PANTHERi | PTHR21818, PTHR21818, 1 hit |
Pfami | View protein in Pfam PF14679, FANCI_HD1, 1 hit PF14680, FANCI_HD2, 1 hit PF14675, FANCI_S1, 1 hit PF14674, FANCI_S1-cap, 1 hit PF14676, FANCI_S2, 1 hit PF14677, FANCI_S3, 1 hit PF14678, FANCI_S4, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FANCI_HUMAN | |
Accessioni | Q9NVI1Primary (citable) accession number: Q9NVI1 Secondary accession number(s): A4ZVE4 Q9BT96 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 5, 2006 |
Last sequence update: | November 4, 2008 | |
Last modified: | February 10, 2021 | |
This is version 160 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human chromosome 15
Human chromosome 15: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references