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Entry version 139 (12 Aug 2020)
Sequence version 3 (20 Jun 2003)
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Protein

Cerebral cavernous malformations 2 protein-like

Gene

CCM2L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NUG4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cerebral cavernous malformations 2 protein-like
Short name:
CCM2-like
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCM2L
Synonyms:C20orf160
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000101331.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:16153, CCM2L

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NUG4

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000101331

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25702

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NUG4, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCM2L

Domain mapping of disease mutations (DMDM)

More...
DMDMi
32171369

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000794761 – 571Cerebral cavernous malformations 2 protein-likeAdd BLAST571

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NUG4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NUG4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NUG4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NUG4

PeptideAtlas

More...
PeptideAtlasi
Q9NUG4

PRoteomics IDEntifications database

More...
PRIDEi
Q9NUG4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
82668 [Q9NUG4-1]
82669 [Q9NUG4-2]
82670 [Q9NUG4-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NUG4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NUG4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000101331, Expressed in spleen and 177 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NUG4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NUG4, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000101331, Tissue enhanced (lymphoid)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
126664, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NUG4, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000262659

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NUG4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NUG4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi217 – 222Poly-Gly6
Compositional biasi252 – 261Poly-Gly10
Compositional biasi273 – 278Poly-Gly6
Compositional biasi547 – 554Poly-Asp8

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CCM2 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QW6F, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016168

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_051853_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NUG4

Identification of Orthologs from Complete Genome Data

More...
OMAi
CTMAPRT

Database of Orthologous Groups

More...
OrthoDBi
1446057at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NUG4

TreeFam database of animal gene trees

More...
TreeFami
TF328517

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13516, HHD_CCM2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032375, CCM2_C
IPR026159, Malcavernin
IPR011993, PH-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR21642, PTHR21642, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16545, CCM2_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9NUG4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEYEVKKGKK GFVSPIRRLV FPKAGRRAAC RSSVSRRPLH SMPLYPPDYL
60 70 80 90 100
IDPQILLCDY LEKEVKFLGH LTWVTSSLNP SSRDELLQLL DTARQLKELP
110 120 130 140 150
LKTTAEQDSI LSLSARCLLL TWRDNEELIL RIPTHEIAAA SYLQDDALHL
160 170 180 190 200
LVLKTGLGVD PVPAGVDASP GGAGRDPGPP GGAPEKRRVG TAERRHTICS
210 220 230 240 250
LDWRMGWGGG AAEARAGGGG GGSLERQRAG ARASGSWERR QTFSGSWERR
260 270 280 290 300
HGGGGGGGGA GKPGGSWERR QAGSGGGGSW ERRHPGPNPL DPQDPSPDAY
310 320 330 340 350
CNLVILAVAN RDAAEESCAL ICQVFQIIYG DQSIECVDRA GYHYTSTPER
360 370 380 390 400
PWLCSRSESC HTDGTYAYDA DFSCCSSFNG SQDTFEACYS GTSTPSFHGS
410 420 430 440 450
HCSGSDHSSL GLEQLQDYMV TLRSKLGPLE IQQFAMLLRE YRLGLPIQDY
460 470 480 490 500
CTGLLKLYGD RRKFLLLGMR PFIPDQDIGY FEGFLEGVGI REGGILTDSF
510 520 530 540 550
GRIKRSMSST SASAVRSYDG AAQRPEAQAF HRLLADITHD IEALAPDDDD
560 570
DDEDEPRGSR GGSDAAEDNY L
Length:571
Mass (Da):62,179
Last modified:June 20, 2003 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i369302A71BD00491
GO
Isoform 2 (identifier: Q9NUG4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     357-571: SESCHTDGTY...GSDAAEDNYL → IMAPRTPLKH...CPSRTIAQAC

Show »
Length:433
Mass (Da):46,728
Checksum:iC29411F6849B3BC8
GO
Isoform 3 (identifier: Q9NUG4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     215-235: RAGGGGGGSLERQRAGARASG → PTRSTRRTPAPTPTATWSSWL
     236-571: Missing.

Show »
Length:235
Mass (Da):25,908
Checksum:iA1F3EF1377553E8D
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH32455 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_007634215 – 235RAGGG…ARASG → PTRSTRRTPAPTPTATWSSW L in isoform 3. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_007635236 – 571Missing in isoform 3. 1 PublicationAdd BLAST336
Alternative sequenceiVSP_007633357 – 571SESCH…EDNYL → IMAPRTPLKHVTAARPHLLS MAPTAAAATTAVWAWSSYRI TWSRCGVSWGPSRSSSLRCC CGSTGWGCPSRTIAQAC in isoform 2. 1 PublicationAdd BLAST215

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK057090 mRNA Translation: BAB71363.1
AL031658 Genomic DNA No translation available.
BC030254 mRNA Translation: AAH30254.1
BC032455 mRNA Translation: AAH32455.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13195.1 [Q9NUG4-2]

NCBI Reference Sequences

More...
RefSeqi
NP_542192.2, NM_080625.3 [Q9NUG4-2]
XP_006723769.1, XM_006723706.3 [Q9NUG4-2]
XP_011526871.1, XM_011528569.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000262659; ENSP00000262659; ENSG00000101331 [Q9NUG4-2]
ENST00000452892; ENSP00000392448; ENSG00000101331 [Q9NUG4-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
140706

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:140706

UCSC genome browser

More...
UCSCi
uc002wxf.3, human [Q9NUG4-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057090 mRNA Translation: BAB71363.1
AL031658 Genomic DNA No translation available.
BC030254 mRNA Translation: AAH30254.1
BC032455 mRNA Translation: AAH32455.1 Different initiation.
CCDSiCCDS13195.1 [Q9NUG4-2]
RefSeqiNP_542192.2, NM_080625.3 [Q9NUG4-2]
XP_006723769.1, XM_006723706.3 [Q9NUG4-2]
XP_011526871.1, XM_011528569.1

3D structure databases

SMRiQ9NUG4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi126664, 2 interactors
IntActiQ9NUG4, 7 interactors
STRINGi9606.ENSP00000262659

PTM databases

iPTMnetiQ9NUG4
PhosphoSitePlusiQ9NUG4

Polymorphism and mutation databases

BioMutaiCCM2L
DMDMi32171369

Proteomic databases

EPDiQ9NUG4
jPOSTiQ9NUG4
MassIVEiQ9NUG4
PaxDbiQ9NUG4
PeptideAtlasiQ9NUG4
PRIDEiQ9NUG4
ProteomicsDBi82668 [Q9NUG4-1]
82669 [Q9NUG4-2]
82670 [Q9NUG4-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2011, 70 antibodies

Genome annotation databases

EnsembliENST00000262659; ENSP00000262659; ENSG00000101331 [Q9NUG4-2]
ENST00000452892; ENSP00000392448; ENSG00000101331 [Q9NUG4-1]
GeneIDi140706
KEGGihsa:140706
UCSCiuc002wxf.3, human [Q9NUG4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
140706
EuPathDBiHostDB:ENSG00000101331.15

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCM2L
HGNCiHGNC:16153, CCM2L
HPAiENSG00000101331, Tissue enhanced (lymphoid)
neXtProtiNX_Q9NUG4
OpenTargetsiENSG00000101331
PharmGKBiPA25702

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QW6F, Eukaryota
GeneTreeiENSGT00390000016168
HOGENOMiCLU_051853_0_0_1
InParanoidiQ9NUG4
OMAiCTMAPRT
OrthoDBi1446057at2759
PhylomeDBiQ9NUG4
TreeFamiTF328517

Enzyme and pathway databases

PathwayCommonsiQ9NUG4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
140706, 2 hits in 865 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CCM2L, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
140706
PharosiQ9NUG4, Tdark

Protein Ontology

More...
PROi
PR:Q9NUG4
RNActiQ9NUG4, protein

Gene expression databases

BgeeiENSG00000101331, Expressed in spleen and 177 other tissues
ExpressionAtlasiQ9NUG4, baseline and differential
GenevisibleiQ9NUG4, HS

Family and domain databases

CDDicd13516, HHD_CCM2, 1 hit
Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR032375, CCM2_C
IPR026159, Malcavernin
IPR011993, PH-like_dom_sf
PANTHERiPTHR21642, PTHR21642, 1 hit
PfamiView protein in Pfam
PF16545, CCM2_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCM2L_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NUG4
Secondary accession number(s): Q5JYR9
, Q8N5F1, Q8N6G8, Q96MD5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2003
Last sequence update: June 20, 2003
Last modified: August 12, 2020
This is version 139 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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