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Entry version 143 (13 Nov 2019)
Sequence version 3 (02 Mar 2010)
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Protein

Teneurin-2

Gene

TENM2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Induces homophilic cell-cell adhesion (By similarity). May function as a cellular signal transducer.By similarity1 Publication
Isoform 2: Acts as a ligand of the ADGRL1 receptor. Mediates axon guidance and heterophilic cell-cell adhesion.1 Publication
Ten-2 intracellular domain: Induces gene transcription inhibition.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processCell adhesion, Transcription, Transcription regulation

Protein family/group databases

Transport Classification Database

More...
TCDBi
9.B.87.1.20 the selenoprotein p receptor (selp-receptor) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Teneurin-2
Short name:
Ten-2
Alternative name(s):
Protein Odd Oz/ten-m homolog 2
Tenascin-M2
Short name:
Ten-m2
Teneurin transmembrane protein 2
Cleaved into the following 2 chains:
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TENM2
Synonyms:KIAA1127, ODZ2, TNM2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29943 TENM2

Online Mendelian Inheritance in Man (OMIM)

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MIMi
610119 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NT68

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 379CytoplasmicSequence analysisAdd BLAST379
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei380 – 400HelicalSequence analysisAdd BLAST21
Topological domaini401 – 2774ExtracellularSequence analysisAdd BLAST2374

Keywords - Cellular componenti

Cell junction, Cell membrane, Cell projection, Endoplasmic reticulum, Golgi apparatus, Membrane, Nucleus, Postsynaptic cell membrane, Synapse, Synaptosome

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
57451

Open Targets

More...
OpenTargetsi
ENSG00000145934

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NT68

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TENM2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
290457667

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002595011 – 2774Teneurin-2Add BLAST2774
ChainiPRO_00004210111 – ?Ten-2 intracellular domainBy similarity
ChainiPRO_0000421012529 – 2774Ten-2, soluble formBy similarityAdd BLAST2246

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei90PhosphoserineBy similarity1
Modified residuei124PhosphoserineBy similarity1
Modified residuei155PhosphothreonineBy similarity1
Modified residuei157PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi443N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi482N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi576 ↔ 586PROSITE-ProRule annotation
Disulfide bondi580 ↔ 591PROSITE-ProRule annotation
Disulfide bondi593 ↔ 602PROSITE-ProRule annotation
Disulfide bondi611 ↔ 622PROSITE-ProRule annotation
Disulfide bondi624 ↔ 633PROSITE-ProRule annotation
Disulfide bondi640 ↔ 651PROSITE-ProRule annotation
Disulfide bondi645 ↔ 656PROSITE-ProRule annotation
Disulfide bondi658 ↔ 667PROSITE-ProRule annotation
Disulfide bondi672 ↔ 683PROSITE-ProRule annotation
Disulfide bondi677 ↔ 688PROSITE-ProRule annotation
Disulfide bondi690 ↔ 699PROSITE-ProRule annotation
Disulfide bondi710 ↔ 723PROSITE-ProRule annotation
Disulfide bondi725 ↔ 734PROSITE-ProRule annotation
Disulfide bondi739 ↔ 749PROSITE-ProRule annotation
Disulfide bondi743 ↔ 754PROSITE-ProRule annotation
Disulfide bondi756 ↔ 765PROSITE-ProRule annotation
Disulfide bondi770 ↔ 780PROSITE-ProRule annotation
Disulfide bondi774 ↔ 785PROSITE-ProRule annotation
Disulfide bondi787 ↔ 796PROSITE-ProRule annotation
Disulfide bondi810 ↔ 820PROSITE-ProRule annotation
Disulfide bondi814 ↔ 829PROSITE-ProRule annotation
Disulfide bondi831 ↔ 840PROSITE-ProRule annotation
Glycosylationi925N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi948N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1267N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1616N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1712N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1749N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1773N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1807N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1892N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1993N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2197N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2337N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2648N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Ten-2, soluble form: Derives from the membrane form by proteolytic processing.By similarity
Ten-2 intracellular domain: Derives from the plasma membrane form by proteolytic cleavage and translocates to the nucleus. Homophilic binding of the C-terminal extracellular domain stimulates its proteolytic cleavage and release in the cytoplasmic. Is subjected to rapid degradation by the proteasome pathway (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei528 – 529CleavageBy similarity2

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NT68

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NT68

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NT68

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NT68

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NT68

PeptideAtlas

More...
PeptideAtlasi
Q9NT68

PRoteomics IDEntifications database

More...
PRIDEi
Q9NT68

ProteomicsDB: a multi-organism proteome resource

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ProteomicsDBi
82603 [Q9NT68-1]

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1796

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NT68

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NT68

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in heart, followed by brain, liver, kidney and fetal brain and weakly expressed in lung and testis. No expression was detected in skeletal muscle, pancreas, spleen, ovary and fetal liver.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000145934 Expressed in 153 organ(s), highest expression level in left ventricle myocardium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NT68 baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA038018
HPA038420
HPA068691

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer; disulfide-linked (Probable). Heterodimer with either TENM1 or TENM3. May also form heterodimer with TENM4 (By similarity). Isoform 2 (C-terminal globular domain) interacts with ADGRL1 isoform 2.

By similarityCurated1 Publication

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9NT68, 6 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000429430

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

12774
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NT68

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 375Teneurin N-terminalPROSITE-ProRule annotationAdd BLAST375
Domaini575 – 603EGF-like 1PROSITE-ProRule annotationAdd BLAST29
Domaini598 – 634EGF-like 2PROSITE-ProRule annotationAdd BLAST37
Domaini636 – 668EGF-like 3PROSITE-ProRule annotationAdd BLAST33
Domaini669 – 701EGF-like 4PROSITE-ProRule annotationAdd BLAST33
Domaini702 – 735EGF-like 5PROSITE-ProRule annotationAdd BLAST34
Domaini738 – 766EGF-like 6PROSITE-ProRule annotationAdd BLAST29
Domaini769 – 797EGF-like 7PROSITE-ProRule annotationAdd BLAST29
Domaini808 – 841EGF-like 8PROSITE-ProRule annotationAdd BLAST34
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1272 – 1316NHL 1Add BLAST45
Repeati1342 – 1386NHL 2Add BLAST45
Repeati1401 – 1452NHL 3Add BLAST52
Repeati1474 – 1501NHL 4Add BLAST28
Repeati1530 – 1573NHL 5Add BLAST44
Repeati1583 – 1602YD 1Add BLAST20
Repeati1619 – 1639YD 2Add BLAST21
Repeati1682 – 1701YD 3Add BLAST20
Repeati1702 – 1724YD 4Add BLAST23
Repeati1895 – 1914YD 5Add BLAST20
Repeati1936 – 1954YD 6Add BLAST19
Repeati1955 – 1975YD 7Add BLAST21
Repeati1982 – 1999YD 8Add BLAST18
Repeati2000 – 2021YD 9Add BLAST22
Repeati2022 – 2039YD 10Add BLAST18
Repeati2042 – 2062YD 11Add BLAST21
Repeati2065 – 2085YD 12Add BLAST21
Repeati2093 – 2113YD 13Add BLAST21
Repeati2119 – 2136YD 14Add BLAST18
Repeati2137 – 2163YD 15Add BLAST27
Repeati2165 – 2178YD 16Add BLAST14
Repeati2179 – 2202YD 17Add BLAST24
Repeati2205 – 2225YD 18Add BLAST21
Repeati2226 – 2246YD 19Add BLAST21
Repeati2248 – 2268YD 20Add BLAST21
Repeati2280 – 2300YD 21Add BLAST21
Repeati2302 – 2322YD 22Add BLAST21
Repeati2348 – 2389YD 23Add BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi331 – 334Poly-Ser4

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

EGF-like domains 2 and 5 which have an odd number of cysteines might enable the formation of intermolecular disulfide bonds.
Cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteins.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tenascin family. Teneurin subfamily.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1225 Eukaryota
KOG4659 Eukaryota
ENOG410XQQD LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182725

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231701

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NT68

Identification of Orthologs from Complete Genome Data

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OMAi
NNNPAHK

Database of Orthologous Groups

More...
OrthoDBi
7516at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NT68

TreeFam database of animal gene trees

More...
TreeFami
TF316833

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.120.10.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR008969 CarboxyPept-like_regulatory
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR011044 Quino_amine_DH_bsu
IPR022385 Rhs_assc_core
IPR027689 Ten-2/3
IPR009471 Ten_N
IPR028916 Tox-GHH_dom
IPR006530 YD

The PANTHER Classification System

More...
PANTHERi
PTHR11219:SF8 PTHR11219:SF8, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06484 Ten_N, 1 hit
PF15636 Tox-GHH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181 EGF, 8 hits
SM00179 EGF_CA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49464 SSF49464, 1 hit
SSF50969 SSF50969, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03696 Rhs_assc_core, 1 hit
TIGR01643 YD_repeat_2x, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022 EGF_1, 8 hits
PS01186 EGF_2, 7 hits
PS50026 EGF_3, 5 hits
PS51361 TENEURIN_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NT68-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDVKDRRHRS LTRGRCGKEC RYTSSSLDSE DCRVPTQKSY SSSETLKAYD
60 70 80 90 100
HDSRMHYGNR VTDLIHRESD EFPRQGTNFT LAELGICEPS PHRSGYCSDM
110 120 130 140 150
GILHQGYSLS TGSDADSDTE GGMSPEHAIR LWGRGIKSRR SSGLSSRENS
160 170 180 190 200
ALTLTDSDNE NKSDDENGRP IPPTSSPSLL PSAQLPSSHN PPPVSCQMPL
210 220 230 240 250
LDSNTSHQIM DTNPDEEFSP NSYLLRACSG PQQASSSGPP NHHSQSTLRP
260 270 280 290 300
PLPPPHNHTL SHHHSSANSL NRNSLTNRRS QIHAPAPAPN DLATTPESVQ
310 320 330 340 350
LQDSWVLNSN VPLETRHFLF KTSSGSTPLF SSSSPGYPLT SGTVYTPPPR
360 370 380 390 400
LLPRNTFSRK AFKLKKPSKY CSWKCAALSA IAAALLLAIL LAYFIAMHLL
410 420 430 440 450
GLNWQLQPAD GHTFNNGIRT GLPGNDDVAT MPSGGKVPWS LKNSSIDSGE
460 470 480 490 500
AEVGRRVTQE VPPGVFWRSQ IHISQPQFLK FNISLGKDAL FGVYIRRGLP
510 520 530 540 550
PSHAQYDFME RLDGKEKWSV VESPRERRSI QTLVQNEAVF VQYLDVGLWH
560 570 580 590 600
LAFYNDGKDK EMVSFNTVVL DSVQDCPRNC HGNGECVSGV CHCFPGFLGA
610 620 630 640 650
DCAKAACPVL CSGNGQYSKG TCQCYSGWKG AECDVPMNQC IDPSCGGHGS
660 670 680 690 700
CIDGNCVCSA GYKGEHCEEV DCLDPTCSSH GVCVNGECLC SPGWGGLNCE
710 720 730 740 750
LARVQCPDQC SGHGTYLPDT GLCSCDPNWM GPDCSVEVCS VDCGTHGVCI
760 770 780 790 800
GGACRCEEGW TGAACDQRVC HPRCIEHGTC KDGKCECREG WNGEHCTIGR
810 820 830 840 850
QTAGTETDGC PDLCNGNGRC TLGQNSWQCV CQTGWRGPGC NVAMETSCAD
860 870 880 890 900
NKDNEGDGLV DCLDPDCCLQ SACQNSLLCR GSRDPLDIIQ QGQTDWPAVK
910 920 930 940 950
SFYDRIKLLA GKDSTHIIPG ENPFNSSLVS LIRGQVVTTD GTPLVGVNVS
960 970 980 990 1000
FVKYPKYGYT ITRQDGTFDL IANGGASLTL HFERAPFMSQ ERTVWLPWNS
1010 1020 1030 1040 1050
FYAMDTLVMK TEENSIPSCD LSGFVRPDPI IISSPLSTFF SAAPGQNPIV
1060 1070 1080 1090 1100
PETQVLHEEI ELPGSNVKLR YLSSRTAGYK SLLKITMTQS TVPLNLIRVH
1110 1120 1130 1140 1150
LMVAVEGHLF QKSFQASPNL AYTFIWDKTD AYGQRVYGLS DAVVSVGFEY
1160 1170 1180 1190 1200
ETCPSLILWE KRTALLQGFE LDPSNLGGWS LDKHHILNVK SGILHKGTGE
1210 1220 1230 1240 1250
NQFLTQQPAI ITSIMGNGRR RSISCPSCNG LAEGNKLLAP VALAVGIDGS
1260 1270 1280 1290 1300
LYVGDFNYIR RIFPSRNVTS ILELRNKEFK HSNNPAHKYY LAVDPVSGSL
1310 1320 1330 1340 1350
YVSDTNSRRI YRVKSLSGTK DLAGNSEVVA GTGEQCLPFD EARCGDGGKA
1360 1370 1380 1390 1400
IDATLMSPRG IAVDKNGLMY FVDATMIRKV DQNGIISTLL GSNDLTAVRP
1410 1420 1430 1440 1450
LSCDSSMDVA QVRLEWPTDL AVNPMDNSLY VLENNVILRI TENHQVSIIA
1460 1470 1480 1490 1500
GRPMHCQVPG IDYSLSKLAI HSALESASAI AISHTGVLYI TETDEKKINR
1510 1520 1530 1540 1550
LRQVTTNGEI CLLAGAASDC DCKNDVNCNC YSGDDAYATD AILNSPSSLA
1560 1570 1580 1590 1600
VAPDGTIYIA DLGNIRIRAV SKNKPVLNAF NQYEAASPGE QELYVFNADG
1610 1620 1630 1640 1650
IHQYTVSLVT GEYLYNFTYS TDNDVTELID NNGNSLKIRR DSSGMPRHLL
1660 1670 1680 1690 1700
MPDNQIITLT VGTNGGLKVV STQNLELGLM TYDGNTGLLA TKSDETGWTT
1710 1720 1730 1740 1750
FYDYDHEGRL TNVTRPTGVV TSLHREMEKS ITIDIENSNR DDDVTVITNL
1760 1770 1780 1790 1800
SSVEASYTVV QDQVRNSYQL CNNGTLRVMY ANGMGISFHS EPHVLAGTIT
1810 1820 1830 1840 1850
PTIGRCNISL PMENGLNSIE WRLRKEQIKG KVTIFGRKLR VHGRNLLSID
1860 1870 1880 1890 1900
YDRNIRTEKI YDDHRKFTLR IIYDQVGRPF LWLPSSGLAA VNVSYFFNGR
1910 1920 1930 1940 1950
LAGLQRGAMS ERTDIDKQGR IVSRMFADGK VWSYSYLDKS MVLLLQSQRQ
1960 1970 1980 1990 2000
YIFEYDSSDR LLAVTMPSVA RHSMSTHTSI GYIRNIYNPP ESNASVIFDY
2010 2020 2030 2040 2050
SDDGRILKTS FLGTGRQVFY KYGKLSKLSE IVYDSTAVTF GYDETTGVLK
2060 2070 2080 2090 2100
MVNLQSGGFS CTIRYRKIGP LVDKQIYRFS EEGMVNARFD YTYHDNSFRI
2110 2120 2130 2140 2150
ASIKPVISET PLPVDLYRYD EISGKVEHFG KFGVIYYDIN QIITTAVMTL
2160 2170 2180 2190 2200
SKHFDTHGRI KEVQYEMFRS LMYWMTVQYD SMGRVIKREL KLGPYANTTK
2210 2220 2230 2240 2250
YTYDYDGDGQ LQSVAVNDRP TWRYSYDLNG NLHLLNPGNS VRLMPLRYDL
2260 2270 2280 2290 2300
RDRITRLGDV QYKIDDDGYL CQRGSDIFEY NSKGLLTRAY NKASGWSVQY
2310 2320 2330 2340 2350
RYDGVGRRAS YKTNLGHHLQ YFYSDLHNPT RITHVYNHSN SEITSLYYDL
2360 2370 2380 2390 2400
QGHLFAMESS SGEEYYVASD NTGTPLAVFS INGLMIKQLQ YTAYGEIYYD
2410 2420 2430 2440 2450
SNPDFQMVIG FHGGLYDPLT KLVHFTQRDY DVLAGRWTSP DYTMWKNVGK
2460 2470 2480 2490 2500
EPAPFNLYMF KSNNPLSSEL DLKNYVTDVK SWLVMFGFQL SNIIPGFPRA
2510 2520 2530 2540 2550
KMYFVPPPYE LSESQASENG QLITGVQQTT ERHNQAFMAL EGQVITKKLH
2560 2570 2580 2590 2600
ASIREKAGHW FATTTPIIGK GIMFAIKEGR VTTGVSSIAS EDSRKVASVL
2610 2620 2630 2640 2650
NNAYYLDKMH YSIEGKDTHY FVKIGSADGD LVTLGTTIGR KVLESGVNVT
2660 2670 2680 2690 2700
VSQPTLLVNG RTRRFTNIEF QYSTLLLSIR YGLTPDTLDE EKARVLDQAR
2710 2720 2730 2740 2750
QRALGTAWAK EQQKARDGRE GSRLWTEGEK QQLLSTGRVQ GYEGYYVLPV
2760 2770
EQYPELADSS SNIQFLRQNE MGKR
Length:2,774
Mass (Da):307,787
Last modified:March 2, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC23DFD9BCD9D3F60
GO
Isoform 2 (identifier: Q9NT68-2) [UniParc]FASTAAdd to basket
Also known as: Lasso, LPH1-associated synaptic surface organizer

The sequence of this isoform differs from the canonical sequence as follows:
     1-121: Missing.
     122-167: GMSPEHAIRL...DNENKSDDEN → MVSPPLLIIS...LHGKVAMESL
     799-807: Missing.
     1277-1283: Missing.

Note: No experimental confirmation available.
Show »
Length:2,637
Mass (Da):292,259
Checksum:i13A01ED32D2A91BD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V106G3V106_HUMAN
HCG38403, isoform CRA_b
TENM2 hCG_38403
2,653Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VNQ3F8VNQ3_HUMAN
Teneurin-2
TENM2
2,535Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti2384L → P in BAA86441 (PubMed:10574461).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_060129728N → S. Corresponds to variant dbSNP:rs6862925Ensembl.1
Natural variantiVAR_0289461719V → F. Corresponds to variant dbSNP:rs11957063Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0450191 – 121Missing in isoform 2. CuratedAdd BLAST121
Alternative sequenceiVSP_045020122 – 167GMSPE…SDDEN → MVSPPLLIISVAGTIECKPD HLLWRPGSTSPQSVSFLHGK VAMESL in isoform 2. CuratedAdd BLAST46
Alternative sequenceiVSP_045021799 – 807Missing in isoform 2. Curated9
Alternative sequenceiVSP_0450221277 – 1283Missing in isoform 2. Curated7

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC008464 Genomic DNA No translation available.
AC008601 Genomic DNA No translation available.
AC008634 Genomic DNA No translation available.
AC008637 Genomic DNA No translation available.
AC008642 Genomic DNA No translation available.
AC008705 Genomic DNA No translation available.
AC008708 Genomic DNA No translation available.
AC011369 Genomic DNA No translation available.
AC011384 Genomic DNA No translation available.
AC026689 Genomic DNA No translation available.
AC091820 Genomic DNA No translation available.
AC093304 Genomic DNA No translation available.
AC113372 Genomic DNA No translation available.
AB032953 mRNA Translation: BAA86441.2
AL137500 mRNA Translation: CAB70774.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T46253

NCBI Reference Sequences

More...
RefSeqi
NP_001073897.2, NM_001080428.2
XP_016865149.1, XM_017009660.1 [Q9NT68-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000518659; ENSP00000429430; ENSG00000145934 [Q9NT68-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57451

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57451

UCSC genome browser

More...
UCSCi
uc031slx.2 human [Q9NT68-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008464 Genomic DNA No translation available.
AC008601 Genomic DNA No translation available.
AC008634 Genomic DNA No translation available.
AC008637 Genomic DNA No translation available.
AC008642 Genomic DNA No translation available.
AC008705 Genomic DNA No translation available.
AC008708 Genomic DNA No translation available.
AC011369 Genomic DNA No translation available.
AC011384 Genomic DNA No translation available.
AC026689 Genomic DNA No translation available.
AC091820 Genomic DNA No translation available.
AC093304 Genomic DNA No translation available.
AC113372 Genomic DNA No translation available.
AB032953 mRNA Translation: BAA86441.2
AL137500 mRNA Translation: CAB70774.1
PIRiT46253
RefSeqiNP_001073897.2, NM_001080428.2
XP_016865149.1, XM_017009660.1 [Q9NT68-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6CMXelectron microscopy3.10A846-2774[»]
SMRiQ9NT68
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiQ9NT68, 6 interactors
STRINGi9606.ENSP00000429430

Protein family/group databases

TCDBi9.B.87.1.20 the selenoprotein p receptor (selp-receptor) family

PTM databases

GlyConnecti1796
iPTMnetiQ9NT68
PhosphoSitePlusiQ9NT68

Polymorphism and mutation databases

BioMutaiTENM2
DMDMi290457667

Proteomic databases

EPDiQ9NT68
jPOSTiQ9NT68
MassIVEiQ9NT68
MaxQBiQ9NT68
PaxDbiQ9NT68
PeptideAtlasiQ9NT68
PRIDEiQ9NT68
ProteomicsDBi82603 [Q9NT68-1]

Genome annotation databases

EnsembliENST00000518659; ENSP00000429430; ENSG00000145934 [Q9NT68-1]
GeneIDi57451
KEGGihsa:57451
UCSCiuc031slx.2 human [Q9NT68-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57451
DisGeNETi57451

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TENM2
HGNCiHGNC:29943 TENM2
HPAiHPA038018
HPA038420
HPA068691
MIMi610119 gene
neXtProtiNX_Q9NT68
OpenTargetsiENSG00000145934

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1225 Eukaryota
KOG4659 Eukaryota
ENOG410XQQD LUCA
GeneTreeiENSGT00950000182725
HOGENOMiHOG000231701
InParanoidiQ9NT68
OMAiNNNPAHK
OrthoDBi7516at2759
PhylomeDBiQ9NT68
TreeFamiTF316833

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TENM2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57451
PharosiQ9NT68

Protein Ontology

More...
PROi
PR:Q9NT68

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000145934 Expressed in 153 organ(s), highest expression level in left ventricle myocardium
ExpressionAtlasiQ9NT68 baseline and differential

Family and domain databases

Gene3Di2.120.10.30, 2 hits
InterProiView protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR008969 CarboxyPept-like_regulatory
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR011044 Quino_amine_DH_bsu
IPR022385 Rhs_assc_core
IPR027689 Ten-2/3
IPR009471 Ten_N
IPR028916 Tox-GHH_dom
IPR006530 YD
PANTHERiPTHR11219:SF8 PTHR11219:SF8, 1 hit
PfamiView protein in Pfam
PF06484 Ten_N, 1 hit
PF15636 Tox-GHH, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 8 hits
SM00179 EGF_CA, 2 hits
SUPFAMiSSF49464 SSF49464, 1 hit
SSF50969 SSF50969, 1 hit
TIGRFAMsiTIGR03696 Rhs_assc_core, 1 hit
TIGR01643 YD_repeat_2x, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 8 hits
PS01186 EGF_2, 7 hits
PS50026 EGF_3, 5 hits
PS51361 TENEURIN_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTEN2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NT68
Secondary accession number(s): Q9ULU2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 2, 2010
Last modified: November 13, 2019
This is version 143 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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