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Entry version 137 (08 May 2019)
Sequence version 1 (01 Oct 2000)
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Protein

Relaxin-3 receptor 1

Gene

RXFP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-418594 G alpha (i) signalling events
R-HSA-444821 Relaxin receptors

Protein family/group databases

Transport Classification Database

More...
TCDBi
9.A.14.13.21 the g-protein-coupled receptor (gpcr) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Relaxin-3 receptor 1
Short name:
RLN3 receptor 1
Alternative name(s):
G protein-coupled receptor SALPR
G-protein coupled receptor GPCR135
Relaxin family peptide receptor 3
Somatostatin- and angiotensin-like peptide receptor
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RXFP3
Synonyms:RLN3R1, SALPR
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24883 RXFP3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609445 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NSD7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 81ExtracellularSequence analysisAdd BLAST81
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei82 – 102Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini103 – 119CytoplasmicSequence analysisAdd BLAST17
Transmembranei120 – 140Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini141 – 156ExtracellularSequence analysisAdd BLAST16
Transmembranei157 – 177Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini178 – 215CytoplasmicSequence analysisAdd BLAST38
Transmembranei216 – 236Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini237 – 270ExtracellularSequence analysisAdd BLAST34
Transmembranei271 – 291Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini292 – 329CytoplasmicSequence analysisAdd BLAST38
Transmembranei330 – 350Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini351 – 356ExtracellularSequence analysis6
Transmembranei357 – 377Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini378 – 469CytoplasmicSequence analysisAdd BLAST92

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
51289

Open Targets

More...
OpenTargetsi
ENSG00000182631

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134868535

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL1628472

IUPHAR/BPS Guide to PHARMACOLOGY

More...
GuidetoPHARMACOLOGYi
353

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RXFP3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
20455271

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000701041 – 469Relaxin-3 receptor 1Add BLAST469

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi36N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi40N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi155 ↔ 247PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NSD7

PeptideAtlas

More...
PeptideAtlasi
Q9NSD7

PRoteomics IDEntifications database

More...
PRIDEi
Q9NSD7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
82537

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NSD7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NSD7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000182631 Expressed in 10 organ(s), highest expression level in right adrenal gland

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NSD7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA027833

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119440, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NSD7, 8 interactors

Molecular INTeraction database

More...
MINTi
Q9NSD7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000328708

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
Q9NSD7

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NSD7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3656 Eukaryota
ENOG410XRW9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182719

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000230485

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NSD7

KEGG Orthology (KO)

More...
KOi
K08397

Identification of Orthologs from Complete Genome Data

More...
OMAi
MKSKQGW

Database of Orthologous Groups

More...
OrthoDBi
880755at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NSD7

TreeFam database of animal gene trees

More...
TreeFami
TF330024

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00001 7tm_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00237 GPCRRHODOPSN

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9NSD7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQMADAATIA TMNKAAGGDK LAELFSLVPD LLEAANTSGN ASLQLPDLWW
60 70 80 90 100
ELGLELPDGA PPGHPPGSGG AESADTEARV RILISVVYWV VCALGLAGNL
110 120 130 140 150
LVLYLMKSMQ GWRKSSINLF VTNLALTDFQ FVLTLPFWAV ENALDFKWPF
160 170 180 190 200
GKAMCKIVSM VTSMNMYASV FFLTAMSVTR YHSVASALKS HRTRGHGRGD
210 220 230 240 250
CCGRSLGDSC CFSAKALCVW IWALAALASL PSAIFSTTVK VMGEELCLVR
260 270 280 290 300
FPDKLLGRDR QFWLGLYHSQ KVLLGFVLPL GIIILCYLLL VRFIADRRAA
310 320 330 340 350
GTKGGAAVAG GRPTGASARR LSKVTKSVTI VVLSFFLCWL PNQALTTWSI
360 370 380 390 400
LIKFNAVPFS QEYFLCQVYA FPVSVCLAHS NSCLNPVLYC LVRREFRKAL
410 420 430 440 450
KSLLWRIASP SITSMRPFTA TTKPEHEDQG LQAPAPPHAA AEPDLLYYPP
460
GVVVYSGGRY DLLPSSSAY
Length:469
Mass (Da):51,124
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i932E7B3001689F7B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D88437 mRNA Translation: BAA93001.1
AY236541 Genomic DNA Translation: AAO92063.1
AY394501 mRNA Translation: AAQ92315.1
BC113438 mRNA Translation: AAI13439.1
BC113440 mRNA Translation: AAI13441.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3900.1

NCBI Reference Sequences

More...
RefSeqi
NP_057652.1, NM_016568.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000330120; ENSP00000328708; ENSG00000182631
ENST00000616205; ENSP00000480733; ENSG00000277069

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51289

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51289

UCSC genome browser

More...
UCSCi
uc003jic.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D88437 mRNA Translation: BAA93001.1
AY236541 Genomic DNA Translation: AAO92063.1
AY394501 mRNA Translation: AAQ92315.1
BC113438 mRNA Translation: AAI13439.1
BC113440 mRNA Translation: AAI13441.1
CCDSiCCDS3900.1
RefSeqiNP_057652.1, NM_016568.3

3D structure databases

SMRiQ9NSD7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119440, 2 interactors
IntActiQ9NSD7, 8 interactors
MINTiQ9NSD7
STRINGi9606.ENSP00000328708

Chemistry databases

BindingDBiQ9NSD7
ChEMBLiCHEMBL1628472
GuidetoPHARMACOLOGYi353

Protein family/group databases

TCDBi9.A.14.13.21 the g-protein-coupled receptor (gpcr) family

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

PTM databases

iPTMnetiQ9NSD7
PhosphoSitePlusiQ9NSD7

Polymorphism and mutation databases

BioMutaiRXFP3
DMDMi20455271

Proteomic databases

PaxDbiQ9NSD7
PeptideAtlasiQ9NSD7
PRIDEiQ9NSD7
ProteomicsDBi82537

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
51289
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000330120; ENSP00000328708; ENSG00000182631
ENST00000616205; ENSP00000480733; ENSG00000277069
GeneIDi51289
KEGGihsa:51289
UCSCiuc003jic.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51289
DisGeNETi51289

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RXFP3
HGNCiHGNC:24883 RXFP3
HPAiHPA027833
MIMi609445 gene
neXtProtiNX_Q9NSD7
OpenTargetsiENSG00000182631
PharmGKBiPA134868535

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00950000182719
HOGENOMiHOG000230485
InParanoidiQ9NSD7
KOiK08397
OMAiMKSKQGW
OrthoDBi880755at2759
PhylomeDBiQ9NSD7
TreeFamiTF330024

Enzyme and pathway databases

ReactomeiR-HSA-418594 G alpha (i) signalling events
R-HSA-444821 Relaxin receptors

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
Relaxin/insulin-like_family_peptide_receptor_3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
51289

Protein Ontology

More...
PROi
PR:Q9NSD7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000182631 Expressed in 10 organ(s), highest expression level in right adrenal gland
GenevisibleiQ9NSD7 HS

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL3R1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NSD7
Secondary accession number(s): Q14DA5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: October 1, 2000
Last modified: May 8, 2019
This is version 137 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
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