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Protein

Proline-rich protein 34

Gene

PRR34

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Proline-rich protein 34
Gene namesi
Name:PRR34
Synonyms:C22orf26
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000182257.6
HGNCiHGNC:25606 PRR34
neXtProtiNX_Q9NV39

Pathology & Biotechi

Organism-specific databases

DisGeNETi55267
OpenTargetsiENSG00000182257
PharmGKBiPA145149369

Polymorphism and mutation databases

BioMutaiC22orf26

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002711081 – 138Proline-rich protein 34Add BLAST138

Proteomic databases

PaxDbiQ9NV39
PRIDEiQ9NV39
ProteomicsDBi82744

Expressioni

Gene expression databases

BgeeiENSG00000182257 Expressed in 84 organ(s), highest expression level in uterus
CleanExiHS_C22orf26
ExpressionAtlasiQ9NV39 baseline and differential
GenevisibleiQ9NV39 HS

Interactioni

Binary interactionsi

Protein-protein interaction databases

IntActiQ9NV39, 13 interactors
STRINGi9606.ENSP00000327764

Structurei

3D structure databases

ProteinModelPortaliQ9NV39
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi12 – 87Pro-richAdd BLAST76

Phylogenomic databases

eggNOGiENOG410KHG1 Eukaryota
ENOG4110RAD LUCA
GeneTreeiENSGT00410000029629
HOGENOMiHOG000038015
HOVERGENiHBG081381
InParanoidiQ9NV39
OMAiLTFWAPG
OrthoDBiEOG091G15WS
PhylomeDBiQ9NV39
TreeFamiTF341481

Sequencei

Sequence statusi: Complete.

Q9NV39-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPASATAAWH CPPLCLPPLP ASAPTSPPNP ATRPAPGPGR RARCPQSAHP
60 70 80 90 100
APTRGALTFW APGSWPRVLL VPRSPGPVLR APRLPHPAAR ARRRAWHGAR
110 120 130
LPGSPARAGR TFQRGLVSNS WAHAIFLPRP PNVLELQV
Length:138
Mass (Da):14,718
Last modified:October 1, 2000 - v1
Checksum:iB1737A3C8DCFDDCD
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_06163528P → L. Corresponds to variant dbSNP:rs12159707Ensembl.1
Natural variantiVAR_061636137Q → R. Corresponds to variant dbSNP:rs59929908Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001807 mRNA Translation: BAA91920.1
AL121672 Genomic DNA No translation available.
CH471138 Genomic DNA Translation: EAW73396.1
CCDSiCCDS14071.1
RefSeqiNP_060750.1, NM_018280.2
UniGeneiHs.567529

Genome annotation databases

EnsembliENST00000396008; ENSP00000379329; ENSG00000182257
GeneIDi55267
KEGGihsa:55267
UCSCiuc003bgq.2 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001807 mRNA Translation: BAA91920.1
AL121672 Genomic DNA No translation available.
CH471138 Genomic DNA Translation: EAW73396.1
CCDSiCCDS14071.1
RefSeqiNP_060750.1, NM_018280.2
UniGeneiHs.567529

3D structure databases

ProteinModelPortaliQ9NV39
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9NV39, 13 interactors
STRINGi9606.ENSP00000327764

Polymorphism and mutation databases

BioMutaiC22orf26

Proteomic databases

PaxDbiQ9NV39
PRIDEiQ9NV39
ProteomicsDBi82744

Protocols and materials databases

DNASUi55267
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000396008; ENSP00000379329; ENSG00000182257
GeneIDi55267
KEGGihsa:55267
UCSCiuc003bgq.2 human

Organism-specific databases

CTDi55267
DisGeNETi55267
EuPathDBiHostDB:ENSG00000182257.6
GeneCardsiPRR34
HGNCiHGNC:25606 PRR34
neXtProtiNX_Q9NV39
OpenTargetsiENSG00000182257
PharmGKBiPA145149369
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410KHG1 Eukaryota
ENOG4110RAD LUCA
GeneTreeiENSGT00410000029629
HOGENOMiHOG000038015
HOVERGENiHBG081381
InParanoidiQ9NV39
OMAiLTFWAPG
OrthoDBiEOG091G15WS
PhylomeDBiQ9NV39
TreeFamiTF341481

Miscellaneous databases

GenomeRNAii55267
PROiPR:Q9NV39

Gene expression databases

BgeeiENSG00000182257 Expressed in 84 organ(s), highest expression level in uterus
CleanExiHS_C22orf26
ExpressionAtlasiQ9NV39 baseline and differential
GenevisibleiQ9NV39 HS

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiPRR34_HUMAN
AccessioniPrimary (citable) accession number: Q9NV39
Secondary accession number(s): B0QZ24
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 1, 2000
Last modified: September 12, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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Main funding by: National Institutes of Health

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