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UniProtKB - Q9NV31 (IMP3_HUMAN)

Entry version 170 (02 Dec 2020)
Sequence version 1 (01 Oct 2000)
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Protein

U3 small nucleolar ribonucleoprotein protein IMP3

Gene

IMP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, RNA-binding, rRNA-binding
Biological processRibosome biogenesis, rRNA processing

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9NV31

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-6790901, rRNA modification in the nucleus and cytosol
R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q9NV31

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
U3 small nucleolar ribonucleoprotein protein IMP3
Short name:
U3 snoRNP protein IMP3
Alternative name(s):
BRMS2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IMP3
Synonyms:C15orf12, MRPS4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000177971.8

Human Gene Nomenclature Database

More...HGNCi		HGNC:14497, IMP3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		612980, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NV31

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		55272

Open Targets

More...OpenTargetsi		ENSG00000177971

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA25517

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9NV31, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		IMP3

Domain mapping of disease mutations (DMDM)

More...DMDMi		52783099

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001327091 – 184U3 small nucleolar ribonucleoprotein protein IMP3Add BLAST184

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9NV31

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9NV31

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9NV31

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9NV31

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NV31

PeptideAtlas

More...PeptideAtlasi		Q9NV31

PRoteomics IDEntifications database

More...PRIDEi		Q9NV31

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		82742

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NV31

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NV31

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9NV31

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000177971, Expressed in prostate gland and 237 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NV31, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000177971, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10.

Interacts with MPHOSPH10.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120560, 60 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9NV31

Protein interaction database and analysis system

More...IntActi		Q9NV31, 30 interactors

Molecular INTeraction database

More...MINTi		Q9NV31

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000326981

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9NV31, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1184
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9NV31

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q9NV31

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini109 – 175S4 RNA-bindingPROSITE-ProRule annotationAdd BLAST67

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi32 – 74Arg-richAdd BLAST43

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS4 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4655, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00550000075090

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_097281_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NV31

Identification of Orthologs from Complete Genome Data

More...OMAi		TRHMEDF

Database of Orthologous Groups

More...OrthoDBi		1336285at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NV31

TreeFam database of animal gene trees

More...TreeFami		TF300149

Family and domain databases

Conserved Domains Database

More...CDDi		cd00165, S4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.290.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR022801, Ribosomal_S4/S9
IPR001912, Ribosomal_S4/S9_N
IPR002942, S4_RNA-bd
IPR036986, S4_RNA-bd_sf

The PANTHER Classification System

More...PANTHERi		PTHR11831, PTHR11831, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00163, Ribosomal_S4, 1 hit
PF01479, S4, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01390, Ribosomal_S4, 1 hit
SM00363, S4, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50889, S4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9NV31-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVRKLKFHEQ KLLKQVDFLN WEVTDHNLHE LRVLRRYRLQ RREDYTRYNQ 
        60         70         80         90        100
LSRAVRELAR RLRDLPERDQ FRVRASAALL DKLYALGLVP TRGSLELCDF 
       110        120        130        140        150
VTASSFCRRR LPTVLLKLRM AQHLQAAVAF VEQGHVRVGP DVVTDPAFLV 
       160        170        180 
TRSMEDFVTW VDSSKIKRHV LEYNEERDDF DLEA
Length:184
Mass (Da):21,850
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAAE0352DF7C790F1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti15Q → R in BAD96841 (Ref. 4) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY050497 mRNA Translation: AAL06639.1
AL136913 mRNA Translation: CAB66847.1
AK001830 mRNA Translation: BAA91929.1
AK057531 mRNA Translation: BAG51929.1
AK223121 mRNA Translation: BAD96841.1
CH471136 Genomic DNA Translation: EAW99244.1
BC006487 mRNA Translation: AAH06487.1
BC011745 mRNA Translation: AAH11745.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS10282.1

NCBI Reference Sequences

More...RefSeqi		NP_060755.1, NM_018285.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000314852; ENSP00000326981; ENSG00000177971
ENST00000403490; ENSP00000385217; ENSG00000177971

Database of genes from NCBI RefSeq genomes

More...GeneIDi		55272

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:55272

UCSC genome browser

More...UCSCi		uc002bat.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY050497 mRNA Translation: AAL06639.1
AL136913 mRNA Translation: CAB66847.1
AK001830 mRNA Translation: BAA91929.1
AK057531 mRNA Translation: BAG51929.1
AK223121 mRNA Translation: BAD96841.1
CH471136 Genomic DNA Translation: EAW99244.1
BC006487 mRNA Translation: AAH06487.1
BC011745 mRNA Translation: AAH11745.1
CCDSiCCDS10282.1
RefSeqiNP_060755.1, NM_018285.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CQJNMR-A109-166[»]
SMRiQ9NV31
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi120560, 60 interactors
CORUMiQ9NV31
IntActiQ9NV31, 30 interactors
MINTiQ9NV31
STRINGi9606.ENSP00000326981

PTM databases

iPTMnetiQ9NV31
PhosphoSitePlusiQ9NV31
SwissPalmiQ9NV31

Polymorphism and mutation databases

BioMutaiIMP3
DMDMi52783099

Proteomic databases

EPDiQ9NV31
jPOSTiQ9NV31
MassIVEiQ9NV31
MaxQBiQ9NV31
PaxDbiQ9NV31
PeptideAtlasiQ9NV31
PRIDEiQ9NV31
ProteomicsDBi82742

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		43256, 219 antibodies

The DNASU plasmid repository

More...DNASUi		55272

Genome annotation databases

EnsembliENST00000314852; ENSP00000326981; ENSG00000177971
ENST00000403490; ENSP00000385217; ENSG00000177971
GeneIDi55272
KEGGihsa:55272
UCSCiuc002bat.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55272
DisGeNETi55272
EuPathDBiHostDB:ENSG00000177971.8

GeneCards: human genes, protein and diseases

More...GeneCardsi		IMP3
HGNCiHGNC:14497, IMP3
HPAiENSG00000177971, Low tissue specificity
MIMi612980, gene
neXtProtiNX_Q9NV31
OpenTargetsiENSG00000177971
PharmGKBiPA25517

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4655, Eukaryota
GeneTreeiENSGT00550000075090
HOGENOMiCLU_097281_0_0_1
InParanoidiQ9NV31
OMAiTRHMEDF
OrthoDBi1336285at2759
PhylomeDBiQ9NV31
TreeFamiTF300149

Enzyme and pathway databases

PathwayCommonsiQ9NV31
ReactomeiR-HSA-6790901, rRNA modification in the nucleus and cytosol
R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
SIGNORiQ9NV31

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		55272, 743 hits in 850 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		IMP3, human
EvolutionaryTraceiQ9NV31

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		IMP3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		55272
PharosiQ9NV31, Tbio

Protein Ontology

More...PROi		PR:Q9NV31
RNActiQ9NV31, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000177971, Expressed in prostate gland and 237 other tissues
GenevisibleiQ9NV31, HS

Family and domain databases

CDDicd00165, S4, 1 hit
Gene3Di3.10.290.10, 1 hit
InterProiView protein in InterPro
IPR022801, Ribosomal_S4/S9
IPR001912, Ribosomal_S4/S9_N
IPR002942, S4_RNA-bd
IPR036986, S4_RNA-bd_sf
PANTHERiPTHR11831, PTHR11831, 1 hit
PfamiView protein in Pfam
PF00163, Ribosomal_S4, 1 hit
PF01479, S4, 1 hit
SMARTiView protein in SMART
SM01390, Ribosomal_S4, 1 hit
SM00363, S4, 1 hit
PROSITEiView protein in PROSITE
PS50889, S4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIMP3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NV31
Secondary accession number(s): B3KQ67, Q53G10
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: October 1, 2000
Last modified: December 2, 2020
This is version 170 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  5. Ribosomal proteins
    Ribosomal proteins families and list of entries
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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