PHPT1

Functionⁱ

Exhibits phosphohistidine phosphatase activity.2 Publications

Catalytic activityⁱ

A [protein]-N-phospho-L-histidine + H₂O = a [protein]-L-histidine + phosphate.2 Publications

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Binding siteⁱ	21	Substrate1 Publication		1
Active siteⁱ	53	Proton acceptor1 Publication		1

GO - Molecular functionⁱ

calcium channel inhibitor activity
Source: BHF-UCL
Inferred from direct assayⁱ
- 18796614
ion channel binding
Source: BHF-UCL
Inferred from physical interactionⁱ
- 18796614
protein histidine phosphatase activity
Source: BHF-UCL
Inferred from direct assayⁱ

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of ATP citrate synthase activity
Source: BHF-UCL
Inferred from direct assayⁱ
- 18656514
negative regulation of lyase activity
Source: BHF-UCL
Inferred from direct assayⁱ
- 20110805
- 20501872
negative regulation of T cell receptor signaling pathway
Source: BHF-UCL
Inferred from mutant phenotypeⁱ
- 18796614
peptidyl-histidine dephosphorylation
Source: BHF-UCL
Inferred from direct assayⁱ
- 16219293
- 19138678
positive regulation of cell motility
Source: BHF-UCL
Inferred from mutant phenotypeⁱ
- 19344975
positive regulation of insulin secretion involved in cellular response to glucose stimulus Source: Ensembl
protein dephosphorylation
Source: BHF-UCL
Inferred from direct assayⁱ
- 20501872
regulation of actin cytoskeleton reorganization
Source: BHF-UCL
Inferred from mutant phenotypeⁱ
- 19344975

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Hydrolase, Protein phosphatase

Molecular function

Hydrolase, Protein phosphatase

Enzyme and pathway databases

BioCycⁱ	MetaCyc:ENSG00000054148-MONOMER

BioCycⁱ

MetaCyc:ENSG00000054148-MONOMER

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 14 kDa phosphohistidine phosphatase1 Publication (EC:3.9.1.32 Publications) Alternative name(s): Phosphohistidine phosphatase 11 Publication Short name: PHPT11 Publication Protein histidine phosphatase1 Publication Short name: PHP1 Publication Protein janus-A homolog
Gene namesⁱ	Name:PHPT1 Synonyms:PHP14 ORF Names:CGI-202, HSPC141
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 9

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000054148.17
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:30033 PHPT1
MIMⁱ	610167 gene
neXtProtⁱ	NX_Q9NRX4

Keywords - Cellular componentⁱ

Cytoplasm

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Length
Mutagenesisⁱ	21	K → A: Decreased affinity for substrate and strongly reduced catalytic activity. 1 Publication	1
Mutagenesisⁱ	45	R → A: Slightly decreased affinity for substrate, but no effect on catalytic activity. 2 Publications	1
Mutagenesisⁱ	53	H → A: Loss of activity. 2 Publications	1
Mutagenesisⁱ	78	R → A: Decreased affinity for substrate and reduced catalytic activity. 2 Publications	1
Mutagenesisⁱ	94	S → A: Decreased affinity for substrate and strongly reduced catalytic activity.	1
Mutagenesisⁱ	102	H → A: Decreased affinity for substrate and slightly reduced catalytic activity. 2 Publications	1

Organism-specific databases

DisGeNET More...DisGeNETⁱ	29085
Open Targets More...OpenTargetsⁱ	ENSG00000054148
PharmGKBⁱ	PA134948141

Polymorphism and mutation databases

DMDMⁱ	25008934

DMDMⁱ

25008934

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		RemovedCombined sources1 Publication
ChainⁱPRO_0000206152	2 – 125	14 kDa phosphohistidine phosphataseAdd BLAST		124

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	2	N-acetylalanineCombined sources		1

Keywords - PTMⁱ

Acetylation

Proteomic databases

EPDⁱ	Q9NRX4
PaxDbⁱ	Q9NRX4
PeptideAtlas More...PeptideAtlasⁱ	Q9NRX4
PRIDEⁱ	Q9NRX4
ProteomicsDBⁱ	82435 82436 [Q9NRX4-2]
TopDownProteomicsⁱ	Q9NRX4-1 [Q9NRX4-1]

PTM databases

DEPODⁱ	Q9NRX4
iPTMnetⁱ	Q9NRX4
PhosphoSitePlusⁱ	Q9NRX4

Expressionⁱ

Tissue specificityⁱ

Expressed abundantly in heart and skeletal muscle.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000054148 Expressed in 181 organ(s), highest expression level in apex of heart
CleanExⁱ	HS_PHPT1
ExpressionAtlasⁱ	Q9NRX4 baseline and differential
Genevisibleⁱ	Q9NRX4 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB013584 HPA020952

HPAⁱ

CAB013584
HPA020952

Interactionⁱ

Subunit structureⁱ

Monomer.1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
KCNN4	O15554	2	EBI-740955,EBI-2924473

With

Entry

#Exp.

IntAct

Notes

KCNN4

O15554

2

EBI-740955,EBI-2924473

GO - Molecular functionⁱ

ion channel binding
Source: BHF-UCL
Inferred from physical interactionⁱ
- 18796614

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	118854, 20 interactors
Database of interacting proteins More...DIPⁱ	DIP-48597N
IntActⁱ	Q9NRX4, 6 interactors
STRINGⁱ	9606.ENSP00000247665

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	6 – 8	Combined sources	3
Beta strandⁱ	11 – 14	Combined sources	4
Beta strandⁱ	17 – 28	Combined sources	12
Helixⁱ	31 – 33	Combined sources	3
Beta strandⁱ	40 – 46	Combined sources	7
Helixⁱ	53 – 66	Combined sources	14
Beta strandⁱ	70 – 82	Combined sources	13
Turnⁱ	83 – 86	Combined sources	4
Beta strandⁱ	87 – 91	Combined sources	5
Turnⁱ	95 – 97	Combined sources	3
Helixⁱ	102 – 112	Combined sources	11
Beta strandⁱ	116 – 120	Combined sources	5

Show more details

3D structure databases

ProteinModelPortalⁱ	Q9NRX4
SMRⁱ	Q9NRX4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q9NRX4

EvolutionaryTraceⁱ

Q9NRX4

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	94 – 96	Substrate binding1 Publication		3

Sequence similaritiesⁱ

Belongs to the janus family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG410IZ5G Eukaryota ENOG4111SA6 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000002738
HOGENOMⁱ	HOG000231559
HOVERGENⁱ	HBG053589
InParanoidⁱ	Q9NRX4
KEGG Orthology (KO) More...KOⁱ	K01112
OMAⁱ	GWAEYHA
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G10Y7
PhylomeDBⁱ	Q9NRX4
TreeFamⁱ	TF315158

Family and domain databases

Gene3Dⁱ	3.50.20.20, 1 hit
InterProⁱ	View protein in InterPro IPR007702 Janus IPR038596 Janus_sf IPR028441 PHPT1
PANTHERⁱ	PTHR12258 PTHR12258, 1 hit PTHR12258:SF10 PTHR12258:SF10, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05005 Ocnus, 1 hit

Sequences (2)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

Isoform 1 (identifier: Q9NRX4-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAVADLALIP DVDIDSDGVF KYVLIRVHSA PRSGAPAAES KEIVRGYKWA 
        60         70         80         90        100
EYHADIYDKV SGDMQKQGCD CECLGGGRIS HQSQDKKIHV YGYSMAYGPA 
       110        120 
QHAISTEKIK AKYPDYEVTW ANDGY

Length:125

Mass (Da):13,833

Last modified:October 1, 2000 - v1

Checksum:ⁱ24F0CA2BADB78478

GO

Isoform 2 (identifier: Q9NRX4-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
96-125: AYGPAQHAISTEKIKAKYPDYEVTWANDGY → MRPTCVPLGASGPRIHHQGLWSCPARHFN

« Hide

        10         20         30         40         50
MAVADLALIP DVDIDSDGVF KYVLIRVHSA PRSGAPAAES KEIVRGYKWA 
        60         70         80         90        100
EYHADIYDKV SGDMQKQGCD CECLGGGRIS HQSQDKKIHV YGYSMMRPTC 
       110        120 
VPLGASGPRI HHQGLWSCPA RHFN

Show »

Length:124

Mass (Da):13,672

Checksum:ⁱB504A355D275D9C6

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	14	I → T in CAB66579 (PubMed:11230166).Curated	1
Sequence conflictⁱ	27	V → I in CAB66579 (PubMed:11230166).Curated	1
Sequence conflictⁱ	79	I → T in CAB66579 (PubMed:11230166).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_041159	96 – 125	AYGPA…ANDGY → MRPTCVPLGASGPRIHHQGL WSCPARHFN in isoform 2. 1 PublicationAdd BLAST		30

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF393504 mRNA Translation: AAN52504.1 AF164795 mRNA Translation: AAF80759.1 AF285119 mRNA Translation: AAG01156.1 AL136644 mRNA Translation: CAB66579.1 AL355987 Genomic DNA No translation available. CH471090 Genomic DNA Translation: EAW88289.1 BC024648 mRNA Translation: AAH24648.1 BQ922335 mRNA No translation available.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS48060.1 [Q9NRX4-2] CCDS7009.1 [Q9NRX4-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001129333.1, NM_001135861.2 [Q9NRX4-2] NP_054891.2, NM_014172.5 [Q9NRX4-1]
UniGeneⁱ	Hs.409834 Hs.731711

Genome annotation databases

Ensemblⁱ	ENST00000247665; ENSP00000247665; ENSG00000054148 [Q9NRX4-1] ENST00000371661; ENSP00000360724; ENSG00000054148 [Q9NRX4-2]
GeneIDⁱ	29085
KEGGⁱ	hsa:29085
UCSC genome browser More...UCSCⁱ	uc064xew.1 human [Q9NRX4-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9NRX4	Epididymis secretory sperm binding protein Li 132P		HUMAN		125	UniRef100_Q9NRX4
UPI0000EF7C3E		HUMAN		135

Protein	Similar proteins		Species	Score	Length	Source
Q9NRX4	14 kDa phosphohistidine phosphatase		PONAB		125	UniRef90_Q9NRX4
Epididymis secretory sperm binding protein Li 132P		HUMAN		125
Uncharacterized protein		RHIRO		127
PHPT1 isoform 3		PANTR		125
Phosphohistidine phosphatase 1		SAIBB		125
+14
Q9NRX4-2	Phosphohistidine phosphatase 1		CALJA		125	UniRef90_Q9NRX4-2
PHPT1 isoform 4		PANTR		124
Uncharacterized protein		MACMU		124
Uncharacterized protein		PAPAN		124
Uncharacterized protein		MACFA		124
+7

Protein	Similar proteins		Species	Score	Length	Source
Q9NRX4	14 kDa phosphohistidine phosphatase		PONAB		125	UniRef50_Q9NRX4
Epididymis secretory sperm binding protein Li 132P		HUMAN		125
Uncharacterized protein		RHIRO		127
Phosphohistidine phosphatase 1		GORGO		125
PHPT1 isoform 3		PANTR		125
+104
Q9NRX4-2	Phosphohistidine phosphatase 1		CALJA		125	UniRef50_Q9NRX4-2
PHPT1 isoform 4		PANTR		124
Uncharacterized protein		MACMU		124
Uncharacterized protein		PAPAN		124
Uncharacterized protein		MACFA		124
+52

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF393504 mRNA Translation: AAN52504.1 AF164795 mRNA Translation: AAF80759.1 AF285119 mRNA Translation: AAG01156.1 AL136644 mRNA Translation: CAB66579.1 AL355987 Genomic DNA No translation available. CH471090 Genomic DNA Translation: EAW88289.1 BC024648 mRNA Translation: AAH24648.1 BQ922335 mRNA No translation available.
CCDSⁱ	CCDS48060.1 [Q9NRX4-2] CCDS7009.1 [Q9NRX4-1]
RefSeqⁱ	NP_001129333.1, NM_001135861.2 [Q9NRX4-2] NP_054891.2, NM_014172.5 [Q9NRX4-1]
UniGeneⁱ	Hs.409834 Hs.731711

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2AI6	NMR	-	A	1-125	[»]
	2HW4	X-ray	1.90	A	5-125	[»]
	2NMM	X-ray	2.70	A/B/C	1-125	[»]
	2OZW	NMR	-	A	1-125	[»]
	2OZX	NMR	-	A	1-125	[»]
ProteinModelPortalⁱ	Q9NRX4
SMRⁱ	Q9NRX4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	118854, 20 interactors
DIPⁱ	DIP-48597N
IntActⁱ	Q9NRX4, 6 interactors
STRINGⁱ	9606.ENSP00000247665

PTM databases

DEPODⁱ	Q9NRX4
iPTMnetⁱ	Q9NRX4
PhosphoSitePlusⁱ	Q9NRX4

Polymorphism and mutation databases

DMDMⁱ	25008934

DMDMⁱ

25008934

Proteomic databases

EPDⁱ	Q9NRX4
PaxDbⁱ	Q9NRX4
PeptideAtlasⁱ	Q9NRX4
PRIDEⁱ	Q9NRX4
ProteomicsDBⁱ	82435 82436 [Q9NRX4-2]
TopDownProteomicsⁱ	Q9NRX4-1 [Q9NRX4-1]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	29085
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000247665; ENSP00000247665; ENSG00000054148 [Q9NRX4-1] ENST00000371661; ENSP00000360724; ENSG00000054148 [Q9NRX4-2]
GeneIDⁱ	29085
KEGGⁱ	hsa:29085
UCSCⁱ	uc064xew.1 human [Q9NRX4-1]

Organism-specific databases

CTDⁱ	29085
DisGeNETⁱ	29085
EuPathDBⁱ	HostDB:ENSG00000054148.17
GeneCardsⁱ	PHPT1
HGNCⁱ	HGNC:30033 PHPT1
HPAⁱ	CAB013584 HPA020952
MIMⁱ	610167 gene
neXtProtⁱ	NX_Q9NRX4
OpenTargetsⁱ	ENSG00000054148
PharmGKBⁱ	PA134948141
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IZ5G Eukaryota ENOG4111SA6 LUCA
GeneTreeⁱ	ENSGT00390000002738
HOGENOMⁱ	HOG000231559
HOVERGENⁱ	HBG053589
InParanoidⁱ	Q9NRX4
KOⁱ	K01112
OMAⁱ	GWAEYHA
OrthoDBⁱ	EOG091G10Y7
PhylomeDBⁱ	Q9NRX4
TreeFamⁱ	TF315158

Enzyme and pathway databases

BioCycⁱ	MetaCyc:ENSG00000054148-MONOMER

BioCycⁱ

MetaCyc:ENSG00000054148-MONOMER

Miscellaneous databases

ChiTaRSⁱ	PHPT1 human
EvolutionaryTraceⁱ	Q9NRX4
GeneWikiⁱ	PHPT1
GenomeRNAiⁱ	29085
Protein Ontology More...PROⁱ	PR:Q9NRX4
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000054148 Expressed in 181 organ(s), highest expression level in apex of heart
CleanExⁱ	HS_PHPT1
ExpressionAtlasⁱ	Q9NRX4 baseline and differential
Genevisibleⁱ	Q9NRX4 HS

Family and domain databases

Gene3Dⁱ	3.50.20.20, 1 hit
InterProⁱ	View protein in InterPro IPR007702 Janus IPR038596 Janus_sf IPR028441 PHPT1
PANTHERⁱ	PTHR12258 PTHR12258, 1 hit PTHR12258:SF10 PTHR12258:SF10, 1 hit
Pfamⁱ	View protein in Pfam PF05005 Ocnus, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	PHP14_HUMAN
Accessionⁱ	Q9NRX4Primary (citable) accession number: Q9NRX4 Secondary accession number(s): B1AMX0, B1AMX1, Q9H0Y3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
	Last sequence update:	October 1, 2000
	Last modified:	September 12, 2018
	This is version 154 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
SIMILARITY comments
Index of protein domains and families
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9NRX4 (PHP14_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

14 kDa phosphohistidine phosphatase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Cytosol

Extracellular region or secreted

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ