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UniProtKB - Q9NSI6 (BRWD1_HUMAN)

Entry version 200 (23 Feb 2022)
Sequence version 4 (30 Nov 2010)
Previous versions | rss
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Protein

Bromodomain and WD repeat-containing protein 1

Gene

BRWD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a transcriptional activator. May be involved in chromatin remodeling (By similarity).

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9NSI6

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-1266695, Interleukin-7 signaling
R-HSA-3247509, Chromatin modifying enzymes

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9NSI6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bromodomain and WD repeat-containing protein 1
Alternative name(s):
WD repeat-containing protein 9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BRWD1
Synonyms:C21orf107, WDR9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:12760, BRWD1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		617824, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NSI6

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000185658

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		54014

Open Targets

More...OpenTargetsi		ENSG00000185658

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134906879

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9NSI6, Tbio

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL3351192

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		BRWD1

Domain mapping of disease mutations (DMDM)

More...DMDMi		313104296

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000508881 – 2320Bromodomain and WD repeat-containing protein 1Add BLAST2320

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei687PhosphothreonineBy similarity1
Modified residuei696PhosphoserineCombined sources1
Modified residuei701PhosphoserineCombined sources1
Modified residuei710PhosphoserineCombined sources1
Modified residuei1289PhosphoserineCombined sources1
Modified residuei1475PhosphoserineCombined sources1
Modified residuei1477PhosphothreonineCombined sources1
Modified residuei1479PhosphoserineCombined sources1
Modified residuei1605PhosphoserineCombined sources1
Modified residuei1607PhosphoserineCombined sources1
Modified residuei1678PhosphoserineCombined sources1
Modified residuei1683PhosphoserineCombined sources1
Modified residuei1686PhosphoserineCombined sources1
Modified residuei1755PhosphoserineBy similarity1
Modified residuei1756PhosphoserineBy similarity1
Modified residuei1786PhosphoserineBy similarity1
Modified residuei1788PhosphoserineBy similarity1
Modified residuei1793PhosphoserineBy similarity1
Modified residuei1820PhosphoserineBy similarity1
Modified residuei1867PhosphothreonineBy similarity1
Modified residuei1871PhosphoserineBy similarity1
Modified residuei1904PhosphoserineCombined sources1
Modified residuei1905PhosphoserineCombined sources1
Modified residuei1907PhosphoserineCombined sources1
Modified residuei1910PhosphoserineCombined sources1
Modified residuei1943PhosphoserineCombined sources1
Modified residuei1955PhosphothreonineBy similarity1
Modified residuei2018PhosphoserineCombined sources1
Modified residuei2020PhosphoserineCombined sources1
Modified residuei2052PhosphoserineBy similarity1
Modified residuei2164PhosphothreonineBy similarity1
Modified residuei2166PhosphoserineBy similarity1
Isoform B (identifier: Q9NSI6-2)
Modified residuei2214PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9NSI6

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9NSI6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9NSI6

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9NSI6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NSI6

PeptideAtlas

More...PeptideAtlasi		Q9NSI6

PRoteomics IDEntifications database

More...PRIDEi		Q9NSI6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		66890
82555 [Q9NSI6-1]
82556 [Q9NSI6-2]
82557 [Q9NSI6-3]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9NSI6, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NSI6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NSI6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000185658, Expressed in caudate nucleus and 224 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9NSI6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NSI6, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000185658, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SMARCA4.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		119828, 36 interactors

Protein interaction database and analysis system

More...IntActi		Q9NSI6, 46 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000330753

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		Q9NSI6

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9NSI6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

12320
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9NSI6

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q9NSI6

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati184 – 223WD 1Add BLAST40
Repeati226 – 265WD 2Add BLAST40
Repeati268 – 311WD 3Add BLAST44
Repeati322 – 365WD 4Add BLAST44
Repeati366 – 405WD 5Add BLAST40
Repeati424 – 463WD 6Add BLAST40
Repeati466 – 506WD 7Add BLAST41
Repeati514 – 553WD 8Add BLAST40
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1177 – 1247Bromo 1PROSITE-ProRule annotationAdd BLAST71
Domaini1330 – 1400Bromo 2PROSITE-ProRule annotationAdd BLAST71

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni668 – 691DisorderedSequence analysisAdd BLAST24
Regioni809 – 867DisorderedSequence analysisAdd BLAST59
Regioni895 – 925DisorderedSequence analysisAdd BLAST31
Regioni1271 – 1304DisorderedSequence analysisAdd BLAST34
Regioni1434 – 1593DisorderedSequence analysisAdd BLAST160
Regioni1670 – 1805DisorderedSequence analysisAdd BLAST136
Regioni1817 – 1839DisorderedSequence analysisAdd BLAST23
Regioni1862 – 1899DisorderedSequence analysisAdd BLAST38
Regioni2014 – 2077DisorderedSequence analysisAdd BLAST64
Regioni2112 – 2184DisorderedSequence analysisAdd BLAST73

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi810 – 836Polar residuesSequence analysisAdd BLAST27
Compositional biasi839 – 855Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi1470 – 1507Polar residuesSequence analysisAdd BLAST38
Compositional biasi1521 – 1550Polar residuesSequence analysisAdd BLAST30
Compositional biasi1560 – 1584Polar residuesSequence analysisAdd BLAST25
Compositional biasi1673 – 1697Basic and acidic residuesSequence analysisAdd BLAST25
Compositional biasi1712 – 1732Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi1751 – 1768Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi1769 – 1784Polar residuesSequence analysisAdd BLAST16
Compositional biasi1865 – 1881Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi2021 – 2043Basic and acidic residuesSequence analysisAdd BLAST23
Compositional biasi2044 – 2077Polar residuesSequence analysisAdd BLAST34
Compositional biasi2116 – 2137Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi2138 – 2169Polar residuesSequence analysisAdd BLAST32

Keywords - Domaini

Bromodomain, Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0644, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183107

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001108_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NSI6

Identification of Orthologs from Complete Genome Data

More...OMAi		GAMYQHI

Database of Orthologous Groups

More...OrthoDBi		240778at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NSI6

TreeFam database of animal gene trees

More...TreeFami		TF324197

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.920.10, 2 hits
2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR018359, Bromodomain_CS
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR036322, WD40_repeat_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00439, Bromodomain, 2 hits
PF00400, WD40, 5 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00503, BROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00297, BROMO, 2 hits
SM00320, WD40, 8 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47370, SSF47370, 2 hits
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00633, BROMODOMAIN_1, 1 hit
PS50014, BROMODOMAIN_2, 2 hits
PS00678, WD_REPEATS_1, 2 hits
PS50082, WD_REPEATS_2, 6 hits
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform A (identifier: Q9NSI6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEPSSARRP VPLIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK 
        60         70         80         90        100
RLDWEGNEHN RSYEELVLSN KHVAPDHLLQ ICQRIGPMLD KEIPPSISRV 
       110        120        130        140        150
TSLLGAGRQS LLRTAKDCRH TVWKGSAFAA LHRGRPPEMP VNYGSPPNLV 
       160        170        180        190        200
EIHRGKQLTG CSTFSTAFPG TMYQHIKMHR RILGHLSAVY CVAFDRTGHR 
       210        220        230        240        250
IFTGSDDCLV KIWSTHNGRL LSTLRGHSAE ISDMAVNYEN TMIAAGSCDK 
       260        270        280        290        300
IIRVWCLRTC APVAVLQGHT GSITSLQFSP MAKGSQRYMV STGADGTVCF 
       310        320        330        340        350
WQWDLESLKF SPRPLKFTEK PRPGVQMLCS SFSVGGMFLA TGSTDHVIRM 
       360        370        380        390        400
YFLGFEAPEK IAELESHTDK VDSIQFCNNG DRFLSGSRDG TARIWRFEQL 
       410        420        430        440        450
EWRSILLDMA TRISGDLSSE EERFMKPKVT MIAWNQNDSI VVTAVNDHVL 
       460        470        480        490        500
KVWNSYTGQL LHNLMGHADE VFVLETHPFD SRIMLSAGHD GSIFIWDITK 
       510        520        530        540        550
GTKMKHYFNM IEGQGHGAVF DCKFSQDGQH FACTDSHGHL LIFGFGCSKP 
       560        570        580        590        600
YEKIPDQMFF HTDYRPLIRD SNNYVLDEQT QQAPHLMPPP FLVDVDGNPH 
       610        620        630        640        650
PTKYQRLVPG RENSADEHLI PQLGYVATSD GEVIEQIISL QTNDNDERSP 
       660        670        680        690        700
ESSILDGMIR QLQQQQDQRM GADQDTIPRG LSNGEETPRR GFRRLSLDIQ 
       710        720        730        740        750
SPPNIGLRRS GQVEGVRQMH QNAPRSQIAT ERDLQAWKRR VVVPEVPLGI 
       760        770        780        790        800
FRKLEDFRLE KGEEERNLYI IGRKRKTLQL SHKSDSVVLV SQSRQRTCRR 
       810        820        830        840        850
KYPNYGRRNR SWRELSSGNE SSSSVRHETS CDQSEGSGSS EEDEWRSDRK 
       860        870        880        890        900
SESYSESSSD SSSRYSDWTA DAGINLQPPL RTSCRRRITR FCSSSEDEIS 
       910        920        930        940        950
TENLSPPKRR RKRKKENKPK KENLRRMTPA ELANMEHLYE FHPPVWITDT 
       960        970        980        990       1000
TLRKSPFVPQ MGDEVIYFRQ GHEAYIEAVR RNNIYELNPN KEPWRKMDLR 
      1010       1020       1030       1040       1050
DQELVKIVGI RYEVGPPTLC CLKLAFIDPA TGKLMDKSFS IRYHDMPDVI 
      1060       1070       1080       1090       1100
DFLVLRQFYD EARQRNWQSC DRFRSIIDDA WWFGTVLSQE PYQPQYPDSH 
      1110       1120       1130       1140       1150
FQCYIVRWDN TEIEKLSPWD MEPIPDNVDP PEELGASISV TTDELEKLLY 
      1160       1170       1180       1190       1200
KPQAGEWGQK SRDEECDRII SGIDQLLNLD IAAAFAGPVD LCTYPKYCTV 
      1210       1220       1230       1240       1250
VAYPTDLYTI RMRLVNRFYR RLSALVWEVR YIEHNARTFN EPESVIARSA 
      1260       1270       1280       1290       1300
KKITDQLLKF IKNQHCTNIS ELSNTSENDE QNAEDLDDSD LPKTSSGRRR 
      1310       1320       1330       1340       1350
VHDGKKSIRA TNYVESNWKK QCKELVNLIF QCEDSEPFRQ PVDLVEYPDY 
      1360       1370       1380       1390       1400
RDIIDTPMDF GTVRETLDAG NYDSPLEFCK DIRLIFSNAK AYTPNKRSKI 
      1410       1420       1430       1440       1450
YSMTLRLSAL FEEKMKKISS DFKIGQKFNE KLRRSQRFKQ RQNCKGDSQP 
      1460       1470       1480       1490       1500
NKSIRNLKPK RLKSQTKIIP ELVGSPTQST SSRTAYLGTH KTSAGISSGV 
      1510       1520       1530       1540       1550
TSGDSSDSAE SSERRKRNRP ITNGSTLSES EVEDSLATSL SSSASSSSEE 
      1560       1570       1580       1590       1600
SKESSRARES SSRSGLSRSS NLRVTRTRAA QRKTGPVSLA NGCGRKATRK 
      1610       1620       1630       1640       1650
RVYLSDSDNN SLETGEILKA RAGNNRKVLR KCAAVAANKI KLMSDVEENS 
      1660       1670       1680       1690       1700
SSESVCSGRK LPHRNASAVA RKKLLHNSED EQSLKSEIEE EELKDENQLL 
      1710       1720       1730       1740       1750
PVSSSHTAQS NVDESENRDS ESESDLRVAR KNWHANGYKS HTPAPSKTKF 
      1760       1770       1780       1790       1800
LKIESSEEDS KSHDSDHACN RTAGPSTSVQ KLKAESISEE ADSEPGRSGG 
      1810       1820       1830       1840       1850
RKYNTFHKNA SFFKKTKILS DSEDSESEEQ DREDGKCHKM EMNPISGNLN 
      1860       1870       1880       1890       1900
CDPIAMSQCS SDHGCETDLD SDDDKIEKPN NFMKDSASQD NGLSRKISRK 
      1910       1920       1930       1940       1950
RVCSSDSDSS LQVVKKSSKA RTGLLRITRR CAATAANKIK LMSDVEDVSL 
      1960       1970       1980       1990       2000
ENVHTRSKNG RKKPLHLACT TAKKKLSDCE GSVHCEVPSE QYACEGKPPD 
      2010       2020       2030       2040       2050
PDSEGSTKVL SQALNGDSDS EDMLNSEHKH RHTNIHKIDA PSKRKSSSVT 
      2060       2070       2080       2090       2100
SSGEDSKSHI PGSETDRTFS SESTLAQKAT AENNFEVELN YGLRRWNGRR 
      2110       2120       2130       2140       2150
LRTYGKAPFS KTKVIHDSQE TAEKEVKRKR SHPELENVKI SETTGNSKFR 
      2160       2170       2180       2190       2200
PDTSSKSSDL GSVTESDIDC TDNTKTKRRK TKGKAKVVRK EFVPRDREPN 
      2210       2220       2230       2240       2250
TKVRTCMHNQ KDAVQMPSET LKAKMVPEKV PRRCATVAAN KIKIMSNLKE 
      2260       2270       2280       2290       2300
TISGPENVWI RKSSRKLPHR NASAAAKKKL LNVYKEDDTT INSESEKELE 
      2310       2320
DINRKMLFLR GFRSWKENAQ
Length:2,320
Mass (Da):262,936
Last modified:November 30, 2010 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i109714D79B9057E9
GO
Isoform B (identifier: Q9NSI6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2191-2320: EFVPRDREPN...GFRSWKENAQ → GKTFTANISK...NVLDFNGCTL

Show »
Length:2,269
Mass (Da):257,238
Checksum:iEF2D6F3B745BB4EE
GO
Isoform C (identifier: Q9NSI6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2191-2285: EFVPRDREPN...AKKKLLNVYK → DKTFSPVYL
     2286-2320: Missing.

Show »
Length:2,199
Mass (Da):248,953
Checksum:iD0B8757ED0AF6E32
GO
Isoform D (identifier: Q9NSI6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     117-120: DCRH → GTLI
     121-2320: Missing.

Show »
Length:120
Mass (Da):13,558
Checksum:iF31E4C9728C92359
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y463H0Y463_HUMAN
Bromodomain and WD repeat-containin...
BRWD1
548Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y500H0Y500_HUMAN
Bromodomain and WD repeat-containin...
BRWD1
409Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C409H7C409_HUMAN
Bromodomain and WD repeat-containin...
BRWD1
452Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y5I9H0Y5I9_HUMAN
Bromodomain and WD repeat-containin...
BRWD1
467Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BZR9H7BZR9_HUMAN
Bromodomain and WD repeat-containin...
BRWD1
640Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y4R9H0Y4R9_HUMAN
Bromodomain and WD repeat-containin...
BRWD1
266Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y4A7H0Y4A7_HUMAN
Bromodomain and WD repeat-containin...
BRWD1
235Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA10896 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1560 – 1562SSS → GTR in CAA10896 (PubMed:9480850).Curated3
Sequence conflicti1840M → V in AK002177 (PubMed:14702039).Curated1
Sequence conflicti2134E → G in AK002177 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02643583Q → E1 PublicationCorresponds to variant dbSNP:rs2056844Ensembl.1
Natural variantiVAR_0264361511S → P1 PublicationCorresponds to variant dbSNP:rs2183573Ensembl.1
Natural variantiVAR_0264371699L → P5 PublicationsCorresponds to variant dbSNP:rs1041439Ensembl.1
Natural variantiVAR_0575842156K → R. Corresponds to variant dbSNP:rs2234548Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_044245117 – 120DCRH → GTLI in isoform D. 1 Publication4
Alternative sequenceiVSP_044246121 – 2320Missing in isoform D. 1 PublicationAdd BLAST2200
Alternative sequenceiVSP_0185262191 – 2320EFVPR…KENAQ → GKTFTANISKTVRRQRQSKR PRLSVDDNDWEDLDYAKSKR VLRRSKIKTRNQGRRTVRYH DGDDDRSLENVLDFNGCTL in isoform B. 4 PublicationsAdd BLAST130
Alternative sequenceiVSP_0185272191 – 2285EFVPR…LNVYK → DKTFSPVYL in isoform C. 1 PublicationAdd BLAST95
Alternative sequenceiVSP_0185282286 – 2320Missing in isoform C. 1 PublicationAdd BLAST35

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ238214 mRNA Translation: CAC37033.2
AJ292465 mRNA Translation: CAC44371.1
AJ292466 mRNA Translation: CAC44372.1
AB080586 mRNA Translation: BAD74071.1
AB080587 mRNA Translation: BAD74072.1
AF064861 Genomic DNA No translation available.
AF129408 Genomic DNA No translation available.
BC064602 mRNA Translation: AAH64602.1
AL163279 Genomic DNA Translation: CAB90452.1
AJ222636 mRNA Translation: CAA10896.1 Frameshift.
AK002177 mRNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS13662.1 [Q9NSI6-1]
CCDS13663.1 [Q9NSI6-2]
CCDS33557.1 [Q9NSI6-4]

NCBI Reference Sequences

More...RefSeqi		NP_001007247.1, NM_001007246.2 [Q9NSI6-4]
NP_061836.2, NM_018963.4 [Q9NSI6-1]
NP_387505.1, NM_033656.3 [Q9NSI6-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000333229; ENSP00000330753; ENSG00000185658
ENST00000341322; ENSP00000342106; ENSG00000185658 [Q9NSI6-4]
ENST00000342449; ENSP00000344333; ENSG00000185658 [Q9NSI6-2]
ENST00000380800; ENSP00000370178; ENSG00000185658 [Q9NSI6-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		54014

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:54014

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000342449.8; ENSP00000344333.3; NM_033656.4; NP_387505.1 [Q9NSI6-2]

UCSC genome browser

More...UCSCi		uc002yxk.3, human [Q9NSI6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ238214 mRNA Translation: CAC37033.2
AJ292465 mRNA Translation: CAC44371.1
AJ292466 mRNA Translation: CAC44372.1
AB080586 mRNA Translation: BAD74071.1
AB080587 mRNA Translation: BAD74072.1
AF064861 Genomic DNA No translation available.
AF129408 Genomic DNA No translation available.
BC064602 mRNA Translation: AAH64602.1
AL163279 Genomic DNA Translation: CAB90452.1
AJ222636 mRNA Translation: CAA10896.1 Frameshift.
AK002177 mRNA No translation available.
CCDSiCCDS13662.1 [Q9NSI6-1]
CCDS13663.1 [Q9NSI6-2]
CCDS33557.1 [Q9NSI6-4]
RefSeqiNP_001007247.1, NM_001007246.2 [Q9NSI6-4]
NP_061836.2, NM_018963.4 [Q9NSI6-1]
NP_387505.1, NM_033656.3 [Q9NSI6-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3Q2EX-ray1.74A1310-1430[»]
SMRiQ9NSI6
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi119828, 36 interactors
IntActiQ9NSI6, 46 interactors
STRINGi9606.ENSP00000330753

Chemistry databases

BindingDBiQ9NSI6
ChEMBLiCHEMBL3351192

PTM databases

GlyGeniQ9NSI6, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ9NSI6
PhosphoSitePlusiQ9NSI6

Genetic variation databases

BioMutaiBRWD1
DMDMi313104296

Proteomic databases

EPDiQ9NSI6
jPOSTiQ9NSI6
MassIVEiQ9NSI6
MaxQBiQ9NSI6
PaxDbiQ9NSI6
PeptideAtlasiQ9NSI6
PRIDEiQ9NSI6
ProteomicsDBi66890
82555 [Q9NSI6-1]
82556 [Q9NSI6-2]
82557 [Q9NSI6-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		23299, 106 antibodies from 22 providers

The DNASU plasmid repository

More...DNASUi		54014

Genome annotation databases

EnsembliENST00000333229; ENSP00000330753; ENSG00000185658
ENST00000341322; ENSP00000342106; ENSG00000185658 [Q9NSI6-4]
ENST00000342449; ENSP00000344333; ENSG00000185658 [Q9NSI6-2]
ENST00000380800; ENSP00000370178; ENSG00000185658 [Q9NSI6-3]
GeneIDi54014
KEGGihsa:54014
MANE-SelectiENST00000342449.8; ENSP00000344333.3; NM_033656.4; NP_387505.1 [Q9NSI6-2]
UCSCiuc002yxk.3, human [Q9NSI6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54014
DisGeNETi54014

GeneCards: human genes, protein and diseases

More...GeneCardsi		BRWD1
HGNCiHGNC:12760, BRWD1
HPAiENSG00000185658, Low tissue specificity
MIMi617824, gene
neXtProtiNX_Q9NSI6
OpenTargetsiENSG00000185658
PharmGKBiPA134906879
VEuPathDBiHostDB:ENSG00000185658

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0644, Eukaryota
GeneTreeiENSGT00950000183107
HOGENOMiCLU_001108_0_1_1
InParanoidiQ9NSI6
OMAiGAMYQHI
OrthoDBi240778at2759
PhylomeDBiQ9NSI6
TreeFamiTF324197

Enzyme and pathway databases

PathwayCommonsiQ9NSI6
ReactomeiR-HSA-1266695, Interleukin-7 signaling
R-HSA-3247509, Chromatin modifying enzymes
SignaLinkiQ9NSI6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		54014, 29 hits in 1089 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		BRWD1, human
EvolutionaryTraceiQ9NSI6

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		BRWD1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		54014
PharosiQ9NSI6, Tbio

Protein Ontology

More...PROi		PR:Q9NSI6
RNActiQ9NSI6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000185658, Expressed in caudate nucleus and 224 other tissues
ExpressionAtlasiQ9NSI6, baseline and differential
GenevisibleiQ9NSI6, HS

Family and domain databases

Gene3Di1.20.920.10, 2 hits
2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR018359, Bromodomain_CS
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR036322, WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00439, Bromodomain, 2 hits
PF00400, WD40, 5 hits
PRINTSiPR00503, BROMODOMAIN
SMARTiView protein in SMART
SM00297, BROMO, 2 hits
SM00320, WD40, 8 hits
SUPFAMiSSF47370, SSF47370, 2 hits
SSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00633, BROMODOMAIN_1, 1 hit
PS50014, BROMODOMAIN_2, 2 hits
PS00678, WD_REPEATS_1, 2 hits
PS50082, WD_REPEATS_2, 6 hits
PS50294, WD_REPEATS_REGION, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBRWD1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NSI6
Secondary accession number(s): C9JK25
, O43721, Q5R2V0, Q5R2V1, Q6P2D1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: November 30, 2010
Last modified: February 23, 2022
This is version 200 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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