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Entry version 118 (13 Feb 2019)
Sequence version 4 (18 May 2010)
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Protein

Protein FAM114A2

Gene

FAM114A2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • purine nucleotide binding Source: UniProtKB

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6802952 Signaling by BRAF and RAF fusions

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM114A2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM114A2
Synonyms:C5orf3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000055147.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1333 FAM114A2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NRY5

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000055147

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162385716

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM114A2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296439475

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002745641 – 505Protein FAM114A2Add BLAST505

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei87PhosphoserineCombined sources1
Modified residuei146PhosphoserineCombined sources1
Modified residuei209PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NRY5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NRY5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NRY5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NRY5

PeptideAtlas

More...
PeptideAtlasi
Q9NRY5

PRoteomics IDEntifications database

More...
PRIDEi
Q9NRY5

ProteomicsDB human proteome resource

More...
ProteomicsDBi
82443

2D gel databases

REPRODUCTION-2DPAGE

More...
REPRODUCTION-2DPAGEi
IPI00329662

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NRY5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NRY5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000055147 Expressed in 212 organ(s), highest expression level in kidney

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NRY5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NRY5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035869
HPA035870

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116040, 21 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NRY5, 12 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000341597

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9NRY5

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili268 – 295Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi297 – 302Poly-Glu6

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM114 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHQB Eukaryota
ENOG411029H LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010054

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000059573

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG056879

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NRY5

Identification of Orthologs from Complete Genome Data

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OMAi
LFENYCG

Database of Orthologous Groups

More...
OrthoDBi
947469at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NRY5

TreeFam database of animal gene trees

More...
TreeFami
TF324360

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007998 DUF719

The PANTHER Classification System

More...
PANTHERi
PTHR12842 PTHR12842, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05334 DUF719, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

Q9NRY5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDKDDIETP LLTEAAPILE DGNCEPAKNS ESVDQGAKPE SKSEPVVSTR
60 70 80 90 100
KRPETKPSSD LETSKVLPIQ DNVSKDVPQT RWGYWGSWGK SILSSASATV
110 120 130 140 150
ATVGQGISNV IEKAETSLGI PGPSEISTEV KYVAGETNAK ENENSSPVAG
160 170 180 190 200
AFGVFSTIST AVQSTGKSVI SGGLDALEFI GKKTMDVIAE GDPGFKRTKG
210 220 230 240 250
LMNRNATLSQ VLREAKEKEE IRTSNEVTVE TDKKTHYGLL FDEFQGLSHL
260 270 280 290 300
EALEMLSQES EIKVKSILNS LSGEELETLK VELEQLKETF SLAEFCEEEE
310 320 330 340 350
EEKKGDEDFT KDITELFSQL HVSSKPEKLA RARNTAHEWI RKSLTKPLAE
360 370 380 390 400
NEEGEKQSEA ENTEQVNKNS IEDIHAFAIR SLAELTACSI ELFHKTAALV
410 420 430 440 450
LHGRKQEVTA IERSQTLSQM TIVLCKELSS LSKEFTTCLT TAGVKEMADV
460 470 480 490 500
LNPLITAVFL EASNSASYIQ DAFQLLLPVL EISLIENKIE SHRHELQGQK

PLLEH
Length:505
Mass (Da):55,468
Last modified:May 18, 2010 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE3991C42F8DCF606
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7ESJ7E7ESJ7_HUMAN
Protein FAM114A2
FAM114A2
435Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RGF9E5RGF9_HUMAN
Protein FAM114A2
FAM114A2
210Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHP2E5RHP2_HUMAN
Protein FAM114A2
FAM114A2
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RFK2E5RFK2_HUMAN
Protein FAM114A2
FAM114A2
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHI8E5RHI8_HUMAN
Protein FAM114A2
FAM114A2
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RK42E5RK42_HUMAN
Protein FAM114A2
FAM114A2
79Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RH43E5RH43_HUMAN
Protein FAM114A2
FAM114A2
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RIK7E5RIK7_HUMAN
Protein FAM114A2
FAM114A2
15Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti68P → S in AAF76523 (PubMed:10843801).Curated1
Sequence conflicti122G → S in AAF76523 (PubMed:10843801).Curated1
Sequence conflicti122G → S in BAB14952 (PubMed:14702039).Curated1
Sequence conflicti122G → S in AAH11414 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF159700 mRNA Translation: AAF76523.1
AK024664 mRNA Translation: BAB14952.1
AK313331 mRNA Translation: BAG36135.1
AC010232 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW61646.1
CH471062 Genomic DNA Translation: EAW61647.1
CH471062 Genomic DNA Translation: EAW61648.1
BC011414 mRNA Translation: AAH11414.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4323.1

NCBI Reference Sequences

More...
RefSeqi
NP_001304922.1, NM_001317993.1
NP_001304923.1, NM_001317994.1
NP_001304924.1, NM_001317995.1
NP_061161.2, NM_018691.3
XP_005268417.1, XM_005268360.4
XP_005268418.1, XM_005268361.4
XP_011535842.1, XM_011537540.2
XP_011535843.1, XM_011537541.2
XP_011535844.1, XM_011537542.2
XP_016864456.1, XM_017008967.1
XP_016864457.1, XM_017008968.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.166551

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000351797; ENSP00000341597; ENSG00000055147
ENST00000520667; ENSP00000430384; ENSG00000055147
ENST00000522858; ENSP00000430489; ENSG00000055147

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10827

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10827

UCSC genome browser

More...
UCSCi
uc003lvb.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF159700 mRNA Translation: AAF76523.1
AK024664 mRNA Translation: BAB14952.1
AK313331 mRNA Translation: BAG36135.1
AC010232 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW61646.1
CH471062 Genomic DNA Translation: EAW61647.1
CH471062 Genomic DNA Translation: EAW61648.1
BC011414 mRNA Translation: AAH11414.1
CCDSiCCDS4323.1
RefSeqiNP_001304922.1, NM_001317993.1
NP_001304923.1, NM_001317994.1
NP_001304924.1, NM_001317995.1
NP_061161.2, NM_018691.3
XP_005268417.1, XM_005268360.4
XP_005268418.1, XM_005268361.4
XP_011535842.1, XM_011537540.2
XP_011535843.1, XM_011537541.2
XP_011535844.1, XM_011537542.2
XP_016864456.1, XM_017008967.1
XP_016864457.1, XM_017008968.1
UniGeneiHs.166551

3D structure databases

ProteinModelPortaliQ9NRY5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116040, 21 interactors
IntActiQ9NRY5, 12 interactors
STRINGi9606.ENSP00000341597

PTM databases

iPTMnetiQ9NRY5
PhosphoSitePlusiQ9NRY5

Polymorphism and mutation databases

BioMutaiFAM114A2
DMDMi296439475

2D gel databases

REPRODUCTION-2DPAGEiIPI00329662

Proteomic databases

EPDiQ9NRY5
jPOSTiQ9NRY5
MaxQBiQ9NRY5
PaxDbiQ9NRY5
PeptideAtlasiQ9NRY5
PRIDEiQ9NRY5
ProteomicsDBi82443

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10827
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000351797; ENSP00000341597; ENSG00000055147
ENST00000520667; ENSP00000430384; ENSG00000055147
ENST00000522858; ENSP00000430489; ENSG00000055147
GeneIDi10827
KEGGihsa:10827
UCSCiuc003lvb.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10827
EuPathDBiHostDB:ENSG00000055147.17

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM114A2

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0005337
HGNCiHGNC:1333 FAM114A2
HPAiHPA035869
HPA035870
neXtProtiNX_Q9NRY5
OpenTargetsiENSG00000055147
PharmGKBiPA162385716

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IHQB Eukaryota
ENOG411029H LUCA
GeneTreeiENSGT00390000010054
HOGENOMiHOG000059573
HOVERGENiHBG056879
InParanoidiQ9NRY5
OMAiLFENYCG
OrthoDBi947469at2759
PhylomeDBiQ9NRY5
TreeFamiTF324360

Enzyme and pathway databases

ReactomeiR-HSA-6802952 Signaling by BRAF and RAF fusions

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM114A2 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
C5orf3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10827

Protein Ontology

More...
PROi
PR:Q9NRY5

Gene expression databases

BgeeiENSG00000055147 Expressed in 212 organ(s), highest expression level in kidney
ExpressionAtlasiQ9NRY5 baseline and differential
GenevisibleiQ9NRY5 HS

Family and domain databases

InterProiView protein in InterPro
IPR007998 DUF719
PANTHERiPTHR12842 PTHR12842, 1 hit
PfamiView protein in Pfam
PF05334 DUF719, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1142_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NRY5
Secondary accession number(s): B2R8D8, Q9H7E0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 18, 2010
Last modified: February 13, 2019
This is version 118 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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