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UniProtKB - Q9NS64 (RPRM_HUMAN)

Entry version 137 (23 Feb 2022)
Sequence version 1 (01 Oct 2000)
Previous versions | rss
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Protein

Protein reprimo

Gene

RPRM

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity).

By similarity

Miscellaneous

'Reprimo' signifies stop/repress.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9NS64

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9NS64

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein reprimo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPRM
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:24201, RPRM

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		612171, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NS64

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000177519

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei56 – 76HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		56475

Open Targets

More...OpenTargetsi		ENSG00000177519

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134937494

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9NS64, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		RPRM

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003127521 – 109Protein reprimoAdd BLAST109

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi7N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi18N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei98PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NS64

PeptideAtlas

More...PeptideAtlasi		Q9NS64

PRoteomics IDEntifications database

More...PRIDEi		Q9NS64

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9NS64, 2 sites

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NS64

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By p53/TP53, following X-ray irradiation.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000177519, Expressed in frontal cortex and 147 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NS64, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000177519, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q9NS64
With#Exp.IntAct
ADGRG3 [Q86Y34]3EBI-1052363,EBI-17979264
AMIGO1 [Q86WK6]3EBI-1052363,EBI-19125216
AQP6 [Q13520]3EBI-1052363,EBI-13059134
ARFIP1 [P53367]3EBI-1052363,EBI-2808808
ASGR2 - isoform 3 [P07307-3]3EBI-1052363,EBI-12808270
BNIP3 [Q12983]3EBI-1052363,EBI-749464
BSCL2 [J3KQ12]3EBI-1052363,EBI-11532900
BTNL9 - isoform 3 [Q6UXG8-3]3EBI-1052363,EBI-17953245
C16orf54 [Q6UWD8]3EBI-1052363,EBI-18041102
CD33 [P20138]3EBI-1052363,EBI-3906571
CD53 [P19397]3EBI-1052363,EBI-6657396
CD69 [Q07108]3EBI-1052363,EBI-2836595
CLDN5 [O00501]3EBI-1052363,EBI-18400628
CLDN7 [O95471]3EBI-1052363,EBI-740744
CLDN9 [O95484]3EBI-1052363,EBI-18341636
CLEC17A [Q6ZS10]4EBI-1052363,EBI-11977093
CLEC2D - isoform 2 [Q9UHP7-3]3EBI-1052363,EBI-11749983
COQ8A [Q8NI60]3EBI-1052363,EBI-745535
CXorf66 [Q5JRM2]3EBI-1052363,EBI-12823659
EHHADH [Q08426]3EBI-1052363,EBI-2339219
EMP1 [P54849]3EBI-1052363,EBI-4319440
FAM209A [Q5JX71]3EBI-1052363,EBI-18304435
FAM210B [Q96KR6]3EBI-1052363,EBI-18938272
FATE1 [Q969F0]6EBI-1052363,EBI-743099
FBXL19 - isoform 2 [Q6PCT2-2]3EBI-1052363,EBI-11959077
FCGR1A [P12314]3EBI-1052363,EBI-2869867
FFAR2 [O15552]3EBI-1052363,EBI-2833872
FGD2 [Q7Z6J4]3EBI-1052363,EBI-1057190
FKBP7 [Q9Y680]3EBI-1052363,EBI-3918971
FNDC9 [Q8TBE3]3EBI-1052363,EBI-12142257
GAD2 [Q05329]3EBI-1052363,EBI-9304251
GJA5 [P36382]3EBI-1052363,EBI-750433
GJB3 [O75712]3EBI-1052363,EBI-3908586
GJB5 [O95377]3EBI-1052363,EBI-3909454
GNG13 [Q9P2W3]3EBI-1052363,EBI-11427343
GPR37L1 [O60883]3EBI-1052363,EBI-2927498
GPR42 [O15529]3EBI-1052363,EBI-18076404
HHLA2 [Q9UM44]3EBI-1052363,EBI-2867874
HIP1 [O00291]3EBI-1052363,EBI-473886
HSD17B13 [Q7Z5P4]3EBI-1052363,EBI-18053395
KCNJ6 [P48051]3EBI-1052363,EBI-12017638
LAPTM5 [Q13571]3EBI-1052363,EBI-2865663
LHFPL5 [Q8TAF8]3EBI-1052363,EBI-2820517
LPAR6 [P43657]3EBI-1052363,EBI-2876949
MPP1 [Q00013]3EBI-1052363,EBI-711788
MS4A4A [Q96JQ5]4EBI-1052363,EBI-12820341
MTIF3 [Q9H2K0]3EBI-1052363,EBI-3923617
OPRD1 [P41143]3EBI-1052363,EBI-2624456
OPRM1 - isoform 10 [P35372-10]3EBI-1052363,EBI-12807478
PBX3 [Q96AL5]3EBI-1052363,EBI-741171
PDZK1IP1 [Q13113]3EBI-1052363,EBI-716063
PLEKHF2 [Q9H8W4]3EBI-1052363,EBI-742388
PNKP [Q96T60]3EBI-1052363,EBI-1045072
SCAND1 [P57086]3EBI-1052363,EBI-745846
SDCBP [O00560]3EBI-1052363,EBI-727004
SENP2 [Q9HC62]3EBI-1052363,EBI-714881
SLC18A1 - isoform 3 [P54219-3]3EBI-1052363,EBI-17595455
SLC38A1 [Q9H2H9]3EBI-1052363,EBI-9978441
SMIM3 [Q9BZL3]3EBI-1052363,EBI-741850
SNX11 [Q9Y5W9]3EBI-1052363,EBI-10329449
SNX12 - isoform 1 [Q9UMY4-1]3EBI-1052363,EBI-22419305
SNX3 [O60493]3EBI-1052363,EBI-727209
SPACA1 [Q9HBV2]3EBI-1052363,EBI-17498703
STOM [P27105]3EBI-1052363,EBI-1211440
SUSD3 [Q96L08]3EBI-1052363,EBI-18194029
SYT16 [Q17RD7]3EBI-1052363,EBI-10238936
TM4SF18 [Q96CE8]3EBI-1052363,EBI-13351685
TMEM106C [Q9BVX2]3EBI-1052363,EBI-2821497
TMEM237 - isoform 2 [Q96Q45-2]3EBI-1052363,EBI-10982110
TMEM79 [Q9BSE2]6EBI-1052363,EBI-8649725
TMEM80 [Q96HE8]3EBI-1052363,EBI-11742770
TMEM86B [Q8N661]3EBI-1052363,EBI-2548832
TSPO2 [Q5TGU0]3EBI-1052363,EBI-12195249
TTPA [P49638]3EBI-1052363,EBI-10210710
WDFY2 [Q96P53]3EBI-1052363,EBI-9478589
ZDHHC22 [Q8N966]3EBI-1052363,EBI-10268111

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		121145, 96 interactors

Protein interaction database and analysis system

More...IntActi		Q9NS64, 77 interactors

Molecular INTeraction database

More...MINTi		Q9NS64

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000314946

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9NS64, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the reprimo family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502S262, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000010523

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_170456_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NS64

Identification of Orthologs from Complete Genome Data

More...OMAi		EEFFCCN

Database of Orthologous Groups

More...OrthoDBi		1529294at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NS64

TreeFam database of animal gene trees

More...TreeFami		TF332720

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR033356, Reprimo
IPR043383, Reprimo_fam

The PANTHER Classification System

More...PANTHERi		PTHR28649, PTHR28649, 1 hit
PTHR28649:SF2, PTHR28649:SF2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9NS64-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNPALGNQTD VAGLFLANSS EALERAVRCC TQASVVTDDG FAEGGPDERS 
        60         70         80         90        100
LYIMRVVQIA VMCVLSLTVV FGIFFLGCNL LIKSEGMINF LVKDRRPSKE 

VEAVVVGPY
Length:109
Mass (Da):11,774
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7026A0AB1FB6BE62
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB043585 mRNA Translation: BAB01513.1
AK311958 mRNA Translation: BAG34898.1
AK074808 mRNA Translation: BAG52007.1
AC012501 Genomic DNA Translation: AAY14783.1
CH471058 Genomic DNA Translation: EAX11467.1
BC002908 mRNA Translation: AAH02908.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS2198.1

NCBI Reference Sequences

More...RefSeqi		NP_062819.1, NM_019845.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000325926; ENSP00000314946; ENSG00000177519

Database of genes from NCBI RefSeq genomes

More...GeneIDi		56475

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:56475

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000325926.4; ENSP00000314946.3; NM_019845.3; NP_062819.1

UCSC genome browser

More...UCSCi		uc002tyq.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB043585 mRNA Translation: BAB01513.1
AK311958 mRNA Translation: BAG34898.1
AK074808 mRNA Translation: BAG52007.1
AC012501 Genomic DNA Translation: AAY14783.1
CH471058 Genomic DNA Translation: EAX11467.1
BC002908 mRNA Translation: AAH02908.1
CCDSiCCDS2198.1
RefSeqiNP_062819.1, NM_019845.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi121145, 96 interactors
IntActiQ9NS64, 77 interactors
MINTiQ9NS64
STRINGi9606.ENSP00000314946

PTM databases

GlyGeniQ9NS64, 2 sites
PhosphoSitePlusiQ9NS64

Genetic variation databases

BioMutaiRPRM

Proteomic databases

PaxDbiQ9NS64
PeptideAtlasiQ9NS64
PRIDEiQ9NS64

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		54148, 87 antibodies from 14 providers

The DNASU plasmid repository

More...DNASUi		56475

Genome annotation databases

EnsembliENST00000325926; ENSP00000314946; ENSG00000177519
GeneIDi56475
KEGGihsa:56475
MANE-SelectiENST00000325926.4; ENSP00000314946.3; NM_019845.3; NP_062819.1
UCSCiuc002tyq.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		56475
DisGeNETi56475

GeneCards: human genes, protein and diseases

More...GeneCardsi		RPRM
HGNCiHGNC:24201, RPRM
HPAiENSG00000177519, Low tissue specificity
MIMi612171, gene
neXtProtiNX_Q9NS64
OpenTargetsiENSG00000177519
PharmGKBiPA134937494
VEuPathDBiHostDB:ENSG00000177519

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502S262, Eukaryota
GeneTreeiENSGT00390000010523
HOGENOMiCLU_170456_0_0_1
InParanoidiQ9NS64
OMAiEEFFCCN
OrthoDBi1529294at2759
PhylomeDBiQ9NS64
TreeFamiTF332720

Enzyme and pathway databases

PathwayCommonsiQ9NS64
SignaLinkiQ9NS64

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		56475, 2 hits in 1043 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		56475
PharosiQ9NS64, Tbio

Protein Ontology

More...PROi		PR:Q9NS64
RNActiQ9NS64, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000177519, Expressed in frontal cortex and 147 other tissues
GenevisibleiQ9NS64, HS

Family and domain databases

InterProiView protein in InterPro
IPR033356, Reprimo
IPR043383, Reprimo_fam
PANTHERiPTHR28649, PTHR28649, 1 hit
PTHR28649:SF2, PTHR28649:SF2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRPRM_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NS64
Secondary accession number(s): B2R4V1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: October 1, 2000
Last modified: February 23, 2022
This is version 137 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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