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Entry version 147 (02 Dec 2020)
Sequence version 2 (10 Oct 2003)
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Protein

Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

Gene

PCMTD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei64By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NV79

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PCMTD2
Synonyms:C20orf36
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...
EuPathDBi
HostDB:ENSG00000203880.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15882, PCMTD2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NV79

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55251

Open Targets

More...
OpenTargetsi
ENSG00000203880

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25750

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NV79, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PCMTD2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
41688812

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedSequence analysis
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001119272 – 361Protein-L-isoaspartate O-methyltransferase domain-containing protein 2Add BLAST360

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi2N-myristoyl glycineSequence analysis1

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NV79

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NV79

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NV79

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NV79

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NV79

PeptideAtlas

More...
PeptideAtlasi
Q9NV79

PRoteomics IDEntifications database

More...
PRIDEi
Q9NV79

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
82757 [Q9NV79-1]
82758 [Q9NV79-2]
82759 [Q9NV79-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NV79

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NV79

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000203880, Expressed in pigmented layer of retina and 242 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NV79, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NV79, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000203880, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120542, 21 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NV79, 7 interactors

Molecular INTeraction database

More...
MINTi
Q9NV79

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000307854

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NV79, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NV79

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi279 – 286Poly-Arg8

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1661, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183032

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_029295_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NV79

Database of Orthologous Groups

More...
OrthoDBi
1560133at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NV79

TreeFam database of animal gene trees

More...
TreeFami
TF329329

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000682, PCMT
IPR029063, SAM-dependent_MTases

The PANTHER Classification System

More...
PANTHERi
PTHR11579, PTHR11579, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53335, SSF53335, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NV79-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGGAVSAGED NDELIDNLKE AQYIRTELVE QAFRAIDRAD YYLEEFKENA
60 70 80 90 100
YKDLAWKHGN IHLSAPCIYS EVMEALDLQP GLSFLNLGSG TGYLSSMVGL
110 120 130 140 150
ILGPFGVNHG VELHSDVIEY AKQKLDFFIR TSDSFDKFDF CEPSFVTGNC
160 170 180 190 200
LEISPDCSQY DRVYCGAGVQ KEHEEYMKNL LKVGGILVMP LEEKLTKITR
210 220 230 240 250
TGPSAWETKK ILAVSFAPLI QPCHSESGKS RLVQLPPVAV RSLQDLARIA
260 270 280 290 300
IRGTIKKIIH QETVSKNGNG LKNTPRFKRR RVRRRRMETI VFLDKEVFAS
310 320 330 340 350
RISNPSDDNS CEDLEEERRE EEEKTPPETK PDPPVNFLRQ KVLSLPLPDP
360
LKYYLLYYRE K
Length:361
Mass (Da):41,072
Last modified:October 10, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCC239150135E0A1B
GO
Isoform 2 (identifier: Q9NV79-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     195-221: Missing.

Show »
Length:334
Mass (Da):38,119
Checksum:i22C856548611940C
GO
Isoform 3 (identifier: Q9NV79-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-224: Missing.
     225-236: SESGKSRLVQLP → MLRFCAGLSDFA

Show »
Length:137
Mass (Da):16,089
Checksum:i7897444B539D1764
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JM70A0A0G2JM70_HUMAN
Protein-L-isoaspartate O-methyltran...
PCMTD2
262Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W9F3F8W9F3_HUMAN
Protein-L-isoaspartate O-methyltran...
PCMTD2
282Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GYL1V9GYL1_HUMAN
Protein-L-isoaspartate O-methyltran...
PCMTD2
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GYZ7V9GYZ7_HUMAN
Protein-L-isoaspartate O-methyltran...
PCMTD2
135Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GYZ4V9GYZ4_HUMAN
Protein-L-isoaspartate O-methyltran...
PCMTD2
71Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GYG6V9GYG6_HUMAN
Protein-L-isoaspartate O-methyltran...
PCMTD2
183Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GZ41V9GZ41_HUMAN
Protein-L-isoaspartate O-methyltran...
PCMTD2
211Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JR02A0A0G2JR02_HUMAN
Protein-L-isoaspartate O-methyltran...
PCMTD2
31Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti12D → E in BAA91877 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0085461 – 224Missing in isoform 3. 1 PublicationAdd BLAST224
Alternative sequenceiVSP_008547195 – 221Missing in isoform 2. 1 PublicationAdd BLAST27
Alternative sequenceiVSP_008548225 – 236SESGK…LVQLP → MLRFCAGLSDFA in isoform 3. 1 PublicationAdd BLAST12

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK001745 mRNA Translation: BAA91877.1
AK126700 mRNA Translation: BAC86648.1
AL121581 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75152.1
CH471077 Genomic DNA Translation: EAW75153.1
BC033665 mRNA Translation: AAH33665.1
BC040945 mRNA Translation: AAH40945.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13559.1 [Q9NV79-1]
CCDS46631.1 [Q9NV79-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001098395.1, NM_001104925.1 [Q9NV79-2]
NP_060727.2, NM_018257.2 [Q9NV79-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000308824; ENSP00000307854; ENSG00000203880 [Q9NV79-1]
ENST00000369758; ENSP00000358773; ENSG00000203880 [Q9NV79-2]
ENST00000615818; ENSP00000482166; ENSG00000280663 [Q9NV79-1]
ENST00000627415; ENSP00000486510; ENSG00000280663 [Q9NV79-1]
ENST00000631244; ENSP00000486003; ENSG00000280663 [Q9NV79-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55251

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55251

UCSC genome browser

More...
UCSCi
uc002yil.5, human [Q9NV79-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001745 mRNA Translation: BAA91877.1
AK126700 mRNA Translation: BAC86648.1
AL121581 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75152.1
CH471077 Genomic DNA Translation: EAW75153.1
BC033665 mRNA Translation: AAH33665.1
BC040945 mRNA Translation: AAH40945.1
CCDSiCCDS13559.1 [Q9NV79-1]
CCDS46631.1 [Q9NV79-2]
RefSeqiNP_001098395.1, NM_001104925.1 [Q9NV79-2]
NP_060727.2, NM_018257.2 [Q9NV79-1]

3D structure databases

SMRiQ9NV79
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120542, 21 interactors
IntActiQ9NV79, 7 interactors
MINTiQ9NV79
STRINGi9606.ENSP00000307854

PTM databases

iPTMnetiQ9NV79
PhosphoSitePlusiQ9NV79

Polymorphism and mutation databases

BioMutaiPCMTD2
DMDMi41688812

Proteomic databases

EPDiQ9NV79
jPOSTiQ9NV79
MassIVEiQ9NV79
MaxQBiQ9NV79
PaxDbiQ9NV79
PeptideAtlasiQ9NV79
PRIDEiQ9NV79
ProteomicsDBi82757 [Q9NV79-1]
82758 [Q9NV79-2]
82759 [Q9NV79-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
30018, 82 antibodies

The DNASU plasmid repository

More...
DNASUi
55251

Genome annotation databases

EnsembliENST00000308824; ENSP00000307854; ENSG00000203880 [Q9NV79-1]
ENST00000369758; ENSP00000358773; ENSG00000203880 [Q9NV79-2]
ENST00000615818; ENSP00000482166; ENSG00000280663 [Q9NV79-1]
ENST00000627415; ENSP00000486510; ENSG00000280663 [Q9NV79-1]
ENST00000631244; ENSP00000486003; ENSG00000280663 [Q9NV79-2]
GeneIDi55251
KEGGihsa:55251
UCSCiuc002yil.5, human [Q9NV79-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
55251
DisGeNETi55251
EuPathDBiHostDB:ENSG00000203880.11

GeneCards: human genes, protein and diseases

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GeneCardsi
PCMTD2
HGNCiHGNC:15882, PCMTD2
HPAiENSG00000203880, Low tissue specificity
neXtProtiNX_Q9NV79
OpenTargetsiENSG00000203880
PharmGKBiPA25750

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1661, Eukaryota
GeneTreeiENSGT00950000183032
HOGENOMiCLU_029295_0_0_1
InParanoidiQ9NV79
OrthoDBi1560133at2759
PhylomeDBiQ9NV79
TreeFamiTF329329

Enzyme and pathway databases

PathwayCommonsiQ9NV79

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
55251, 15 hits in 843 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
PCMTD2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55251
PharosiQ9NV79, Tdark

Protein Ontology

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PROi
PR:Q9NV79
RNActiQ9NV79, protein

Gene expression databases

BgeeiENSG00000203880, Expressed in pigmented layer of retina and 242 other tissues
ExpressionAtlasiQ9NV79, baseline and differential
GenevisibleiQ9NV79, HS

Family and domain databases

InterProiView protein in InterPro
IPR000682, PCMT
IPR029063, SAM-dependent_MTases
PANTHERiPTHR11579, PTHR11579, 1 hit
SUPFAMiSSF53335, SSF53335, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPCMD2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NV79
Secondary accession number(s): E1P5H3, Q8IW60, Q9H4K2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 10, 2003
Last modified: December 2, 2020
This is version 147 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
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