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UniProtKB - Q9NUM3 (S39A9_HUMAN)

Entry version 134 (07 Apr 2021)
Sequence version 2 (21 Aug 2007)
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Protein

Zinc transporter ZIP9

Gene

SLC39A9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a zinc-influx transporter.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Transport, Zinc transport
LigandZinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9NUM3

Protein family/group databases

Transport Classification Database

More...TCDBi		2.A.5.6.1, the zinc (zn(2+))-iron (fe(2+)) permease (zip) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc transporter ZIP9
Alternative name(s):
Solute carrier family 39 member 9
Zrt- and Irt-like protein 9
Short name:
ZIP-9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC39A9
Synonyms:ZIP9
ORF Names:UNQ714/PRO1377
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:20182, SLC39A9

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		619116, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NUM3

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000029364.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Transmembranei106 – 126HelicalSequence analysisAdd BLAST21
Transmembranei146 – 166HelicalSequence analysisAdd BLAST21
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Transmembranei210 – 230HelicalSequence analysisAdd BLAST21
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		55334

Open Targets

More...OpenTargetsi		ENSG00000029364

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134889179

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9NUM3, Tbio

Chemistry databases

Drug and drug target database

More...DrugBanki		DB14533, Zinc chloride
DB14548, Zinc sulfate, unspecified form

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SLC39A9

Domain mapping of disease mutations (DMDM)

More...DMDMi		156633628

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002975971 – 307Zinc transporter ZIP9Add BLAST307

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi29N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi241N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9NUM3

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9NUM3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9NUM3

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9NUM3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NUM3

PeptideAtlas

More...PeptideAtlasi		Q9NUM3

PRoteomics IDEntifications database

More...PRIDEi		Q9NUM3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		33545
82693 [Q9NUM3-1]
82694 [Q9NUM3-2]

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q9NUM3-2 [Q9NUM3-2]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9NUM3, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NUM3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NUM3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000029364, Expressed in testis and 221 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9NUM3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NUM3, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000029364, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
Q9NUM3
With#Exp.IntAct
ANKRD46 - isoform 1 [Q86W74-2]3EBI-2823239,EBI-12109402
APH1A [Q96BI3]3EBI-2823239,EBI-2606935
AQP6 [Q13520]3EBI-2823239,EBI-13059134
BNIP2 [Q12982]3EBI-2823239,EBI-752094
CBARP - isoform 2 [Q8N350-4]3EBI-2823239,EBI-19051169
CD79A [P11912]3EBI-2823239,EBI-7797864
CERS3 [Q8IU89]3EBI-2823239,EBI-18202821
CPLX4 [Q7Z7G2]3EBI-2823239,EBI-18013275
CRB3 - isoform 2 [Q9BUF7-2]3EBI-2823239,EBI-17233035
CREB3L1 [Q96BA8]3EBI-2823239,EBI-6942903
CREB3L3 [Q68CJ9]3EBI-2823239,EBI-852194
CYB5B [O43169]3EBI-2823239,EBI-1058710
ELOVL5 [Q9NYP7]3EBI-2823239,EBI-11037623
EVI2B - isoform 2 [P34910-2]3EBI-2823239,EBI-17640610
FFAR2 [O15552]3EBI-2823239,EBI-2833872
GJA8 [P48165]3EBI-2823239,EBI-17458373
GPR101 [Q96P66]3EBI-2823239,EBI-17935713
HERPUD2 [Q9BSE4]3EBI-2823239,EBI-2868124
HTR2C [P28335]3EBI-2823239,EBI-994141
LNPEP - isoform 2 [Q9UIQ6-2]3EBI-2823239,EBI-12133176
MANBAL [Q9NQG1]3EBI-2823239,EBI-3867271
MFSD14B [Q5SR56]3EBI-2823239,EBI-373355
MFSD5 [Q6N075]3EBI-2823239,EBI-3920969
MGST3 [O14880]3EBI-2823239,EBI-724754
NEU1 [Q99519]3EBI-2823239,EBI-721517
RTP2 [Q5QGT7]3EBI-2823239,EBI-10244780
SLC10A6 [Q3KNW5]3EBI-2823239,EBI-18159983
SLC39A2 [Q9NP94]3EBI-2823239,EBI-12898013
SLC66A1 - isoform 3 [Q6ZP29-3]3EBI-2823239,EBI-12889586
SLC7A1 [P30825]3EBI-2823239,EBI-4289564
SSMEM1 [Q8WWF3]3EBI-2823239,EBI-17280858
TM4SF18 [Q96CE8]3EBI-2823239,EBI-13351685
TMEM140 [Q9NV12]3EBI-2823239,EBI-2844246
TMEM237 - isoform 2 [Q96Q45-2]3EBI-2823239,EBI-10982110
TMEM86B [Q8N661]3EBI-2823239,EBI-2548832
TRHR [P34981]3EBI-2823239,EBI-18055230
VMP1 [Q96GC9]3EBI-2823239,EBI-2800296

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120615, 135 interactors

Protein interaction database and analysis system

More...IntActi		Q9NUM3, 82 interactors

Molecular INTeraction database

More...MINTi		Q9NUM3

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000336887

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9NUM3, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ZIP transporter (TC 2.A.5) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3907, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000010094

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NUM3

Identification of Orthologs from Complete Genome Data

More...OMAi		AAIMIHK

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NUM3

TreeFam database of animal gene trees

More...TreeFami		TF315051

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003689, ZIP

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02535, Zip, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NUM3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDDFISISLL SLAMLVGCYV AGIIPLAVNF SEERLKLVTV LGAGLLCGTA 
        60         70         80         90        100
LAVIVPEGVH ALYEDILEGK HHQASETHNV IASDKAAEKS VVHEHEHSHD 
       110        120        130        140        150
HTQLHAYIGV SLVLGFVFML LVDQIGNSHV HSTDDPEAAR SSNSKITTTL 
       160        170        180        190        200
GLVVHAAADG VALGAAASTS QTSVQLIVFV AIMLHKAPAA FGLVSFLMHA 
       210        220        230        240        250
GLERNRIRKH LLVFALAAPV MSMVTYLGLS KSSKEALSEV NATGVAMLFS 
       260        270        280        290        300
AGTFLYVATV HVLPEVGGIG HSHKPDATGG RGLSRLEVAA LVLGCLIPLI 

LSVGHQH
Length:307
Mass (Da):32,251
Last modified:August 21, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3F2CB0ED7B193183
GO
Isoform 2 (identifier: Q9NUM3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     135-157: Missing.

Show »
Length:284
Mass (Da):29,931
Checksum:i7A73F28242B69CF3
GO
Isoform 3 (identifier: Q9NUM3-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     232-232: S → D
     233-307: Missing.

Show »
Length:232
Mass (Da):24,626
Checksum:iB3A9CE397D40D590
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QX28M0QX28_HUMAN
Zinc transporter ZIP9
SLC39A9
241Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0D9SFA2A0A0D9SFA2_HUMAN
Zinc transporter ZIP9
SLC39A9
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti122V → M in BAD96267 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03464864E → D. Corresponds to variant dbSNP:rs2296723Ensembl.1
Natural variantiVAR_034649221M → T1 PublicationCorresponds to variant dbSNP:rs2232059Ensembl.1
Natural variantiVAR_034650285R → C1 PublicationCorresponds to variant dbSNP:rs17855898Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_027302135 – 157Missing in isoform 2. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_054057232S → D in isoform 3. 1 Publication1
Alternative sequenceiVSP_054058233 – 307Missing in isoform 3. 1 PublicationAdd BLAST75

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY358687 mRNA Translation: AAQ89050.1
AK002136 mRNA Translation: BAA92100.1
AK222547 mRNA Translation: BAD96267.1
AY780789 mRNA Translation: AAV98359.1
AL157996 Genomic DNA No translation available.
BC047682 mRNA Translation: AAH47682.1
BC064383 mRNA Translation: AAH64383.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS58327.1 [Q9NUM3-3]
CCDS58328.1 [Q9NUM3-2]
CCDS9795.1 [Q9NUM3-1]

NCBI Reference Sequences

More...RefSeqi		NP_001239077.1, NM_001252148.1 [Q9NUM3-2]
NP_001239079.1, NM_001252150.1 [Q9NUM3-3]
NP_001239080.1, NM_001252151.1
NP_001239081.1, NM_001252152.1
NP_060845.2, NM_018375.4 [Q9NUM3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000336643; ENSP00000336887; ENSG00000029364 [Q9NUM3-1]
ENST00000555840; ENSP00000450639; ENSG00000029364 [Q9NUM3-1]
ENST00000556605; ENSP00000452385; ENSG00000029364 [Q9NUM3-3]
ENST00000557046; ENSP00000451833; ENSG00000029364 [Q9NUM3-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		55334

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:55334

UCSC genome browser

More...UCSCi		uc001xle.5, human [Q9NUM3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358687 mRNA Translation: AAQ89050.1
AK002136 mRNA Translation: BAA92100.1
AK222547 mRNA Translation: BAD96267.1
AY780789 mRNA Translation: AAV98359.1
AL157996 Genomic DNA No translation available.
BC047682 mRNA Translation: AAH47682.1
BC064383 mRNA Translation: AAH64383.1
CCDSiCCDS58327.1 [Q9NUM3-3]
CCDS58328.1 [Q9NUM3-2]
CCDS9795.1 [Q9NUM3-1]
RefSeqiNP_001239077.1, NM_001252148.1 [Q9NUM3-2]
NP_001239079.1, NM_001252150.1 [Q9NUM3-3]
NP_001239080.1, NM_001252151.1
NP_001239081.1, NM_001252152.1
NP_060845.2, NM_018375.4 [Q9NUM3-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120615, 135 interactors
IntActiQ9NUM3, 82 interactors
MINTiQ9NUM3
STRINGi9606.ENSP00000336887

Chemistry databases

DrugBankiDB14533, Zinc chloride
DB14548, Zinc sulfate, unspecified form

Protein family/group databases

TCDBi2.A.5.6.1, the zinc (zn(2+))-iron (fe(2+)) permease (zip) family

PTM databases

GlyGeniQ9NUM3, 2 sites
iPTMnetiQ9NUM3
PhosphoSitePlusiQ9NUM3

Genetic variation databases

BioMutaiSLC39A9
DMDMi156633628

Proteomic databases

EPDiQ9NUM3
jPOSTiQ9NUM3
MassIVEiQ9NUM3
MaxQBiQ9NUM3
PaxDbiQ9NUM3
PeptideAtlasiQ9NUM3
PRIDEiQ9NUM3
ProteomicsDBi33545
82693 [Q9NUM3-1]
82694 [Q9NUM3-2]
TopDownProteomicsiQ9NUM3-2 [Q9NUM3-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		107, 129 antibodies

The DNASU plasmid repository

More...DNASUi		55334

Genome annotation databases

EnsembliENST00000336643; ENSP00000336887; ENSG00000029364 [Q9NUM3-1]
ENST00000555840; ENSP00000450639; ENSG00000029364 [Q9NUM3-1]
ENST00000556605; ENSP00000452385; ENSG00000029364 [Q9NUM3-3]
ENST00000557046; ENSP00000451833; ENSG00000029364 [Q9NUM3-2]
GeneIDi55334
KEGGihsa:55334
UCSCiuc001xle.5, human [Q9NUM3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55334
DisGeNETi55334

GeneCards: human genes, protein and diseases

More...GeneCardsi		SLC39A9
HGNCiHGNC:20182, SLC39A9
HPAiENSG00000029364, Low tissue specificity
MIMi619116, gene
neXtProtiNX_Q9NUM3
OpenTargetsiENSG00000029364
PharmGKBiPA134889179
VEuPathDBiHostDB:ENSG00000029364.11

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3907, Eukaryota
GeneTreeiENSGT00390000010094
InParanoidiQ9NUM3
OMAiAAIMIHK
PhylomeDBiQ9NUM3
TreeFamiTF315051

Enzyme and pathway databases

PathwayCommonsiQ9NUM3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		55334, 40 hits in 998 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SLC39A9, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		55334
PharosiQ9NUM3, Tbio

Protein Ontology

More...PROi		PR:Q9NUM3
RNActiQ9NUM3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000029364, Expressed in testis and 221 other tissues
ExpressionAtlasiQ9NUM3, baseline and differential
GenevisibleiQ9NUM3, HS

Family and domain databases

InterProiView protein in InterPro
IPR003689, ZIP
PfamiView protein in Pfam
PF02535, Zip, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS39A9_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NUM3
Secondary accession number(s): G3V5J8
, Q53HN3, Q5MJQ0, Q6P2Q1, Q86WY2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: August 21, 2007
Last modified: April 7, 2021
This is version 134 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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