UniProtKB - Q9NRZ7 (PLCC_HUMAN)
Protein
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
Gene
AGPAT3
Organism
Homo sapiens (Human)
Status
Functioni
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:21173190). Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor (PubMed:21173190). Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA (PubMed:21173190). Has a preference for arachidonoyl-CoA as a donor (By similarity). Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity).By similarity1 Publication
Catalytic activityi
- a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA1 PublicationEC:2.3.1.511 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + pentadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + heptadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + nonadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholine + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) = 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine = 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-heptadecanoyl-sn-glycero-3-phosphate = 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate = 1-O-(9Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoABy similarityThis reaction proceeds in the forwardBy similarity direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) = a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoABy similarityThis reaction proceeds in the forwardBy similarity direction.
Kineticsi
- KM=4.78 µM for LPA sn-1 C18:11 Publication
- KM=21.53 µM for C18:1-CoA1 Publication
- Vmax=6.35 nmol/min/mg enzyme toward LPA sn-1 C18:11 Publication
- Vmax=0.74 nmol/min/mg enzyme toward C18:1-CoA1 Publication
: CDP-diacylglycerol biosynthesis Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.Proteins known to be involved in the 3 steps of the subpathway in this organism are:
- Glycerol-3-phosphate acyltransferase 1, mitochondrial, Glycerol-3-phosphate acyltransferase 2, mitochondrial (GPAT2), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 1, mitochondrial (DKFZp451B1115), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 4 (GPAT4), Glycerol-3-phosphate acyltransferase 3 (GPAT3)
- 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5), 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3), 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1), 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2), Lysocardiolipin acyltransferase 1 (LCLAT1), 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (AGPAT4)
- Phosphatidate cytidylyltransferase 1 (CDS1), Phosphatidate cytidylyltransferase 2 (CDS2), Phosphatidate cytidylyltransferase, mitochondrial (TAMM41), CDP-diacylglycerol synthase (TAMM41), CDP-diacylglycerol synthase (TAMM41), Phosphatidate cytidylyltransferase (CDS1), Phosphatidate cytidylyltransferase, Phosphatidate cytidylyltransferase, Phosphatidate cytidylyltransferase, CDP-diacylglycerol synthase (TAMM41), CDP-diacylglycerol synthase (TAMM41), Phosphatidate cytidylyltransferase
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.
GO - Molecular functioni
- 1-acylglycerol-3-phosphate O-acyltransferase activity Source: UniProtKB
- transferase activity, transferring acyl groups Source: GO_Central
GO - Biological processi
- CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
- phosphatidic acid biosynthetic process Source: Reactome
- phospholipid biosynthetic process Source: UniProtKB
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Enzyme and pathway databases
BioCyci | MetaCyc:HS08470-MONOMER |
BRENDAi | 2.3.1.51, 2681 |
PathwayCommonsi | Q9NRZ7 |
Reactomei | R-HSA-1483166, Synthesis of PA R-HSA-6811436, COPI-independent Golgi-to-ER retrograde traffic |
SIGNORi | Q9NRZ7 |
UniPathwayi | UPA00557;UER00613 |
Chemistry databases
SwissLipidsi | SLP:000000823 |
Names & Taxonomyi
Protein namesi | Recommended name: 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC:2.3.1.511 Publication)Alternative name(s): 1-acylglycerol-3-phosphate O-acyltransferase 3 Short name: 1-AGP acyltransferase 3 Short name: 1-AGPAT 3 Lysophosphatidic acid acyltransferase gamma Short name: LPAAT-gamma |
Gene namesi | Name:AGPAT3 Synonyms:LPAAT3 ORF Names:UNQ759/PRO1490 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000160216.18 |
HGNCi | HGNC:326, AGPAT3 |
MIMi | 614794, gene |
neXtProti | NX_Q9NRZ7 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 2 Publications; Multi-pass membrane protein Sequence analysis
Nucleus
- Nucleus envelope 1 Publication
Endoplasmic reticulum
- endoplasmic reticulum Source: UniProtKB
- endoplasmic reticulum membrane Source: UniProtKB
Golgi apparatus
- Golgi membrane Source: Reactome
Nucleus
- nuclear envelope Source: UniProtKB
Plasma Membrane
- plasma membrane Source: UniProtKB
Other locations
- endomembrane system Source: GO_Central
- integral component of membrane Source: UniProtKB-KW
- membrane Source: UniProtKB
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 124 | Cytoplasmic1 PublicationAdd BLAST | 124 | |
Transmembranei | 125 – 145 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 146 – 316 | Lumenal1 PublicationAdd BLAST | 171 | |
Transmembranei | 317 – 339 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 340 – 376 | Cytoplasmic1 PublicationAdd BLAST | 37 |
Keywords - Cellular componenti
Endoplasmic reticulum, Membrane, NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 56894 |
OpenTargetsi | ENSG00000160216 |
PharmGKBi | PA24623 |
Miscellaneous databases
Pharosi | Q9NRZ7, Tbio |
Polymorphism and mutation databases
BioMutai | AGPAT3 |
DMDMi | 12643817 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000208194 | 1 – 376 | 1-acyl-sn-glycerol-3-phosphate acyltransferase gammaAdd BLAST | 376 |
Proteomic databases
jPOSTi | Q9NRZ7 |
MassIVEi | Q9NRZ7 |
MaxQBi | Q9NRZ7 |
PaxDbi | Q9NRZ7 |
PeptideAtlasi | Q9NRZ7 |
PRIDEi | Q9NRZ7 |
ProteomicsDBi | 82447 [Q9NRZ7-1] 82448 [Q9NRZ7-2] 82449 [Q9NRZ7-3] |
PTM databases
iPTMneti | Q9NRZ7 |
PhosphoSitePlusi | Q9NRZ7 |
SwissPalmi | Q9NRZ7 |
Expressioni
Tissue specificityi
Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver.1 Publication
Gene expression databases
Bgeei | ENSG00000160216, Expressed in primary visual cortex and 220 other tissues |
ExpressionAtlasi | Q9NRZ7, baseline and differential |
Genevisiblei | Q9NRZ7, HS |
Organism-specific databases
HPAi | ENSG00000160216, Tissue enhanced (skeletal) |
Interactioni
Binary interactionsi
Hide detailsQ9NRZ7
Protein-protein interaction databases
BioGRIDi | 121224, 54 interactors |
IntActi | Q9NRZ7, 32 interactors |
MINTi | Q9NRZ7 |
STRINGi | 9606.ENSP00000381140 |
Miscellaneous databases
RNActi | Q9NRZ7, protein |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 96 – 101 | HXXXXD motifBy similarity | 6 |
Domaini
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.By similarity
Sequence similaritiesi
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1505, Eukaryota |
GeneTreei | ENSGT00950000182836 |
InParanoidi | Q9NRZ7 |
OMAi | EQECANW |
OrthoDBi | 959325at2759 |
PhylomeDBi | Q9NRZ7 |
TreeFami | TF314065 |
Family and domain databases
InterProi | View protein in InterPro IPR032098, Acyltransf_C IPR002123, Plipid/glycerol_acylTrfase |
Pfami | View protein in Pfam PF16076, Acyltransf_C, 1 hit PF01553, Acyltransferase, 1 hit |
SMARTi | View protein in SMART SM00563, PlsC, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q9NRZ7-1) [UniParc]FASTAAdd to basket
Also known as: Gamma-1
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGLLAFLKTQ FVLHLLVGFV FVVSGLVINF VQLCTLALWP VSKQLYRRLN
60 70 80 90 100
CRLAYSLWSQ LVMLLEWWSC TECTLFTDQA TVERFGKEHA VIILNHNFEI
110 120 130 140 150
DFLCGWTMCE RFGVLGSSKV LAKKELLYVP LIGWTWYFLE IVFCKRKWEE
160 170 180 190 200
DRDTVVEGLR RLSDYPEYMW FLLYCEGTRF TETKHRVSME VAAAKGLPVL
210 220 230 240 250
KYHLLPRTKG FTTAVKCLRG TVAAVYDVTL NFRGNKNPSL LGILYGKKYE
260 270 280 290 300
ADMCVRRFPL EDIPLDEKEA AQWLHKLYQE KDALQEIYNQ KGMFPGEQFK
310 320 330 340 350
PARRPWTLLN FLSWATILLS PLFSFVLGVF ASGSPLLILT FLGFVGAASF
360 370
GVRRLIGVTE IEKGSSYGNQ EFKKKE
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketC9JL26 | C9JL26_HUMAN | 1-acyl-sn-glycerol-3-phosphate acyl... | AGPAT3 | 255 | Annotation score: | ||
C9J184 | C9J184_HUMAN | 1-acyl-sn-glycerol-3-phosphate acyl... | AGPAT3 | 128 | Annotation score: | ||
C9JK35 | C9JK35_HUMAN | 1-acyl-sn-glycerol-3-phosphate acyl... | AGPAT3 | 38 | Annotation score: | ||
C9JQX8 | C9JQX8_HUMAN | 1-acyl-sn-glycerol-3-phosphate acyl... | AGPAT3 | 79 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 74 | T → P in CAD38635 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 358 – 376 | VTEIE…FKKKE → ESLEPGRWRLQ in AAQ89067 (PubMed:12975309).CuratedAdd BLAST | 19 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_005072 | 1 – 62 | Missing in isoform 2. 1 PublicationAdd BLAST | 62 | |
Alternative sequenceiVSP_013144 | 1 – 60 | MGLLA…SLWSQ → MQSGGSLPFCCYLPSVSSQL LLRESYCNFIKRTQCKSSKL MFSRDFLSGQKYCRCLLWAL PDHPRRRGPTSANALPLSAE in isoform 3. 1 PublicationAdd BLAST | 60 |
Sequence databases
Genome annotation databases
Ensembli | ENST00000291572; ENSP00000291572; ENSG00000160216 [Q9NRZ7-1] ENST00000327505; ENSP00000332989; ENSG00000160216 [Q9NRZ7-1] ENST00000398058; ENSP00000381135; ENSG00000160216 [Q9NRZ7-1] ENST00000398061; ENSP00000381138; ENSG00000160216 [Q9NRZ7-1] ENST00000398063; ENSP00000381140; ENSG00000160216 [Q9NRZ7-1] ENST00000546158; ENSP00000443510; ENSG00000160216 [Q9NRZ7-1] |
GeneIDi | 56894 |
KEGGi | hsa:56894 |
UCSCi | uc002zdv.4, human [Q9NRZ7-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 121224, 54 interactors |
IntActi | Q9NRZ7, 32 interactors |
MINTi | Q9NRZ7 |
STRINGi | 9606.ENSP00000381140 |
Chemistry databases
SwissLipidsi | SLP:000000823 |
PTM databases
iPTMneti | Q9NRZ7 |
PhosphoSitePlusi | Q9NRZ7 |
SwissPalmi | Q9NRZ7 |
Polymorphism and mutation databases
BioMutai | AGPAT3 |
DMDMi | 12643817 |
Proteomic databases
jPOSTi | Q9NRZ7 |
MassIVEi | Q9NRZ7 |
MaxQBi | Q9NRZ7 |
PaxDbi | Q9NRZ7 |
PeptideAtlasi | Q9NRZ7 |
PRIDEi | Q9NRZ7 |
ProteomicsDBi | 82447 [Q9NRZ7-1] 82448 [Q9NRZ7-2] 82449 [Q9NRZ7-3] |
Protocols and materials databases
Antibodypediai | 24081, 156 antibodies |
DNASUi | 56894 |
Genome annotation databases
Ensembli | ENST00000291572; ENSP00000291572; ENSG00000160216 [Q9NRZ7-1] ENST00000327505; ENSP00000332989; ENSG00000160216 [Q9NRZ7-1] ENST00000398058; ENSP00000381135; ENSG00000160216 [Q9NRZ7-1] ENST00000398061; ENSP00000381138; ENSG00000160216 [Q9NRZ7-1] ENST00000398063; ENSP00000381140; ENSG00000160216 [Q9NRZ7-1] ENST00000546158; ENSP00000443510; ENSG00000160216 [Q9NRZ7-1] |
GeneIDi | 56894 |
KEGGi | hsa:56894 |
UCSCi | uc002zdv.4, human [Q9NRZ7-1] |
Organism-specific databases
CTDi | 56894 |
DisGeNETi | 56894 |
EuPathDBi | HostDB:ENSG00000160216.18 |
GeneCardsi | AGPAT3 |
HGNCi | HGNC:326, AGPAT3 |
HPAi | ENSG00000160216, Tissue enhanced (skeletal) |
MIMi | 614794, gene |
neXtProti | NX_Q9NRZ7 |
OpenTargetsi | ENSG00000160216 |
PharmGKBi | PA24623 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1505, Eukaryota |
GeneTreei | ENSGT00950000182836 |
InParanoidi | Q9NRZ7 |
OMAi | EQECANW |
OrthoDBi | 959325at2759 |
PhylomeDBi | Q9NRZ7 |
TreeFami | TF314065 |
Enzyme and pathway databases
UniPathwayi | UPA00557;UER00613 |
BioCyci | MetaCyc:HS08470-MONOMER |
BRENDAi | 2.3.1.51, 2681 |
PathwayCommonsi | Q9NRZ7 |
Reactomei | R-HSA-1483166, Synthesis of PA R-HSA-6811436, COPI-independent Golgi-to-ER retrograde traffic |
SIGNORi | Q9NRZ7 |
Miscellaneous databases
BioGRID-ORCSi | 56894, 7 hits in 848 CRISPR screens |
ChiTaRSi | AGPAT3, human |
GeneWikii | AGPAT3 |
GenomeRNAii | 56894 |
Pharosi | Q9NRZ7, Tbio |
PROi | PR:Q9NRZ7 |
RNActi | Q9NRZ7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000160216, Expressed in primary visual cortex and 220 other tissues |
ExpressionAtlasi | Q9NRZ7, baseline and differential |
Genevisiblei | Q9NRZ7, HS |
Family and domain databases
InterProi | View protein in InterPro IPR032098, Acyltransf_C IPR002123, Plipid/glycerol_acylTrfase |
Pfami | View protein in Pfam PF16076, Acyltransf_C, 1 hit PF01553, Acyltransferase, 1 hit |
SMARTi | View protein in SMART SM00563, PlsC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PLCC_HUMAN | |
Accessioni | Q9NRZ7Primary (citable) accession number: Q9NRZ7 Secondary accession number(s): D3DSL2 Q9NRZ6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 11, 2001 |
Last sequence update: | October 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 168 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families - Human chromosome 21
Human chromosome 21: entries, gene names and cross-references to MIM