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Entry version 113 (18 Sep 2019)
Sequence version 2 (01 Jun 2001)
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Protein

Uncharacterized protein C20orf96

Gene

C20orf96

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C20orf96
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:16227 C20orf96

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NUD7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000196476

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25803

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C20orf96

Domain mapping of disease mutations (DMDM)

More...
DMDMi
26392576

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000794501 – 363Uncharacterized protein C20orf96Add BLAST363

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9NUD7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NUD7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NUD7

PeptideAtlas

More...
PeptideAtlasi
Q9NUD7

PRoteomics IDEntifications database

More...
PRIDEi
Q9NUD7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
82665

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NUD7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NUD7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000196476 Expressed in 94 organ(s), highest expression level in right uterine tube

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NUD7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NUD7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA048649

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126645, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NUD7, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000353470

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9NUD7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili109 – 329Sequence analysisAdd BLAST221

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi264 – 268Poly-Lys5

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIXG Eukaryota
ENOG4111YXE LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003339

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112025

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NUD7

Identification of Orthologs from Complete Genome Data

More...
OMAi
VPWQQSK

Database of Orthologous Groups

More...
OrthoDBi
1168106at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NUD7

TreeFam database of animal gene trees

More...
TreeFami
TF330721

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029236 DUF4618

The PANTHER Classification System

More...
PANTHERi
PTHR28574 PTHR28574, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15397 DUF4618, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9NUD7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHVLQKPKH SGTHSIVQEF QVPDYVPWQQ SKQETKPSTL PPVQQANSLH
60 70 80 90 100
TSKMKTLTRV QPVFHFKPTT VVTSCQPKNP RELHRRRKLD PGKMHAKIWL
110 120 130 140 150
MKTSLRSGRA ALRELRSREN FLSKLNRELI ETIQEMENST TLHVRALLQQ
160 170 180 190 200
QDTLATIIDI LEYSNKKRLQ QLKSELQEWE EKKKCKMSYL EQQAEQLNAK
210 220 230 240 250
IEKTQEEVNF LSTYMDHEYS IKSVQISTLM RQLQQVKDSQ QDELDDLGEM
260 270 280 290 300
RRKVLESLSD KIQKKKKKIL SSVVAETQRP YEEALLQKMW ESQDFLKCMQ
310 320 330 340 350
RFREIIDQFE ENMPVLRAEV EELQAQTREP REVIFEDVLL RRPKCTPDMD
360
VILNIPVEEP LPF
Length:363
Mass (Da):42,859
Last modified:June 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0B1A597E972A7EAD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5GZA9F5GZA9_HUMAN
Uncharacterized protein C20orf96
C20orf96
362Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5JYC3Q5JYC3_HUMAN
Uncharacterized protein C20orf96
C20orf96
328Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC03772 differs from that shown. Reason: Frameshift at position 304.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_056847305I → F3 PublicationsCorresponds to variant dbSNP:rs3827147Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK097394 mRNA Translation: BAC05033.1
AK091924 mRNA Translation: BAC03772.1 Frameshift.
AL034548 Genomic DNA No translation available.
CH471133 Genomic DNA Translation: EAX10681.1
BC134417 mRNA Translation: AAI34418.1
BC137450 mRNA Translation: AAI37451.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12994.1

NCBI Reference Sequences

More...
RefSeqi
NP_542138.1, NM_080571.1
NP_695001.2, NM_153269.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000360321; ENSP00000353470; ENSG00000196476

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
140680

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:140680

UCSC genome browser

More...
UCSCi
uc002wde.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097394 mRNA Translation: BAC05033.1
AK091924 mRNA Translation: BAC03772.1 Frameshift.
AL034548 Genomic DNA No translation available.
CH471133 Genomic DNA Translation: EAX10681.1
BC134417 mRNA Translation: AAI34418.1
BC137450 mRNA Translation: AAI37451.1
CCDSiCCDS12994.1
RefSeqiNP_542138.1, NM_080571.1
NP_695001.2, NM_153269.2

3D structure databases

SMRiQ9NUD7
ModBaseiSearch...

Protein-protein interaction databases

BioGridi126645, 4 interactors
IntActiQ9NUD7, 3 interactors
STRINGi9606.ENSP00000353470

PTM databases

iPTMnetiQ9NUD7
PhosphoSitePlusiQ9NUD7

Polymorphism and mutation databases

BioMutaiC20orf96
DMDMi26392576

Proteomic databases

EPDiQ9NUD7
MassIVEiQ9NUD7
PaxDbiQ9NUD7
PeptideAtlasiQ9NUD7
PRIDEiQ9NUD7
ProteomicsDBi82665

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000360321; ENSP00000353470; ENSG00000196476
GeneIDi140680
KEGGihsa:140680
UCSCiuc002wde.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
140680

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C20orf96
HGNCiHGNC:16227 C20orf96
HPAiHPA048649
neXtProtiNX_Q9NUD7
OpenTargetsiENSG00000196476
PharmGKBiPA25803

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIXG Eukaryota
ENOG4111YXE LUCA
GeneTreeiENSGT00390000003339
HOGENOMiHOG000112025
InParanoidiQ9NUD7
OMAiVPWQQSK
OrthoDBi1168106at2759
PhylomeDBiQ9NUD7
TreeFamiTF330721

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C20orf96 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
140680

Pharos

More...
Pharosi
Q9NUD7

Protein Ontology

More...
PROi
PR:Q9NUD7

Gene expression databases

BgeeiENSG00000196476 Expressed in 94 organ(s), highest expression level in right uterine tube
ExpressionAtlasiQ9NUD7 baseline and differential
GenevisibleiQ9NUD7 HS

Family and domain databases

InterProiView protein in InterPro
IPR029236 DUF4618
PANTHERiPTHR28574 PTHR28574, 1 hit
PfamiView protein in Pfam
PF15397 DUF4618, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCT096_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NUD7
Secondary accession number(s): A3KPE0
, B2RPH9, Q8N840, Q8NAX5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: June 1, 2001
Last modified: September 18, 2019
This is version 113 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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