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Entry version 158 (12 Aug 2020)
Sequence version 2 (05 Sep 2006)
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Protein

ATP-binding cassette sub-family F member 3

Gene

ABCF3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.By similarity

Caution

Lacks transmembrane domains and is probably not involved in transport.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi210 – 217ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi525 – 532ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiviral defense
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NUQ8

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.1.121.9, the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ATP-binding cassette sub-family F member 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCF3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000161204.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:72, ABCF3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NUQ8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55324

Open Targets

More...
OpenTargetsi
ENSG00000161204

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24407

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NUQ8, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ABCF3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
114149223

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002480422 – 709ATP-binding cassette sub-family F member 3Add BLAST708

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1
Modified residuei83PhosphoserineCombined sources1
Modified residuei155PhosphoserineCombined sources1
Modified residuei157PhosphoserineCombined sources1
Modified residuei161PhosphoserineCombined sources1
Modified residuei283PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NUQ8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NUQ8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NUQ8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NUQ8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NUQ8

PeptideAtlas

More...
PeptideAtlasi
Q9NUQ8

PRoteomics IDEntifications database

More...
PRIDEi
Q9NUQ8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
82712 [Q9NUQ8-1]
82713 [Q9NUQ8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NUQ8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NUQ8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000161204, Expressed in right adrenal gland and 213 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NUQ8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NUQ8, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000161204, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120605, 43 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NUQ8, 21 interactors

Molecular INTeraction database

More...
MINTi
Q9NUQ8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000411471

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NUQ8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NUQ8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini178 – 424ABC transporter 1PROSITE-ProRule annotationAdd BLAST247
Domaini492 – 707ABC transporter 2PROSITE-ProRule annotationAdd BLAST216

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0062, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155604

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000604_36_6_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NUQ8

KEGG Orthology (KO)

More...
KOi
K06158

Identification of Orthologs from Complete Genome Data

More...
OMAi
GNYTFWY

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NUQ8

TreeFam database of animal gene trees

More...
TreeFami
TF105209

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR032781, ABC_tran_Xtn
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00005, ABC_tran, 2 hits
PF12848, ABC_tran_Xtn, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00211, ABC_TRANSPORTER_1, 2 hits
PS50893, ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NUQ8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MATCAEILRS EFPEIDGQVF DYVTGVLHSG SADFESVDDL VEAVGELLQE
60 70 80 90 100
VSGDSKDDAG IRAVCQRMYN TLRLAEPQSQ GNSQVLLDAP IQLSKITENY
110 120 130 140 150
DCGTKLPGLL KREQSSTVNA KKLEKAEARL KAKQEKRSEK DTLKTSNPLV
160 170 180 190 200
LEEASASQAG SRKESRLESS GKNKSYDVRI ENFDVSFGDR VLLAGADVNL
210 220 230 240 250
AWGRRYGLVG RNGLGKTTLL KMLATRSLRV PAHISLLHVE QEVAGDDTPA
260 270 280 290 300
LQSVLESDSV REDLLRRERE LTAQIAAGRA EGSEAAELAE IYAKLEEIEA
310 320 330 340 350
DKAPARASVI LAGLGFTPKM QQQPTREFSG GWRMRLALAR ALFARPDLLL
360 370 380 390 400
LDEPTNMLDV RAILWLENYL QTWPSTILVV SHDRNFLNAI ATDIIHLHSQ
410 420 430 440 450
RLDGYRGDFE TFIKSKQERL LNQQREYEAQ QQYRQHIQVF IDRFRYNANR
460 470 480 490 500
ASQVQSKLKM LEKLPELKPV DKESEVVMKF PDGFEKFSPP ILQLDEVDFY
510 520 530 540 550
YDPKHVIFSR LSVSADLESR ICVVGENGAG KSTMLKLLLG DLAPVRGIRH
560 570 580 590 600
AHRNLKIGYF SQHHVEQLDL NVSAVELLAR KFPGRPEEEY RHQLGRYGIS
610 620 630 640 650
GELAMRPLAS LSGGQKSRVA FAQMTMPCPN FYILDEPTNH LDMETIEALG
660 670 680 690 700
RALNNFRGGV ILVSHDERFI RLVCRELWVC EGGGVTRVEG GFDQYRALLQ

EQFRREGFL
Length:709
Mass (Da):79,745
Last modified:September 5, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE7E0FDB6426F3F60
GO
Isoform 2 (identifier: Q9NUQ8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     69-74: Missing.

Show »
Length:703
Mass (Da):78,984
Checksum:iF952B10FD525CEB7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WCU6F8WCU6_HUMAN
ATP-binding cassette sub-family F m...
ABCF3
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB14989 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti231P → S in BAC03881 (PubMed:14702039).Curated1
Sequence conflicti289A → G in BAB14989 (PubMed:14702039).Curated1
Sequence conflicti468K → R in BAA92063 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027247503P → L1 PublicationCorresponds to variant dbSNP:rs11706273Ensembl.1
Natural variantiVAR_027248510R → H. Corresponds to variant dbSNP:rs9811715Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02014269 – 74Missing in isoform 2. 1 Publication6

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK002060 mRNA Translation: BAA92063.1
AK024758 mRNA Translation: BAB14989.1 Different initiation.
AK092415 mRNA Translation: BAC03881.1
AK290106 mRNA Translation: BAF82795.1
BC009253 mRNA Translation: AAH09253.1
BC051754 mRNA Translation: AAH51754.1
BC051884 mRNA Translation: AAH51884.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3254.1 [Q9NUQ8-1]
CCDS87173.1 [Q9NUQ8-2]

NCBI Reference Sequences

More...
RefSeqi
NP_060828.2, NM_018358.2 [Q9NUQ8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000292808; ENSP00000292808; ENSG00000161204 [Q9NUQ8-2]
ENST00000429586; ENSP00000411471; ENSG00000161204 [Q9NUQ8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55324

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55324

UCSC genome browser

More...
UCSCi
uc003fmz.3, human [Q9NUQ8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002060 mRNA Translation: BAA92063.1
AK024758 mRNA Translation: BAB14989.1 Different initiation.
AK092415 mRNA Translation: BAC03881.1
AK290106 mRNA Translation: BAF82795.1
BC009253 mRNA Translation: AAH09253.1
BC051754 mRNA Translation: AAH51754.1
BC051884 mRNA Translation: AAH51884.2
CCDSiCCDS3254.1 [Q9NUQ8-1]
CCDS87173.1 [Q9NUQ8-2]
RefSeqiNP_060828.2, NM_018358.2 [Q9NUQ8-1]

3D structure databases

SMRiQ9NUQ8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120605, 43 interactors
IntActiQ9NUQ8, 21 interactors
MINTiQ9NUQ8
STRINGi9606.ENSP00000411471

Protein family/group databases

TCDBi3.A.1.121.9, the atp-binding cassette (abc) superfamily

PTM databases

iPTMnetiQ9NUQ8
PhosphoSitePlusiQ9NUQ8

Polymorphism and mutation databases

BioMutaiABCF3
DMDMi114149223

Proteomic databases

EPDiQ9NUQ8
jPOSTiQ9NUQ8
MassIVEiQ9NUQ8
MaxQBiQ9NUQ8
PaxDbiQ9NUQ8
PeptideAtlasiQ9NUQ8
PRIDEiQ9NUQ8
ProteomicsDBi82712 [Q9NUQ8-1]
82713 [Q9NUQ8-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33796, 183 antibodies

The DNASU plasmid repository

More...
DNASUi
55324

Genome annotation databases

EnsembliENST00000292808; ENSP00000292808; ENSG00000161204 [Q9NUQ8-2]
ENST00000429586; ENSP00000411471; ENSG00000161204 [Q9NUQ8-1]
GeneIDi55324
KEGGihsa:55324
UCSCiuc003fmz.3, human [Q9NUQ8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55324
DisGeNETi55324
EuPathDBiHostDB:ENSG00000161204.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ABCF3
HGNCiHGNC:72, ABCF3
HPAiENSG00000161204, Low tissue specificity
neXtProtiNX_Q9NUQ8
OpenTargetsiENSG00000161204
PharmGKBiPA24407

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG0062, Eukaryota
GeneTreeiENSGT00940000155604
HOGENOMiCLU_000604_36_6_1
InParanoidiQ9NUQ8
KOiK06158
OMAiGNYTFWY
PhylomeDBiQ9NUQ8
TreeFamiTF105209

Enzyme and pathway databases

PathwayCommonsiQ9NUQ8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
55324, 4 hits in 870 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ABCF3, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55324
PharosiQ9NUQ8, Tdark

Protein Ontology

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PROi
PR:Q9NUQ8
RNActiQ9NUQ8, protein

Gene expression databases

BgeeiENSG00000161204, Expressed in right adrenal gland and 213 other tissues
ExpressionAtlasiQ9NUQ8, baseline and differential
GenevisibleiQ9NUQ8, HS

Family and domain databases

InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR032781, ABC_tran_Xtn
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00005, ABC_tran, 2 hits
PF12848, ABC_tran_Xtn, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SUPFAMiSSF52540, SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211, ABC_TRANSPORTER_1, 2 hits
PS50893, ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiABCF3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NUQ8
Secondary accession number(s): A8K241
, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: August 12, 2020
This is version 158 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
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